Weight Polybrominated Diphenyl Ethers Research Articles

Uptake and trophic changes in polybrominated diphenyl ethers in the benthic marine food chain in southwestern British Columbia, Canada

We examined the physical and geochemical effects of sediment on the uptake of polybrominated diphenyl ethers (PBDEs) into marine sediment feeders and their transfer to higher trophic fauna. Sediment PBDEs increased with % total organic carbon (%TOC), organic carbon (OC) flux and grain size (%fines). Tissue PBDE variance was best explained ( R2 = 0.70) by sediment acid volatile sulfides (AVS), PBDEs, and organic lability and input, with the highest values near wastewater outfalls. Dry weight tissue/sediment PBDEs declined with increasing sediment PBDEs, resulting in tissue dilution (ratio <1) at >10 000 pg/g in harbours. Ratios also decreased with increasing %fines, resulting in regional differences. These patterns imply that high levels of fines and high sediment concentrations make PBDEs less bioavailable. Dry weight PBDEs increased >100× between background deposit feeders and predators (polychaetes, crabs, bottom fish, seal), but lipid normalized PBDEs barely increased (<1.3%), suggesting remarkably high uptake in low-lipid sediment feeders, and that PBDEs don’t accumulate at higher trophic levels, but lipid content does. Filter feeders had lower lipid-normalized PBDEs than deposit feeders, highlighting the importance of food resources in higher trophic fauna for bioaccumulation. The most profound congener change occurred with sediment uptake, with nona/deca-BDEs declining and tetra-hexa-BDEs increasing. Harbour sediment feeders had more deca-BDEs than other samples, suggesting PBDEs mostly pass unmodifed through them. Deca-BDEs persist patchily in all tissues, reflecting variable dependence on sediment/pelagic food.

Effect of Smoking and Caffeine Consumption on Polybrominated Diphenyl Ethers (PBDE) and Polybrominated Biphenyls (PBB)

Effect of smoking and caffeine consumption (CC) on the levels of polybrominated diphenyl ethers (PBDE) and polybrominated biphenyls (PBB) has not been adequately studied. Data from 2003–2004 National Health and Nutrition Examination Survey (n = 1013) to simultaneously evaluate the effect of smoking and CC on levels of serum 2,2',4,4'-tetrabromodiphenyl ether (PBDE-47), 2,2',4,4',5-pentabromodiphenyl ether (PBDE-99), 2,2',4,4',6-pentabromodiphenyl ether (PBDE-100), 2,2',4,4',5,5'-hexabromodiphenyl ether (PBDE-153), and their sum and 2,2',4,4',5,5'-hexabromobiphenyl (PBB-153) were used. Regression models were fitted with logs of PBDE and PBB as dependent variables and age, age2, gender, body mass index (BMI), race/ethnicity, smoking status, fish/shellfish consumption status during the last 30 d, and CC as independent variables. For lipid-adjusted models, age was negatively associated while age2 was positively associated with almost all PBDE models. The reverse was the case for PBB-153. Body mass index was found to be negatively associated with PBDE-153 and PBB-153. Levels of all whole weight PBDE increased with levels of total lipid. Smoking was not markedly associated with concentrations of either PBDE or PBB. Males displayed significantly higher levels of PBDE-153 and ΣPBDE. For the whole weight PBDE congeners 47, 99, and 100 and PBB-153, non-Hispanic black (NHB) males showed significantly higher levels than NHB females.

A novel calibration procedure for trace analytical measurements: application to the analysis of polybrominated diphenyl ethers by GC–MS

The measurement of polybrominated diphenyl ethers (PBDEs) by gas chromatography-mass spectrometry (GC-MS) is highly challenging due to existence of the analytes at trace levels and the instability of the higher molecular weight PBDEs. These properties make accurate analysis especially problematic when utilising a low-resolution 'bench-top' GC-electron impact (EI) mass spectrometer. We discuss the problems associated with the analyses of PBDEs on these common GC-EI-MS systems and present a novel approach to calibration in these circumstances. We propose that this 'mixed calibration procedure' allows analyses to be performed that would not be possible using traditional calibration techniques, and that the procedure may be applied to a wide range of applications throughout analytical science.