Weight Adults Research Articles

Contrasting patterns of host selection and performance of insect seed predators on three sympatric host plant species

Abstract Characterising host selection mechanisms and the performance of seed‐predating insects on different hosts has broad implications for ecology and applied entomology. We assessed host selection and performance of endophagous seed‐predating insects on three species of Copaifera, testing two hypotheses: (i) large‐sized trees produce larger seeds and have higher levels of seed predation than their smaller congeneric relatives, and (ii) endophagous seed‐predating insects that develop in larger‐seeded trees exhibit higher body mass, lipid content, and muscle mass as they obtain higher amount of food resources. Unpredated seeds of the large‐sized Copaifera langsdorffii showed greater mass than their smaller congeneric relatives C. arenicola and C. oblongifolia. Two species of endophagous seed‐predating beetles (Rhinochenus brevicollis and Apion sp.) were found attacking seeds of the three Copaifera species. Rhinochenus brevicollis preyed on a higher percentage of seeds than Apion sp. The shrub C. oblongifolia had the highest percentage of seed predation, contradicting our original hypothesis that larger species have a higher percentage of seed predation. Rhinochenus brevicollis preyed on a higher percentage of seeds of larger‐sized species than Apion sp. The higher dispersal ability of R. brevicollis associated with different patterns of plant species distribution may be the mechanism driving differential seed predation among Copaifera species. Adult insects that emerged from C. langsdorffii seeds showed higher body mass and lipidic content. It is likely that insects developing in larger seeds obtain a higher amount of food resources during their development. Finally, we observed a positive relationship between body weight and lipidic content in adults of R. brevicollis. We suggest that studies shedding light onto insect performance in different host‐sized seeds are necessary to understand host selection by beetles.

P31-050-23 The Relationship of Ready-to-eat Cereal Intake and Body Weight in Adults and Children: A Systematic Review

P31-050-23 The Relationship of Ready-to-eat Cereal Intake and Body Weight in Adults and Children: A Systematic Review

PTFS09-04-23 Food Resource Management and Healthy Eating Focus Associate With Diet Quality and Less Impact of COVID-19 on Body Weight in Adults From a Low-Income, Northeastern CT Community

PTFS09-04-23 Food Resource Management and Healthy Eating Focus Associate With Diet Quality and Less Impact of COVID-19 on Body Weight in Adults From a Low-Income, Northeastern CT Community

AgRP neurons are not indispensable for body weight maintenance in adult mice

In addition to their role in promoting feeding and obesity development, hypothalamic arcuate agouti-related protein/neuropeptide Y (AgRP/NPY) neurons are widely perceived to be indispensable for maintaining normal feeding and body weight in adults, and consistently, acute inhibition of AgRP neurons is known to reduce short-term food intake. Here, we adopted complementary methods to achieve nearly complete ablation of arcuate AgRP/NPY neurons in adult mice and report that lesioning arcuate AgRP/NPY neurons in adult mice causes no apparent alterations in ad libitum feeding or body weight. Consistent with previous studies, loss of AgRP/NPY neurons blunts fasting refeeding. Thus, our studies show that AgRP/NPY neurons are not required for maintaining ad libitum feeding or body weight homeostasis in adult mice.

Effect of Intermittent Fasting versus Continuous Caloric Restriction on Body Weight and Metabolic Parameters in Adults with Overweight or Obesity: A Narrative Review

AbstractObesity and type 2 diabetes have reached epidemic proportions worldwide, including the Middle East and North Africa region. Intermittent fasting (IF) has been increasingly used to manage overweight/obesity and its metabolic complications. Physiologically, IF shifts the body's metabolism into ketosis (the metabolic switch) and induces cellular changes, which have a theoretical benefit over and above continuous caloric restriction (CCR). In this narrative overview of IF, the focus is on summarizing studies that compare IF to CCR in adults with overweight or obesity. The most commonly practiced types of IF (5:2, the alternate day fast, and the time-restricted eating) were included. Nine studies of 1-year duration or longer, with weight loss as the primary outcome, were summarized. The effect on body weight and improved metabolic parameters such as blood pressure, glycemic indicators, and lipid profile are described. Overall, IF was well tolerated and effective for weight loss in a manner comparable to CCR. The benefits were similar among adults with type 2 diabetes. There were no additional metabolic effects or benefits over and above CCR. However, more studies are needed to address specific details of IF, such as the type and timing of fasting and its application to different populations. In conclusion, IF is safe and beneficial for weight loss in adults with overweight/obesity with or without diabetes. It can be used as an alternative to CCR.

OR14-01-23 Effect of 8-Hour Time Restricted Eating Versus Daily Calorie Restriction on Body Weight and Glycemic Control in Adults With Type 2 Diabetes

OR14-01-23 Effect of 8-Hour Time Restricted Eating Versus Daily Calorie Restriction on Body Weight and Glycemic Control in Adults With Type 2 Diabetes

1269-P: Trajectories of MicroRNAs Are Associated with Trajectories of Weight but Not Fasting Blood Glucose in the Diabetes Prevention Program Trial

Introduction: Circulating microRNAs (miRs) are emerging as promising biomarkers of risk for type 2 diabetes (T2D) and responses to risk-reduction interventions, but no prior study has examined longitudinal associations between miRs and fasting blood glucose (FBG) or weight in adults at high risk for T2D. Prior studies have been cross-sectional or only measured longitudinal outcomes. We determined the association between longitudinal trajectories of miRs, FBG, and weight in a subset of participants from the Diabetes Prevention Program (DPP). Methods: This study was a secondary analysis of a subset of participants (N=150) from DPP. A custom Fireplex assay was used to quantify 58 miRs from banked plasma samples collected at baseline, 1-year, and 2-years. Generalized linear mixed models were used to analyze associations between the miRs, FBG (mg/dL), and weight (kg) over time, adjusting for covariates (i.e., age, body mass index, race or ethnicity, gender, trial arm, and high density lipoprotein cholesterol). The Benjamini-Hochberg false discovery rate method was used to adjust for multiple comparisons. Results: The sample was 73% female, 19% Black, 14% Hispanic, and mean age was 51 ± 11 years. At baseline, the participants were normotensive, obese, and had dyslipidemia and prediabetes. After adjusting for multiple comparisons, 39 miRs were significantly associated with weight, of which 12 miRs (let-7c-5p, miR-1066-5p, miR-1287-5p, miR-133b, miR-15a-5p, miR-15b-5p, miR-181c-3p, miR-197-5p, miR-23b-5p, miR-296-5p, miR-877-5p, miR-98-5p) remained significant after adjusting for covariates. In the FBG model, none of the miRs were significant. Conclusions: Twelve miRs were associated with longitudinal weight but no miRs were associated with FBG trajectories in a subset of participants from the DPP trial. These miRs may provide mechanistic, diagnostic, or therapeutic insights about T2D prevention. Disclosure K.A.Lewis: None. J.C.Florez: Consultant; AstraZeneca, Novo Nordisk, Other Relationship; AstraZeneca, Merck & Co., Inc. B.Aouizerat: None. A.M.Kanaya: None. E.Flowers: None. Funding National Institute of Diabetes and Digestive and Kidney Diseases (R01DK124228, X01DK115999)

43-LB: Preliminary Evidence of the Validity of a Measure to Assess Diet Acceptability—the Advancing Care for Type 1 Diabetes and Obesity Network (ACT1ON) Study

Diet acceptability is widely considered to be an important driver of behavioral adherence and health benefits in dietary interventions, yet there is an absence of measures with evidence of validity to assess this construct and guide decision-making. Informed by existing literature and content validity appraisal of subject matter experts, we developed and evaluated the validity of a five-item measure of diet acceptability (total score range: 5-20, total score >10 = “unacceptable”) with Likert response options (1- Strongly Agree, 2- Agree, 3- Disagree, 4- Strongly Disagree), which we administered six times during a 10.5 month Sequential, Multiple Assignment, Randomized Trial pilot that tested effects of three diets on weight and glycemic management in adults 19-30 years with type 1 diabetes ≥1 year (n=68, HbA1c <13%, BMI: 27-39). To maximize sample size (n=51), preliminary validity analyses relied predominantly on data from the first diet period (0-3 months). Greater diet acceptability according to continuous and dichotomous total and individual item scores at 3 months was associated with greater weight loss 0-3 months (e.g., total score ≤10 was associated with 2.4kg more weight loss [95% CI: 0.6, 4.2; p=0.01; n=48]). Cronbach’s α was 0.93. Exploratory factor analysis supported a 1-factor structure, explaining 99.7% of common variance. High item-total correlations (0.72 - 0.87), average inter-item correlation (0.88), and item - factor correlations (0.75 - 0.93), together with criterion validity analyses suggest item redundancy and indicate item 1 (i.e., “I am satisfied with the diet that I am currently on”) shares the strongest association with the underlying construct. Our analyses indicate robust preliminary evidence of reliability and validity of the five-item measure, while also suggesting potential adequacy of item 1 to assess the construct and minimize participant response burden in future studies that employ the measure. Disclosure A. Cristello sarteau: None. D. Igudesman: None. D. M. Maahs: Advisory Panel; Medtronic, LifeScan Diabetes Institute, MannKind Corporation, Consultant; Abbott, Research Support; Dexcom, Inc. R. E. Pratley: Other Relationship; Bayer Inc., Corcept Therapeutics, Dexcom, Inc., Gasherbrum Bio, Inc., Hanmi Pharm. Co., Ltd., Hengrui (USA) Ltd., Merck Sharp & Dohme Corp., Novo Nordisk, Pfizer Inc., Rivus Pharmaceuticals Inc., Sanofi, Scohia Pharma Inc., Sun Pharmaceutical Industries Ltd. E. J. Mayer-davis: None. Funding Clinical Trial Registration (NCT03651622)

614-P: Effect of Non-nutritive Sweetener Sucralose on Cardiometabolic Risk Factors among Overweight and Obese Adults in India—A Randomized Clinical Trial

Background: The aim of this free living, randomized parallel arm study was to evaluate the effect of replacing added sugar in beverages with non-nutritive sweetener (NNS)- Sucralose on body weight and metabolic factors in overweight and obese adults. Method: Adults aged 25-50 years with BMI ≥23 kg/m2, were randomized into Intervention arm (replacement of sugar with NNS) and Control arm (no replacement) for a period of 12 weeks. Change in anthropometric and biochemical measurements were analysed using standard methods. Results: Data of 154 subjects, was analyzed; significant reduction in waist circumference (p=0.01), fasting blood glucose (p<0.001), HbA1C (p =0.02), total Cholesterol/HDL cholesterol ratio (p=0.03), visceral adiposity index (p=0.04), HOMA IR (p=0.03), Triglyceride/glucose Index (p=0.04) & increase in HDL cholesterol (p=0.004) were seen at the end of trial in the Intervention arm. There was non-significant reduction in body fat, BMI, lipid accumulation product and high sensitivity CRP. Plasma sucralose analyzed in a subset of participants was undetectable indicating sucralose is not systematically absorbed. Conclusion: In overweight and obese participants, replacement with NNS, helps in reducing adiposity indices, along with improvement in cardio metabolic parameters. Disclosure V.Mohan: None. K.Kamala: None. A.Kuzhanthaivelu: None. G.Rajagopal: None. K.Vasudevan: None. G.Nagamuthu: None. D.Shekinah: None. R.Unnikrishnan: None. R.Anjana: None. S.Vasudevan: None.

Machine learning approach to predict body weight in adults.

Obesity is an established risk factor for non-communicable diseases such as type 2 diabetes mellitus, hypertension and cardiovascular disease. Thus, weight control is a key factor in the prevention of non-communicable diseases. A simple and quick method to predict weight change over a few years could be helpful for weight management in clinical settings. We examined the ability of a machine learning model that we constructed to predict changes in future body weight over 3 years using big data. Input in the machine learning model were three-year data on 50,000 Japanese persons (32,977 men) aged 19-91 years who underwent annual health examinations. The predictive formulas that used heterogeneous mixture learning technology (HMLT) to predict body weight in the subsequent 3 years were validated for 5,000 persons. The root mean square error (RMSE) was used to evaluate accuracy compared with multiple regression. The machine learning model utilizing HMLT automatically generated five predictive formulas. The influence of lifestyle on body weight was found to be large in people with a high body mass index (BMI) at baseline (BMI ≥29.93 kg/m2) and in young people (<24 years) with a low BMI (BMI <23.44 kg/m2). The RMSE was 1.914 in the validation set which reflects ability comparable to that of the multiple regression model of 1.890 (p = 0.323). The HMLT-based machine learning model could successfully predict weight change over 3 years. Our model could automatically identify groups whose lifestyle profoundly impacted weight loss and factors the influenced body weight change in individuals. Although this model must be validated in other populations, including other ethnic groups, before being widely implemented in global clinical settings, results suggested that this machine learning model could contribute to individualized weight management.

Results of semaglutide in patients older than 70 years, a real-world study of efficacy and safety.

The aim of this study is to investigate the use of once-weekly semaglutide in a real population of patients with type 2 diabetes mellitus (T2DM) over 70 years in two Spanish hospitals. An observational, retrospective, and multicenter clinical study was designed. It included 60 patients with T2DM, with a mean age of 76.5 years, 63.3% women, and a mean of 15.5 years of evolution of T2DM, all managed in the outpatient clinical setting. The primary endpoint was the change in HbA<inf>1c</inf> from baseline to the end of the study. The secondary endpoints included changes in body weight and the proportion of patients achieving HbA<inf>1c</inf> <7.0% and body weight loss >5%. After 12 months of follow-up, the reductions in HbA<inf>1c</inf> were -0.61±0.9% (P<0.0001) in the total cohort. Body weight reductions were -8.2±5.3 kg (P<0.0001). Overall, 67% reached the objective of an HbA<inf>1c</inf> level of <7%, and 73% achieved a weight loss of ≥5%. In routine clinical practice in Spain, the use of semaglutide once a week was associated with statistically significant and clinically relevant improvements in HbA<inf>1c</inf> and body weight in adults aged over 70 years with T2DM, without notable adverse effects, which supports real-world use.

Effect of carbohydrate source in a higher protein diet on body weight, body composition, and metabolic health outcomes in adults at risk for type 2 diabetes

Objective: The objective of this study was to determine the impact of carbohydrate source in higher protein diets on body composition and markers of metabolic health in adults at risk for type 2 diabetes. We hypothesized that carbohydrate source would not impact body composition or markers of metabolic health. Methods: Male and female participants between the ages of 25 and 50 years old were recruited to participate in this 16 week, randomized, controlled, parallel design study (n=21; 14 females and 7 males; age 35.5 ± 10.5). To qualify participants had meet the following criteria: two or more characteristics of metabolic syndrome (body mass index (BMI) &gt; 25, abdominal obesity, triglyceride level over 150 mg/dl, HDL cholesterol &lt; 40 mg/dl in men and 50 mg/dl in women, systolic blood pressure of 130 mm Hg or diastolic blood pressure of 85 mm Hg, and/or fasting glucose &gt; 100 mg/dL) and were consented to participate in this study. Participants were randomized to one of two treatments groups: 1) higher protein diet containing white potatoes (WP; n=11) or 2) higher protein diet with starch carbohydrate (SC; n=10). All diets were isoenergetic within individual participants. Energy content for weight maintenance per individual was calculated using the Harris Benedict equation x 1.35. Each participant was instructed to follow a macronutrient ratio of 30% protein, 30% fat, and 40% carbohydrates. Body composition was measured via DXA at baseline and 16 weeks. Biomarkers of metabolic health were measured at baseline, 4, 8, 12, and 16 weeks. Ethical approval for this study was obtained from the Office of Research Compliance Institutional Review Board of the University of Arkansas (Fayetteville, AR). This study was registered at clinicaltrials.gov (NCT03935048). Written consent was obtained from all participants prior to beginning the study. Results: There was no effect of carbohydrate source on fasting total cholesterol, HDL cholesterol, LDL cholesterol, triglycerides, glucose, or blood pressure after 16 weeks of dietary intervention. There was a significant effect of time and diet (p&lt;0.05) on body weight (WP:-2.06±4.62; SC: +2.90±6.20 lbs) and an effect of diet on (p&lt;0.05) on BMI (WP: -0.39±0.74; SC: 0.42±1.06). Participants following SC had increased loss of fat mass and an increase in fat-free mass compared to WP, but this change was not significantly different. Conclusion: Preliminary data suggests that carbohydrate source in a higher protein diet may influence body composition with no effect on biomarkers of metabolic health. Alliance for Potato Research and Education This is the full abstract presented at the American Physiology Summit 2023 meeting and is only available in HTML format. There are no additional versions or additional content available for this abstract. Physiology was not involved in the peer review process.

Nutrition Intervention for Undernourished Older Adults amid the COVID-19 Pandemic

Background: Older adults are vulnerable to disease exposure because of the agerelated decrease in immune capacity. Older adults with macronutrient and micronutrient deficiencies may have poor nutritional status and low immune responses, making them prone to COVID-19 infection. Objective: This study aimed to assess the effect of orange almond potato cookie supplementation on weight, hemoglobin, and albumin levels in undernourished older adults during the COVID-19 pandemic. Methods: A quasi-experimental study design was utilized in a cohort of 31 older adults. The subjects consumed 50 grams of cookies per day for 4 weeks. The examination was performed to assess the hemoglobin and albumin levels at pre- and post-study timepoints. Education about balanced nutrition and anemia was provided throughout the study using leaflets, flipcharts, and videos. The subjects were weighed weekly to assess compliance; cookies were distributed, and a daily food consumption record was collected three times a week during home visits. Results: Weight, hemoglobin, and albumin levels increased by 0.4 kg, 0.1 points, and 1 point, respectively. The difference was significant for weight, albeit nonsignificant for hemoglobin and albumin levels. At the end of the study, participants’ knowledge regarding balanced nutrition and anemia was statistically significantly different, as well as that of energy, carbohydrate, protein, fat, vitamin C, and iron intake. Weight gain was found to be influenced by the total cookie consumption (p &lt; 0.035). Conclusion: Orange almond potato cookies increased the undernourished older adults’ weight when consumed for 4 weeks.

Additional effects of exercise to hypocaloric diet on body weight, body composition, glycaemic control and cardio-respiratory fitness in adults with overweight or obesity and type 2 diabetes: A systematic review and meta-analysis.

This systematic review and meta-analysis evaluates the additional effect of exercise to hypocaloric diet on body weight, body composition, glycaemic control and cardio-respiratory fitness in adults with overweight or obesity and type 2 diabetes. Embase, Medline, Web of Science and Cochrane Central databases were evaluated, and 11 studies were included. Random-effects meta-analysis was performed on body weight and measures of body composition and glycaemic control, to compare the effect of hypocaloric diet plus exercise with hypocaloric diet alone. Exercise interventions consisted of walking or jogging, cycle ergometer training, football training or resistance training and duration varied from 2 to 52 weeks. Body weight and measures of body composition and glycaemic control decreased during both the combined intervention and hypocaloric diet alone. Mean difference in change of body weight (-0.77 kg [95% CI: -2.03; 0.50]), BMI (-0.34 kg/m2 [95% CI: -0.73; 0.05]), waist circumference (-1.42 cm [95% CI: -3.84; 1.00]), fat-free mass (-0.18 kg [95% CI: -0.52; 0.17]), fat mass (-1.61 kg [95% CI: -4.42; 1.19]), fasting glucose (+0.14 mmol/L [95% CI: -0.02; 0.30]), HbA1c (-1 mmol/mol [95% CI: -3; 1], -0.1% [95% CI: -0.2; 0.1]) and HOMA-IR (+0.01 [95% CI: -0.40; 0.42]) was not statistically different between the combined intervention and hypocaloric diet alone. Two studies reported VO2max and showed significant increases upon the addition of exercise to hypocaloric diet. Based on limited data, we did not find additional effects of exercise to hypocaloric diet in adults with overweight or obesity and type 2 diabetes on body weight, body composition or glycaemic control, while cardio-respiratory fitness improved.

Birth weight and subclinical cardiovascular and renal damage in a population-based study (the STANISLAS cohort study).

Although preterm-born and low-birth-weight individuals have an increased risk of cardiovascular diseases in adulthood, little is known regarding early cardiovascular and renal damage (CVRD) or hypertension in adulthood. Our study investigated the association of birth weight with early CVRD markers as well as the heritability of birth weight in an initially healthy family-based cohort. This study was based on 1028 individuals from the familial longitudinal STANISLAS cohort (399 parents/629 children) initiated in 1993-1995, with a fourth examination conducted in 2011-2016. Analyses performed at the fourth visit included pulse-wave velocity, central pressure, ambulatory blood pressure, hypertension status, diastolic dysfunction/distensibility, left ventricular mass indexed (LVMI), carotid intima-media thickness and kidney damage. The family structure of the cohort allowed birth weight heritability estimation. Mean (±SD) birth weight was 3.3 ± 0.6 kg. Heritability was moderate (42-44%). At the fourth visit, individuals were 37 years old (32.0-57.0), 56% were women and 13% had antihypertensive treatment. Birth weight was strongly and negatively associated with hypertension [odds ratio (OR) 95% confidence interval (CI) 0.61 (0.45-0.84)]. A nonlinear association was found with LVMI, participants with a birth weight greater than 3 kg having a higher LVMI. A positive association ( β 95% CI 5.09 (1.8-8.38)] was also observed between birth weight and distensibility for adults with normal BMI. No associations were found with other CVRD. In this middle-aged population, birth weight was strongly and negatively associated with hypertension, and positively associated with distensibility in adults with normal BMI and with LVMI for higher birth weights. No associations were found with other CVRD markers.

Intake of hot water after each meal as a weight reduction strategy – a prospective randomized controlled trial

Introduction and Aim: Intake of water before meal is associated with weight loss. There is a paucity of literature with comparative evaluation of taking warm water or regular water after meals on weight and BMI. Hence, we designed a randomized controlled trial with regular and warm water after meals to investigate the comparative efficacy of warm and regular water intake after meals on weight and BMI in overweight adults. Methodology: Fifty participants were randomized into two groups, with Group H instructed to drink 200-250 ml of warm water after each meal and Group C to drink the same amount of regular water. Results: The demographic data prior to the study in both the groups were similar. Compliance was high in both groups, and after three months, the warm water group experienced a significant reduction in weight and BMI compared to the regular water group (p=0.000). In Group H, weight and BMI came down from 76 to 73 and 29 to 27 respectively. Conclusion: The study concluded that warm water intake after meals may contribute to weight loss without major side effects. This is the first attempt to investigate the influence of warm water on weight reduction.

Effects of resistance training on body weight and body composition in older adults: An inter-individual response difference meta-analysis of randomized controlled trials.

Whether true inter-individual response differences (IIRD) occur as a result of resistance training on body weight and body composition in older adults with overweight and obesity is not known. To address this gap, data from a previous meta-analysis representing 587 men and women (333 resistance training, 254 control) ≥ 60 years of age nested in 15 randomized controlled trials of resistance training ≥ 8 weeks were included. Resistance training and control group change outcome standard deviations treated as point estimates for body weight and body composition (percent body fat, fat mass, body mass index in kg.m2, and lean body mass) were used to calculate true IIRD from each study. True IIRD as well as traditional pairwise comparisons were pooled using the inverse-variance (IVhet) model. Both 95% confidence intervals (CI) and prediction intervals (PI) were calculated. While statistically significant improvements were found for body weight and all body composition outcomes (p < 0.05 for all), no statistically significant IIRD was observed for any of the outcomes (p > 0.05 for all) and all 95% PIs overlapped. Conclusions: While resistance training is associated with improvements in body weight and body composition in older adults, the lack of true IIRD suggests that factors other than training response variation (random variation, physiological responses associated with behavioral changes that are not the result of resistance training) are responsible for the observed variation in body weight and body composition.

Overweight in Older Adults: A Follow-Up of Fifteen Years of the SABE Survey

Despite extensive research on overweight and obesity, there are few studies that present longitudinal statistical analyses among non-institutionalized older adults, particularly in low- and middle-income countries. This study aimed to assess the prevalence and factors associated with excess weight in older adults from the same cohort over a period of fifteen years. A total of 264 subjects aged (≥60 years) from the SABE survey (Health, Wellbeing and Aging) in the years 2000, 2006, 2010, and 2015 in the city of São Paulo, Brazil, were evaluated. Overweight was assessed by a BMI of ≥28 kg/m2. Multinomial logistic regression models adjusted for sociodemographic and health data were used to assess factors associated with excess weight. After normal weight, overweight was the most prevalent nutritional status in all evaluated periods: 34.02% in 2000 (95%CI: 28.29-40.26); 34.86% in 2006 (95%CI: 28.77-41.49%); 41.38% in 2010 (95%CI: 35.25-47.79); 33.75% in 2015 (95%CI: 28.02-40.01). Being male was negatively associated with being overweight in all years (OR: 0.34 in 2000; OR: 0.36 in 2006; OR: 0.27 in 2010; and OR: 0.43 in 2015). A greater number of chronic diseases and worse functionality were the main factors associated with overweight, regardless of gender, age, marital status, education, physical activity, and alcohol or tobacco consumption. Older adults with overweight and obesity, a greater number of chronic diseases, and difficulties in carrying out daily tasks required a greater commitment to healthcare. Health services must be prepared to accommodate this rapidly growing population in low- and middle-income countries.

Study on the relationship between indexes of different abnormal weight and dyslipidemia in adults in Beijing City

Objective: To analyze the relationship and consistency between indexes of different abnormal weight and dyslipidemia in adults in Beijing City. Methods: From August to December of 2017, 4 975 residents aged 18 to 79 years old in 5 districts of Beijing were randomly selected as subjects by using a multi-stage stratified cluster sampling method. Questionnaire, physical examination and laboratory tests were conducted. The prevalence of overweight/obesity, high body fat rate, central obesity, and high waist-to-height ratio was calculated. Partial correlation was used to analyze the correlation of blood lipid with body mass index (BMI), body fat rate, waist circumference and waist-height ratio. Logistic regression analysis for complex sampling was used to analyze the relationship between indexes of different abnormal weight and dyslipidemia after controlling for relevant risk factors, including age, sex, smoking status, drinking, insufficiency intake of vegetable and fruit, physical inactivity. Kappa value was computed to analyze the consistency between indexes of different abnormal weight. Results: The weighted prevalence of dyslipidemia was 30.48%, and it was higher in men than that in women (40.16% vs. 20.52%, P<0.01). The weighted rate of overweight/obesity, high body fat rate, central obesity, and high waist-to-height ratio was 56.65%, 47.52%, 42.48% and 59.45%, respectively. BMI, body fat rate, waist circumference and waist-to-height ratio were positively correlated with the level of total cholesterol, triglyceride, low-density lipoprotein cholesterol, and non-high-density lipoprotein cholesterol, and negatively correlated with high-density lipoprotein cholesterol. Logistic regression analysis for complex sampling showed that the high body fat rate (OR=1.67, 95%CI: 1.35-2.07), overweight/obesity (OR=1.65, 95%CI: 1.26-2.14) and high waist-to-height ratio (OR=1.46, 95%CI: 1.09-1.96) were associated with dyslipidemias. Kappa values of high body fat rate with overweight/obesity, high waist-to-height ratio and central obesity were 0.65, 0.53 and 0.58, respectively (P<0.05). Conclusion: In 2017, the prevalence of dyslipidemia in adults in Beijing City is high, especially in men. Overweight/obesity, high body fat rate and high waist-to-height ratio are associated with dyslipidemia. The high body fat rate is most associated with dyslipidemia.

Intention to lose weight and depressive symptoms in healthy young Hispanic adults: an online survey

Intention to lose weight and depressive symptoms in healthy young Hispanic adults: an online survey