Weight Discrepancy Research Articles

The role of actual-ideal weight discrepancy in the relationships between perfectionism, self-esteem, self-compassion and eating pathology in adolescents with eating disorders

Understanding factors associated with adolescent eating disorders is important for improving treatment outcomes. Actual-ideal weight discrepancy refers to the discrepancy between actual weight and the ideal weight an individual wants to achieve. Actual-ideal weight discrepancy is associated with poorer treatment outcome in eating disorders. It is important to understand factors associated with weight discrepancy to identify targets for treatment to improve outcomes. The aim of this study was to examine self-related constructs associated with actual-ideal weight discrepancy. The specific aim was to determine if perfectionism, self-esteem, and self-compassion contribute to eating disorder symptoms in adolescents, both independently, and through the mediating pathway of actual-ideal weight discrepancy. Participants comprised 114 female adolescents, aged 12–17 years with an eating disorder (40% anorexia nervosa, 33% atypical anorexia nervosa, 16% bulimia nervosa, 5% other specified and 5% unspecified feeding and eating disorders). Higher actual-ideal weight discrepancy, higher perfectionism, lower self-esteem, and lower self-compassion were associated with greater eating disorder symptoms. When the predictors of perfectionism, self-esteem, and self-compassion were included together in a path model predicting eating disorder symptoms, the model explained 59% of variance, and self-esteem and actual-ideal weight discrepancy were the only significant predictors of eating disorder symptoms. Lower self-esteem predicted greater eating disorder symptoms directly and through the mediator of actual-ideal weight discrepancy.

Shifting work competencies in an emerging economy: a comparison of accounting students’ perceptions of demand and supply

PurposeThe purpose of this study is to ascertain which competences are seen by employers as important for accounting students in an emerging economy, to triangulate this list with the experiences of working students and compare with those work competencies acquired during the period of study.Design/methodology/approachThis study employs a novel mixed-method approach, with interviews of employers (n = 11) to identify key work competencies, and then with a quantitative study of working students (n = 184) to examine the work competency gap, using paired T-tests and mean weight discrepancy scores. The study was undertaken between September and December 2022.FindingsThe paper provides empirical insights into key work competencies in an emerging economy. There is a focus on technical skills at the university, whilst soft skills are preferred by employers. New key work competencies were uncovered relating to intuition, innovation and communicating in a foreign language. The key personal characteristics required for the job relate to change and uncertainty.Research limitations/implicationsA qualitative assessment of key work competencies of employers and the use of mean weighted discrepancy scores is recommended in further studies in this field.Practical implicationsPractical approaches for educators, government and employers are offered to address the increasing demand for soft skills and other work competencies specific to an emerging economy.Originality/valueThe study is set in an emerging economy, which is underdeveloped in this field. The findings inform key stakeholders with a vested interest in reducing the work competency gap.

Ideal Weight and Weight Discrepancy: A Study of Life Course Trajectories and Intercohort Change in the Netherlands.

Objective: This study examined how individuals' ideal weight and weight discrepancy (between ideal and actual weight) changed over the life course and across cohorts. Methods: The study used population-representative longitudinal data collected in the Netherlands (N = 61,431 observations between 2007 and 2018 among N = 13,409 individuals aged 16 to 80 and born 1927-2000). Results: Ideal weight increased linearly with age. Weight discrepancy showed a bell-shaped age pattern. Approximately half of the age-related increase in ideal weight was associated with concurrent increases in actual weight. Ideal weight and weight discrepancy increased slightly across cohorts. The cohort-related increase in ideal weight vanished after adjusting for change in actual weight. Analyses of population heterogeneity showed similar patterns of change in both outcomes across groups, although levels differed by gender, education, and migration status even after adjusting for differences in actual weight between these groups. Conclusion: These results show that ideal weight and weight discrepancy in the Netherlands change substantially with age and modestly across cohorts. Potential explanations include changes in physical appearance and in the importance of physical appearance.

Assessment of Extension Workers’ Nutrition Education Competency Level and Training Needs in Katsina State, Nigeria

This research was carried out to assess the extension workers’ nutrition education competency level and training needs in Katsina state, Nigeria. A multistage sampling technique was used to sample 90 extension workers from the three agricultural zones in the state. Seven categories of 49 specific nutrition education competency items were adapted for the study. A structured questionnaire was used to collect data from the sampled respondents. The mean competency rating for each competency item was computed using SPSS and Microsoft Excel. A Mean scale to interpret the computed mean values. While mean weight discrepancy score was used to determine the areas of training needed by the extension workers. The findings showed that 85.6% of the respondents were males with a mean age of 44 years. It also revealed that the extension workers had a high level of literacy and vast years of working experience of 20-25 years. In terms of their nutrition education competency level, the findings showed that 71.42% of the extension workers have an average competency level on basic nutrition knowledge, nutritional needs of different household members, Hygiene and sanitation, Post-harvest handling and food safety, as well as on Gender and nutrition. However, the extension workers were found to have a low competency level in planning and resource allocation for household food security which also featured to be the prioritized area of training needed by the extension workers. It was finally recommended that nutrition education should be integrated into the extension worker's professional training in the study area.

Validating Recorded EHR and Actual Weight: Single Institution Study

Abstract Introduction/Objective Our hemapheresis clinic performs outpatient and inpatient therapeutic apheresis procedures including red blood cell exchange and therapeutic plasma exchange. Accurate height, weight, and hematocrit are required for calculating replacement fluid volumes for both procedures. Our practice has been using the patient’s most recent weight recorded in the EHR. The purpose of this quality improvement project is to validate concordance between patients’ actual body weight and documented body weight. Methods/Case Report STUDY DESIGN AND DATA COLLECTION We performed this quality improvement project in our hemapheresis clinic. The study focused on weight variations impacting calculations for apheresis volume requirements. Data were collected from March 20th, 2023 – April 20th, 2023. Patients receiving red blood cell exchange or therapeutic plasma exchange were randomly selected and weighed prior to the procedure on a calibrated scale. The most recently recorded weight in the EHR was also collected. Non-ambulatory patients or patients receiving phlebotomy or stem cell collection were excluded from the study. Statistical Analysis: Statistical analyses were performed using R Statistical Software (Foundation for Statistical Computing, Vienna, Austria). We compared means of two observations using a paired t-test. P values less than 0.05 were considered to be statistically significant to test null hypothesis. Results (if a Case Study enter NA) A total of 40 patient data were collected. Seventeen male and 23 female patients were weighed and recorded. The mean value of EHR weight is 70.56kg and that of clinic weight is 71.41kg (P=0.08701). The weight discrepancy was calculated in comparison with EHR recorded weight and it was transformed to weight discrepancy by percentage using d(clinic weight -EHR weight)/clinic weight*100. Out of 40 patients, 33 patients had weight discrepancy by percentage between 0 to 4%. Conclusion Patient body weight is an important factor in calculating the replacement volume requirements in therapeutic apheresis. It is often prescribed based on the recorded EHR weight. In our data, we have shown that the weight discrepancy is not significant and therefore EHR recorded weight is reliable in replacement volume calculation. Our study is subject to several limitations that it was conducted for one month in a single institution and the sample size is not large. However, our study is novel in describing the relationship between recorded patient data and the actual patient data.

Superior Outcome of Bone Marrow Transplantation Using Fludarabine and Cyclophosphamide with ATG over Fludarabine and Cyclophosphamide without ATG Conditioning Regimen in Severe Aplastic Anemia

ABSTRACT Background: Matched sibling donor (MSD) allogenic hematopoietic stem cell transplantation (allo-HSCT) is the standard of care as the first line therapy for young fit patients with severe aplastic anemia (SAA). There are several conditioning regimens that have been evaluated and used for these patients. Fludarabine (Flu)/cyclophosphamide (Cy)/antithymocyte globulin (ATG) or Cy/ATG led to the best survival. The 5-year probabilities of survival after Flu/Cy/ATG, Cy/ATG, Cy ± Flu, and Busulfan /Cy were 91% (95% CI, 85-96), 91% (95% CI, 89-94), 80% (95% CI, 73-87), and 84% (95% CI, 75-91) (P = .001), (Bejanyan et al. 2019). Objective: To report the outcome of a homogeneous cohort of SAA patients who received a uniform transplantation conditioning regimen protocol (Flu/Cy/ATG) and compare it with the historical protocol (Flu/Cy) from the same transplant center for the same patients population. Methods: This study is a 10-year retrospective analysis of SAA patients who underwent MSD allo-HSCT at King Faisal Specialist Hospital & Research Centre, Riyadh City, Saudi Arabia during the period from 2013 to 2022. The conditioning regimen was consistent of Fludarabine 150 mg/m 2/Cyclophosphamide 200 mg/kg/ Anti-thymocyte globulin (rabbit) 2.5 mg/kg (Flu/Cy/ATG). Graft-versus-host disease (GVHD) prophylaxis was methotrexate (MTX)/tacrolimus (FK) or methotrexate/cyclosporin (CsA). The outcome was compared with the historical published data of 82 patients with SAA received Flu/Cy conditioning regimen for MSD allo-HSCT, (El Fakih et al. 2021). Results: The study included 28 patients with SAA, 46.2% (n=12) patients were females, paroxysmal nocturnal hemoglobinuria (PNH) clone detected in 57.1% (n=16). Total body irradiation (TBI) was added to the conditioning regimen in 25% (n=7) for patients with heavily blood products transfusion pre-HSCT. A total of twenty-six patients (93%) has fully MSD, while 2 (7%) has matched unrelated donors (MUD). Bone marrow (BM) was the stem cell source in 60.7% while 28.6% received peripheral blood (PB) stem cell and 10.7 % received combined (BM/PB). There were twelve patients with donor-recipient sex mismatch. Major ABO mismatch counted for 17.9% (n=5). The median age at transplantation was 25 ±10.2 years. During the observational period, there was no graft failure (GF) and none of the patients died. At 60 days of HSCT; 61 % (n=17) patients achieved full donor whole blood (WB) chimerism, while 11 (39 %) patients had mixed chimerism. At both 180 days and 365 days of HSCT; 69.2% (n=18) patients had full donor chimerism and 30.8% (n=8) of the patients had mixed donor chimerism. Acute GVHD occurs in five cases (17.9%) and none had developed grade III or IV, notably; 80% of GVHD cases (4/5) received PB or BM/PB stem cell source. Chronic GVHD was observed in six cases (21.7%), 66% (4/6) of them had received PB or PB/BM stem cell source. The use of PB was due to either donor related reasons like recipient-donor weight discrepancy or patient's medical condition to achieve early engraftment. Hemorrhagic cystitis occurred in one case (3.6%), none had sinusoidal obstruction syndrome (SOS). CMV viremia without disease occurs in eleven patients (39 %). The median follow-up time for survivors was 34 months, the 2 years overall survival (OS) was 100%, the 2 years event free survival (EFS) defined with GF, or death was 100% compared with the previous result published (El Fakih et al., 2021) which had showen lower OS and EFS of 87.8% and 82.9% respectively with median follow-up of 100 months, Figure1&2. Table-1 and table-2 summarize the comparison of patient's characteristics and outcome of both regimens (Flu/Cy vs Flu/Cy/ATG). Conclusions: The results of the present study showed better outcomes for SAA patients using Flu/Cy/ATG compared with the previous study (El Fakih et al., 2021). Early MSD allo-HSCT for SAA patients using Flu/Cy/ATG conditioning regimen is associated with a favorable outcome of excellent graft function, low rate GVHD and no GF. BM should be the stem cell source in severe aplastic anemia HSCT procedure. Key Words: Severe Aplastic Anemia, Matched Sibling Donor, Conditioning, Bone Marrow Graft, Flu/Cy/ATG.

A comparison of traditional and developmental measures of weight suppression in residential patients with bulimia nervosa.

Weight suppression (WS) is associated with many eating disorder (ED)-related symptoms. However, traditional calculations of WS do not consider the age or height at which one's highest past weight was reached. Lowe et al. (2022) found that developmental WS (DWS) was associated with a wider variety of ED-related symptoms compared with traditional WS (TWS). This study replicated and extended these findings in a larger sample of individuals with bulimia nervosa (BN) at a residential ED treatment center. Participants were 1051 female patients with BN. We examined the relations between each WS measure and ED symptoms, emotional symptoms, and weight history variables. TWS and DWS showed a similar number of relations with ED-related symptoms. DWS was positively related to behavioral symptoms (e.g., vomiting), and negatively related to cognitive symptoms (e.g., weight/eating concern). TWS was positively related to highest premorbid, highest postmorbid, and lowest postmorbid weights. DWS was also positively related to highest premorbid z-scored body mass index (zBMI), but negatively related to lowest and highest postmorbid zBMI. DWS, relative to TWS, may better capture the psychobiological impact of the weight discrepancy that a measure of WS is meant to reflect. Weight suppression, the difference between an individual's past highest weight and current weight, is significantly related to many ED-related symptoms. This study found that a new weight suppression measure, based on expected weight-for-height during physical development, relates to ED characteristics in a different manner from the traditional measure of weight suppression, showing positive associations with behavioral symptoms and negative associations with cognitive symptoms.

Weighty Matters: A Real-World Comparison of the Handtevy and Broselow Methods of Prehospital Weight Estimation.

The majority of pediatric medications are dosed according to weight and therefore accurate weight assessment is essential. However, this can be difficult in the unpredictable and peripatetic prehospital care setting, and medication errors are common. The Handtevy method and the Broselow tape are two systems designed to guide Emergency Medical Services (EMS) providers in both pediatric patient weight estimation and medication dosing. The accuracy of the Handtevy method of weight estimation as practiced in the field by EMS has not been previously examined. The primary objective of this study was to examine the field performance of the Handtevy method and the Broselow tape with respect to prehospital patient weight estimation. This was a retrospective chart review of trauma and non-trauma patients transported by EMS to the emergency department (ED) of a quaternary care children's hospital from January 1, 2021 through June 30, 2021. Demographic data, ED visit information, prehospital weight estimation, and medication dosing were collected and analyzed. Scale-based weight from the ED was used as the standard for comparison. A total of 509 patients <13 years of age were included in this study. The EMS providers using the Broselow method estimated patient weight to within +/-10% of ED scale weight in 51.3% of patients. When using the Handtevy method, the EMS providers estimated patient weight to within +/-10% of ED scale weight in 43.7% of patients. When comparing the Handtevy versus Broselow method of prehospital weight estimation, there was no significant association between method and categorized weight discrepancy (over, under, or accurate estimates - defined as within 10% of ED scale weight; P = .25) or percent weight discrepancy (P = .75). On average, prehospital weight estimation was 6.33% lower than ED weight with use of the Handtevy method and 6.94% lower with use of the Broselow method. This study demonstrated no statistically significant difference between the use of the Handtevy or Broselow methods with respect to prehospital weight estimation. While further research is necessary, these results suggest similar field performance of the Broselow and Handtevy methods.

Confidence based class weight and embedding discrepancy constraint network for partial domain adaptation

Partial domain adaptation (PDA) is a special domain adaptation task where the label space of the target domain is a subset of the source domain. In this work, we present a novel adversarial PDA method named Confidence Based Class Weight and Embedding Discrepancy Constraint Network (CEN). Specifically, we design a robust weighting scheme that takes sample confidence and class information into account. It can automatically distinguish outlier samples in the source domain and reduce their importance. Besides, we consider the relationship between feature norm and domain shift. We limit the expectation of the feature norms of both domains to an adaptive value. By this means, we can align the feature distributions and help the deep model learn domain-invariant representations. Comprehensive experiments on three domain adaptation datasets Office-31, Office-home, and Visda2017 show that our approach surpasses state-of-the-art methods on various PDA tasks.

An unsupervised dual-regression domain adversarial adaption network for tool wear prediction in multi-working conditions

Intelligent tool wear prediction networks are widely used regarding their great advantages in utilizing big data. Since datas from new working conditions is unlabeled, the network must transfer the wear knowledge learned from other conditions. However, the global marginal distribution discrepancy and local degradation stages variation for different working conditions result in low prediction accuracy or failure of the network. An unsupervised Dual-Regression Domain Adversarial Adaption Network (DR-DAN) is proposed, which mines the global and local consistency of degradation features between different working conditions and realizes the knowledge transfer. The proposed weight discrepancy restriction constructs a feature space for extracting local consistency representation. Furthermore, the predictive consistency loss is proposed to match accurate degradation stages without label supervised. To ensure the stability of adversarial training, Wasserstein distance is employed as the optimization function. Two experiments are carried out to demonstrate that DR-DAN has a better performance than other state-of-the-art methods.

Psychometric properties of a Mandarin Chinese version of the Body Appreciation Scale-2 with residents from Chinese mainland

The current study aimed to translate the Body Appreciation Scale-2 (BAS-2) into Mandarin Chinese and explore its psychometric properties with college students from the Chinese mainland. In Study 1 (N = 840, 415 women, 425 men), an exploratory factor analysis upheld the unidimensional factor structure of the Mandarin Chinese BAS-2, and McDonald’s omega supported the internal consistency reliability of its scores. Evidence of construct validity of the Mandarin Chinese BAS-2 was also accrued via its positive correlations with self-esteem, self-compassion, and body satisfaction as well as negative correlations with BMI, weight discrepancy, negative affect, and body surveillance. Its negative correlation with eating disorder symptomatology and negligible correlation with impression management supported its criterion-related validity and discriminant validity, respectively. Additionally, the Mandarin Chinese BAS-2 contributed unique variance in eating disorder symptomatology and self-esteem beyond the variance explained by BMI and other body satisfaction measures, providing evidence of incremental validity. Study 2 (N = 522, 322 women, 230 men) confirmed its unidimensional factor structure, upheld the internal consistency and stability of its scores over a 3-month period, and supported its measurement invariance between women and men. Taken together, these findings support the cross-cultural validity of the Mandarin Chinese BAS-2 on the Chinse mainland.

Pure laparoscopic versus open right hepatectomy in living liver donors: bench-surgery time and graft weight discrepancy

Kwangpyo Hong, Suk Kyun Hong, Eui Soo Han, Sanggyun Suh, Su young Hong, Jeong-Moo Lee, YoungRok Choi, Nam-Joon Yi, Kwang-Woong Lee, Kyung-Suk Suh. Korean J Transplant 2021;35:142. https://doi.org/10.4285/ATW2021.OP-1170

Are explicit and implicit affective attitudes toward different body shape categories related to the own body-satisfaction in young women? The role of mindfulness, self-compassion and social media activity

Implicit and explicit attitudes influence our behavior. Accordingly, it was the main goal of the paper to investigate if those attitudes are related to body image satisfaction. 134 young women between 18 and 34 years completed an explicit affective rating and an implicit affective priming task with pictures of women with different BMIs. Because it is well known that mindfulness, self-compassion and social media activity influence body image satisfaction, these variables were registered as well. The results confirmed an explicit positive affective bias toward pictures of slim women and a negative bias toward emaciated and obese body pictures. It adds to the literature that the explicit positive bias does not hold true for the strongest form of underweight, suggesting that instead of dividing different body shapes into two groups, different gradings of under- and overweight should be considered. Concerning the affective priming task, no significant differences between the different pictures could be carved out. Implicit and explicit affective attitudes were not related to the body satisfaction of the participating women. In line with former studies, body satisfaction was predicted by the actual-ideal weight discrepancy, the BMI, aspects of mindfulness and self-compassion. This study indicates that implicit and explicit affective attitudes toward underweight and overweight women are unrelated to the participants’ body satisfaction.

Psychometric properties of a Romanian translation of the Functionality Appreciation Scale (FAS)

The Functionality Appreciation Scale (FAS; Alleva et al., 2017) is a 7-item measure of an individual’s appreciation of their body for what it can do and is capable of doing. Although the instrument is increasingly used in interventionist studies, its psychometric properties have been infrequently investigated outside Anglophone populations. Here, we examined psychometric properties of a novel Romanian translation of the FAS. An online sample of 959 Romanian adults (18–73 years old) completed the Romanian FAS, and validated measures of positive body image (body appreciation), negative body image (weight discrepancy in women, drive for muscularity in men), eating disorder symptomatology, and psychological well-being (self-esteem, gratitude). Exploratory factor analyses led to the extraction of a 1-dimensional model of FAS scores, which we confirmed using confirmatory factor analysis. FAS scores achieved scalar invariance across sex, but the sex difference in latent FAS scores did not reach significance (d = 0.15). FAS scores had adequate internal consistency and test-retest reliability up to four weeks, and further analyses provided evidence of convergent, construct, and incremental validity. These results support the psychometric properties of the Romanian FAS and present evidence of the importance of functionality appreciation in relation to healthier body image and psychological well-being.

Development and evaluation of image-series for portion size estimation in dietary assessment among adults.

Portion size images are advantageous in dietary assessment. The aim of the present study was to develop and validate new culturally specific image-series for portion size estimation to be used in a new Norwegian version of a British web-based dietary assessment tool (myfood24). Twenty-three image-series of different foods, each containing seven portion size images, were created and validated in a group of adults (n 41, 58 % female) aged 19-44 (median 23), out of which 63 % had higher (tertiary) education. The participants compared 46 portions of pre-weighed foods to the portion size images (1886 comparisons in total). Portion size estimations were either classified as correct, adjacent or misclassified. The weight discrepancy in percentage between the chosen and the correct portion size image was also calculated. Mann-Whitney U tests were used to explore if portion size estimation accuracy differed across sample characteristics, or if it depended on how the foods were presented. For thirty-eight of the forty-six presented food items, the participants selected the correct or adjacent portion size image 98 % on average. The remaining eight food items were on average misclassified by 27 % of the participants. Overall, a mean weight discrepancy of 2⋅5 % was observed between the chosen and the correct portion size images. Females estimated portion size more accurately than males (P = 0⋅019). No other significant differences in estimation accuracy were observed. In conclusion, the new image-series performed satisfactorily, except for the image-series depicting bread, caviar spread and marzipan cake, which will be altered. The present study demonstrates the importance of validating portion size estimation tools.

In-Service Agricultural Mechanics Needs of Montana Mid-Career Agricultural Educators

Agricultural mechanics—a pillar of many secondary agricultural education programs—is a dynamic, constantly changing field, requiring educators to continually evolve their programs to maintain relevance. This study explored the in-service agricultural mechanics needs of Montana mid-career agricultural educators. We used mean weighted discrepancy scores and descriptive measures to analyze demographics and perceived levels of importance and competency to teach agricultural mechanics content areas. The areas of highest perceived importance of teaching were welding safety, mechanical safety, and construction and shop safety. The areas that educators felt least competent to teach were differential leveling, profile leveling, and cleaning motors. Mean weight discrepancy scores revealed the greatest discrepancies between importance and competence to teach in the areas of electrical safety, computer aided design, and differential leveling. Agricultural educator associations and industry experts should collaborate with advisory groups, local businesses, and organizations such as the Chamber of Commerce to determine the relevance of low-ranking content areas and create professional development opportunities for educators in these areas.

Body image, weight discrepancy and body mass index among university students in Riyadh, Saudi Arabia

Body image, weight discrepancy and body mass index among university students in Riyadh, Saudi Arabia

Fused placentas: Till birth do us part

Twinning and placental fusion occur at a low frequency in species like humans and mice. They are linked to reduced birth weight and intertwin growth discrepancy with important consequences for perinatal survival. Despite this, little is known about the histological characteristics of the twin or fused placenta and how these relate to fetal growth. In this case report, we characterise the histological changes of a fused mouse placenta showing intertwin growth discrepancy. Our study demonstrates that morphological changes in the placental exchange and endocrine regions and elevated calcification levels may contribute to the intertwin growth discrepancy observed in mouse pregnancy.

Hematopoietic Stem Cell Transplant (HSCT) Utilizing Reduced Intensity Conditioning without Radiation Is an Effective Treatment for Children with Sickle Cell Disease Using Alternative Donors

Sickle cell disease can be cured with allogeneic HSCT. However, graft rejection and treatment related morbidity remains an obstacle in treating these patients with HSCT. Consequently, the intensity of the preparative regimen is crucial in establishing a balance between low treatment related morbidity and durable engraftment. <b>Methods and Materials:</b> This is a single center retrospective analysis of pediatric HSCT recipients that received non-radiation containing reduced intensity conditioning from September, 2016, to present. The patients were all conditioned with distal alemtuzumab (d-23 thru d-20), fludarabine (d-7 thru d-2), thiotepa (d-3) and melphalan (d-2). GvHD prophylaxis consisted of MMF and tacrolimus for all patients. Haploidentical transplants received posttransplant cyclophosphamide, and mismatched sibling donors received prednisone. Bone marrow was the preferred graft source. G-CSF was given to donors with a significant weight discrepancy to recipient. <b>Results:</b> Three patients with sickle cell disease received this non-radiation containing reduced intensity regimen utilizing distal alemtuzumab. Neutrophil and platelet engraftment were timely. No life threatening complications were incurred posttransplant. Acute GvHD (grade I skin) occurred in one patient, and there has been no chronic GvHD in 2 evaluable patients. Donor engraftment has been 100% in whole blood and CD3+ compartments in all 3 patients. All 3 patients remain transfusion free with serum hemoglobin near normal range. <b>Conclusion:</b> Reduced intensity conditioning utilizing distal alemtuzumab and no radiation results in durable engraftment with no significant GvHD in this small number of patients with sickle cell disease with complications. Risk of viral reactivation, especially CMV, remains high in patients receiving alemtuzumab containing conditioning.

Prevalence and correlates of eating disorders in greek-cypriot adolescents and young adults

The present study aimed to explore the prevalence rates of eating disorders among Greek-Cypriot adolescents and young adults and examine the role of the following variables in relation to eating disorder risk: gender, age, dieting, exercise and present-ideal weight discrepancy. One thousand and eighty-one middle, high school and university students responded to self-reported measures assessing eating disorders, weight-related concerns and behaviors. Prevalence estimates were 26% for high eating disorder risk and 14.98% for subthreshold eating disorders symptoms while 12% of participants met criteria of an eating disorder diagnosis. Multivariate logistic regression confirmed well-established predictors for eating disorder risk including present to ideal weight discrepancy which had a differential effect on risk in adolescents (i.e., 6-10 kg) and young adults (11+kg). This is the first study to provide prevalence rates of the entire eating pathology spectrum among Greek-Cypriot youth. Results are discussed in terms of their implications in the development of age-specific screening tools and prevention programs.