Weeks Of Amenorrhea Research Articles

Feasibility of Scanopelvimetry in the Medical Imaging Department of the University Hospital of Point “G”.

Purpose: The purpose of our study was to describe the technique of scanopelvimetry used in the radiology department of the Point G University Hospital, to specify the indications of scanopelvimetry in the department and to evaluate the cost of radiopelvimetry. Patients and Method: This was a prospective, cross-sectional study that took place over a 12-month period from January 1 to December 31, 2018. It focused on pregnant women in whom scanopelvimetry was performed in the medical imaging department of Point G University Hospital during the study period. Results: Out of 8615 CT examinations performed in the radiology department, we collected 65 cases of scanopelvimetry, i.e., 0.7% of the CT examinations. Primigravida and paucigravida dominated the study (40% each). In 60% of the pregnant women the height was less than 150 cm. The most frequent indication for CT scanning was clinical pelvic narrowing (50%). In 80% of the cases, the scanopelvimetry was performed after 37 weeks of amenorrhea. A predominance of narrowing of the superior strait was noted (40%). 4.6% of the pregnant women had a Magnin index of less than 20. CT scanopelvimetry is a feasible examination in our context but the level of demand is low because of the high cost of the examination (49500 fca). Conclusion: In light of the results obtained, we can say that CT pelvimetry allows us to predict the probable route of delivery and thus we can reduce the risk of fetomaternal morbidity and mortality to improve maternal and child health.

Factors associated with post-term pregnancy at the Yalgado Ouédraogo University Hospital: case-control study

post-term pregnancy is a risky situation for the fetus and the mother. In our context, few data exist on the subject. This aims to determine the associated factors of post-term pregnancy in order to contribute to a reduction in maternal and fetal morbidity and mortality. we conducted a matched case-control study in the department of gynaecology-obstetrics of the Yalgado Ouédraogo University Hospital. Data were collected between 1st January 2014 and 31st August 2014. Cases were patients who delivered at 41 weeks of amenorrhoea and above and controls were those who delivered between 37 and 41 weeks of amenorrhoea. the study included 153 cases and 153 controls. Risk factors with statistically significant association with post-term pregnancy were high maternal socioeconomic status (adjusted odds ratio (AOR)=3.17; 95% CI [1.13; 9.07]) primiparity (AOR=1.45; 95% CI [1.07; 2.51]), and previous post-term pregnancy (AOR=7.02; 95% CI [2.08; 23.79]). early recognition of risk factors for post-term pregnancy will help health workers identify women with high-risk pregnancies.

Statural and Weight Growth of Low Birth Weight at 9 Months

Introduction: Low birth weight (LBW) is defined as a birth weight 2500 g at birth, regardless of the term of pregnancy. The objective of this study is to evaluate their stature and weight growth from 0 to 9 months of corrected age (CA) in Senegal. Methodology: This is a prospective, descriptive, and analytical cohort follow-up up to 9 months of CA including all live newborns of LBW hospitalized and followed up from 01 August 2019 to 31 May 2020. World Health Organization growth charts were used to assess stature and weight growth. Results: During the study 136 LBW newborns were included. The mean gestational age was 32 weeks of amenorrhea. At discharge, 46 children (33.82%) were exclusively breastfed. At birth, the mean weight was 1487 g (3rd-10th percentile) and the mean height was 41.52 cm (10th-25th percentile). At 9 months of CA, the mean weight was 8119 g (median) and the mean height was 74 cm (median). The children had achieved satisfactory growth in weight (84%) and height (89%). At 9 months of CA, 27% of the children were behind in one of the four areas of psychomotor development. Conclusion: At the end of 9 months of CA, stature and weighted growth was normal.

Umbilical cord hemangioma diagnosed at 31 weeks of amenorrhea: A rare case report

Umbilical cord hemangioma is a rare benign vascular tumor, not always detected prenatally, several fetal complications can occur such as fetal prematurity, intra uterine growth restriction, fetal malformations, intra uterine death. We describe a case of Umbilical cord hemangioma diagnosed at 31 weeks of amenorrhea complicated with an intra-uterine growth restriction and preterm delivery at 31 weeks of amenorrhea with good maternal and fetal outcome. We reviewed the literature data.

Tuberculous peritonitis during pregnancy: Case report

Introduction: Tuberculous Peritonitis (TP) in pregnancy is a rare condition, and the diagnosis can be deleyed because of the symptoms non specificity. Case report: 31-year-old parturient primigravidia at 34 weeks of amenorrhea presented diffuse and intense abdominal pain with vomiting. Examination found abdominal distention with ascites. Investigations did not lead to a precise diagnosis, therefore, an exploration by laporotomy with cesarean delivery were performed. The diagnosis of Tuberculous peritonitis on histopathologic examination was confirmed. Discussion: Tuberculous peritonitisis extremely rare in pregnancy, and the rate of TP among all forms of tuberculosis varies from 0.1% to 0.7% worldwide. Gold standards for the diagnosis of TP are the identification of M. tuberculosis in ascites and peritoneal biopsy findings compatible with tuberculosis. Bacteriologic examination of the biopsy specimen should be performed, because this could be positive for tuberculosis when histological examination is negative. Conclusion: The early diagnosis and treatment of TP in pregnancy are important to prevent obstetric and neonatal morbidities. Keywords: tuberculous peritinitis; pregnancy; rare; delayed diagnosis.

Prolonged pregnancy, incidence and morbidity

Abstract Background The classic term for a pregnancy is between 37 and 42 weeks of amenorrhea. In fact, the literature has shown that exceeding the term (LD, 42WG) is the cause of many maternal-fetal complications despite close monitoring and appropriate management. A new rigorous and adapted management is essential in view of the materno-fetal prognosis. Objectives To describe the complications and risks associated with exceeded pregnancies and to propose a new strategy indicating an appropriate course of action. Patients and Methods This is a retrospective study of 50 women who gave birth at 42 WG or more at the Maternity of the Farhat Hached University Hospital Center in Sousse. Results the average age of our patients was 30.56 years old, 70% of which were primiparous, 82% of our patients were monitored between 41 and 42 WG. Fetal complications demonstrated in our results were increased by macrosomia in 54% of cases, pathological FHR during labor in 48% of cases, fetal distress in 26% of cases. In addition, maternal complications were increased by cesarean delivery in 48% of cases, perineal tears in 40% of cases and forceps delivery in 20% of cases. Conclusions By comparing the expectation under supervision to induction of labour at 41WG, we concluded that induction of labour reduces maternal-fetal outcomes in a remarkable way. A new management including systematic induction of labour at 41 WG is essential to prevent complications and guarantee a reassuring maternal-fetal prognosis. Key messages Exceeding the classic term for a pregnancy may cause maternal and fetal complications. A new management including systematic induction of labour at 41 WG is essential to prevent complications and guarantee a reassuring maternal-fetal prognosis.

Prenatal diagnosis of complete atrioventricular canal

The atrioventricular duct is a complex heart defect. These anomalies represent 4% of congenital heart disease. The prevalence varies between 0.24/1000 to 0.31/1000 of births. It is the heart disease whose relationship to chromosomal abnormalities is the strongest, particularly the trisomy 21, which is associated in more than 20% of cases. Twenty-six years old, gravida2para 2, a living child. The first trimester ultrasound without abnormalities. A morphological ultrasound discovered a complex heart disease associating a complete CAV with almost single atrium and leakage of the atrioventricular valve. The karyotype is that of a trisomy 21. The therapeutic interruption of the pregnancy was refused with term delivery by vaginal route. The baby died at day 3 of life. Thirty-three years old G1P1, the ultrasound of the first trimester is without abnormality. On morphological echography: bilateral pyelic hypotonia, complex cardiac malformation of unbalanced CAV type in favor of the right side. The karyotype reveals a trisomy 21. The patient had a medical interruption of the pregnancy. Twenty-three years old, G1P1, pregnancy not followed. The first consultation at 33 weeks of amenorrhea, on ultrasound: biometric consistent with the term, aspect of complex heart disease with single ventricle, malposition of the large vessels and pulmonary stenosis. The evolution is marked by vaginal delivery at term. Birth weight 3500 grams. Apgar 8/9 TTE + CT angio on day 1: complete CAV, death on day 11. The atrioventricular duct is frequently associated with a chromosomal abnormality. It can be integrated into certain syndromic association. trisomy 21 being the most frequently found triploidy among them. Trisomy 18, Ellisvan–Creveld syndrome or Pallister–Hall syndrome are also frequently associated. The prognosis depends on the type of CAV, the presence of aneuploidy and the association of extracardiac abnormalities, hence the interest of antenatal screening.

Evaluation of the use of the partogram in the obstetric gynecology department of the National Hospital Donka University Teaching Hospital Conakry Guinea

Objectives: To calculate the proportion of partogram use in the department, to describe the epidemiological profile of parturients, to identify the main reasons for not filling out the partogram and to establish the maternal and fetal prognosis in the gynaecology-obstetrics department of the Donka National Hospital, University Teaching Hospital of Conakry. Methodology: This was a prospective analytical cross-sectional study lasting six (6) months. All patients admitted to the department during the study period with a longitudinal presentation (cephalic, breech), permeable pelvis with a minimum of 28 weeks of gestational age with a live fetus were included in the study. The following were not included in this study: patients admitted for extreme obstetric emergencies (haemorrhagic placenta previa, retro-placental haematoma, uterine rupture, eclampsia....), patients admitted for prophylactic caesarean section; patients with a gestational age of less than 28 weeks of amenorrhoea and all contraindications to vaginal delivery with a live foetus. Word software from the 2007 office pack, Epi DATA3.1 was used for data entry, SSPS 20.0 was used for data analysis and Power Point software for presentation. The Chi-square test was used for the variables and a probability of p<0.05 was obtained in favour of an association between the variables compared. Results: Out of a total of 402 patients, the partogram was opened in only 269 patients, i.e. 67%, while 133 patients, i.e. 33%, did not receive a partogram. The epidemiological profile of the patients was that of women aged 20-24 years (31.3%), a housewife (34.1%), primiparous women (64.2%) and women who had not attended school (39.1%). 13.02% of the partograms were filled in correctly and 86.98% were filled in inadequately. 60% of the partograms were filled in correctly when they were carried out by a doctor, and only 12.8% were carried out by a midwife. Hypokinesia was found to be the most common anomaly, 60.59%, and the majority of patients (96.3%) did not cross the alert line. The reasons given by the staff interviewed for not filling out the patients were: lack of motivation on the part of the providers (25.56%), emergencies and overflowing activities in the delivery room (15.03%). Half of the staff interviewed did not give any reason for not filling out the partogram (50.37%). A previous caesarean section at the last delivery was found in 2.7% of the patients. The proportion of newborns without labour monitoring with a partogram with an APGAR score of less than 7 was 30.8%, compared with 11.2% with labour monitoring with a partogram. More than 2/3 of the births, 79.56%, that took place before the alert line was crossed, against 20.44% of the alert line. The morbidity is 3.7% for births before crossing the alert line against 20% after crossing it. The overall maternal morbidity is 6.5%: It is 5.57% under partogram, and 8.3% without partogram. Fetal mortality is 2.6% for those who gave birth under labour monitoring with partogram, and 3% for those who did not give birth under labour monitoring with partogram. We did not record any maternal deaths. Conclusion: The partogram is an indispensable tool in labour monitoring. We note a better maternal-fetal prognosis in patients who have given birth under partogram monitoring. The improvement of the quality of filling in the partogram would be achieved through the motivation of medical staff and supervision.

Descriptive Study: Compliance of the standards for estimating gestational age during prenatal care in a general hospital in Ecuador.

BACKGROUND: Gestational dating is an important requirement for decision-making during pregnancy; the World Health Organization recommends making the first ultrasound before week 24. Gestational age can also be estimated based on menstrual history. The aim of this study was to describe the rate of compliance of the standards for estimating gestational age in a general hospital in Machala, Ecuador. METHODS: This is an observational, descriptive, cross-sectional study; the universe was the total of pregnant women who attended for prenatal care to Hospital General Machala, El Oro- Ecuador, between April 2017 and March 2020. The entire universe was studied. We collected data for the variables: age, parity, last menstrual period( LMP), menstrual age, early ultrasound, reliable gestational dating. RESULTS: 47.9% of the sample was 18 to 29 years old. 83.33% (195/234) patients complied with the weeks of amenorrhea registry. 75.21% (176/234) of patients complied with the recommendation of an early ultrasound, at 24 weeks or less. 1.28% did not have any method of gestational dating. 64% (n=149) of the sample underwent the first ultrasound until week 20. Of 140 patients who complied with having both gestational dating by reliable LMP and ultrasound, in 31/140 (22.1%) the gestational age given by LMP could not be confirmed with early ultrasound. CONCLUSION: We concluded that gestational dating obtained by weeks of amenorrhea was registered n 83.33% of the patients, this rate qualifies as regular compliance. An early ultrasound was performed, at ≤ 24 weeks, as recommended by WHO, in 75% of the patients, this rate qualifies as poor compliance.

Heterotopic Pregnancy in Natural Conception – A Case Report

Heterotopic gestation is very rare in natural conception but can be common with assisted reproductive techniques; a high index of suspicion can help in timely diagnosis and appropriate intervention. We report a case of heterotopic pregnancy in a 32-year-old woman presented with hemoperitoneum from ruptured right sided tubal pregnancy with live intrauterine gestation at 12 weeks of amenorrhea, diagnosed on clinical and ultrasound examination.

Hematological Characteristics During the Third Trimester of Pregnancy in a Population of Low and High Socio-Economic Levels in Lubumbashi

Background: During pregnancy, many hematologic changes occur to meet the demands of the developing fetus. The objective of this study was to describe the hematological characteristics in the third trimester in a population of low and high socioeconomic levels in Lubumbashi, in relation to the WHO and China reference values. Methodology: A descriptive cross-sectional observational study was carried out in Lubumbashi, among pregnant women received during the third trimester antenatal consultations in apparent good health. A total of 128 pregnant women with a monofetal pregnancy of at least 27 weeks of amenorrhea in apparent good health were selected and divided into two groups of low and high socioeconomic levels. Blood was drawn and analyzed on the CYANHEMATO machine. Results: Hemoglobin (HB) averages were 9.63 ± 1.52 and 11.19 ± 1.07 g / dl respectively in the low and high socioeconomic levels population. The majority of patients in the two populations were in the reference range for red blood cell (RBC) count from 2.75 to 4.64 1012 / l. The average values of hematocrit (HCT), mean corpuscular volume (MCV) and mean corpuscular hemoglobin (MCH) in Lubumbashi were lower than in the China population : 28.39 ± 4.21 versus 32.47 ± 3.46% ; 67.34 ± 9.50 versus 74.38 ± 8.15 fl and 22.96 ± 3.56 versus 25.71 ± 3.23 pg for reference values of 36% ; 90.8 fl and 30.5 pg, respectively. As for the red blood cell distribution width (RDW), it was higher in the low socio-economic level population (16.86 ± 3.40%) than in the high socio-economic level population (14.90 ± 2.25%) with a difference highly significant (p <0.0001). Conclusion: The RBC and RDW were significantly increased in Lubumbashi, while HB. HCT, MCV and MCH were decreased. The mean corpuscular hemoglobin concentration (MCHC) did not present any particularity

The socio-clinical particularities of preeclampsia in a disadvantaged African black environment

Introduction: Pre-eclampsia is one of the major causes of maternal and neonatal morbidity and mortality in the world. The complexity of its etiopathogenesis involves, among other things, age, primi-gravidity, obesity, lack of sensitization to the partner's sperm. Objective: It was to describe the socio-clinical profile of the preeclampsia pregnant woman received in consultation in our service and to compare it with that of a control population. Methodology: We carried out a situational study of prospective descriptive and analytical type during 07 months from 01 November 2018 to May 31, 2019, in the obstetrics and gynecology department of the Laquintinie Hospital in Douala. We recruited in consultation a continuous series of 150 pregnant women including 50 preeclampsia that we matched to 100 non preeclampsia all at a gestational age greater than 20 weeks of amenorrhea. The variables of interest were age, pregnancy, parity, gestational age, marital status and body mass index. The statistical tests were considered significant for a value of p˂0.05. Results: The preeclampsia pregnant woman in our series had a mean age of 27.80±5.80, mostly in the 25-30years, pauci-gravid, nulliparous and obese grade 1 with a gestational age predominantly ≥37 weeks of amenorrhea. This profile was non-exposing and heterogeneous compared to the control group of the same racial strain and to data from the literature. Conclusion: Our preliminary study suggests the existence of certain socio-clinical peculiarities in the preeclampsia pregnant woman in the black African environment.

An Exceptional Case of Uterine Rupture on a Scarred Uterus Discovered Following a Late Abortion

Uterine rupture (UR) is a life-threatening peripartum complication with a high incidence of maternal morbidity and mortality. It is quite common in the third trimester of pregnancy ranging from 1 / 8,000 to 1 / 15,000 pregnancies. Its true incidence in the first trimester is unknown as most of the reports are case reports or small series of cases. We report an exceptional case of uterine rupture at 13 weeks of amenorrhea in a 34-year-old patient with a history of a cesarean delivery 2 years ago, discovered following a late abortion due to persistent bleeding and failure of aspiration. Through this observation we would like to draw the attention of practitioners to this diagnosis, which is often overlooked in the first trimester.

Phototherapy Using a Light-Emitting Fabric (BUBOLight) Device in the Treatment of Newborn Jaundice: Protocol for an Interventional Feasibility and Safety Study.

BackgroundNeonatal jaundice is a common condition occurring in 60%-80% of all healthy-term and late-preterm neonates. In the majority of cases, neonatal jaundice resolves spontaneously and causes no harm; however, in some neonates, significant hyperbilirubinemia can develop and lead to kernicterus jaundice, a serious neurological disease. Phototherapy (PT) is the preferred treatment for jaundice; however, to be effective, PT devices need to have a broad light emission surface to generate no or little heat and to provide an optimal wavelength and light intensity (420-490 nm and ≥30 µW/cm²/nm, respectively).ObjectiveThis study aimed to investigate the feasibility, safety, and level of satisfaction of parents and health care teams with the BUBOlight device, an innovative alternative to conventional hospital PT, in which luminous textiles have been incorporated in a sleeping bag.MethodsThis interventional, exploratory, simple group, nonrandomized, single-center trial will be conducted at Lille Hospital. In total, 10-15 neonates and their parents will be included to obtain evaluable data from 10 parent-neonate pairs. Neonates weighing more than 2500 g at birth and born with ≥37 weeks of amenorrhea that required PT in accordance with the guidelines of the National Institute For Health and Clinical Excellence will receive one 4-hour session of illumination. Total serum bilirubin and transcutaneous bilirubin levels were obtained at the start and 2 hours after the end of PT. Cutaneous and rectal temperatures, heart rate, and oxygen saturation will be measured at the beginning and during PT. The number of subjects is therefore not calculated on the basis of statistical assumptions. We aim to obtain a minimum proportion of 90% (ie, 9 of 10) of the neonates included, who have been able to undergo 4-hour PT without unacceptable and unexpected toxicities. We will calculate the mean, median, quartiles, minimum and maximum values of the quantitative parameters, and the frequency of the qualitative parameters. The rate of patients with no unacceptable and unexpected toxicities (ie, the primary endpoint) will be calculated.ResultsThe first patient is expected to be enrolled at the end of 2020, and clinical investigations are intended for up to June 2021. The final results of this study are expected to be available at the end of 2021.ConclusionsOur findings will provide insights into the safety and feasibility of a new PT device based on light-emitting fabrics for the treatment of newborn jaundice. This new system, if proven effective, will improve the humanization of neonatal care and help avoid mother-child separation.Trial RegistrationClinicalTrials.gov NCT04365998; https://clinicaltrials.gov/ct2/show/NCT04365998International Registered Report Identifier (IRRID)PRR1-10.2196/24808

Phéochromocytomes et paragangliomes pendant la grossesse : à propos de quatre cas et messages clés sur la prise en charge

ObjectifsThe diagnosis of a pheochromocytoma or paraganglioma secreting during pregnancy is a rare and serious situation, involving maternal-fetal prognosis. The purpose of this case series is to discuss the management of these patients. MethodsThis is a retrospective study of cases of pheochromocytoma (n=2) or paraganglioma (n=2) managed during pregnancy between 2013 and 2020 in one center (Lille, France). ResultsWe report four cases of patients with a diagnosis of pheochromocytoma or paraganglioma during pregnancy, at respectively 4, 28, 31 and 34 weeks of amenorrhea (AS). Their pregnancies were affected by a sudden onset of hypertension sometimes associated with headaches, sweating, and palpitations. All patients delivered by Caesarean section after calcium channel blocker impregnation, with a good outcome. Tumor removal took place at a distance from delivery for each patient. ConclusionsThe therapeutic strategy includes antihypertensive treatment with calcium channel blockers or alphablockers and surgical curative treatment linked to gestational age. Multidisciplinary management as well as early diagnosis can improve the maternal-fetal prognosis. The preferred way of delivery is Caesarean section, but vaginal delivery can also be considered. Removal should ideally take place at a distance from the birth. The analysis of these cases has led to the development of a protocol for monitoring and management of parturients with diagnosis of pheochromocytoma or paraganglioma during pregnancy.

PSEUDO UNICORNUATE UTERUS: CLINICAL CASE AND LITERATURE REVIEW

The pseudo unicornuate uterus is a rare uterine malformation resulting from incomplete unilateral Müllerian aplasia and is estimated to occur in about 10-14% of all uterine anomalies. It is the consequence of a developmental arrest of one of Mullers ducts, which results in a normal hemi-uterus and a rudimentary horn with or without a cavity. We present a case that illustrates this pathology: This is Mrs. S. H, 30 years old, without any notable history, G2P2, G1: the first pregnancy was followed normally at the health center and the delivery took place by cesarian section for breech presentation in a primiparous woman at term, G2: The second pregnancy was followed up until 39 weeks of amenorrhea at the health center, admitted in early labor, obstetrical ultrasound revealed a single fetal pregnancy with breech presentation, the indication for extraction by the high route was indicated for breech presentation in a scarred uterus. On exploration we noted the presence of a right hemi-uterus in which the pregnancy had developed with a homolateral horn and adnexa, and a small rudimentary remnant on the left continuing with a tube.

ILEOSIGMOID NODE DURING PREGNANCY: RARE SURGICAL ENTITY

The ileo-sigmoid knot is a rare surgical entity, corresponding to the wrapping of the ileum around the base of the sigmoid colon forming a knot.An associated condition with a rapid progression to intestinal gangrene and high mortality. It is a rare cause of intestinal obstruction and especially during pregnancy. We report here the case of a patient at 13 weeks of amenorrhea with an ileo-sigmoid knot diagnosed at a late stage with fetal loss.

Discovering Rheumatoid Arthritis During Pregnancy

Rheumatoid arthritis is an autoimmune mechanism disease that preferentially affects women. Remission from rheumatoid arthritis has often been associated with pregnancy.
 A 29-year-old woman presented with symmetrical inflammatory polyarthralgias of the large and small joints with morning stiffness estimated at 5 hours, and the Visual Analogue Scale at 80/100 associated with the joint swelling onset 12th week of amenorrhea. She has no medical history, third pregnancy, and no fetal loss has been reported. The physical examination of the day objectified five painful joints and two swollen joints. Disease activity was moderate. There was a biological inflammatory syndrome with a C-Reactive Protein (CRP) at 37.9 mg. Rheumatoid factor was positive at 214 IU (Standard <14 IU), anti-citrullinated peptides antibodies at 99.6 IU (Standard <17 IU).
 The pregnancy revealed rheumatoid arthritis positive to rheumatoid factor and citrullinated cyclic anti-peptide antibodies. 

Epidemioclinical Profile of Premature Infants at the Neonatology Unit of the Mali Hospital 2012-2015

Introduction: A newborn is preterm when it is born before 37 weeks of amenorrhoea. Preterm births account for 11.1% of live births worldwide, 60% of which are in South Asia and sub-Saharan Africa. Preterm birth is the leading cause of neonatal mortality and the second leading cause of mortality in children under 5 years of age. The aim of this study was to investigate prematurity in the neonatology unit of the Mali Hospital. Materials and Methods: This was a cross-sectional, descriptive study from January 2012 to December 2015 of premature newborns from 28 to 36 weeks of amenorrhea in the neonatology unit of Mali Hospital. Results: From January 2012 to December 2015, we recorded 1692 inpatient newborns, including 614 preterm newborns, a frequency of 36.29%. The sex ratio was 1.43 in favor of boys. The average age of the mothers was 23.9 years with a minimum of 15 and a maximum of 47 years. The majority were housewives (92.7%). The pregnancy was poorly monitored in 51.8% of the mothers. The average gestational age was 32.9 days with extremes of 25 and 36 days. The most frequent mode of delivery was vaginal delivery (93.2%), with late prematurity in 51.5%, moderate prematurity (24.4%), extreme prematurity (18.7%) and very premature (5.4%). The mean birth weight was 1464 g with a standard deviation of 485 g and 2751 g. Prematurity was associated with neonatal infection in 49.4% of newborns, perinatal anoxia (13.9%) and hypotrophy (2.6%). The most frequent maternal risk factors were fever (83.4%), twinship (38.9%) and high blood pressure (8.6%). The average length of hospitalization was 9.75 days with extremes of 0 and 68 days. We recorded a cure rate of 57.7%, a death rate of 35.7% and a dropout rate of 6.7%. Conclusion: Prematurity is frequent in the neonatology unit of the Mali Hospital. We observed a high frequency among women of extreme age and low socio-economic and educational level. In our study we also noted a high mortality rate proportional to gestational age.

Exhibitors to Bleeding Disorders in the Context of Pre-Eclampsia: Analytical Preliminary Study About 50 Cases at Laquintinie Hospital (Douala, Cameroon)

Introduction: Pre-eclampsia is one of the major causes of maternal and neonatal morbidity and mortality in the world. The complexity of its etiopathogenesis involves, among other things, age, primi-gravidity, obesity, lack of sensitization to the partner's sperm. Our objective was to describe the socio-clinical profile of the preeclampsia pregnant woman received in consultation in our department and to investigate its influence on certain coagulation parameters (prothrombin level, activated partial thromboplastin time). Methodology: We carried out an analytical cross-sectional study from 01st November 2018 to 31st May 2019, in the gynecology and obstetrics department of the Laquintinie Hospital in Douala. We recruited 150 pregnant women including 50 preeclampsia matched to 100 non-preeclampsia all with a gestational age greater than 20 weeks of amenorrhea. The variables of interest were age, pregnancy, parity, gestational age, marital status and body mass index, Prothrombin Level (PL), and Activated Cephalin Time (ACT). Statistical tests were considered significant for a p-value <0.05. Results: The majority age group in both groups was that of 25-30 years with a mean age of 27.80 ± 5.80 in the pregnant preeclampsia; the latter was predominantly pauci-gravid, nulliparous, and grade 1 obese with a gestational age predominantly ≥ 37 weeks of amenorrhea. In linear regression analysis and unvaried regression analysis, we did not find any socio-clinical factors exposing to coagulation disorders in preeclampsia. Conclusion: Our preliminary study reveals the non-existence of socio-clinical factors exposing to coagulation disorders in preeclampsia in our setting.