Live streaming sales by web celebrities is a hot topic that is receiving increasing attention in todays society. Some scholars believe that it is mainly developed by the combination of web celebrity economy and e-commerce live streaming. Based on the literatures search and the concepts summary, this article mainly focuses on the factors which affecting the live streaming sales by web celebrities. Nowadays, with the popularity of e-commerce live streaming, a lot of enterprises are hard to survive in the cruel market just rely on traditional sales methods, they began to explore a new way to sell goods by e-commerce live streaming. On the other side, live streaming sales with web celebrities received very significant results, as a result, nowadays more and more enterprises choose to cooperate with web celebrities. Factors affecting live streaming sales by web celebrities have multiple dimensions, such as personal qualities of web celebrities, business cooperation strategies etc. The author hope that the conclusion of this article can provide some ideas to the entrepreneurs who choose to sell goods by live streaming.