Weak Correlation Research Articles

Correlation models for next-generation amplitude and cumulative intensity measures using artificial neural networks

Various next-generation intensity measures (IMs) have emerged in recent years. For instance, filtered incremental velocity, FIV3, was shown to be efficient in predicting the collapse of structures, or average spectral acceleration, Saavg, shown to be well-correlated with a wide range of response, from initiation of structural damage yielding to structural collapse. Different ground motion models (GMMs) are available to predict the probabilistic distribution of these IMs, given a set of seismological parameters. Nonetheless, a few key correlation models are still missing in the literature, which are elemental for a more holistic approach to ground motion record selection. These models are vital when performing seismic hazard analysis and ground motion record selection using state-of-the-art approaches like the conditional spectrum or generalized conditional intensity measure (GCIM) methods. This study uses a single machine-learning-based generalized ground motion model (GGMM) to estimate all the IMs. The model is based on the Next-Generation Attenuation (NGA)-West2 database and was utilized to quantify the correlations between the residuals. Correlations were calculated for intra- and inter-event residuals, but only those for total residuals are presented here, given their utility. Since the calculation of residuals comes from the same GMM and the same database of ground motions, this produces more consistent correlation coefficients between all IMs. To facilitate the usage of these correlation coefficients, predictive models of the empirical data were developed using machine-learning-based techniques, namely artificial neural networks (ANNs). It was found that FIV3 is strongly correlated with Sa(~1 s) and itself across all periods and has a weak negative correlation with duration at short periods and near-zero correlation for longer periods. Also, a stronger negative correlation between Sa and significant duration was found, compared with other prominent existing models. Direct correlation models between Sa and Saavg are also proposed.

Assessing the readability and quality of online written information on epistaxis.

The objective of this study was to assess the readability and quality of online written information on epistaxis. The terms 'epistaxis' and 'nosebleed' were entered into Google. The first six webpages generated for each search term were screened. Readability was assessed using the Flesch-Kincaid Reading Ease Score (FRES), Flesch-Kincaid Grade Level (FKGL), Simple Measure of Gobbledygook (SMOG) Index and Gunning Fog Index (GFOG). Quality was assessed using the DISCERN instrument. Spearman's correlation between quality and readability was calculated. A total of 37 websites met the inclusion criteria. The mean and 95% confidence intervals for FRES, FKGL, SMOG and GFOG were 58.9 (55.3-62.5), 9.65 (8.74-10.6), 9.18 (8.57-9.8) and 12.5 (11.5-13.5), respectively. The DISCERN score was 34.3 (32.0-36.5). Weak negative correlation was noted between DISCERN and FRES (rs = -0.15, p = 0.36). Online information on epistaxis is generally of poor quality and low readability.

Sensory-substitution based sound perception using a spinal computer–brain interface

Sensory substitution offers a promising approach to restore lost sensory functions. Here we show that spinal cord stimulation (SCS), typically used for chronic pain management, can potentially serve as a novel auditory sensory substitution device. We recruited 13 patients undergoing SCS implantation and translated everyday sound samples into personalized SCS patterns during their trial phase. In a sound identification task—where chance-level performance was 33.3%—participants (n=8\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$n=8$$\\end{document}) achieved a mean accuracy of 72.8% using only SCS input. We observed a weak positive correlation between stimulation bitrate and identification accuracy. A follow-up discrimination task (n=5\\documentclass[12pt]{minimal} \\usepackage{amsmath} \\usepackage{wasysym} \\usepackage{amsfonts} \\usepackage{amssymb} \\usepackage{amsbsy} \\usepackage{mathrsfs} \\usepackage{upgreek} \\setlength{\\oddsidemargin}{-69pt} \\begin{document}$$n=5$$\\end{document}) confirmed that reduced bitrates significantly impaired participants’ ability to distinguish between consecutive SCS patterns, indicating effective processing of additional information at higher bitrates. These findings demonstrate the feasibility of using existing SCS technology to create a novel neural interface for a sound prosthesis. Our results pave the way for future research to enhance stimulation fidelity, assess long-term training effects, and explore integration with other auditory aids for comprehensive hearing rehabilitation.

Evaluation of retinal nerve fiber layer and choroidal structure in obese children and adolescents

Aim: Obesity-related vascular damage and endothelial dysfunction have deleterious effects on the ocular vasculature. It was aimed to examine optical coherence tomography (OCT) parameters in obese and overweight children and to define their relationship with metabolic markers in this study. Methods: The patient group consisted of 26 obese, 24 overweight patients aged between 8 and 18 years. The control group consisted of 25 healthy children with normal body mass index (BMI). This was a cross-sectional observational study. Serum glucose, lipid parameters, and homeostasis model assessment of insulin resistance (HOMA-IR) were investigated. Measurement of choroidal thickness was performed with Cirrus HD-OCT (Carl Zeiss Meditec Inc., Dublin, CA, USA). Retinal nerve fiber layer (RNFL) thickness was determined by an automatic computer algorithm without the need for user measurement. Results: There were no differences in subfoveal, nasal, temporal choroidal thickness, and RNFL between obese, overweight, and control groups (p>0.05). A positive (linear) moderate relationship was found between RNFL and the HOMA-IR of 26 patients in the obese group (r=0.389) (p=0.049). A positively weak correlation was found between height and RNFL in obese patient group (r=0.264, p=0.028). Conclusion: In the study, RNFL thickness increased as HOMA-IR level increased in obese children and adolescents. RNFL decreased as the height increased in obese children and adolescents. We believe that more comprehensive data about the effect of obesity on RNFL and choroidal thickness will be obtained with prospective studies in which the obese patient group with insulin resistance is taken separately and disease durations are defined, and long-term patient follow-up is performed.

Hydraulic traits exert greater limitations on tree-level maximum sap flux density than photosynthetic ability: Global evidence

Transpiration is a key process that couples the land-atmosphere exchange of water and carbon, and its maximum water transport ability affects plant productivity. Functional traits significantly influence the maximum transpiration rate; however, which factor plays the dominant role remains unknown. SAPFLUXNET dataset, which includes sap flux density of diverse species worldwide, provides fundamental data to test the importance of photosynthetic and hydraulic traits on maximum tree-level sap flux density (Js_max). Here, we investigated variations in Js_max of 2194 trees across 129 species using data from the SAPFLUXNET dataset, and analysed the relationship of Js_max with photosynthetic and hydraulic traits. Our results indicated that Js_max was positively correlated with photosynthetic traits at both leaf and tree level. Regarding hydraulic traits, Js_max was positively related to xylem hydraulic conductivity (Ks), leaf-specific hydraulic conductivity (Kl), xylem pressure inducing 50 % loss of hydraulic conductivity (P50), xylem vessel diameter (Vdia), and leaf-to-sapwood area ratio (AlAs). Random forest model showed that 87 % of the variability in Js_max can be explained by functional traits, and hydraulic traits (e.g., P50 and sapwood area, As) exerted larger effects on Js_max than photosynthetic traits. Moreover, trees with a lower sapwood area or depth could increase their sap flux density to compensate for the reduced whole-tree transpiration. Js_max of the angiosperms was significantly higher than that of the gymnosperms. Mean annual total precipitation (MAP) were positively related to Js_max with a weak correlation coefficient. Furthermore, Js_max showed a significant phylogenetic signal with Blomberg's K below 0.2. Overall, tree species with acquisitive resource economics or more efficient hydraulic systems show higher water transport capacity, and the efficiency of xylem hydraulic system rather than the demand for carbon uptake predominantly determines water transport capacity.

THE RELATIONSHIP OF COVID-19 FEAR WITH PREOPERATIVE ANXIETY AND POSTOPERATIVE ANALGESIC REQUIREMENT IN TOTAL HIP AND KNEE ARTHROPLASTY PATIENTS

It was conducted to determine the relationship between fear of Covid-19 and preoperative anxiety and postoperative analgesic requirement in total hip and knee arthroplasty patients. This descriptive study was conducted with 331 patients scheduled for arthroplasty who were hospitalized in the orthopedic clinic of a hospital in eastern Turkey between March 2022-2023. Fear of covid-19, state anxiety inventory, and visual analogue pain scale were used. The mean age of the patients was 61.9±14.4 years, 52.0% had undergone total knee arthroplasty, and there was no relationship between Covid-19 fear score and state anxiety score. A positive significant correlation was found between opioid requirement and Covid-19 fear score on the first and second days after surgery. A weak positive correlation was found between non-steroidal anti-inflammatory drug (NSAID) requirement and Covid-19 fear score on the zero, first and second days after surgery. A weak negative correlation was found between paracetamol use and Covid-19 fear score on the first and second days. It was determined that the Covid-19 fear experienced by the patients before surgery was not associated with preoperative anxiety and increased the use of analgesics such as NSAIDs and opioids after surgery.

Exploring the Structure-Activity Relationship of COX Inhibitors with Anticancer Effects: A Comprehensive Review.

Cancer is a multifaceted disease with high mortality rates, and current treatments face challenges such as chemoresistance and tumor adaptation. Since Virchow reported the first case of cancer-related chronic inflammation, numerous clinical and epidemiological studies have indicated that around 15-20% of malignant tumors are caused by inflammation. Cyclooxygenase-2 (COX-2), which is the key enzyme in inflammation, has been implicated in tumorigenesis through various mechanisms, including promoting angiogenesis, inhibiting apoptosis, and enhancing the invasiveness of cancer cells. Moreover, COX inhibitors have demonstrated a substantial reduction in death rates associated with esophageal and colon cancer. In this context, targeting COX-2 is an effective strategy for cancer prevention and treatment. This review focuses on the analysis of studies conducted between 2014 and 2024, which evaluate the structure-activity relationship of molecules intended to exhibit cytotoxic activity through COX inhibition. The studies followed both classical and non-classical COX-2 selective drug design strategies. While some focused on the classical approach, utilizing diaryl heterocyclic structures, others explored non-classical designs with a cyclic central scaffold and a linear core. Additionally, several manuscripts employed well-known COX inhibitors, including licofelone, indomethacin, naproxen, tolfenamate, celecoxib, flumizole, and ketoprofen, as starting points for further derivatization and optimization. Cytotoxic activity was evaluated using various cell lines, including MCF- 7, HCT-116, and A549, through assays such as MTT, CellTiter, and MTS. Additionally, studies examined the relationship between COX-2 inhibition and key cancer pathways, including apoptosis and the involvement of enzymes like HDAC, EGFR, and topoisomerase. The majority of studies reported promising cytotoxic activity in COX-2 selective inhibitors. Compounds synthesized with diphenyl heterocyclic scaffolds exhibited enhanced COX-2 selectivity and anticancer efficacy. In particular, derivatives in studies 9, 16, and 24 demonstrated significant activity comparable to standard drugs like celecoxib and doxorubicin. However, only a few studies indicated a weak correlation between COX-2 inhibition and cytotoxicity, suggesting the need for further investigation into other cancer-related mechanisms. This review highlights the potential of COX-2 selective inhibitors in anticancer drug development. The findings support the development of selective COX-2 inhibitors with diverse chemical structures as a promising strategy for cancer therapy.

Non Invasive Preimplantation Testing for Aneuploidies in Assisted Reproduction: A SWOT Analysis.

The implementation of non-invasive PGT-A offers a new strategy to genetically assess the preimplantation embryo and to enhance IVF results. The extraction of DNA from the embryo culture medium has been sufficiently demonstrated, and the ability to obtain chromosomal information as a result is particularly interesting. As morphological criteria have proven to have a weak correlation with embryo ploidy status, this technique emerges as a promising alternative for embryo selection. It also appears reasonable that avoiding biopsy may enhance further embryo development. However, there are growing concerns regarding several aspects of this technique, such as the origin of this cell free DNA, the degree of representativeness of the whole embryo, the need for extended culture or the absence of standardized protocols. Despite the published data on good prognosis couples are promising, niPGT-A is yet to be considered a substitute for trophectoderm biopsy. The current SWOT analysis aims to summarize both resolved and unresolved issues, as well as limiting aspects of niPGT-A.

Income level as a differentiating factor in assessing the impact of migration on economic growth

Aim. To study the nature of the impact of migration on economic growth depending on the level of gross domestic product (GDP) per capita and the direction of migration flows.Objectives. Study of theoretical approaches to the research of the impact of labor migration on economic growth; analysis of factors that differentiate the assessment of the impact of migration flows on economic growth indicators; collection and analysis of statistical information for the development of econometric models for assessing the impact of migration on economic growth.Methods. The authors used general scientific methods of research, such as deduction, analysis, synthesis. Statistical methods of data analysis were applied, linear regression models were built.Results. The research shows that the impact of migration on economic growth in countries with different levels of GDP per capita is due to different factors. For developed economies, the positive factors of the impact of immigration on economic growth are replenishment of scarce labor resources; improvement of labor force quality due to structural changes caused by the transition of the permanent working-age population to new professional fields. For countries with a low level of GDP per capita we can identify a number of positive factors of the impact of emigration (with a negative balance of migration growth) on economic growth. In particular, the outflow of excess labor force creates conditions for reducing unemployment; remittances of migrants support effective demand in the consumer market, contribute to the development of the banking system and investment in the country of origin; the expansion of social ties leads to the development of human capital, increasing the potential for innovation.Conclusions. The value of correlation coefficients in the constructed regression models indicates that there is a weak correlation between the variable characterizing the volume and nature of migration in the country (the ratio of migration balance to population) and the variable characterizing economic growth (GDP per capita at purchasing power parity) only for the group of high-income countries. There is little statistical dependence of these variables for other groups of countries. With regard to econometric modeling of the impact of migration on economic growth, this means that it is necessary to develop separate models for each group of countries depending on the level of GDP per capita and the direction of migration flows.

Higher protein intake may benefit in patients with prolonged mechanical ventilation.

Patients with prolonged mechanical ventilation (PMV) is usually associated with muscle wasting and diaphragm weakness, resulting in high medical costs and mortality. Adequate energy and protein intake were beneficial in sarcopenia patients. We aimed to investigate the impact of protein intake in weaning parameters in patients with PMV. We enrolled patients with PMV (mechanical ventilation ≥6 h/day for ≥21 days) from a respiratory care center (RCC) of a tertiary medical center from December 2020 to October 2022, and classified them into weaning success and weaning failure groups. The patients' characteristics, nutrition records, weaning parameters and outcomes were analyzed. A total of 289 patients were included (mean age 73.5 years). Of the 289 patients, 149 were weaned successfully and 140 were not. The average protein intake was higher in the weaning success group than in the weaning failure group (1.22 ± 0.320 versus 0.99 ± 0.332 g/kg/day, p < 0.001). No significant differences were noted in the average calorie intake and whey protein intake between the two groups. RSBI <90 breaths/min/L (OR = 2.38, p = 0.045), serum albumin at 4th week ≥3 g/dL (OR = 2.89, p = 0.027), daily protein intake ≥1.01 g/kg/day (OR = 8.10, p < 0.001), PaO2/FiO2 (PF) ratio ≥ 300 (OR = 2.56, p = 0.027) were independent predictors for weaning from ventilator. Weak positive correlations were found between average protein intake with PF ratio (r = 0.1576, p = 0.0227) and PaO2 (r = 0.13359, p = 0.0497). Daily protein intake had positively correlated with PF ratio and had independently benefit for weaning in patients with PMV.

Anatomical analysis of the abdominal aorta in a South African sample: influence of age and sex.

The anatomy of the abdominal aorta (AA) varies with age and sex; however, limited studies exist from South Africa. Given the increased incidence of endovascular treatment of the AA, reference values are relevant for interventionalists for improving the safety of endovascular procedures. Therefore, the study aimed to determine the lengths, diameters and tortuosity of the AA and their association with age and sex in a South African sample. After ethical approval, 97 computed tomography angiography (CTA) scans from an adult sample (54 male and 43 female), mean age 48.5 ± 17.2 years were analysed. The aortic length was measured from the origin of the coeliac trunk to the bifurcation point of the AA. The lumen diameters of the aorta were measured at three landmarks. Tortuosity of the AA was quantified with the tortuosity index and its prevalence was determined. The AA was longer in males and showed a significant weak positive correlation with age. The mean diameters of the AA were larger in males and had a significant strong positive correlation with age in both sexes (p < .001). There was a strong positive correlation between age and tortuosity in both sexes (p < .001). The prevalence of a tortuous c-shaped-curve phenotype was 8.2%, with a 7:1 male-to-female ratio. The dimensions and tortuosity differed between sexes and varied significantly with age. These findings may contribute towards reference values in the South African setting, inform patient selection and complement decision-making of endovascular treatment strategies.

Study on Spatiotemporal Characteristics and Influencing Factors of High-Resolution Single-Season Rice

Single-season rice describes the area under rice cultivation from May–October of the year. Many scholars have used lower-resolution data to study single-season rice in different regions, but using high-precision and high-resolution single-season rice data can reveal new phenomena. This paper uses a long-time-series, high-precision, and high-resolution single-season rice cultivation dataset to conduct an in-depth analysis of the spatial–temporal variability characteristics of single-season rice in Jiangsu Province, China, from 2017 to 2021. It explores the correlation between meteorological factors and greenhouse gasses for single-season rice. It analyzes the driving role of social factors on single-season rice. The results showed that single-season rice was mainly grown in the central and northeastern regions of the study area. The single-season rice cultivation was significantly reduced in 2020 due to the impact of COVID-19. Single-season rice strongly correlates with meteorological factors in time but shows a weak spatial correlation. This is because human factors largely dominate the area under single-season rice cultivation. Methane emissions in the study area are mainly influenced by anthropogenic activities rather than single-season rice. Social factors are essential in controlling single-season rice cultivation in the study area. This study was conducted in Jiangsu Province, China. Still, the methodology and results have important implications for agricultural production and environmental management studies in other regions, and some findings have general applicability.

Fast Color Image Encryption Algorithm Based on DNA Coding and Multi-Chaotic Systems

At present, there is a growing emphasis on safeguarding image data, yet conventional encryption methods are full of numerous limitations. In order to tackle the limitations of conventional color image encryption methodologies, such as inefficiency and insufficient security, this paper designs an expedited encryption method for color images that uses DNA coding in conjunction with multiple chaotic systems. The encryption algorithm proposed in this paper is based on three-dimensional permutation, global scrambling, one-dimensional diffusion and DNA coding. First of all, the encryption algorithm uses three-dimensional permutation algorithms to scramble the image, which disrupts the high correlation among the image pixels. Second, the RSA algorithm and the SHA-256 hashing algorithm are utilized to derive the starting value necessary for the chaotic system to produce the key. Third, the image is encrypted by using global scrambling and one-dimensional diffusion. Finally, DNA coding rules are used to perform DNA computing. The experimental results indicate that the encryption scheme exhibits a relatively weak inter-pixel correlation, uniform histogram distribution, and an information entropy value approaching eight. This shows that the proposed algorithm is able to protect the image safely and efficiently.

Influence of Chemical Weathering and Microcracks on Permeability Variations in Crystalline Rocks

Rock permeability, an important factor in subsurface fluid migration, can be influenced by microcracks and chemical weathering due to water–rock interactions. Understanding the relationship between permeability, chemical weathering, and microcracks is crucial for assessing fluid flow in rocks. This study focuses on the hydrogeological characteristics of granite and gneiss, potential host rocks for high-level radioactive waste disposal in South Korea. Samples were analyzed for permeability, porosity, P-wave velocity, and chemical weathering indices. Regression analysis revealed a weak correlation between permeability and both porosity and rock density, while an inverse correlation was observed between permeability and chemical weathering indices. Interestingly, some samples showed low permeability (10−21 to 10−22 m2) despite high weathering, while others showed high permeability (10−18 to 10−19 m2) despite low weathering. SEM-EDS analysis indicated the presence of microcracks within the rocks or the filling of these cracks with secondary minerals. The findings suggest that chemical weathering generally increases pore size and porosity, but actual permeability can vary depending on the presence and connectivity of microcracks and the extent to which they are filled with secondary minerals. Therefore, both chemical weathering and microcrack connectivity must be considered when evaluating the hydrogeological characteristics of crystalline rocks.

Long-Term Outcomes of Cataract Surgery: Analysis of Visual Acuity and Intraocular Pressure in a Tertiary Care Center

Abstract: Posterior capsule opacity (PCO) is a common complication following cataract surgery, caused by the proliferation of residual lens epithelial cells. This study aimed to evaluate the long-term effects of Nd:YAG laser capsulotomy on intraocular pressure (IOP) and visual acuity in PCO patients. This was a retrospective descriptive study. Samples were 24 patients diagnosed with PCO who underwent Nd:YAG laser capsulotomy at Prof. Dr. R. D. Kandou Hospital, Manado, from January 1, 2022, to January 1, 2024. The study recorded pre- and post-procedure IOP and best-corrected visual acuity (BCVA) data. Descriptive analysis, including paired t-tests, was used to assess changes in IOP and BCVA over an average follow-up period of 19.2 months. The results showed a statistically significant improvement in BCVA (p=0.000), with mean values improving from 0.72 to 0.27 LogMAR. A significant reduction in IOP was also observed (p=0.015), with long-term IOP remaining stable. A weak correlation was found between follow-up duration and IOP variation (p=0.02). In conclusion, Nd:YAG laser capsulotomy significantly improves visual acuity and stabilizes intraocular pressure in the long term for PCO patients, suggesting its effectiveness in managing post-cataract surgery complications. Keywords: posterior capsule opacity; Nd:YAG laser capsulotomy; intraocular pressure; visual acuity; cataract surgery Methods: A retrospective descriptive study was conducted on 24 patients diagnosed with PCO who underwent Nd capsulotomy at RSUP Prof Dr. R. D. Kandou Central Hospital, Manado, from January 1, 2022, to January 1, 2024. The study recorded pre- and post-procedure IOP and Best-Corrected Visual Acuity (BCVA) data. Descriptive analysis, including paired t-tests, was used to assess changes in IOP and BCVA over an average follow-up period of 19.2 months. Results: The study revealed a statistically significant improvement in BCVA (p = 0.000), with mean values improving from 0.72 to 0.27 LogMAR. A significant reduction in IOP was also observed (p = 0.015), with long-term IOP remaining stable. A weak correlation was found between follow-up duration and IOP variation (p = 0.02). Conclusion: Nd capsulotomy significantly improves visual acuity and stabilizes IOP in the long term for PCO patients, suggesting its effectiveness in managing post-cataract surgery complications.

Progression-free survival versus post-progression survival and overall survival in WHO grade 2 gliomas.

Progression-free survival (PFS) remains to be validated as an outcome measure for diffuse WHO grade 2 gliomas, and knowledge about the relationships between PFS, post-progression survival (PPS), and overall survival (OS) in this subset of tumors is limited. We sought to assess correlations between PFS and OS, and identify factors associated with PFS, PPS, and OS in patients treated for diffuse supratentorial WHO grade 2 gliomas. We included 319 patients from three independent observational cohorts. The correlation between PFS and OS was analyzed using independent exponential distributions for PFS and time from progression to death. Cox proportional hazards models were used to determine the effects of covariates on PFS, PPS, and OS. The overall correlation between PFS and OS was rs0.31. The correlation was rs 0.37 for astrocytomas and rs 0.19 for oligodendrogliomas. Longer PFS did not predict longer PPS. Patients with astrocytomas had shorter PFS, PPS, and OS. Larger preoperative tumor volume was a risk factor for shorter PFS, while older age was a risk factor for shorter PPS and OS. Patients who received early radio- and chemotherapy had longer PFS, but shorter PPS and OS. We found a weak correlation between PFS and OS in WHO grade 2 gliomas, with the weakest correlation observed in oligodendrogliomas. Our analyses did not demonstrate any association between PFS and PPS. Critically, predictors of PFS are not necessarily predictors of OS. There is a need for validation of PFS as an endpoint in diffuse WHO grade 2 gliomas.

Can indoor plants reduce formaldehyde levels in the anatomy dissection hall? A study to evaluate the practicality of using plants in reducing formaldehyde levels

Background Formaldehyde a commonly used embalming fluid for the preservation of cadavers, produces numerous short and long-term side effects on the students and staff working with it. Indoor plants have been shown to reduce atmospheric formaldehyde levels. The purpose of the study was to compare the efficacy of indoor plants in reducing formaldehyde levels in ambient air to levels deemed safe by WHO standards Methods The study was conducted in the storage room of the Anatomical dissection hall. 7 potted plants of one variety were kept in the storage room for 14 days and the Formaldehyde reading was measured using a VOC (Volatile Organic Compound) monitor. Then the same was done with no plant. This cycle was repeated 2 more times, with two different plant species. The three spieces of plants used for this study were as follows: Dracaena trifasciata, Epipremnum aureum, Spathiphyllum. Results The results were analysed and compared and it was determined that the effect of having a plant present versus having no plant present on the Formaldehyde concentration in the air was inconclusive as Dracaena trifasciata failed to reject the null hypothesis altogether (p-value&gt;0.05), while Epipremnum aureum and Spathiphyllum rejected the null hypothesis (p-value&lt;0.05), however they both had a weak positive correlation with formaldehyde concentration. Conclusion The efficacy of indoor plants in reducing formaldehyde levels in ambient air needs to be further explored and validated since all the prior studies conducted were in controlled environment and should be done in a real time scenario for its practical and beneficial uses.

Differences in eating behaviours and mothers attitudes between baby-led weaning vs. traditional spoon-feeding approaches in Turkiye

This study was aimed to examine the differences in eating behaviours and mothers attitudes between baby-led vs. traditional spoon-feeding approaches and its effect on eating behaviours in preschool children. The study was conducted with 150 mothers of children aged 2–6, who applied to the Pediatrics Polyclinic of Başkent University Ankara Hospital, between December 2022 and February 2023. Sociodemographics, biochemical parameters were recorded to form. Maternal attitudes and eating behaviours of children were evaluated with Mother's Attitudes Towards the Feeding Process Scale (MATFP) and Early Childhood Adaptive Eating Behaviour Scale (ECAEB), respectively. The mean age of the children was 43.80 ± 11.04 months and 51.3% of them were girls. A weak negative correlation was found between the ECAEB total scores and the child age (r = −0.196, p < 0.05). A moderate positive correlation was found between the total scores of the MATFP and ECAEB (r = 0.699, p < 0.001). There wasn't significant difference between the MATFP total scores who chose baby-led weaning or traditional feeding (p > 0.05). According to the ECAEB; aggression and reaction to main meal order subgroup scores of children who consumed pureed vegetables until the ninth month were higher than those who didn't consume them (p < 0.05). Mothers who prefer the TSF offer their babies more blenderized and pureed foods, while those who prefer the BLW serve fork-mashed, steamed and sliced foods (p < 0,05). As the mothers‘ subscale scores for negative affect during meals, attitudes about insufficient/unbalanced feeding, negative feeding strategies, forced feeding, reaction to viewpoint of others increase, so did their subscale scores for child reluctance, eating refusal associated with sensory causes, aggression, reaction to main meal order increase. Consequently, it's believed that maternal attitudes and actions should be taken into account while evaluating the eating habits of toddlers.

Acute Quetiapine Intoxication: Relationship Between Ingested Dose, Serum Concentration and Clinical Presentation-Structured Literature Review and Analysis.

Over the past decade, quetiapine has become one of the most commonly used psychotropic drugs in acute intoxication events worldwide. A structured literature review and analysis were conducted to assess the relationship between the kinetic and dynamic profiles in acute quetiapine intoxication. The correlation between dose and peak serum concentration (cmax) was determined using Pearson's correlation coefficient. Binary logistic regression was used to evaluate dose and cmax as predictors of the most common clinical events, signs and symptoms. One hundred and thirty-four cases of acute quetiapine ingestion were included in the analysis, with a median ingested dose of 10 g and a median cmax of 4 mg/L. The typical half-life was estimated to be 16.5 h, significantly longer than at therapeutic doses. For the immediate-release formulation, a biphasic disposition could not be excluded. Dose and cmax demonstrated a weak but significant correlation (r = 0.256; N = 63; p = 0.043). Central nervous system depression and tachycardia were the most common clinical signs. Higher doses and concentrations increased the risk of severe intoxication and were good predictors of intubation, tachycardia, hypotension, QTc prolongation and seizures, but not QRS prolongation, arrhythmia, heart block, hypokalaemia or acidosis. The thresholds for dose and cmax that increased the risk for individual signs and symptoms varied widely. However, doses > 3 g or cmax > 2 mg/L can be considered as alert levels that represent a high risk for severe clinical course of acute quetiapine intoxication.

Impact of anterior cruciate ligament injury on functional capacity and pain: an analysis differentiated by age and gender

Anterior cruciate ligament (ACL) injuries significantly impact knee function, particularly in active populations. This study explores functional capacity and pain post-ACL reconstruction in relation to age, gender, and physical activity. A total of 41 participants who underwent ACL reconstruction were analyzed. Data were collected on age, sex, physical activity level, and pain frequency/intensity. The sample included 56.10% women (n=23) with an average age of 30.27 ± 10.18 years. Among the participants, 19.51% engaged in light activity, 26.83% in moderate, 7.32% in vigorous, 24.39% in very vigorous, and 21.95% were unable to perform any activity. Significant age differences were observed in moderate activity (p = 0.017), with older women more likely to engage in moderate activity. Logistic regression revealed age as a key factor affecting activity level (p &lt; 0.05), and sex had marginal significance (p ≈ 0.054), suggesting men may perform more intense activities. Pain frequency and intensity showed weak correlations with age (p &gt; 0.05), but women reported higher pain levels than men. The average functional ability dropped from 8.73 before the injury to 5.80 post-surgery. Men reported more pain than women, although t-tests showed no statistically significant differences between genders in functional capacity before or after surgery. ACL reconstruction reduces knee function across genders, with men reporting higher pain intensity. Age significantly impacts activity level, emphasizing the need for targeted rehabilitation strategies. Post-surgical recovery programs should consider individual differences in age and sex to optimize outcomes and enhance recovery.