Light-front Fock state wavefunctions encode the bound state properties of hadrons in terms of their quark and gluon degrees of freedom at the amplitude level. The freedom to choose the light-like quantization four-vector provides an explicitly covariant formulation of light-front quantization and can be used to determine the analytic structure of light-front wave functions. The AdS/CFT correspondence of large N_C supergravity theory in higher-dimensional anti-de Sitter space with supersymmetric QCD in 4-dimensional space-time has interesting implications for hadron phenomenology in the conformal limit, including an all-orders demonstration of counting rules for exclusive processes. String/gauge duality also predicts the QCD power-law behavior of light-front Fock-state hadronic wavefunctions with arbitrary orbital angular momentum at high momentum transfer. The form of these near-conformal wavefunctions can be used as an initial ansatz for a variational treatment of the light-front QCD Hamiltonian. I also briefly review recent work which shows that some leading-twist phenomena such as the diffractive component of deep inelastic scattering, single spin asymmetries, nuclear shadowing and antishadowing cannot be computed from the LFWFs of hadrons in isolation.
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