Vegetation restoration and farmland irrigation are important environmental factors affecting the water cycle process in basins. Analyzing the impact of vegetation restoration and farmland irrigation on runoff is an international frontier and hot topic in current research, which is crucial for the management and protection of water resources, especially for the ecological protection and high-quality development of basins. Based on the normalized difference vegetation index (NDVI), effective irrigated area (EIA), and meteorology and hydrology data for Wujiang River (WJR), this research aims to quantitatively calculate the influence degree of vegetation recovery, agricultural irrigation, and climatic variability on discharge alteration in WJR. First, Mann–Kendall and Pettitt approaches were used for recognizing the mutation year of streamflow data at Wulong station from 1982 to 2015. Then, a corrective Budyko model was built by constructing multiple linear regression equations for the NDVI, climate factors, EIA, and Budyko parameters. Finally, the corrective Budyko model was adopted to reveal how vegetation restoration, agri-cultural irrigation, and climate variation influence discharge alteration in WJR. The results showed the following: (1) Both runoff depth (R) and rainfall (Pr) exhibited a non-significant de-clining tendency, while potential evapotranspiration (ET0) demonstrated a non-significant in-creasing tendency. The NDVI and EIA both demonstrated a notable upward tendency (p<0.01). (2) The mutation year of discharge in WJR was 2004. (3) The underlying surface parameters ω have a strong correlation with vegetation, agricultural irrigation, and climate factors. (4) The contribution of rainfall (Pr), potential evapotranspiration (ET0), NDVI, EIA, and human activities to runoff depth in WJR were 57.34%, 24.67%, -11.75%, 11.71%, and 18.02%, respectively. This re-search is helpful for elucidating the effects of ecological construction measures and agricultural irrigation on streamflow in WJR, and offers great scientific significance and practical value for understanding the evolution mechanism of water circulation and for managing regional water resources.