The study conducted in two regions of Guinea Bissau, Oio and Cacheu, focusing on the characterization of the groundwater supplies sampled during the dry season and their associated risks for human health. Twenty samples were collected in wells located nearby pit latrines. In situ analyses were conducted with Semi-quantitative test strips for the determination of turbidity, pH, chloride, carbonate, sulfites, ammonium, nitrite and nitrate. The analysis of metals was performed by an ICP-MS Elan DRC-e and an ICP-OES Optima 8000. The Target Hazard Quotient (THQ) was applied to evaluate the risk of developing chronic systemic effects derived from exposure to metals. Values of concern of turbidity ammonium, and pH values were lower than the normal range for drinking water in most samples. From both regions, Fe and Al were occasionally found with values higher than the international thresholds fixed by the World Health Organization and by the European Commission for drinking water, while, only in one sample from Cacheu region Pb was found significantly above these limits. THQs resulted next to the level of risk (1) for the highest values found of Al, As, Fe and Mn. Of great concern is the resident risk obtained from a well water of Cacheu for the highest value of Pb (96.8μg/L), because the values of the resident risk found of 1 and 0.7 for child and adults respectively. The results obtained highlighted a close correlation between the chemistry of water and sediment and a correlation with the proximity of the water supplies with the latrines. This study evidenced the potential toxicity of the water supplies for the local populations and the risk of developing chronic systemic effects due to some physico-chemical parameters, the importance of functioning water pipeline system, the importance of maintaining adequate distance between latrines and drinking water access.
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