The present study reports on the quantification of the economic feasibility and environmental sustainability potential of a biogas-based pressurized grid on a rural livestock farm in Cuba. Three different grids (Grid 1: Niña Bonita, Grid 2: Sabanilla, and Grid 3: Dos Ríos) were evaluated, with the main differences between them being the number of anaerobic digesters and the substrates to be managed. For this purpose, the economic evaluation was carried out based on the cost of the equipment. In addition, the Life Cycle Assessment (LCA) method was used to obtain the environmental profile of the whole system and each grid. The cost analysis included the monetization of cost savings derived from the monetization of fertilizer and energy sources. The selected functional unit was the 10 kg chemical oxygen demand (COD) in livestock manure and slaughterhouse wastewater. The results show the need for grid interconnection to balance biogas production and consumption. The proposed model demonstrates the economic feasibility of the biogas-based pressurized grid, with a payback period, internal rate of return (IRR), and net present value (NPV) of 4.6 years, 38%, and $2 188 993.08, respectively. Studies confirm that the price of digestate is critical to the economics of the process, with a high sensitivity to project profitability. From an environmental point of view, Grid 2 performed the worst, mainly due to CO2 and N2O emissions (mainly in the lagooning process). However, the current grid supports the diversion of lagooning effluent for the irrigation of nearby fodder crops. In addition, the sensitivity analysis showed that the increase in the number of cattle (doubling) is crucial for the improvement of the environmental profile. Its variation proved that the substitution of fossil-based electricity can be considered a solution to reduce the environmental burden with bioenergy.