The fire behavior of external wall insulation system on facades is assessed during LEPIR II testing. This facility involves a 600 kg wood crib fire in a 30 m3 lower compartment of a two levels high concrete structure. External flames develop in front of the facade from the fire compartment through windows with dimensions 1 × 1.5 m (W × H). In order to predict the fire exposure of a facade during the test, CFD simulations were carried out with the computational fluid dynamics code Fire Dynamics Simulator (FDS) for two full-scale experiments. The main objective of this study was to evaluate the ability of FDS to reproduce quantitative results in terms of gas temperatures and heat fluxes close to the tested facade. This is an important step before the fire performances of any insulation system can be predicted by numerical tools. A good repeatability was observed in terms of measured gas temperatures for experiments. Maximum heat release rate of the fire, close to 5 MW, was achieved after 5 min of test. When experimental results were compared with numerical calculations, good agreement was found for every quantity. The most critical zone on the facade is located above the fire room and is directly impacted by external flame outgoing from the fire compartment. Temperatures up to 500°C were observed in this zone. For the thermocouples located up to the second level opening, these probes were not located directly in the flames, but rather in the hot gases above the fire plume. The maximum temperature achieved was thus close to 400°C. The proposed model gives correct thermal loads and flames shape near the facade during calibration tests and can be used for further evaluation of combustible material on facade.