Walk Test In People Research Articles

Heart rate recovery after the 6-min walk test in people with bronchiectasis

BackgroundThe cardiac autonomic response to exercise and during recovery has been poorly explored in bronchiectasis.MethodsA longitudinal study was conducted in adults with bronchiectasis. Sociodemograhic and clinical data were collected at baseline and after 12 months of follow-up. The heart rate recovery after the first (HRR1) and second minute (HRR2) of recovery in the six-minute walk test (6MWT) was estimated in both assessments. Adjusted regression models were used to identify predictors of a delayed HRR1(HRR1≤ 14).Results104 participants with a mean (sd) age of 64 (13) years and mostly woman (67%) were included. A delayed HRR1after the baseline 6MWT was identified in 36% of participants. These participants presented a higher proportion of males, increased body mass index, higher disease severity, more likely to required hospitalisation, more impact on quality of life, lower exercise capacity, lower HR at the end of the 6MWT and lower HRR2. Disease severity (ß, 95%CI) (moderate and severeversusmild, −0.47 (−0.94 to −0.01)) and distance walked (0.34 (0.11 to 0.56)) were the independent variables associated with HRR1. Of the 45 participants who completed the entire follow-up period, 24% exhibited delayed HRR1. The presence of at least two exacerbations during the follow-up period (OR, 95%CI) (16.89 (1.44 to 197.48)) was the only predictor of a delayed HRR1in the assessment completed at the end of the study.ConclusionHRR1is related to disease severity and mainly affected by having severe exacerbations in people with bronchiectasis.

Comparing treadmill and overground versions of the two-minute walk test in people with low back pain

Purpose Individuals with Low Back Pain (LBP) often face significant disabilities, including walking limitations. We use the Two-Minute Walk Test (2MWT) to assess walking performance, comparing overground and treadmill versions for correlation and interchangeability. Material and methods A randomised cross-over study of 40 participants with LBP randomly completed the 2MWT in a hallway and on a treadmill. The correlation was analysed by the Spearman Rho correlation coefficient (r), the agreement by the Bland-Altman method, differences between the testing orders by a paired sample t-test, and the association by a univariate regression. Results A high correlation was found between the methods (r = 0.76, p < 0.01). The difference between the methods was 45.4 metres (95% CI 33.4: 57.4, p < 0.01) or 29%, with an insignificant 6.8 metres (95% CI −17.4: 31.0, p = 0.57) between the testing orders. Notably, the distance walked in the hallway served as a strong predictor, explaining a substantial portion of the variation observed in the distance covered on the treadmill (R2 = 0.61, p < 0.01). Conclusion Performance of the 2MWT overground and on a treadmill correlate highly in people with LBP. However, because participants walked 29% further in the hallway, treadmill walking is likely not an interchangeable alternative to testing when the aim is to evaluate performance.

Ventilation dynamics using a portable device coupled to the six-minute walk test in people with long-COVID syndrome: a preliminary study

ObjectiveTo investigated the dynamic ventilatory responses and their influence on functional exercise capacity in patients with long-COVID-19 syndrome (LCS).ResultsSixteen LCS patients were subjected to resting lung function (spirometry and respiratory oscillometry-RO) and cardiopulmonary performance to exercise (Spiropalm®-equipped six-minute walk test-6MWT and cardiopulmonary exercise test-CPX). At rest, spirometry showed a normal, restrictive and obstructive pattern in 87.5%, 6.25% and 6.25% of participants, respectively. At rest, RO showed increased resonance frequency, increased integrated low-frequency reactance and increased difference between resistance at 4–20 Hz (R4-R20) in 43.7%, 50%, and 31.2% of participants, respectively. The median of six-minute walking distance (DTC6) was 434 (386–478) m, which corresponds to a value of 83% (78–97%) of predicted. Dynamic hyperinflation (DH) and reduced breathing reserve (BR) were detected in 62.5% and 12.5% of participants, respectively. At CPX, the median peak oxygen uptake (VO2peak) was 19 (14–37) ml/kg/min. There was a significant correlation of 6MWD with both R4-R20 (rs=-0.499, P = 0.039) and VO2peak (rs=0.628, P = 0.009). Our results indicate that DH and low BR are contributors to poor exercise performance, which is associated with peripheral airway disease. These are promising results considering that they were achieved with simple, portable ventilatory and metabolic systems.

The reliability and validity of the 3-m backward walk test in people with Parkinson's disease.

People with Parkinson's disease (PwPD) lose the ability in backward walking which is an important part of mobility in daily life. The 3-m backward walk test (3MBWT) evaluates backward walking; however, its reliability and validity have not been examined in PwPD yet. To examine (1) the test-retest reliability of the 3MBWT in PwPD; (2) the minimum detectable change in the 3MBWT times; (3) the concurrent and known-groups validity of the 3MBWT; and (4) the optimum cutoff time which best discriminates fallers from non-fallers with Parkinson's disease (PD). This cross-sectional study included 36 PwPD and 33 healthy people. The 3MBWT was conducted with the 10-m walk test, timed up and go test, Berg Balance Scale, four square step test, activity-specific balance confidence scale, Movement Disorders Society Sponsored Unified Parkinson's Disease Rating Scale, and Hoehn and Yahr Scale. The 3MBWT demonstrated excellent test-retest reliability (ICC = 0.965). The MDC of 2.13s was determined. The 3MBWT had moderate to high correlations with the other outcome measures (correlation coefficient ranged from -0.592 to 0.858). On the 3MBWT times, there were significant differences between PwPD and healthy people, and between fallers and non-fallers with PD (p < 0.001 and p < 0.001, respectively). A 3MBWT time of 10.31s was found to best discriminate fallers from non-fallers with PD. The 3MBWT is a reliable, valid, and easy to administer outcome measure to assess backward walking performance in PwPD, indicating it to be used in practice and research.

Retention of kinematic patterns during a 6-minute walk test in people with knee osteoarthritis

BackgroundKnee osteoarthritis (OA) is a chronic condition affecting the entire joint and surrounding tissue, resulting in pain, stiffness and impaired movement. Recent studies have suggested the use of physical performance tests, such as the six-minute walk test (6MWT) to assess joint function for those with knee OA. This study assessed lower limb sagittal plane joint angles during a 6MWT for people with mild-moderate knee OA. MethodsThirty-one participants (18 male, 13 female; 62.9 ± 8.4 years) with knee OA were recruited. Gait data were collected in a single session during which participants completed a 6MWT around a 20 m course. Sagittal plane joint angles for the hip, knee and ankle were calculated during the first and last minute of the 6MWT. Statistical parametric mapping (SPM) was used to investigate changes in kinematic traces over the gait cycle. ResultsMean joint angles for the hip and knee showed no significant differences between the first and last minute of the 6MWT. Ankle joint kinematic traces indicated there to be a decrease in plantarflexion approaching toe-off in the last minute of the test – a 1.5° reduction from the first minute. No significant differences were calculated for walking speed or joint range of motion. DiscussionThe lack of significant change in joint kinematic parameters and walking speed suggests the relative fatigue and pain burden to the participant over the duration of the 6-minute period is insufficient to elicit any mechanical changes to walking gait.

Six Minute Walk Test in People with Tuberculosis Sequelae

Background: Tuberculosis often brings about diffuse fibrotic and other changes to lung tissue also consolidation of lung tissue prompting a decrease in generally lung tissue compliance. Following tuberculosis, the functional status of people is reduced e.g., impaired ventilation and gas exchanges leading to shortness of breath, muscular deconditioning, and a functional status decline is seen Objective: The purpose of this study was to evaluate and compare the six-meter walk distance and physical functional capacity (VO2 max) in 40 – 65 years people with pulmonary tuberculosis and healthy subjects. Methods: Forty healthy subjects (20 males and 20 females) and forty subjects with pulmonary tuberculosis (30 males and 10 females) took part in this study. All the subjects underwent a six min walk test. Walk-work was calculated and used for evaluating functional capacity. To examine for significant relationships Pearson product correlation was used Results: A significant difference was found between the groups in regards to 6MWT distance (p &lt; 0.05). For height and body mass index (BMI) Pearson product correlations with 6MWD were significant in normal individual and for the weight and BMI it was significant in the TB sequelae group. Conclusion: A significant difference was found in functional capacity in terms of VO2max between healthy and patients with TB was found. TB sequelae individuals’ group, 52.6% patients had a VO2 max under 21 milliliter per kilogram per minute that brought about an impressive effect of TB sequelae on endurance in regards to cardiorespiratory system. Keywords: functional capacity, hospital, six-minute walk test, tuberculosis

Determinants of 6-minute walk test in people with Parkinson's disease.

Most of the previous studies, investigating determinants of 6-minute walk test (6MWT), were conducted on small sample sizes and/or have not explored different aspects such as freezing of gait, physical activity, gender, dual-task cost, and/or have not been able to explain large portion of variation in 6MWTin people withParkinson's disease. This study aimed to investigate the determinants of 6MWT, including aspects that previous studies have not explored. In this descriptive cross-sectional study, 6MWT determinants were investigated upon 42 people with Parkinson's disease. After recording participants' demographic data, walking capacity, disease stage, severity of motor symptoms, freezing of gait, balance, physical activity, fear of falling, functional balance, and dual-task cost values were evaluated and grouped into modifiable and unmodifiable variables to investigate possible therapeutic benefits aiming improvement in walking capacity. The mean distance for 6MWT was 401.7 ± 92.7m. Significant differences between women and men were found for height, walking capacityand speed, fear of falling, andfunctional balance(p<0.05). Hierarchical regression analysis showed that gender, age, and time since diagnosis significantly explained 52.4% of the variance in 6MWT and disease stage, freezing of gait, dual-task cost, and functional balance added an extra 35.6% to the explained variance. These results showed that gender, age, disease stage, freezing of gait, dual-task cost, and functional balance values are significant contributors to the variance in 6MWT. Therefore, while planning rehabilitation strategies to improve walking capacity, one should focus on these aspects in people with Parkinson's disease.

The psychometric properties of the figure-of-eight walk test in people with Parkinson's disease

Purpose To investigate: (1) the interrater, and test–retest reliability of the figure-of-eight walk test (F8WT) in people with Parkinson's disease (PwPD); (2) the minimum detectable change in the F8WT times; (3) the concurrent and known-groups validity of the F8WT times; and (4) the cut-off times that best discriminate PwPD from healthy people and fallers from non-fallers with PD. Methods This was a cross-sectional study. Forty-three PwPD and 34 healthy people were recruited. The F8WT was performed along with the timed up and go test, 10 m walk test, Berg Balance Scale, Activities-Specific Balance Confidence Scale, Unified Parkinson's disease Rating Scale, and Hoehn and Yahr Scale. Results The F8WT showed good interrater and test–retest reliability (ICC = 0.964–0.978 and ICC = 0.905–0.920, respectively). The MDC was 2.77 s. The F8WT was correlated with other outcome measures. Significant differences in the F8WT times were found between PwPD and healthy people and between fallers and non-fallers with PD (p < 0.001 and p < 0.001, respectively). The cut-off times of 8.43 s best discriminated PwPD from healthy people, while 11.19 s best discriminated fallers from non-fallers with PD. Conclusions The F8WT is a reliable, valid, and easy-to-administer tool in assessing the walking skill of PwPD. Implications for rehabilitation The figure-of-eight walk test (F8WT) is a reliable, valid, and clinically available tool for assessing walking skill in Parkinson's disease (PD). The minimal detectable change of the F8WT is 2.77 s, which may help to determine any real change in walking skill after any intervention. The F8WT correlated with functional mobility, gait speed, balance, balance confidence, and severity and stage of PD. The F8WT times may detect impaired walking skill between people with PD and healthy people, and between fallers and non-fallers with PD.

Gait parameters assessed with inertial measurement unit during 6-minute walk test in people after stroke.

Gait impairments are among the main issues for stroke survivors as they are often linked with a lack of endurance capacity, balance impairments and functional limitations. These conditions can be carefully assessed by combining an endurance capacity test, the 6-minute walk test (6MWT), with the analysis of gait performed by an inertial measurement unit (IMU). We investigated the evolution of gait spatiotemporal and kinematic parameters during the 6MWT and compared it with age-matched healthy subjects. Moreover, gait parameters and 6MWT distance were associated with clinical outcome scales. In a postacute rehabilitation general hospital, we performed an observational study. Subjects with a single cortical stroke were recruited into the stroke group (SG). An age-matched healthy group (HG) was also recruited. All participants performed a 6MWT while wearing an IMU. The outcomes considered were 6MWT distance, gait spatiotemporal and kinematic parameters, and symmetry. Before the test at each subject, in the SG was administered Berg balance scale, Canadian neurological stroke scale and motricity index. 32 subjects were recruited into the SG, and 12 into the HG. Between the paretic and nonparetic limbs of the SG, there were differences in the stance phase and single support phase (P < 0.05). SG gait speed and stride length strongly correlated with balance, strength and disability scales. The SG walked fewer meters than the HG (Δ = -260.90 m; P < 0.001). Adopting an IMU during a 6mwt resulted valuable and effective in providing meaningful information regarding both the disability and functional capabilities of SG subjects.

Quantifying Step Count and Oxygen Consumption with Portable Technology during the 2-Min Walk Test in People with Lower Limb Amputation.

Step counts and oxygen consumption have yet to be reported during the 2-min walk test (2MWT) test in persons with lower-limb amputations (LLA). The purpose of this study was to determine step counts and oxygen consumption during the 2MWT in LLA. Thirty-five men and women walked for two minutes as quickly as possible while wearing activity monitors (ActiGraph Link on the wrist (LW) and ankle (LA), Garmin vivofit®3 on the wrist (VW) and ankle (VA), and a modus StepWatch on the ankle (SA), and a portable oxygen analyzer. The StepWatch on the ankle (SA) and the vivofit3 on the wrist (VW) had the least error and best accuracy of the activity monitors studied. While there were no significant differences in distance walked, oxygen consumption (VO2) or heart rate (HR) between sexes or level of amputation (p > 0.05), females took significantly more steps than males (p = 0.034), and those with unilateral transfemoral amputations took significantly fewer steps than those with unilateral transtibial amputations (p = 0.023). The VW and SA provided the most accurate step counts among the activity monitors and were not significantly different than hand counts. Oxygen consumption for all participants during the 2MWT was 8.9 ± 2.9 mL/kg/min, which is lower than moderate-intensity activity. While some may argue that steady-state activity has not yet been reached in the 2MWT, it may also be possible participants are not walking as fast as they can, thereby misclassifying their performance to a lower standard.

Test-retest reliability and correlates of the 6-min walk test in people with alcohol use disorders.

People with alcohol use disorders (AUD) are at a higher risk for physical co-morbidities. Consequently, their daily life functioning needs to be reliably assessed and followed-up. We examined the reliability of the 6-min walk test (6MWT) in a cohort of inpatients with AUD. Secondary aims were to assess minimal detectable changes (MDC95 ), practice effects and associations of the 6MWT with demographical and clinical variables. Two 6MWTs were administered within 3 days to 45 (32♂) inpatients with a DSM-5 diagnosis of AUD. Physical complaints before and after the 6MWT were recorded. Patients performed a standing broad jump to assess muscle strength and completed the International Physical Activity Questionnaire, the Positive Affect and Negative Affect Schedule (PANAS) and Alcohol Use Disorders Identification Test. Patients walked 636.3±82.3 meters and 638.1±77.6 meters at the first and second test. The intraclass correlation coefficient was 0.94 (95% confidence interval 0.90-0.97). The MDC95 was 15 meters for men and 9 meters for women. No practice effect was detected. The presence of feet or ankle problems or pain before the test, dyspnea after the test, impaired muscle strength and lower PANAS positive affect scores were independently related to shorter 6MWT distance accounting for 67.3% of the variance. The 6MWT is a reliable tool for evaluating the functional exercise capacity in inpatients with AUD. Health care professionals should consider musculoskeletal and respiratory symptoms when interpreting fitness test outcomes in this vulnerable population.

Gait Characteristics Harvested During a Smartphone-Based Self-Administered 2-Minute Walk Test in People with Multiple Sclerosis: Test-Retest Reliability and Minimum Detectable Change.

The measurement of gait characteristics during a self-administered 2-minute walk test (2MWT), in persons with multiple sclerosis (PwMS), using a single body-worn device, has the potential to provide high-density longitudinal information on disease progression, beyond what is currently measured in the clinician-administered 2MWT. The purpose of this study is to determine the test-retest reliability, standard error of measurement (SEM) and minimum detectable change (MDC) of features calculated on gait characteristics, harvested during a self-administered 2MWT in a home environment, in 51 PwMS and 11 healthy control (HC) subjects over 24 weeks, using a single waist-worn inertial sensor-based smartphone. Excellent, or good to excellent test-retest reliability were observed in 58 of the 92 temporal, spatial and spatiotemporal gait features in PwMS. However, these were less reliable for HCs. Low SEM% and MDC% values were observed for most of the distribution measures for all gait characteristics for PwMS and HCs. This study demonstrates the inter-session test-retest reliability and provides an indication of clinically important change estimates, for interpreting the outcomes of gait characteristics measured using a body-worn smartphone, during a self-administered 2MWT. This system thus provides a reliable measure of gait characteristics in PwMS, supporting its application for the longitudinal assessment of gait deficits in this population.

Increased Cardiovascular Response to a 6-Minute Walk Test in People With Type 2 Diabetes.

Exercise is a cornerstone of management for type 2 diabetes; however, little is known about the cardiovascular (CV) response to submaximal functional exercise in people with type 2 diabetes. The aim of this study was to compare performance and CV response during a 6-minute walk test (6MWT) between people with type 2 diabetes and matched control subjects. CV response and distance walked during the 6MWT were assessed in 30 people with type 2 diabetes, matched for age, body composition, physical activity, and estimated aerobic capacity with 34 control subjects (type 2 diabetes group: 16 men, 59.8 ± 8.8 years of age, 33.3 ± 10.9% body fat, physical activity of 7,968 ± 3,236 steps·day-1, estimated aerobic capacity 31.9 ± 11.1 mLO2·kg-1·min-1; control group: 19 men, 59.3 ± 8.8 years of age, 32.7 ± 8.5% body fat, physical activity 8,228 ± 2,941 steps·day-1, estimated aerobic capacity 34.9 ± 15.4 mLO2·kg-1·min-1). People with type 2 diabetes walked a similar distance (590 ± 75 vs. 605 ± 69 m; P = 0.458) compared with control subjects during the 6MWT and had similar ratings of perceived exertion (RPE) after the 6MWT (4.19 ± 1.56 vs. 3.65 ± 1.54, P = 0.147). However, at the end of the 6MWT, people with type 2 diabetes had a higher heart rate (108 ± 23 vs. 95 ± 18 beats·min-1; P = 0.048), systolic blood pressure (169 ± 26 vs. 147 ± 22 mmHg, P = 0.003), and rate-pressure product (18,762 ± 5,936 vs. 14,252 ± 4,330, P = 0.009) than control subjects. Although people with type 2 diabetes had similar performance and RPE during the 6MWT compared with control subjects, the CV response was greater for people with type 2 diabetes, indicating greater cardiac effort for similar perceived effort and performance of 6MWT. These data suggest that observation and prescription of exercise intensity should include both perceived effort and CV response.

Minimal Clinically Important Difference of the 6-Minute Walk Test in People With Stroke.

The 6-minute walk test (6MWT) is commonly used in people with stroke. The purpose of this study was to estimate the minimal clinically important difference (MCID) of the 6MWT 2 months poststroke. We performed a secondary analysis of data from a rehabilitation trial. Participants underwent physical therapy between 2 and 6 months poststroke and the 6MWT was measured before and after. Two anchors of important change were used: the modified Rankin Scale (mRS) and the Stroke Impact Scale (SIS). The MCID for the 6MWT was estimated using receiver operating characteristic curves for the entire sample and for 2 subgroups: initial gait speed (IGS) <0.40 m/s and ≥0.40 m/s. For the entire sample, the estimated MCID of the 6MWT was 71 m with the mRS as the anchor (area under the curve [AUC] = 0.66) and 65 m with the SIS as the anchor (AUC = 0.59). For participants with IGS <0.40 m/s, the estimated MCID was 44 m with the mRS as the anchor (AUC = 0.72) and 34 m with the SIS as the anchor (AUC = 0.62). For participants with IGS ≥0.40 m/s, the estimated MCID was 71 m with the mRS as the anchor (AUC = 0.59) and 130 m with the SIS as the anchor (AUC = 0.56). Between 2 and 6 months poststroke, people whose IGS is <0.40 m/s and experience a 44-m improvement in the 6MWT may exhibit meaningful improvement in disability. However, we were not able to estimate an accurate MCID for the 6MWT in people whose IGS was ≥0.40 m/s. MCID values should be estimated across different levels of function and anchors of importance.Video Abstract available for more insights from the authors (see Video, Supplemental Digital Content 1, available at: http://links.lww.com/JNPT/A232).

Ankle Kinematics and Temporal Gait Characteristics over the Duration of a 6-Minute Walk Test in People with Multiple Sclerosis Who Experience Foot Drop.

Foot drop is a common gait impairment in people with MS (pwMS) but in some foot drop may only occur after a period of prolonged walking and may be a sign of motor fatigability. The purpose of the study was to explore whether, for pwMS, an adapted six-minute walk test (6minWT) would result in an increase in foot drop as measured using electrogoniometry. Sagittal ankle kinematics were recorded for fifteen participants (10 females and 5 males, aged 37-64) with MS (EDSS 4-6) throughout the 6minWT. Ankle kinematics and temporal stride parameters were compared between the first and last 10 gait cycles of the 6minWT. Peak dorsiflexion in swing was significantly reduced at the end of the 6minWT compared to the start, with six of the fifteen participants having a decrease of two degrees or more. Statistically significant changes in temporal stride parameters suggested a decrease in walking speed. Our results suggest that with the protocol used in this study it is feasible to identify patients who experience increased foot drop as a result of a prolonged exercise task.

Short- and Long-Term Reliability of the 6-Minute Walk Test in People With Idiopathic Pulmonary Fibrosis.

The aim of this work was to investigate the short- and long-term test-retest reliability of the 6-min walk distance (6MWD), peak heart rate, and nadir oxygen desaturation in idiopathic pulmonary fibrosis (IPF). A reliability study of 70 adults with IPF was undertaken within out-patient pulmonary rehabilitation programs at 2 tertiary hospitals. Participants completed 2 baseline 6-min walk tests using a standard protocol, with continuous measures of percutaneous SpO2 and heart rate via pulse oximetry. The 6-min walk test was completed immediately following an intervention period and 6 months after. Reproducibility was assessed by intraclass correlation coefficient and Bland-Altman analysis. Participants with a mean ± SD diffusing capacity of the lung for carbon monoxide of 48 ± 14% were included. The reliability of the 6MWD was high (intraclass correlation coefficient = 0.96) with a mean learning effect of 21 m (95% CI 12-30 m). The learning effect persisted at 8 weeks (mean 14 m, 95% CI 5-23 m) but not 6 months (mean 15 m, 95% CI -1 to 30 m). Using the best (greatest) 6MWD significantly reduced the proportion of participants who were classified as having a clinically important response to rehabilitation compared with using the first 6MWD (40% vs 54%, P = .002). Nadir SpO2 was reproducible, with a mean difference of 0.7 ± 2.2%, and limits of agreement of -4 to 5%. Peak heart rate was more variable, with mean difference 5 ± 9 beats/min and limits of agreement of -12 to 20 beats/min. The 6MWD is a reproducible measure of exercise capacity in people with IPF. Whereas the nadir SpO2 may be accurately determined from one test, evaluating change in 6MWD with interventions may require 2 tests on each occasion. (ClinicalTrials.gov registration NCT0016828.).

Shorter Distance In 6-minute Walk Test In People With Multiple Sclerosis Demonstrating Leg Strength Asymmetries

One of the early signs of Multiple Sclerosis (MS) is weakness on one side of the body, which is experienced by more than 75% of people with MS (PwMS). In addition, up to 92% of PwMS are affected by fatigue. Our previous findings indicate that leg strength asymmetries are associated with imbalanced muscle activity during walking. PURPOSE: To determine the association between leg strength asymmetries and walking characteristics, as indicated by total distance covered and step count, during a 6-minute walk test in PwMS. METHODS: PwMS (aged 46-52 yrs) with self-reported asymmetries (2-5 on a 1-5 scale) and moderate disability (PDDS score 2-6) completed a series of maximal voluntary contractions of the knee extensors on each leg. Subsequently, participants walked as quickly, and safely as possible during a 6-minute walk test in a hallway with 2 cones placed 29 m apart. iPods with built-in accelerometers were strapped on both ankles to detect steps. In addition, ratings of perceived exertion (RPE) and distance covered were recorded every minute. Stride length was then calculated by dividing total distance by step count. RESULTS: The distance covered by the PwMS was 391 ± 110 m with 572 ± 86 steps. The average increase in stride length from minute 1 to minute 6 was 8 ± 4 %. The average difference in leg strength was 27 ± 12 %. The subject with the greatest leg strength asymmetry (37%) demonstrated the shortest distance during the 6-minute walk test (307 m) and the greatest change in stride length (12%). Furthermore, RPE and distance covered each minute remained constant during the 6 minutes. CONCLUSION: These preliminary data indicate that leg strength asymmetries may result in altered walking strategies during a 6-minute walking test in PwMS. While previous studies have used the 6-minute walking test as a measurement of fatigue, in this sample, fatigability, defined as a decline in performance over time, appears to rather manifest itself as changes in walking characteristics.

Gyroscopic corrections improve wearable sensor data prior to measuring dynamic sway in the gait of people with Multiple Sclerosis

Accelerometers are incorporated into many consumer devices providing new ways to monitor gait, mobility, and fall risk. However, many health benefits have not been realised because of issues with data quality that results from gravitational ‘cross-talk’ when the wearable device is tilted. Here we present an adaptive filter designed to improve the quality of accelerometer data prior to measuring dynamic pelvic sway patterns during a six minute walk test in people with and without Multiple Sclerosis (MS). Optical motion capture was used as the gold standard. Improved wearable device accuracy (≤4.4% NRMSE) was achieved using gyroscopic corrections and scaling filter thresholds by step frequency. The people with MS presented significantly greater pelvis sway range to compensate for their lower limb weaknesses and joint contractures. The visualisation of asymmetric pelvic sway in people with MS illustrates the potential to better understand their mobility impairments for reducing fall risk.

Reliability and Validity of Dual-Task Mobility Assessments in People with Chronic Stroke.

BackgroundThe ability to perform a cognitive task while walking simultaneously (dual-tasking) is important in real life. However, the psychometric properties of dual-task walking tests have not been well established in stroke.ObjectiveTo assess the test-retest reliability, concurrent and known-groups validity of various dual-task walking tests in people with chronic stroke.DesignObservational measurement study with a test-retest design.MethodsEighty-eight individuals with chronic stroke participated. The testing protocol involved four walking tasks (walking forward at self-selected and maximal speed, walking backward at self-selected speed, and crossing over obstacles) performed simultaneously with each of the three attention-demanding tasks (verbal fluency, serial 3 subtractions or carrying a cup of water). For each dual-task condition, the time taken to complete the walking task, the correct response rate (CRR) of the cognitive task, and the dual-task effect (DTE) for the walking time and CRR were calculated. Forty-six of the participants were tested twice within 3–4 days to establish test-retest reliability.ResultsThe walking time in various dual-task assessments demonstrated good to excellent reliability [Intraclass correlation coefficient (ICC2,1) = 0.70–0.93; relative minimal detectable change at 95% confidence level (MDC95%) = 29%-45%]. The reliability of the CRR (ICC2,1 = 0.58–0.81) and the DTE in walking time (ICC2,1 = 0.11–0.80) was more varied. The reliability of the DTE in CRR (ICC2,1 = -0.31–0.40) was poor to fair. The walking time and CRR obtained in various dual-task walking tests were moderately to strongly correlated with those of the dual-task Timed-up-and-Go test, thus demonstrating good concurrent validity. None of the tests could discriminate fallers (those who had sustained at least one fall in the past year) from non-fallers.LimitationThe results are generalizable to community-dwelling individuals with chronic stroke only.ConclusionsThe walking time derived from the various dual-task assessments generally demonstrated good to excellent reliability, making them potentially useful in clinical practice and future research endeavors. However, the usefulness of these measurements in predicting falls needs to be further explored. Relatively low reliability was shown in the cognitive outcomes and DTE, which may not be preferred measurements for assessing dual-task performance.

Repeatability of the endurance shuttle walk test in people with chronic obstructive pulmonary disease.

Walking tests, including the endurance shuttle walk test (ESWT), have been used to assess functional capacity in people with chronic obstructive pulmonary disease (COPD). Learning effects through repeated practice have been reported for some field walking tests. However, the repeatability of ESWT at various time points, i.e. within the same day, within the week and one week apart, has not been examined. This study aimed to evaluate the repeatability of ESWT overtime to determine whether or not a learning effect existed. Twenty-two participants diagnosed with COPD [age 71 ± 6 years; FEV1 % predicted 54 ± 24%] were recruited. Participants performed two incremental shuttle walk tests to determine the walking speed for the ESWT and a practice ESWT (Ep ) to determine whether the ESWT level was appropriate. ESWT 1(E1 ) and ESWT 2(E2 ) were performed on the same day, 30 min apart; ESWT 3(E3 ) was performed within a week from E2 ; ESWT 4(E4 ) was performed one week after E3 . Duration walked in each ESWT was recorded. The repeatability of the four ESWTs was analyzed using repeated measures analysis of variance. The mean durations of E1 to E4 were 368 ± 203 s, 371 ± 182 s, 386 ± 213 s and 367 ± 223 s, respectively, with no time effect (F=0.18, P=0.79). There was no evidence of learning effect when ESWT was repeated within one day, within one week and one week apart, once the appropriate baseline level was established, showing that ESWT is repeatable in people with moderate COPD.