The Călimani-Gurghiu-Harghita volcanic range (CGH) represents the surface manifestation of the post-collisional magmatism that followed the docking of its basement, the Dacia Mega Unit, onto the East European margin. Between ca. 11 and 0.3 Ma, detachment of subducted slab, magma generation, and volcanic activity in CGH propagated south-southeastward, sub-parallel with the collisional Eastern Carpathian Orogen, resulting in the construction of a series of mostly composite volcanoes dominated by calc-alkaline lavas and pyroclastic products. The generally well-preserved axial row of the CGH volcanic edifices is accompanied by voluminous volcaniclastic deposits of which sources and emplacement history persist as a matter of debate. In the standard view reflected in regional scale geologic maps, these deposits represent products of complete erosion of hypothetical earlier volcanoes. Other interpretation, however, suggest that they are at least partially constituted by voluminous volcanic debris avalanche deposits (VDADs).By combining evidence from field observation and GIS analysis with published and new data from petrography, bulk-rock geochemistry, and K/Ar geochronology, here we demonstrate that VDADs vastly dominate these volcanoclastic deposits. In addition to two previously identified VDADs (Western Călimani and Vârghiş), we show that further six VDADs (Eastern Călimani, Fâncel-Lăpuşna, Ostoroş, Ivo-Cocoizaş, Luci, and Pilişca) were generated due to the sector failure of a series of CGH volcanoes, most of which still preserve well-distinguishable collapse scars. Based on our estimates, debris avalanches with volumes between <1 km3 and > 100 km3 displaced 0.4–39% of the source edifices, transferring nearly a third of their cumulated volcanic output to the observed volcaniclastic deposits.K/Ar age constraints suggest VDAD formation closely followed in space and time the migrating volcanic activity between ca. 7.8 and 1.5 Ma. Relying on this age pattern, collapse scar orientations, and VDAD runout directions, we propose that regional scale deformation of the Dacia lithosphere imposed by progressive detachment of the underlying subducted slab, manifested on the surface as a transient subsidence–uplift couple traveling along CGH as well as opening of intramountain basins at the eastern flank of the range, was responsible for basement tilting and faulting that destabilised the CGH volcanic edifices. Seismic activity associated with slab detachment and shallow crustal fault system as well as explosive volcanic eruptions may have triggered the collapse of these edifices, leading to the generation of the VDADs.