In South Korea, an apartment house is one of the most common types of residence. It causes discomfort to the residents and has made lots of social issues due to sharing the facilities. Especially, the interlayer noise caused by children’s running, which is classified as heavy weight impact sound, has become a major cause of conflicts between neighbors. In this study, a void slab system has been proposed to reduce the interlayer noise caused by heavy weight impact sound and compared to a typical wall system by means of characteristics of vibration and noise performance. Three specimens of multi-span slab system, based on the typical wall and the void slab system, have been built. Experiments for with and without resilient layer in both slab systems were carried out using a standard heavy weight impact source. The single number quantity was evaluated specified in the KS F 2863-2. The single number quantity for the wall system with and without the resilient layer was 3dB and 10dB higher than that of the void slab system, respectively. Finally, it has been confirmed that the proposed void slab system is more effective than the typical wall system in reducing interlayer noise problem.