The present study compares the career‐related interests and values of Asian‐American and Caucasian‐American college students and explores the relationships among career interests, perceived control, and acculturation. Career‐related interests were defined by Holland's (1959, 1985a) model of vocational personality types and work environments, and career‐related values were defined by Schein's (1987) career anchors. The Career Anchor Inventory (Nordvik, 1991), the Self‐Directed Search (Holland, 1991), and the Spheres of Control Scale (Paulhus & Van Selst, 1990), were completed by 184 Asian‐American and 130 Caucasian‐American undergraduate students. The Asian‐Americans also completed the Suinn‐Lew Asian Self‐Identity Acculturation Scale (Suinn, Rickard‐Figueroa, Lew & Vigil, 1987). In comparison to Caucasian‐American students, Asian‐American students showed higher interest in the Investigative and Conventional vocational categories, but lower interest in the Social category. Asian‐American subjects were lower in perceived control in the Personal and Interpersonal spheres. Among the Asian‐Americans, acculturation was positively correlated with perceived control in the Personal and Interpersonal spheres and with the Enterprising vocational category. Acculturation was negatively correlated with Investigative and Conventional interests.