Vitreous Glucose Research Articles

Observations on the Reducing Substances (Glucose) of the Aqueous and Vitreous Humors of the Eye

In the fasting rabbit under dial anesthesia the glucose values were: aqueous 164 mg. percent, vitreous 104 mg. percent, venous blood 137 mg. percent, arterial blood 158 mg. percent. The aqueous glucose followed closely fluctuations in the blood glucose. The vitreous glucose did not follow so closely the rise and fall of the blood glucose. Operative procedures used to relieve intraocular hypertension produced no significant alterations in the glucose values of the aqueous or vitreous. Adrenaline, eserine, or atropine applied locally to the eye produced material changes in the rate of diffusion of glucose between the blood, aqueous, and vitreous. Changes in the intraocular pressure were recorded with alterations of the blood glucose. In the normal eye no significant changes in intraocular pressure were noted following the local application of atropine, eserine, or acetylcholine. Various types of mechanical irritation of the uveal bed were followed by prompt increases in intraocular pressure. From the Department of Ophthalmology, Washington University School of Medicine. Read before the Association for Research in Ophthalmology at Kansas City, Missouri, May 12, 1936. In the fasting rabbit under dial anesthesia the glucose values were: aqueous 164 mg. percent, vitreous 104 mg. percent, venous blood 137 mg. percent, arterial blood 158 mg. percent. The aqueous glucose followed closely fluctuations in the blood glucose. The vitreous glucose did not follow so closely the rise and fall of the blood glucose. Operative procedures used to relieve intraocular hypertension produced no significant alterations in the glucose values of the aqueous or vitreous. Adrenaline, eserine, or atropine applied locally to the eye produced material changes in the rate of diffusion of glucose between the blood, aqueous, and vitreous. Changes in the intraocular pressure were recorded with alterations of the blood glucose. In the normal eye no significant changes in intraocular pressure were noted following the local application of atropine, eserine, or acetylcholine. Various types of mechanical irritation of the uveal bed were followed by prompt increases in intraocular pressure. From the Department of Ophthalmology, Washington University School of Medicine. Read before the Association for Research in Ophthalmology at Kansas City, Missouri, May 12, 1936.