Vitreous Cyst Research Articles

Surgical treatment and histopathology of a symptomatic free-floating primary pigment epithelial iris cyst in the anterior vitreous

We report the surgical removal of an iris pigment epithelial cyst that was floating freely in the posterior chamber of an 18-month-old child. The reason for surgical removal was disturbance in near vision secondary to the movement of the cyst across the visual axis. Visual disturbance secondary to a unilateral anterior vitreous iris cyst at this age is a rare presentation and, to the best of our knowledge, has not been reported previously as an indication for surgery. We performed histopathological study of the cyst aspirate to determine its contents and its possible origin.

Cisto vítreo e retinose pigmentária: relato de caso

Vitreous cyst is a rare condition of the posterior segment of the eye. It can occur in eyes with coexistent ocular diseases or in eyes that are otherwise normal. This study reports a case of vitreous cyst in a patient with retinitis pigmentosa and presents its clinical and ultrasonographic features.

Argon Laser Photocystotomy of a Vitreous Cyst.

Free-floating idiopathic vitreous cysts are rare entities. For symptomatic patients, treatment options include laser photocystotomy or pars plana vitrectomy (PPV) with cyst excision. Historically, size of the cyst impacted treatment approaches. Laser treatments have been used for smaller cysts ranging 3 to 5 mm in diameter. PPV has been utilized for cysts larger than 4 mm. Successful laser photocystotomy has been reported, utilizing both argon and Nd: YAG lasers. Herein, we present a case of successful argon laser photocystotomy of a 7.1 mm diameter vitreous cyst, the largest documented cyst ever treated. Treatment should be individualized based on patient age, ability to cooperate in an office setting, phakic status, status of the posterior hyaloid, cyst morphology, and location. In our case, because of pigment on the anterior cyst surface, and the presence of an attached posterior hyaloid, the argon green laser was used.

Six-year dynamic growth pattern of two concentric congenital vitreous cysts

Six-year dynamic growth pattern of two concentric congenital vitreous cysts

Posterior vitreous cyst and intermediate uveitis

Posterior vitreous cyst and intermediate uveitis

Histologic and immunohistochemical features of a vitreous cyst.

To report the histologic and immunohistochemical features of a congenital vitreous cyst. Interventional case report with immunohistochemical correlation. A 58-year-old woman with known vitreous cyst since childhood had an enlarging visual floater. The vitreous cyst was removed by pars plana vitrectomy and central vision was restored. Pathology confirmed a vitreous cyst derived from neural and glial tissue and consistent with retinal origin. Congenital vitreous cysts, derived from neural and glial tissue, can be safely removed using pars plana vitrectomy.

Idiopathic pigmented free-floating posterior vitreous cyst

A 28-year-old female who complained of visual symptoms in the right eye was admitted to the ophthalmology clinic. She had been suffering from visual disturbance for about 5 years and her symptoms had become worse during the last 2 months. There was no previous history of trauma, infection or inflammatory disorders. A pigmented vitreous cyst was detected in her ophthalmologic examination. As the patient refused, laser cystotomy could not be performed. The pigmented vitreous cyst was possibly congenital in origin and described as a cystic choristoma from the primitive hyaloid system in the literature. The movements of the cyst, causing only transient blurring of vision, may rarely affect the visual axis. The visual acuity was 20/20 in the affected eye so it was suggested that she should be followed-up periodically for her cyst.

Pigmented Free-Floating Vitreous Cyst in a Child

An 8-year-old asymptomatic boy was referred for a pigmented fundus lesion in his left eye that was suspected to be a possible choroidal melanoma. Visual acuity was 20/20 in each eye. Ocular examination in the upright position revealed a pigmented lesion measuring 4 mm in diameter and 3 mm in thickness located inferior to the fovea. Following supine positioning, the mass floated to the superior macular region. UI-trasonography confirmed a cystic vitreous mass. Observation of the benign vitreous cyst was advised. A free-floating pigmented cyst can resemble a pigmented intraocular tumor, particularly if it is immediately preretinal.

Free-Floating Unilateral Pigmented Vitreous Cyst in a Child

Free-floating vitreous cysts have been ocular curiosities, especially in children. Various etiologies have been proposed. Most of these cysts are asymptomatic except for subtle symptoms of visual floaters. When the visual axis is obscured, treatment options include surgery and laser treatment. We report a case of a unilateral pigmented vitreous cyst in a child.

Clinical features, histopathological analysis and surgical treatment of a free floating vitreous cyst: a case report

The authors present a report of a 44-year-old female patient, with complaints of visual disturbances in the left eye. The symptoms were present for at least 5 years and worsened in the last 2 years, impairing her activities. The patient reported perception of a floating circle, which blurred her vision. There was no previous history of trauma, infectious or inflammatory disease. Clinical evaluation included physical examination, laboratory testing, abdominal ultrasonography, thorax X-ray and head tomography. Ophthalmologic examination consisted of visual acuity, motility tests, biomicroscopy, tonometry and indirect ophthalmoscopy. Complementary investigation was done with a and b scan ocular ultrasonography. The chosen therapeutic approach to excise the cyst was pars plana vitrectomy, successfully performed. Anatomopathologic analysis revealed a pigmented vitreous cyst, of possible congenital origin, described as a cystic choristoma from the primitive hyaloid system. Benign evolution, clinical findings and histopathological analysis corroborated the diagnostic hypothesis of a cystic choristoma of the primitive hyaloid system. Surgery (pars plana vitrectomy) was successful and the patient returned with visual acuity of 20/20 in both eyes, and with no further complaints.

Nd:YAG Laser Photocystotomy of a Free-Floating Pigmented Anterior Vitreous Cyst

An 8-year-old girl presented with a free-floating pigmented cyst in the anterior vitreous causing a large, visually disturbing floater. A simple laser photocystotomy with a single-frequency Nd:YAG laser resulted in a reduction in the size of the cyst but persistence of the floater. An attempt at further laser fragmentation of the cyst resulted in iatrogenic cataract formation.

Treatment and histopathology of a congenital vitreous cyst

Objective This study aimed to evaluate the treatment efficacy of a congenital vitreous cyst and to examine the cyst histopathologically to determine its cellular makeup and possible origin. Study design The study design was a case report, including a clinicopathologic correlation. Intervention A 35-year-old woman with a known vitreous cyst since childhood became increasingly troubled by its symptoms. The cyst was treated initially with argon laser photocoagulation. Vitrectomy subsequently was performed because the deflated cyst remained near the visual axis. Histopathologic studies included light and electron microscopy; immunocytochemistry for actin and glial fibrillary acidic protein (GFAP); and enzyme histochemistry for carbonic anhydrase (CA). Results The cyst was composed of a single layer of heavily pigmented cells with a thick basement membrane along the internal borders of the cells. Ultrastructurally, the cells were connected with tight junctions, had microvillous processes at their apices, and contained numerous large melanosomes in various stages of maturity, including premelanosomes. Immunochemistry showed the cells were positive for actin but negative for GFAP. Enzyme histochemical staining for CA also was strongly positive. Conclusions The confinement of this cyst to the region of Cloquet’s canal, the presence of a Mittendorf’s dot, the cyst’s existence for many years, and the finding of pigment epithelial-type cells having immature melanosomes (a feature not seen after birth in normal pigment epithelium) lead the authors to believe that this cyst was a congenital remnant of the primary hyaloidal system. Because pigmented cells are not normally present in this part of the eye, the cyst was a choristoma of the primary hyaloidal system.

Pigmented Vitreous Cyst

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Excentric lentiglobus posterior

The posterior lentiglobe is a rare anomaly of the lens shape. Two cases of excentric protuberance of the posterior capsule are presented. To our knowledge, only one description of a similar case exists so far. An eight-year-old girl (diagnosis by routine examination, V.A. 20/20) and a six-year-old boy (V. A. 20/200, esotropia) are presented. Apart from a persistent hyperplastic primary vitreous and a posterior pole cataract a vitreous cyst adherent to the posterior surface of the lens has to be considered as differential diagnosis. The etiology remains unclear. In excentric posterior lengtiglobe a good vision is possible. However, if visual acuity is impaired by posterior pole opacity or distortion of the spherical surface, removal of the lens followed by optical correction (contact lens, intraocular lens) of aphakia should be performed.

Posterior Vitreous Cyst

We observed two patients who had unilateral posterior vitreous cysts; one patient had been observed for 17 years. Both patients were young females who reported transient, infrequent obscurations of vision that were not disabling. One involved eye was emmetropic, and the other was highly myopic. No other ocular abnormalities were present. In the patient observed for 17 years, the physical characteristics of the posterior vitreous cyst remained unchanged. With this stable clinical course, posterior vitreous cyst that does not visually disable the patient may be managed by periodic observation.

Biomicroscopy and Argon Laser Photocystotomy of Free-Floating Vitreous Cysts

Laser photocystotomy is a new technique that employs a 200 μ beam of argon laser at a setting of 0.1 second and 500 mW to accomplish cystotomy of symptomatic free-floating vitreous cysts. It was successful in treating this type of cyst in the right eye of a 23-year-old man. The paper also includes the first photographic documentation of the biomicroscopic features of a free-floating vitreous cyst.

Pigmented Free-floating Vitreous Cysts in Two Young Adults: Electron Microscopic Observations

Pigmented free-floating vitreous cysts were observed in two young adults. In both patients, the cyst was in the visual axis; however, the size and extent of pigmentation of the cyst wall compromised the visual acuity only in case 1. In this case, the vitreous cyst was aspirated through the pars plana and studied by light and electron microscopy. Histopathologically, the cyst was lined by a heavily pigmented layer of cuboidal cells intermixed with sheets of nonpigmented cells forming papillae. Ultrastructurally, the pigmented cells contained predominantly large, mature melanosomes (0.9–2.2 μm). Scattered immature melanosomes with a scarcity of mitochondria and other cytoplasmic organelles were present. Additionally, the cells were invested by a thin polarized basement membrane and displayed apical microvilli. Numerous microvillous processes were noted under the plasmalemmae and between adjacent cells. The results of the light and ultrastructural studies provide support for the hypothesis that the cyst in case 1 originated from the pigment epithelium. The possibility of a traumatic etiology is proposed for these pigmented vitreous cysts. If significant visual impairment is present, surgical removal of the cyst through a pars plana approach can be safely performed as in our case 1.

A Free-Floating Vitreous Cyst in the Otherwise Normal Eye of a Young Man

A Free-Floating Vitreous Cyst in the Otherwise Normal Eye of a Young Man

Multiple Free Floating Vitreous Cysts with Congenital Nystagmus and Esotropia

Multiple Free Floating Vitreous Cysts with Congenital Nystagmus and Esotropia

Mobile vitreous cysts.

Mobile vitreous cysts.