Vitamin D And Omega-3 Trial Research Articles

Vitamin D and Cancer: Uncertainty Persists; Research Continues

The VITAL Trial Amid the many studies under way is a newly launched, large multicenter trial called VITAL (Vitamin D and Omega-3 Trial), investigating whether high doses of vitamin D and the omega-3 fatty acids found in fi sh oil can reduce the risk of developing cancer, heart disease, and stroke. Primary outcomes are incidence of these diseases after 5 years. VITAL is the fi rst large-scale randomized trial designed to test vitamin D’s role in preventing cancer and cardiovascular disease, Manson said. The trial is testing a higher dose of vitamin D than most previous studies and is “large enough to provide conclusive results.”

Vitamin D and the heart: Why we need large-scale clinical trials

Although vitamin D supplementation appears to be a promising intervention for reducing risks of cancer, cardiovascular disease, and other chronic diseases, existing evidence on its benefits and risks is limited and inconclusive. Recruitment is now under way for the Vitamin D and Omega-3 Trial (VITAL), the first large-scale randomized clinical trial of these nutritional agents for the primary prevention of cancer and cardiovascular disease.