AbstractWe found insufficient evidence to conclude that seminatural treatment (SNT; i.e., rearing in camouflage‐painted raceways with surface and underwater structures and underwater feeders) of juvenile Chinook salmon Oncorhynchus tshawytscha resulted in higher survival indices than did optimum conventional treatment (OCT; i.e., rearing in concrete raceways with surface feeding) for the specific treatments and environmental conditions tested. We reared spring Chinook salmon from fry to smolt in paired raceways under the SNT and OCT rearing treatments for five consecutive years. For four to nine SNT and OCT raceway pairs annually, we used passive integrated transponder, coded wire, and visual implant elastomer tags to compare survival indices for juvenile fish from release at three different acclimation sites 340‐400 km downstream to passage at McNary Dam on the Columbia River, and for adults from release to adult return to Roza Dam in the upper Yakima basin. The observed differences in juvenile and adult survival between the SNT and OCT fish were either statistically insignificant, conflicting in their statistical significance, or explained by significant differences in the presence of the causative agents of bacterial kidney disease in juvenile fish at release.