s1 May 1966Direct Observation of Induced Intravascular Thromboembolic Phenomena in the Living Extracorporeal Eye.Arthur J. Seaman, M.D., F.A.C.P., C. Lawrence Lutcher, M.D., Charlotte Mofft, Bonita HueberArthur J. Seaman, M.D., F.A.C.P.Search for more papers by this author, C. Lawrence Lutcher, M.D.Search for more papers by this author, Charlotte MofftSearch for more papers by this author, Bonita HueberSearch for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-64-5-1163_2 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptA new experimental technique, the living extracorporeal eye (Seaman and associates: Clin. Res. 13: 138, 1965 (Abstract); Scand. J. Clin. Lab. Invest. Supplement 84, 17: 101, 1965) is used to study blood flow and thromboembolic phenomena. Bovine eyes are enucleated immediately after slaughter. The ciliary artery is catheterized. The retinal circulation is cleared with modified Krebs' solution. Perfusion with compatible oxygenated human or bovine blood is commenced and recorded with still and cinephotography.Upon addition of adenosine diphosphate to the heparinized arterial inflow, grossly visible platelet aggregates appear. These visible emboli impede flow and may adhere to the intima. They... This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Portland, Oregon PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 May 1966Volume 64, Issue 5Page: 1163-1163KeywordsAdenosine diphosphateArteriesBloodBlood flowPlatelets Issue Published: 1 May 1966 PDF DownloadLoading ...