Virtual Reality Head-mounted Display Research Articles

Change in Blink Rate in the Metaverse VR HMD and AR Glasses Environment.

Blink rate, a major physiological response in humans, directly affects ocular diseases such as keratitis and dry eye. The blink rate in normal eyes appears at a constant frequency of 6–30 times per minute and is constant for each individual. In a previous study, the blink rate decreased when viewing content with high intensity and realism. Therefore, we tried to investigate the change in blink rate when viewing the content in VR HMD (virtual reality head-mounted display) and AR (augmented reality) glasses environments. We compared and analyzed the blink rate in four environments: natural state, viewing monitor, viewing VR HMD, and viewing AR glasses. Twenty-one participants (age, 26.87 ± 3.31 years) viewed the content for 1 min in four environments. One-way repeated ANOVA was used to analyze the blink rate changes. The study showed that the blink rate was decreased in the monitor, VR HMD, and AR glasses environments compared to that in the natural environment. Comparing the VR HMD environment with the AR glasses environment showed that the blink rate decreased in the VR HMD environment. The results of this study can be used for content use safety recommendations (guidelines for safe use of contents due to decreased blink rate) in the VR HMD and AR glasses environments, which are currently attracting attention in the metaverse.

Stabilization of spherical videos based on feature uncertainty

Nowadays the trend is to acquire and share information in an immersive and natural way with new technologies such as Virtual Reality (VR) and 360^{circ } video. However, the use of 360^{circ } video, even more the use of VR head-mounted display, can generate general discomfort (“cybersickness”) and one factor is the video shaking. In this work, we developed a method to make the viewing of 360^{circ } video smoother and more comfortable to watch. First, the rotations are obtained with an innovative technique using a Particle Swarm Optimization algorithm considering the uncertainty estimation among features. In addition, a modified Chauvenet criterion is used to find and suppress outliers features from the algorithm. Afterward, a time-weighted color filter is applied to each frame in order to handle also videos with small translational jitter, rolling shutter wobble, parallax, and lens deformation. Thanks to our complete offline stabilization process, we achieved good-quality results in terms of video stabilization. Achieving better robustness compared to other works. The method was validated using virtual and real 360^{circ } video data of a mine environment acquired by a drone. Finally, a user study based on a subjective and standard Simulator Sickness Questionnaire was submitted to quantify simulator sickness before and after the stabilization process. The questionnaire underlined alleviation of cybersickness using stabilized videos with our approach

Experience prototyping through virtual reality head-mounted displays: Design appraisals of automotive user interfaces

This paper investigates virtual reality head-mounted displays (VR-HMDs) as immersive and interactive media to simulate how new automotive user interfaces will contribute to passengers’ user experience (UX) through experience prototyping of a conceptual infotainment system for front-seat passengers. It first demonstrates the integration of VR-HMDs into experience prototypes through (1) identification of what to prototype by deconstructing the system into its aspects; (2) definition of the scope and fidelity of the prototype for each design aspect; and (3) elimination of challenges brought by VR-HMD (e.g. simulation sickness) through strategies like static presentation of car surroundings. Secondly, it confirms the strategies to exploit immersion safely with the results of the simulation sickness and presence questionnaires. Thirdly, it probes how using VR-HMD affects UX appraisals with content analysis of the follow-up interviews. The paper concludes with a discussion of how VR-HMDs enrich digital appraisals of (automotive) user interfaces at early design stages.

A Stray Light Detection Model for VR Head-Mounted Display Based on Visual Perception

In recent years, the general public and the technology industry have favored stereoscopic vision, immersive experience, and real-time visual information reception of virtual reality (VR) and augmented reality (AR). The device carrier, the Head-Mounted Display (HMD), is recognized as one of the next generation’s most promising computing and communication platforms. HMD is a virtual image optical display device that combines optical lens modules and binocular displays. The visual impact it brings is much more complicated than the traditional display and also influences the performance of image quality. This research investigated the visual threshold of stray light for three kinds of VR HMD devices, and proposes a qualitative model, derived from psychophysical experiments and the measurement of images on VR devices. The recorded threshold data of the psychophysical stray light perception experiment was used as the target when training. VR display image captured by a wide-angle camera was processed, through a series of image processing procedures, to extract variables in the range of interest. The machine learning algorithm established an evaluation method for human eye-perceived stray light in the study. Four supervised learning algorithms, including K-Nearest Neighbor (KNN), Logistic Regression (LR), Support Vector Machine (SVM), and Random Forest (RF), were compared. The established model’s accuracy was about 90% in all four algorithms. It also proved that different percentages of thresholds could be used to label data according to demand to predict the feasibility of various subdivision inspection specifications in the future. This research aimed to provide a fast and effective stray light qualitative evaluation method to be used as a basis for future HMD optical system design and quality control. Thus, stray light evaluation will become one of the critical indicators of image quality and will be applicable to VR or AR content design.

Analgesic and Anxiolytic Effects of Virtual Reality During Minor Procedures in an Emergency Department: A Randomized Controlled Study

We aimed to assess the analgesic and anxiolytic efficacy of distraction, a nonpharmacologic intervention provided by 3-dimensional (3D) virtual reality (VR) compared with that provided by 2-dimensional (2D) VR during minor emergency department (ED) procedures. This randomized controlled study conducted in the ED of a teaching hospital included patients aged more than or equal to 18 years undergoing minor procedures. The patients watched the same computer-generated VR world either in 3D in a head-mounted display (intervention) or in 2D on a laptop screen (control). Our main outcomes were pain and anxiety during the procedure, assessed on a 100-mm visual analog scale. Secondary outcomes included the impression of telepresence in the computer-generated world assessed using the Igroup Presence Questionnaire, and the prevalence and intensity of cybersickness measured on a 100-mm visual analog scale. The final analysis included 117 patients. The differences in median procedural pain and anxiety levels between the 2D and 3D VR groups were not significant:-3 mm (95% confidence interval [CI]-14 to 8) and-4 mm (95% CI-15 to 3), respectively; the difference in telepresence was 2.0 point (95% CI 0 to 2.0), and the proportion difference of cybersickness was-4% (95% CI-22 to 14), with an intensity difference of-5 mm (95% CI-9 to 3). During minor procedures in adult patients in the ED, distraction by viewing a 3D virtual world in a head-mounted VR display did not result in lower average levels of procedural pain and anxiety than that by 2D viewing on a screen despite a higher sense of telepresence. There were no significant differences in the prevalence and intensity of cybersickness between the 2 groups.

The Effects of Virtual Reality Nonphysical Mental Training on Coordination and Skill Transfer in Healthy Adults

Mental training is a promising method to improve motor skills. However, transfer of these improvements to different skills or functional activities is still unclear. The purpose of this study was to investigate the effects of mental balance training programs on motor coordination and skill transfer. Randomized controlled trial. Fifty-seven healthy adults (28 females and 29 males) aged between 18 and 25years participated in this study. Participants were randomly assigned to 3 groups: virtual reality (VR) mental training group, conventional mental training group, and control group. The training program included action observation and motor imagery practice with balance exercise videos. The VR mental training group trained with a VR head-mounted display and the conventional mental training group trained with a nonimmersive computer monitor for 30 minutes, 3 days per week, for 4 weeks. Coordination skills were tested with 2 separate custom-made obstacle course tests (OCT-1 and OCT-2). OCT tests included crouching, turning, leaning, stepping over, changing direction, walking on various surfaces, or using repeated hand and arm movement tasks. OCT-1 was used to investigate the effects of mental exercises on coordination skills, and OCT-2 to investigate transfer effects for novel tasks. Test time (total and corrected) and error types (minor, major, and total) were recorded. Touching an obstacle without changing its position was classified as a minor error, and changing its position was a major error. OCT-1 test time and number of errors significantly decreased in the VR mental training and conventional mental training groups, but not in the control group. The number of minor errors was only decreased in the VR mental training group. For OCT-2, total and corrected time were not significantly different between the groups. However, both training groups were significantly superior to the control group for all types of errors. Our findings suggest that both training interventions can significantly improve coordination and skill transfer test results. In addition, VR mental training may have some advantages over conventional mental training. These findings are promising for the use of mental training for prevention and rehabilitation in special populations.

Omnidirectional Galvanic Vestibular Stimulation in Virtual Reality.

In this paper we propose omnidirectional galvanic vestibular stimulation (GVS) to mitigate cybersickness in virtual reality applications. One of the most accepted theories indicates that Cybersickness is caused by the visually induced impression of ego motion while physically remaining at rest. As a result of this sensory mismatch, people associate negative symptoms with VR and sometimes avoid the technology altogether. To reconcile the two contradicting sensory perceptions, we investigate GVS to stimulate the vestibular canals behind our ears with low-current electrical signals that are specifically attuned to the visually displayed camera motion. We describe how to calibrate and generate the appropriate GVS signals in real-time for pre-recorded omnidirectional videos exhibiting ego-motion in all three spatial directions. For validation, we conduct an experiment presenting real-world 360° videos shot from a moving first-person perspective in a VR head-mounted display. Our findings indicate that GVS is able to significantly reduce discomfort for cybersickness-susceptible VR users, creating a deeper and more enjoyable immersive experience for many people.

The Effects of Virtual Reality Nonphysical Mental Training on Balance Skills and Functional Near-Infrared Spectroscopy Activity in Healthy Adults.

Athletic skills such as balance are considered physical skills. However, these skills may not just improve by physical training, but also by mental training. The purpose of this study was to investigate the effects of mental training programs on balance skills and hemodynamic responses of the prefrontal cortex. Randomized controlled trial. Fifty-seven healthy adults (28 females, 29 males), aged between 18-25 years, participated in this study. Participants were randomly assigned to 3 groups: virtual reality mental training (VRMT) group, conventional mental training (CMT) group, and control group. The training program included action observation and motor imagery practices with balance exercise videos. The VRMT group trained with a VR head-mounted display, while the CMT group trained with a non-immersive computer screen, for 30 minutes, 3 days per week for 4 weeks. At baseline and after 4 weeks of training, balance was investigated with stabilometry and Star Excursion Balance Test (SEBT). Balance tests were performed with simultaneous functional near-infrared spectroscopy (fNIRS) imaging to measure prefrontal cortex oxygenation. For the stabilometry test, at least 1 variable improved significantly in both VRMT and CMT groups but not in the control group. For SEBT, composite reach distance significantly increased in both VRMT and CMT groups but significantly decreased in the control group. For separate directional scores, reach distance was significantly increased in both mental training groups for nondominant leg posterolateral and posteromedial directions, and dominant leg posterolateral direction, while nondominant posteromedial score was significantly increased only in the VRMT group. Between-group comparisons showed that dominant leg posteromedial and posterolateral score improvements were significantly higher than control group for both mental training groups, while nondominant leg improvements were significantly higher than control group only for the VRMT group. The fNIRS oxyhemoglobin levels were not significantly changed during stabilometry tests. However, oxyhemoglobin levels significantly reduced only in the control group during SEBT. Our findings suggest that both mental training interventions can significantly improve balance test results. Additionally, VRMT may have some advantages over CMT. These findings are promising for the use of mental training in prevention and rehabilitation for special populations such as athletes and older adults.

Acceptance by athletes of a virtual reality head-mounted display intended to enhance sport performance

While a growing number of studies have highlighted the potential of virtual reality (VR) to improve athletes’ skills, no research has yet focused on acceptance of a VR head-mounted display (VR-HMD) designed to increase sport performance. However, even if technological devices could potentially lead to performance improvement, athletes may not always accept them. To investigate this issue, the Technology Acceptance Model (TAM) examines if perceived usefulness, perceived ease of use, perceived enjoyment, and subjective norms (i.e., social influence) are positive predictors of intention to use a specific technology. The aims of the present study were to test with competitive athletes the validity of the TAM before a first use of a VR-HMD intended to enhance sport performance and to examine to what extent the level of practice and the type of sport practiced have an influence on the previous variables of the TAM. The study sample comprised 1162 French athletes (472 women, 690 men, Mage = 24.50 ± 8.51 years) who usually practiced a sport in competition (from recreational to international level). After reading a short text presenting the VR-HMD and its interests for sport performance, the participants filled out an online questionnaire assessing their acceptance of this technological device before a first use. The results of the structural equation modeling analysis revealed that perceived usefulness, perceived ease of use, perceived enjoyment, and subjective norms were positive predictors of intention to use this VR-HMD, validating the suitability of the TAM for investigating the acceptance by athletes of a VR-HMD designed to increase their sport performance. The results also showed that athletes of all sport levels (a) had a significant intention to use VR, (b) found it quite useful (except for recreational athletes), quite easy to use, and quite pleasant to use, even if their entourage would not encourage them to use it (except for international athletes), and (c) found the VR-HMD easy and pleasant to use whatever the sport practiced. Notably some athletes (e.g., triathletes, swimmers, cyclists) did not find the VR-HMD significantly useful and did not have significant intention to use it to increase their performance. Identifying acceptance by athletes of such a device may increase the likelihood that it will be used by athletes of different levels and from different sports, so that they can benefit from all its advantages related to the improvement of their sport performance. Needs-based targeted interventions may also be conducted toward athletes who might be reluctant to integrate this type of device into their training.

Understanding, Addressing, and Analysing Digital Eye Strain in Virtual Reality Head-Mounted Displays

Digital eye strain (DES), caused by prolonged exposure to digital screens, stresses the visual system and negatively affects users’ well-being and productivity. While DES is well-studied in computer displays, its impact on users of virtual reality (VR) head-mounted displays (HMDs) is largely unexplored—despite that some of their key properties (e.g., the vergence-accommodation conflict) make VR-HMDs particularly prone. This work provides the first comprehensive investigation into DES in VR HMDs. We present results from a survey with 68 experienced users to understand DES symptoms in VR-HMDs. To help address DES, we investigate eye exercises resulting from survey answers and blue light filtering in three user studies (N = 71). Results demonstrate that eye exercises, but not blue light filtering, can effectively reduce DES. We conclude with an extensive analysis of the user studies and condense our findings in 10 key challenges that guide future work in this emerging research area.

Virtual Reality Based Guided Meditation for Patients with Opioid Tolerance and Opioid Use Disorders

BackgroundThe management of acute pain in patients with pre-existing opioid tolerance or opioid use disorders presents unique challenges. In light of the concerns regarding opioid use, safe and effective alternatives to opioid medications are of increasing interest. AimsThis study was conducted to determine if the use of guided meditation delivered through immersive virtual reality can reduce pain in patients with opioid tolerance or opioid use disorders, including opioid abuse or opioid dependence. DesignA quasi-experimental pre-test and post-test study design was used. SettingsA 31-bed inpatient orthopedic/trauma unit in the southeastern United States. Participants/SubjectsSubjects of the pilot study were hospitalized adults over the age of 18 with pre-existing opioid tolerance or opioid use disorder who were experiencing acute pain. MethodsThis pilot study examined the effect of a 10-minute guided meditation activity through immersive virtual reality on the reported acute pain of hospitalized adults (n = 11) with pre-existing opioid tolerance or opioid use disorders. The Calm® application on an Oculus Go® virtual reality head-mounted display was used for the meditation activity. ResultsBefore the intervention, the mean patient-reported pain rating was 6.68, and the mean pain score after the virtual reality experience was 3.36. Using the Wilcoxon signed rank test, this was a statistically significant difference (p = .003). Patients were also observed and queried regarding any significant side effects or other incidental findings, none of which were reported. ConclusionsThis study demonstrates that the use of guided meditation through virtual reality can result in statistically significant reductions in patient-reported pain scores.

Reductions in sickness with repeated exposure to HMD-based virtual reality appear to be game-specific

While head-mounted display (HMD) based gaming is often limited by cybersickness, research suggests that repeated exposure to virtual reality (VR) can reduce the severity of these symptoms. This study was therefore aimed at: (1) examining the exposure conditions required to reduce cybersickness during HMD VR; and (2) learning whether such reductions generalise from one HMD VR game to another. Our participants played two commercially-available HMD VR video games over two consecutive days. Their first exposure to HMD VR on both days was always to a 15-min virtual rollercoaster ride. On Day 1, half of our participants also played a virtual climbing game for 15-min, while the rest of them finished testing early. Participants in the latter group were only exposed to the climbing game late on Day 2. We found that sickness was significantly reduced for our participants on their second exposure to the virtual rollercoaster. However, sickness to the rollercoaster on Day 2 was unaffected by whether they had played the climbing game on Day 1. Sickness during virtual climbing was also unaffected by group differences in exposure to the virtual rollercoaster. This convergent evidence suggested that the reductions in cybersickness produced by repeated exposure to HMD VR were game-specific. While these benefits did not generalise to the second game, two 15-min exposures to the same HMD VR game was sufficient to significantly reduce cybersickness in this study.

Novel Hybrid Brain-Computer Interface for Virtual Reality Applications Using Steady-State Visual-Evoked Potential-Based Brain-Computer Interface and Electrooculogram-Based Eye Tracking for Increased Information Transfer Rate.

Brain–computer interfaces (BCIs) based on electroencephalogram (EEG) have recently attracted increasing attention in virtual reality (VR) applications as a promising tool for controlling virtual objects or generating commands in a “hands-free” manner. Video-oculography (VOG) has been frequently used as a tool to improve BCI performance by identifying the gaze location on the screen, however, current VOG devices are generally too expensive to be embedded in practical low-cost VR head-mounted display (HMD) systems. In this study, we proposed a novel calibration-free hybrid BCI system combining steady-state visual-evoked potential (SSVEP)-based BCI and electrooculogram (EOG)-based eye tracking to increase the information transfer rate (ITR) of a nine-target SSVEP-based BCI in VR environment. Experiments were repeated on three different frequency configurations of pattern-reversal checkerboard stimuli arranged in a 3 × 3 matrix. When a user was staring at one of the nine visual stimuli, the column containing the target stimulus was first identified based on the user’s horizontal eye movement direction (left, middle, or right) classified using horizontal EOG recorded from a pair of electrodes that can be readily incorporated with any existing VR-HMD systems. Note that the EOG can be recorded using the same amplifier for recording SSVEP, unlike the VOG system. Then, the target visual stimulus was identified among the three visual stimuli vertically arranged in the selected column using the extension of multivariate synchronization index (EMSI) algorithm, one of the widely used SSVEP detection algorithms. In our experiments with 20 participants wearing a commercial VR-HMD system, it was shown that both the accuracy and ITR of the proposed hybrid BCI were significantly increased compared to those of the traditional SSVEP-based BCI in VR environment.

Optical design and pupil swim analysis of a compact, large EPD and immersive VR head mounted display

Virtual reality head-mounted displays (VR-HMDs) are crucial to Metaverse which appears to be one of the most popular terms to have been adopted over the internet recently. It provides basic infrastructure and entrance to cater for the next evolution of social interaction, and it has already been widely used in many fields. The VR-HMDs with traditional aspherical or Fresnel optics are not suitable for long-term usage because of the image quality, system size, and weight. In this study, we designed and developed a large exit pupil diameter (EPD), compact, and lightweight VR-HMD with catadioptric optics. The mathematical formula for designing the catadioptric VR optics is derived. The reason why this kind of immersive VR optics could achieve a compact size and large EPD simultaneously is answered. Various catadioptric forms are systematically proposed and compared. The design can achieve a diagonal field of view (FOV) of 96° at -1 diopter, with an EPD of 10 mm at 11 mm eye relief (ERF). The overall length (OAL) of the system was less than 20 mm. A prototype of a compact catadioptric VR-HMD system was successfully developed.

Cybersickness and postural stability of first time VR users playing VR videogames

This study investigated symptoms of cybersickness and postural instability experienced by new users of head-mounted display virtual reality (HMD-VR), playing VR videogames over long and repeated sessions, and moderation of these symptoms by previous videogame experience and intensity of videogame stimulus.Cybersickness (SSQ) and postural stability (anterior-posterior path-velocity) of new users of VR (n = 80) was collected PRE-VR, POST-VR and 10 min after completing (POST-RECOVERY) a VR gaming experience. Users comprised of videogamers (n = 40) and non-videogamers (n = 40), who were randomly assigned to play either action (high-intensity stimuli) or adventure (low-intensity stimuli) games in VR for 30 min and repeated twice, one week apart.All participants, irrespective of gaming status and genre of game, experienced significant cybersickness after 30 min in VR using current-generation HMD-VR technology, and did not adapt (POST-VR) after two sessions. However videogamers were able to recover (POST-RECOVERY) from cybersickness induced in VR significantly better than non-videogamers.All participants experienced significantly better postural stability after 30 min in VR, irrespective of gaming experience or genre of game.Developers should create VR experiences that minimise negative symptoms of cybersickness and postural instability experience by new users of VR.

Impacts of Cues on Learning and Attention in Immersive 360-Degree Video: An Eye-Tracking Study.

Immersive 360-degree video has become a new learning resource because of its immersive sensory experience. This study examined the effects of textual and visual cues on learning and attention in immersive 360-degree video by using eye-tracking equipment integrated in a virtual reality head-mounted display. Participants (n = 110) were randomly assigned to one of four conditions: (1) no cues, (2) textual cues in the initial field of view (FOV), (3) textual cues outside the initial FOV, and (4) textual cues outside the initial FOV + visual cues. The results showed that the cues (annotations or annotations + arrows) helped learners achieve better learning outcomes and spend more time focusing on the areas with cues. In addition, the study found a serious imbalance in the distribution of learners’ attention in each region of the video. The attention directed to textual cues in the initial FOV is much higher than the attention directed to textual cues outside the initial FOV. Adding visual cues can effectively direct attention to textual cues outside the initial FOV and alleviate the imbalance of attention distribution. Consequently, adding cues to immersive 360-degree video can be an appropriate approach to promote learning and guide attention in immersive 360-degree video learning environments. This study provided new insights into the design and development of immersive 360-degree video instructional resources.

VR Users Are More Relaxed and Optimistic during COVID Lockdown than Others

Numerous studies have shown how the confinement period linked to the health situation of COVID-19 (SARS-CoV2) has been psychologically destructive for many people. These psychological disorders are generally linked to confinement and isolation. At the same time, virtual reality tools are becoming more popular, the level of immersion in cheap HMD (Head Mounted Display) helmets today allows access to a satisfactory level of presence. Our theory, widely supported by substantial literature, is that the regular use of immersive Virtual Reality during periods of confinement could allow users to better endure the psychological constraints. We observed the correlation between the weekly use of HMD Virtual Reality headsets, during the COVID-19 confinement period and the levels of well-being of users. Our study involved n = 56 participants divided into two groups of users and non-users of HMD headset. They answered 2 SWEMWBS and ONS questionnaires plus a social trust question. The results show a significant correlation between the use of virtual reality headset during COVID-19 lockdown and the level of relaxation and optimistic feeling but also a correlation between this use of VR (Virtual Reality) HMD and the feeling of being less close to others during the same period.

VR facial expression tracking via action unit intensity regression model

Virtual Reality (VR) Head-Mounted Displays (HMDs), also known as VR headsets, are powerful devices that provide interaction between people and the virtual 3D world generated by a computer. For an immersive VR experience, the realistic facial animation of the participant is crucial. However, facial expression tracking has been one of the major challenges of facial animation. Existing face tracking methods often rely on a statistical model of the entire face, which is not feasible as occlusions arising from HMDs are inevitable. In this paper, we provide an overview of the current state of VR facial expression tracking and discuss bottlenecks for VR expression re-targeting. We introduce a baseline method for expression tracking from single view, partially occluded facial infrared (IR) images, which are captured by the HP reverb G2 VR headset camera. The experiment shows good visual prediction results for mouth region expressions from a single person.

Immersive virtual reality (VR) training increases the self-efficacy of in-hospital healthcare providers and patient families regarding tracheostomy-related knowledge and care skills

Background:Virtual reality (VR)-based simulation in hospital settings facilitates the acquisition of skills without compromising patient safety. Despite regular text-based training, a baseline survey of randomly selected healthcare providers revealed deficiencies in their knowledge, confidence, comfort, and care skills regarding tracheostomy. This prospective pre–post study compared the effectiveness of regular text- and VR-based intervention modules in training healthcare providers’ self-efficacy in tracheostomy care skills.Methods:Between January 2018 and January 2020, 60 healthcare providers, including physicians, nurses, and respiratory therapists, were enrolled. For the intervention, a newly developed head-mounted display (HMD) and web VR materials were implemented in training and clinical services. Subsequently, in-hospital healthcare providers were trained using either text or head-mounted display virtual reality (HMD-VR) materials in the regular and intervention modules, respectively. For tracheostomy care skills, preceptors directly audited the performance of trainees and provided feedback.Results:At baseline, the degree of trainees’ agreement with the self-efficacy-related statements, including the aspects of familiarity, confidence, and anxiety about tracheostomy-related knowledge and care skills, were not different between the control and intervention groups. At follow-up stage, compared with the regular group, a higher percentage of intervention group’ trainees reported that they are “strongly agree” or “somewhat agree” that the HMD-VR simulation increases their self-efficacy, including the aspects of familiarity and confidence, and reduced their anxiety about tracheostomy-related knowledge and care skills. After implementation, a higher degree of trainees’ average satisfaction with VR-based training and VR materials was observed in the intervention group than in the regular group. Most reported that VR materials enabled accurate messaging and decreased anxiety. The increasing trend of the average written test and hands-on tracheostomy care skills scores among the intervention group trainees was significant compared to those in the regular group. The benefits of HMD-VR simulations and web-VR material-based clinical services for in-hospital healthcare providers and patient families persisted until 3 to 4 weeks later.Conclusion:The current study suggests that VR materials significantly enhance trainees’ self-efficacy (increased familiarity, increased confidence, and reduced anxiety) and their satisfaction with the training, while motivating them to use acquired knowledge and skills in clinical practice.

Spatially resolved transcriptomics in immersive environments

Spatially resolved transcriptomics is an emerging class of high-throughput technologies that enable biologists to systematically investigate the expression of genes along with spatial information. Upon data acquisition, one major hurdle is the subsequent interpretation and visualization of the datasets acquired. To address this challenge, VR-Cardiomicsis presented, which is a novel data visualization system with interactive functionalities designed to help biologists interpret spatially resolved transcriptomic datasets. By implementing the system in two separate immersive environments, fish tank virtual reality (FTVR) and head-mounted display virtual reality (HMD-VR), biologists can interact with the data in novel ways not previously possible, such as visually exploring the gene expression patterns of an organ, and comparing genes based on their 3D expression profiles. Further, a biologist-driven use-case is presented, in which immersive environments facilitate biologists to explore and compare the heart expression profiles of different genes.