The aim of the research is to evaluate the structural and biological parameters of the spawning stock of the turukhanskaya form of the Siberian vendace Coregonus sardinella (Valenciennes, 1848) from the Yenisei River and the state of the commercial stock of this fish species in the period from 2014 to 2021. Research methods: in the research used the ichthyological material collected in the period from 2014 to 2021 in the lower reaches of the Yenisei River (near the Dudinka town and the village of Levinsky Sands). Processing of ichthyological materials was carried out according to generally accepted methods. The number of spawning herds of Siberian vendace was calculated using a virtual population analysis in Galland’s modification. Instant natural mortality rates by age groups were calculated using the method of L. A. Zykov. Results: According to the control catches, the age of the spawning stock of the turukhanskaya form of Siberian vendace in the Yenisei River was 2+–9+ years. Fish aged 4+ years, which in different years constituted from 47 to 68 % of the spawning stock, dominated in the population. The average long-term age of the spawning population in the study period was 4.2 years. The ratio of females and males in the spawning herd was close to 1:1 on average. Individual absolute fecundity of fishes varied in the range from 1.9 to 12.5 thousand eggs, increasing with increasing age and size of females. The average population fecundity is 2.6–5.3 thousand eggs. The number and biomass of the spawning herd in different years varied from 11.0 to 30.5 thousand individuals and from 630 to 1738 tons, respectively. Practical significance: the obtained results about the dynamics and structure of the spawning stock of the semi-anadromous form of the Siberian vendace from Yenisei River for the period from 2014 to 2021 will be used for prognostic purposes in the preparation of materials substantiating the volumes of the recommended catch in the basin of the Yenisei River. Conclusion: Based on the results of the analysis of the age, size-weight and sex structure, it was shown that the state of stocks of the semi-anadromous turukhanskaya form of the Siberian vendace in the Yenisei River is currently in a satisfactory condition.