Statement of problemThe effect of various gingival colors on the color differences of laminate veneers is unclear and comparative evaluations should be documented. PurposeThe purpose of this in vitro study was to investigate the influence of different gingival colors on the color differences of laminate veneers. Material and methodsFive maxillary typodonts were used to obtain study models using 5 different gingival colors: light pink (LP), dark pink (DP), orange (Or), brown (Br), and violet (V). A total of 45 laminate veneers were milled using A1-shaded lithium disilicate ceramic and cemented on natural tooth-colored substrates. Color parameters were assessed using a spectroradiometer at 3 measurement areas (cervical third, mid-third, and incisal third) along the midline of laminate veneer with a focus measuring diameter of 1 mm. Color differences (∆E*ab and ∆E00) were calculated and compared with perceptibility (PT: ∆E*ab=1.22, ΔE00=0.81) and acceptability (AT: ∆E*ab=2.66, ΔE00=1.77) visual thresholds. Color variation data were statistically analyzed using 2-way ANOVA and Tukey HSD tests (α=.05). ResultsTwo-way ANOVA results of the ∆E*ab values revealed significant interaction between the gingival color and the measurement area (P=.002). The ∆E*ab and ΔE00 values of laminate veneers were significantly higher in the LP-V group that presented values above AT (P<.001). Measurement area significantly influenced ∆E values of laminate veneers (P<.001). Greater ∆E values were registered at the measurement area of the cervical third in the groups of LP-DP, LP-Br, LP-V, and Or-V. Regardless of the measurement area, ∆E00 values below AT were obtained for the gingival color groups of LP-Or, DP-Or, DP-Br, and DP-V. ConclusionsGingival color influenced the color differences of laminate veneers. When the gingival color was a darker gingival color, rather than light pink, the color difference increased, especially at the measurement area of the cervical third.