The article substantiates and carries out a scientific assessment of the effectiveness of development and the peculiarities of the formation of the agro-production sphere in the conditions of our time. The subject-object basis of the research is the activity of enterprises in the agro-production sphere of Ukraine and agricultural enterprises of the Kharkiv region, Ukraine and foreign countries. The economy of the state and its development at the time of management depends more than anything on the progress and efficiency of the business entities of the agro-industrial complex (APC). In this context, agricultural entrepreneurship plays a key role in preserving the integrity of village territories, developing their infrastructure, and shaping the material well-being of the population, which covers not only the rural but also the general economy. In addition, agricultural entrepreneurship plays an important role in macroeconomic indicators, which are actively included in the gross domestic product of Ukraine. It occupies a stable leading position among other branches of the country’s economy.