The high prevalence of chronic forms of gingivitis among young individuals is an urgent problem of modern dentistry, the solution of which requires new approaches and methods. Thus, this study aimed to investigate the clinical and functional state of the periodontium at the initial inflammatory processes in the tissues and its correction using physical methods of treatment. Clinical examination, index assessment, laser Doppler flowmetry, and video registration of vacuum test in a patient with chronic gingivitis revealed an increase in gingival capillary resistance and improvement of microcirculation in the periodontium at the end of vacuum therapy combined with exposure to laser radiation of red wavelength on periodontal tissues in the complex of standard treatment measures. The results of the functional methods of research after the end of physical influence on periodontal tissues are confirmed by the decrease of bleeding and increase of oral hygiene level according to the clinical instrumental examination and by the absence of patient complaints. Thus, the clinical case demonstrates the promising application of vacuum-laser therapy in the complex treatment of chronic gingivitis.