Psychoactive substance use among Secondary School Students has become an increasing public health problem in many countries. This study assessed the prevalence and patterns of psychoactive substance use among senior secondary school students of community secondary school, Umuna. This is a descriptive cross-sectional study in which a sample size of 231 students was selected using simple random sampling technique. The instrument for data collection was questionnaire and data collected were analyzed using descriptive and inferential statistics and presented using tables. The study revealed that alcohol and tobacco were the most commonly abused substance. It also revealed that more than half (51.1%) of the respondents use substance on a daily basis and smoking and sniffing were the most common patterns used. Factors influencing substance use included; peer group pressure and family background. There is a psychoactive substance. It was recommended that Government should ensure the enforcement of anti-psychoactive substance laws and health workers should be trained on how to identify addicts, prevent, and treat victims of drug abuse.
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