The use of veterinary drugs in food-producing animals may result in drug residues in foodstuffs such as meat, milk, eggs, or honey. High degree of antibiotics residues consumption from animal products to human might affect immunological reactions and can unfavourably influence digestive microbiota in susceptible people. Antimicrobials also known as antibiotics, anti-infectives, antibacterials or chemotherapeutics, include synthetic and natural compounds. The introduction of antibiotics to the veterinary field started soon after the use of antibiotics for the treatment of bacterial diseases in humans. Detection of drug residues from tissues and other animal products could be quite an expensive, time consuming and laborious venture. To determine the withdrawal period, regulatory authorities must employ a scientific process that includes establishing the Maximum Residue Limit for that medicine. The growing use of antimicrobials to prevent and treat diseases, increases the probability of residues of these substances in products obtained from animals. Resistant microorganism can get access to human, either through direct contact or indirectly via milk, meat, and or egg. The ongoing threat of antibiotic contamination is one of the biggest challenges to public health that is faced not only by the African people, but also by the human population worldwide. Globally, more than half of all medicines are prescribed, dispensed or sold improperly. The first step in residue prevention is to make individuals and organizations aware of the problem through education by means of scientific literature, computer databases, veterinary consultations and the efforts of national organizations.
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