Vertical GaN power switch technology is expected to be utilized in next-generation medium to high voltage power converters due to the low ON-resistance and high breakdown voltage enabled by the improved critical electric field and mobility compared to Si and SiC-based devices. As large area substrates have become available by hydride vapor phase epitaxy (HVPE) and ammonothermal growth, the properties of nitrides are no longer dominated by defects introduced by heteroepitaxial growth, allowing recent realization of several fundamental vertical power devices, including diodes with edge termination, trench MOSFETs, and CAVETs. However, additional materials challenges are coming to the forefront that need to be understood and surmounted in order to allow vertical GaN power devices to achieve their full potential, notably the realization of repeatable thick drift layers with low background doping. To enable this, a deeper understanding of substrate preparation and the effects of the substrate and growth initiation on the characteristics of the epitaxial layers is required for MOCVD growth of homoepitaxial films. We investigate these effects on epi morphology, uniformity, and impurity incorporation by growing simultaneously on wafers from different vendors. The goal of this work is to detect and identify defects in GaN substrates with a series of quick, non-destructive, inexpensive techniques with capabilities of mapping whole wafers. We have characterized multiple substrates from over eight suppliers and the homoepitaxy grown on those substrates. All the substrates had nominally similar as-received specifications (resistivity, thickness, off-cut angle, bow, surface finish). The substrates were evaluated with a variety of techniques including Raman spectroscopy, photoluminescence, white light interferometry, and Nomarski imaging, enabling to detection of different concentrations of grain boundaries, sample impurities, point defects, v-shaped pits, polishing defects, crystal stress damage, and non-uniform insulating and conducive regions. The substrates can be characterized in two different categories: those with uniform characteristics, including carrier concentration, and those without. Comparing these results to those from homoepitaxial growth on the same wafers, the effects are both subtle and overt. Macroscopic surface morphology, which has shown a direct correlation to leakage current, copies and exaggerates that of the underlying substrate. Photoluminescence of the homoepitaxial surface along with Raman spectroscopy show that non-uniformities in the substrate carrier concentration can continue into the epitaxy. Following optical characterization, vertical Schottky diodes were fabricated to quickly evaluate device performance. While most of the films showed the ability to withstand high electric fields, those with more uniform properties in the substrate also showed more uniform electrical properties. These results show that the bulk substrates enable the path to high voltage vertical devices, but also show the significant influence that substrates can play in device performance.