The international Argo Program was launched at the turn of the millennium. It has since collected over 2 million vertical profiles of temperature and salinity from the upper 2000 m of the global ocean. Gridded interpolation is a technology that gives full play to the advantages of these profiles because they are scattered. This study develops a global gridded Argo dataset, called GDCSM-Argo, by using an improved gradient-dependent correlation scale method. The dataset is theoretically verified, its error-related statistics are recorded, and it is compared with other datasets to establish its reliability. The results show that the maximum mean RMSEs are 0.8 °C for temperature and 0.1 for salinity, and more than 90% of the analysis results are reliable under the statistical probability of 95%. Not only can GDCSM-Argo adequately preserve large-scale signals in the ocean but also retain more mesoscale features than other gridded Argo datasets. Preliminary applications also verify that GDCSM-Argo can systematically describe the spatio-temporal features of multiple elements in the global ocean, and is a useful tool in many areas of research.