PurposeOur aim in this study was to examine lettuce production in vertical farming or in conventional greenhouse production in Northern European conditions from the perspective of climate change impact and environmental sustainability. Further, the goal was to identify practices and choices that could mitigate adverse effects and increase resource-use efficiency, allowing the development of more sustainable production systems.MethodsThis article provides new information of the environmental impacts of lettuce production in greenhouses and vertical farming in Finland, compared using the life cycle assessment (LCA) methodology. The impact categories used were climate change impact, cumulative energy demand, resource use of fossil energy sources, resource use of minerals and metals, land use, and water scarcity. The system boundaries covered the production chains from cradle to farmgate, including inputs in production, as well as direct emissions caused by fertiliser use and the onsite composting of organic waste. The environmental impacts of the two production systems with different energy scenarios were assessed: (1) a greenhouse either with average or renewable energy; and (2) vertical farming either with average or renewable energy and with or without waste heat recovery. The data for vertical farming were based on one Finnish production site and supplementary data for the construction materials. The greenhouse data were based on a previous LCA investigation of average Finnish lettuce production.ResultsThe climate change and all other impact categories were lowest for lettuce produced in vertical farming with renewable energy and waste heat recovery. The climate change impact was largest for lettuce produced in greenhouse with average energy use. For energy use and energy resource use, the impacts of vertical farming were lower than greenhouse production, but for mineral and metal use and water scarcity, the impact of vertical farming was higher for average energy use without heat recovery. Direct land and irrigation water use on the production sites in Finnish circumstances represented only a small share of total land-use and water-use impacts on both production methods.ConclusionPaying attention to the energy source and heat recovery, the environmental sustainability can be advanced in both vertical and greenhouse production systems.