Verbal Assessment Research Articles

Effect of Age-Related Hearing Loss on Neuropsychological Test Performance

Effect of Age-Related Hearing Loss on Neuropsychological Test Performance

The Neural Dynamics of Individual Differences in Episodic Autobiographical Memory.

The ability to mentally travel to specific events from one’s past, dubbed episodic autobiographical memory (E-AM), contributes to adaptive functioning. Nonetheless, the mechanisms underlying its typical interindividual variation remain poorly understood. To address this issue, we capitalize on existing evidence that successful performance on E-AM tasks draws on the ability to visualize past episodes and reinstate their unique spatiotemporal context. Hence, here, we test whether features of the brain’s functional architecture relevant to perceptual versus conceptual processes shape individual differences in both self-rated E-AM and laboratory-based episodic memory (EM) for random visual scene sequences (visual EM). We propose that superior subjective E-AM and visual EM are associated with greater similarity in static neural organization patterns, potentially indicating greater efficiency in switching, between rest and mental states relevant to encoding perceptual information. Complementarily, we postulate that impoverished subjective E-AM and visual EM are linked to dynamic brain organization patterns implying a predisposition towards semanticizing novel perceptual information. Analyses were conducted on resting state and task-based fMRI data from 329 participants (160 women) in the Human Connectome Project (HCP) who completed visual and verbal EM assessments, and an independent gender diverse sample (N = 59) who self-rated their E-AM. Interindividual differences in subjective E-AM were linked to the same neural mechanisms underlying visual, but not verbal, EM, in general agreement with the hypothesized static and dynamic brain organization patterns. Our results suggest that higher E-AM entails more efficient processing of temporally extended information sequences, whereas lower E-AM entails more efficient semantic or gist-based processing.

Embedding lies into truthful stories does not affect their quality

SummaryWhen given the opportunity, liars will embed their lies into otherwise truthful statements. In what way this embedding affects the quality of lies, however, remains largely unknown. This study investigated whether lies that are embedded into truthful stories are richer in detail and contain higher quality details compared to lies that are part of entirely fabricated statements. Participants (N = 111) were asked to provide a statement that was either entirely truthful, entirely fabricated, or had the fabricated element of interest embedded into an otherwise truthful story. Results indicated that lies embedded in a fabricated statement are not qualitatively different from lies embedded in an otherwise truthful statement. Supporting Bayes factors provided moderate to strong evidence for this conclusion. Accordingly, verbal credibility assessment tools based on the verbal content measured in this study may be robust against the embedding of lies.

Prolonged Sitting Causes Lower Back Pain For Nursing Students In Yogyakarta, Indonesia

Individuals who spend most of their time sitting for long periods are at risk of experiencing low back pain. Pain complaints are the most common injuries in the work environment, both as administrator and in academia. The purpose of this study was to determine the relationship between the lengths of sitting during lectures with complaints of low back pain. This research is a quantitative analytic cross-sectional design conducted on 62 nursing students. Sitting time and pain complaints were measured using a questionnaire, physical examination (laseque test) and descriptive scale verbal pain assessment instrument (VDS). Data analysis used Fisher exact test with α: 5%. The results showed that the number of respondents who experienced low back pain complaints was 44 (71.0%) with a sitting time of ≥5 hours is 51 (82.3%) with a value of p = 0.025. The conclusion of this research is the length of sitting during lectures is at risk of causing low back pain

Clinician perspectives on the assessment of short-term memory in aphasia

ABSTRACT Background: Verbal short-term memory (STM) and the related ability, working memory (WM), are widely understood to be integral components of language production and comprehension. However, assessment of these abilities in people with aphasia is hampered by a lack of valid, standardized measures that are clinically appropriate. Focusing primarily on verbal STM, we held a series of five focus groups with speech-language pathologists (SLPs) to understand better their current clinical practices and their beliefs and attitudes regarding assessment of verbal STM in aphasia. Aims: The purpose of this study was to explore the attitudes, beliefs and preferences of clinical SLPs to determine: (1) current practices related to verbal STM assessment; (2) the extent to which practices reflect current theories of aphasia and the role of verbal STM in language processing; and (3) practical considerations regarding aphasia assessment in clinical practice. Methods & Procedures: Five focus groups were conducted using a semi-structured interview protocol with a total of 44 SLPs. Grounded theory methodology was used to collect, code and analyse the data. Codes were reviewed to identify emerging themes. Themes were compared to explore meta-themes, connections and potential theoretical frameworks. Outcomes & Results: Five main themes were identified: (1) The theoretical understanding that clinical SLPs have regarding the role of verbal STM in aphasia is not always consistent with clinical practice; (2) Clinical SLPs highly value functionally relevant assessments; (3) The intense time constraints in clinical practice affect all aspects of assessment; (4) Clinical SLPs feel that there is a lack of appropriate tests for assessment of STM in aphasia; and (5) Clinical SLPs prefer tests that are comprehensive, easy to administer and psychometrically sound. Conclusions: Clinical SLPs report a lack of standardized measures to assess STM in individuals with aphasia. Researchers are met with several challenges in the development of these tests including effective communication with clinicians regarding the benefit of verbal STM assessments, especially as it relates to functional skills, and the creation of a test that is comprehensive yet simple, quick and easy to administer.

Effect of Cold Application on Pain and Bruising in Patients With Subcutaneous Injection of Low-Molecular-Weight Heparin: A Meta-Analysis.

To evaluate the effect of cold application on pain and bruising after the subcutaneous injection of low-molecular-weight heparin, 8 electronic databases were searched for randomized controlled trials and quasiexperimental studies from the inception of the databases to June 2019. Review Manager 5.3 software was used for the heterogeneity test and meta-analysis. A total of 8 studies including 694 participants were analyzed. The cold application group assessed with the Verbal Descriptor Scale pain assessment tool showed significant reductions in pain intensity immediately after injection. Compared to the control group, the cold application group showed a reduction in the occurrence of bruises at 12 hours, 24 hours, and 48 hours after injection. There was no significant difference in the area of bruising in the cold application group at 48 hours after injection, but the area of bruising at 72 hours after injection was significantly reduced. These results show that cold application can reduce the incidence of pain and bruising after subcutaneous injection of low-molecular-weight heparin and reduce the area of bruising 72 hours after injection. Additional studies with larger sample sizes are needed to confirm these findings.

Deconstructing Poststroke Delirium in a Prospective Cohort of Patients With Intracerebral Hemorrhage.

Poststroke delirium may be underdiagnosed due to the challenges of disentangling delirium symptoms from underlying neurologic deficits. We aimed to determine the prevalence of individual delirium features and the frequency with which they could not be assessed in patients with intracerebral hemorrhage. Prospective observational cohort study. Neurocritical Care and Stroke Units at a university hospital. Consecutive patients with intracerebral hemorrhage from February 2018 to May 2018. None. An attending neurointensivist performed 257 total daily assessments for delirium on 60 patients (mean age 68.0 [SD 18.4], 62% male, median intracerebral hemorrhage score 1.5 [interquartile range 1-2], delirium prevalence 57% [n = 34]). Each assessment included the Confusion Assessment Method for the ICU, Intensive Care Delirium Screening Checklist, a focused bedside cognitive examination, chart review, and nurse interview. We characterized individual symptom prevalence and established delirium diagnoses using Diagnostic and Statistical Manual of Mental Disorders, fifth edition criteria, then compared performance of the Confusion Assessment Method for the ICU and Intensive Care Delirium Screening Checklist against reference-standard expert diagnosis. Symptom fluctuation (61% of all assessments), psychomotor changes (46%), sleep-wake disturbances (46%), and impaired arousal (37%) had the highest prevalence and were never rated "unable to assess," while inattention (36%), disorientation (27%), and disorganized thinking (18%) were also common but were often rated 'unable to assess' (32%, 43%, and 44% of assessments, respectively), most frequently due to aphasia (32% of patients). Including nonverbal assessments of attention decreased the frequency of 'unable to assess' ratings to 11%. Since the Intensive Care Delirium Screening Checklist may be positive without the presence of symptoms that require verbal assessment, it was more accurate (sensitivity = 77%, specificity = 97%, area under the receiver operating characteristic curve, 0.87) than the Confusion Assessment Method for the ICU (sensitivity = 41%, specificity = 88%, area under the receiver operating characteristic curve, 0.64). Delirium is common after intracerebral hemorrhage, but severe neurologic deficits may confound its assessment and lead to underdiagnosis. The Intensive Care Delirium Screening Checklist's inclusion of nonverbal features may make it more accurate than the Confusion Assessment Method for the ICU in patients with neurologic deficits, but novel tools designed for such patients may be warranted.

Exploring the Appropriateness of Test Accommodations for Chinese University Students with Hearing Impairment

This research evaluates the appropriateness of test accommodations among Chinese university students with hearing impairment, using reliability estimates and exploratory factor analysis. Study 1 explores the appropriateness of test directions accommodation for one nonverbal assessment (Group Embedded Figures Test) and two verbal assessments with increasing linguistic complexity levels (the Conceptions of Learning Inventory III and the Thinking Styles Inventory-Revised II) among 213 participants. Study 2 examines the appropriateness of combining test directions accommodation with language accommodation for the two revised verbal assessment, among a second sample of 366 participants. Results show that test directions accommodation was appropriate for nonverbal assessment, while the combination of test directions accommodation and language accommodation was more suitable for less linguistically complex verbal assessment. The limitations and significance of the study and implications for future studies are discussed.

Decision-making skills as a mediator of the #Tamojunto school-based prevention program: Indirect effects for drug use and school violence of a cluster-randomized trial

BackgroundThe aim of the present study was to evaluate a formal mediation analysis effect of the #Tamojunto program on adolescents’ drug use and violent behavior in schools through decision-making skills using a potential outcomes approach. MethodsAn in-cluster randomized controlled trial was conducted in 2014–2015 with 6691 7th- and 8th-grade students in 72 public schools in 6 Brazilian cities to evaluate the effects of the European drug prevention program Unplugged, called #Tamojunto in Brazil. Baseline data were collected prior to program implementation, and follow-up data were collected 9 and 21 months later. Mediation analysis using a potential outcomes approach, in which counterfactuals are modeled if positivity is met, was used to evaluate the indirect effects of the program #Tamojunto on the third-wave of drug use (alcohol, tobacco, marijuana, inhalants, and binge drinking) and school violence (bullying or physical, verbal and sexual aggression) assessment through decision-making skills. ResultsWhen controlling for all covariates, the Total Natural Indirect Effect (TNIE) was significant only for past-year drug use (TNIE = 0.003, 95%CI = 0.001; 0.007). In the adjusted models, 37.5% of the effect of the intervention on drug use was mediated by decision-making skills. ConclusionsThe #Tamojunto program increased drug use through decreasing decision-making skills. The findings demonstrate that this program changes decision-making skills but in the opposite direction proposed by the theoretical model of the program, suggesting that modifications are needed to produce the intended effect of the program.

436P - Assessing the quality of life of Filipino cancer patients: A survey of Filipino oncologists

BackgroundWith the advent of personalized medicine, recent clinical trials have placed much emphasis on the OS and PFS of cancer patients. However, several international guidelines also emphasize the need for assessing the Health Related Quality of Life (HRQoL) as part of our holistic approach in the management of cancer patients. This study evaluated the present status of the Filipino oncologists’ approach in assessing the quality of life of cancer patients. MethodsThis was a cross-sectional study that utilized a survey questionnaire. Participants included physicians in the care of the cancer patient (consultants & trainees) – medical, surgical, radiation, gynecologic oncologists, and hematologists, who were contacted via email through the database of their respective societies, and personally during scientific meetings / conferences. Descriptive and multivariate analysis were used to analyze the data. Results312 oncologists participated. 96% reported that HQRoL assessment was important for clinical work, however 58% perceived HRQoL to be a vague term; 69% agreed that verbal HRQoL assessments were generally enough, and 39% reported that their patients did not accept HRQoL questionnaires. Furthermore, 78% did not know which HRQoL assessment tool to use, and that the questionnaires were too extensive and too lengthy for routine use; 55% reported that they did not feel sufficiently trained to assess HRQoL. About 89.42% reported that they will be more confident if local HRQoL assessment guidelines will be present, and 92.95% agreed to the use of a unified HRQoL assessment tool for Filipino cancer patients. ConclusionsFilipino oncologists perceived HRQoL patient assessments to be important in clinical practice. However, majority did not know which tool to use and did not feel sufficiently trained to assess HRQoL. The creation of a practice guideline that would facilitate the use of a unified HRQoL assessment tool (containing 5-15 questions) for Filipino cancer patients will be explored. Legal entity responsible for the studyThe Authors. FundingHas not received any funding. DisclosureAll authors have declared no conflicts of interest.

The association between caesarean section and cognitive ability in childhood.

Global rates of caesarean section (CS) rates have increased rapidly in recent years. This is a growing public health concern as it has been proposed that CS may impact cognitive outcomes in childhood. However, the evidence for this association is limited and inconsistent. Therefore, the aim of this study was to investigate the relationship between obstetric mode of delivery and longitudinal cognitive outcomes in childhood. We examined this question using data from a longitudinal cohort study of 8845 participants from the Millennium Cohort Study, a nationally representative UK cohort, who completed a range of verbal and visual-spatial cognitive assessments at ages 3, 5, 7 and 11years. We found a statistically significant association between planned CS and visual-spatial cognitive delay in the pattern construction assessment at age 5 (OR 1.31, 95% CI 0.99-1.72) and age 7 (OR 1.42, 95% CI 1.12-1.81). Additionally planned CS was also associated with increased odds of "early childhood delay" (OR 1.70, 95% CI 1.15-2.50) and borderline increased odds of "persistent delay" (OR 1.37, 95% CI 0.99-1.89) in visual-spatial cognitive tests. Mode of delivery was not associated with verbal ability or with patterns of delay at any age point in verbal cognitive tests. We have reported a small association between planned CS and visual-spatial cognitive delay in childhood. However, while this result should be interpreted with caution, it highlights the need to further explore this potential relationship and the causal basis of such an association.

Study on the Relationship between Worker States and Unsafe Behaviours in Coal Mine Accidents Based on a Bayesian Networks Model

Unsafe behaviours, such as violations of rules and procedures, are commonly identified as important causal factors in coal mine accidents. Meanwhile, a recurring conclusion of accident investigations is that worker states, such as mental fatigue, illness, physiological fatigue, etc., are important contributory factors to unsafe behaviour. In this article, we seek to provide a quantitative analysis on the relationship between the worker state and unsafe behaviours in coal mine accidents, based on a case study drawn from Chinese practice. Using Bayesian networks (BN), a graphical structure of the network was designed with the help of three experts from a coal mine safety bureau. In particular, we propose a verbal versus numerical fuzzy probability assessment method to elicit the conditional probability of the Bayesian network. The junction tree algorithm is further employed to accomplish this analysis. According to the BN established by expert knowledge, the results show that when the worker is in a poor state, the most vulnerable unsafe behaviour is violation, followed by decision-making error. Furthermore, insufficient experience may be the most significant contributory factor to unsafe behaviour, and poor fitness for duty may be the principal state that causes unsafe behaviours.

Impact of the Orientation of the Ordered Fuzzy Assessment on the Simple Additive Weighted Method

We examine some aspects of the use of Simple Additive Weighting method to evaluate decision alternatives. Decision alternative attributes may be evaluated by verbal assessments which by their nature are imprecise. This means that for the purposes of Simple Additive Weighting method, any verbal assessment is represented by a fuzzy number being an imprecise approximation of a number. In this paper, all verbal assessments are represented by ordered fuzzy numbers. This approach is justified in the way that any ordered fuzzy number is additionally equipped with orientation, i.e., information about the location of the approximated number. The family of all ordered fuzzy numbers is divided into centrally symmetric families of positively oriented fuzzy numbers and of negatively oriented fuzzy numbers. The main purpose of this paper is to examine the consequences of omitting orientation of criterion ratings. We restrict all considerations to the case of trapezoidal oriented fuzzy numbers. We prove the mathematical theorem that an orientation omission can result in an increase in risk when choosing the right decision alternative. We study an empirical example of the Simple Additive Weighting method application to rank some negotiation offers. From the discussion, it follows that an orientation omission results in an increase in risk.

Pre- and Post-therapy Assessment of Clinical Outcomes and White Matter Integrity in Autism Spectrum Disorder: Pilot Study.

Objective: This pilot study aims to identify white matter (WM) tract abnormalities in Autism Spectrum Disorders (ASD) toddlers and pre-schoolers by Diffusion Tensor Imaging (DTI), and to correlate imaging findings with clinical improvement after early interventional and Applied Behavior Analysis (ABA) therapies by Verbal Behavior Milestones Assessment and Placement Program (VB-MAPP).Methods: DTI scans were performed on 17 ASD toddlers/pre-schoolers and seven age-matched controls. Nine ASD patients had follow-up MRI 12 months following early intervention and ABA therapy. VB-MAPP was assessed and compared at diagnosis, 6 and 12 months after therapies. Tract-Based Spatial Statistics (TBSS) was used to measure fractional anisotropy (FA), mean diffusivity (MD), axial diffusivity (AD), and radial (RD) diffusivity.Results: VB-MAPP scores improved at 6 and 12 months after early intervention and ABA therapy compared to scores at baseline. TBSS analysis showed significant FA decrease and/or RD increase in ASD patients before therapy vs. controls in inferior fronto-occipital fasciculi, uncinate fasciculi, left superior fronto-occipital fasciculus, forceps minor, left superior fronto-occipital fasciculus, right superior longitudinal fasciculus, corona radiate bilaterally, and left external capsule. A significantly FA increase in 21 tracts and ROIs is reported in post- vs. pre-therapy DTI analysis.Conclusion: DTI findings highlighted ASD patient WM abnormalities at diagnosis and confirmed the benefits of 12 months of early intervention and ABA therapy on clinical and neuro imaging outcomes.

Needle Placement and Position of Electrical Stimulation Inside Sacral Foramen Determines Pelvic Floor Electromyographic Response—Implications for Sacral Neuromodulation

Lead placement within the sacral foramen in sacral neuromodulation patients is guided by visual assessment of the contraction of the pelvic floor musculature (PFM) and/or verbal assessment of the sensation and location of sensation upon stimulation. Generally, lead placement is proceeded by needle probing. This study evaluates which location inside a single sacral foramen would be most ideal for the release of the permanent electrode lead, by measuring electromyographic (EMG) motor responses of the PFM upon stimulation of a peripheral nerve evaluation (PNE) needle. In eight patients, four standard PNE needles, and in one patient, two PNE needles, were introduced into the same foramen, parallel to the midline and parallel to each other. Position was verified by X-ray. Needles were stimulated (square pulsed waves, 210 μsec, 14 Hz) at increasing amplitudes (1-2-3-5-7-10 mA). PFM EMG was measured using the Multiple Array Probe (MAPLe) placed intravaginally or intrarectally, with 24 derivations. For this study, the mean (normalized) EMG was taken of all electrodes and different positions within the foramen were compared using the Wilcoxon signed rank test. A total of 202 PFM EMG measurements were recorded upon stimulation. EMG motor responses of the PFM for current stimulation = <2 mA showed statistically significant higher mean (normalized) EMG values for needles positioned cranial, medial, and cranial-medial, in comparison to needles positioned caudal, lateral, and caudal-lateral (p = 0.004; p = 0.021; p = 0.002). Our data suggest stronger PFM contractions are elicit in cranial- and medial-placed PNE needles upon stimulation with clinically relevant current amplitudes (≤ 2 mA). Placement of the lead should aim for this spot in the foramen.

C-64 The Verbal Shift Social Assessment: Examining Differences in Emotion Recognition, Attention, and Event Prediction Between Children with HFASD, ADHD, and Typically Developing Peers

Abstract Objective A pilot study of an experimental instrument extending the ‘verbal shift’ hypothesis indicating HFASD bias towards language over nonverbal cues (Grossman, Klin, Carter &amp; Volkmar, 2000). We hypothesized HFASD differentiates from ADHD in social video interpretation in the degree of reliance on semantic content for correct responses. Method 68 children ages 7-13 were recruited from the community (21 HFASD, 20 ADHD, 27 Control). Children viewed video pairs of social interaction. A “masked” version preserved prosody and visual cues, but not words. An “unmasked” version was naturalistic, with interpretable spoken language. Three questions were asked following each video scene (masked presented first): 1) the emotion of an actor, 2) a question to verify child was attending, 3) prediction about what might happen next. MANCOVA with post-hoc analysis was used to examine the between-group differences on performance as measured by the number of correct responses gained when the videos were unmasked. Results There were no group differences in age, gender, and WASI PRI. With WASI VCI controlled, emotion recognition and prediction questions differed significantly between groups (F = 3.907, p = .025, pEta2 = .109; F = 4.725, p = .012, pEta2 = .129), with ASD having the largest unmasked&gt;masked correct gain compared to ADHD (p = .05; p = .029) and controls (p = .009; p = .004) There were no differences between ADHD and controls. The attention question did not differ among groups; focus on the details of the videos was similar in participants regardless of diagnosis. Conclusions Results of this pilot study indicate that emotion recognition and event prediction may be useful diagnostic predictors when differentiating HFASD from ADHD using naturalistic video stimuli.

Visual and verbal learning and memory in cystinosis

Cystinosis is a rare genetic lysosomal storage disorder characterized by the accumulation of cystine in lysosomes. Many organ systems are vulnerable to this cystine accumulation including the CNS. A past study demonstrated that children with cystinosis have deficits in visual learning and memory while their verbal learning and memory and global intellectual function are spared (Spilkin, Ballantyne, & Trauner, 2009). However, no related study has been performed to assess the dissociation between visual and verbal learning and memory in adults with cystinosis who have had the benefit of longterm treatment with the cystine-depleting agent, cysteamine. In this study we assessed visual and verbal learning and memory in 15 adults with cystinosis, with a mean age of 30.2 years. The results indicate that adults with cystinosis have no significant deficits in either verbal or visual learning and memory. However, the individuals did perform better on the verbal assessment. The results suggest that if early and continued treatment is given to individuals with cystinosis there is a relative sparing of visual learning and memory that might have otherwise declined. This emphasizes the essential nature of the proper clinical management of cystinosis.

An Exploratory Study on Mind Wandering, Metacognition, and Verbal Creativity in Chilean High School Students

The purpose of this study was to explore the relationship between mind wandering, metacognition, and creativity in a sample of Chilean high school students. Two hundred and twenty-eight secondary students took three self-report scales on mind wandering, metacognitive strategies and reading difficulties, two verbal creativity assessments, a test of fluid intelligence and a measure of attentional capacity. Correlational analysis, a single multiple hierarchical regression, and a three-way moderation model were performed on data. Controlling for fluid intelligence and reading difficulties, metacognition and attention predicted creativity while mind wandering did not. Additionally, a three-way interaction showed that mind wandering had a positive impact on creativity only among students with both high attention and high metacognition. These results reflect the relevance of cognitive self-regulation for creativity during the high school years. Educational implications are discussed.

The adaptation of the Burn Specific Health Scale-Revised (BSHS-R) into the Portuguese context

The objective of this study was the adaptation of the Burn Specific Health Scale-Revised (BSHS-R) into the Portuguese context. The authors of the original version of BSHS-R with 31 items are Blalock, Bunker and DeVellis and it was developed to evaluate the health status of burns victims.The Brazilian version of the BSHS-R was translated from Portuguese (Brazil) to Portuguese (Portugal), through a semantic adaptation process, by independent Portuguese-Brazilian specialists, followed by a verbal comprehension assessment of all items, with a heterogeneous group of people, in terms of age, education and occupation.After the survey adaptation to Portuguese (Portugal), a psychometric study of the BSHS-R has been realized with a sample of 92 patients, which had been hospitalized in the Burn, Plastic and Reconstructive Surgery units of the Prelada Hospital, Porto, Portugal. For the process of instrument validation, a factorial exploratory analysis has been conducted and the internal consistency indicators were analysed using Cronbach’s alpha (reliability).The results analysis allowed to assess and identify the validity of the construct through the factorial exploratory analysis, which confirmed the same previous factorial structure identified in the original language and in the Brazilian version. The BSHS-R also presented good internal consistency indicators (global α = .921; affect and body image α = .874; heat sensitivity α = .830; simple functional abilities α = .893; treatment regimens α = .772; work α = .876; interpersonal relationships α = .804).The Portuguese (Portugal) adapted version has revealed useful, valid and reliable for the quality of life assessment related to the health of people that suffered burn injuries.

High-Frequency Repetitive Transcranial Magnetic Stimulation Applied to the Parietal Cortex for Low-Functioning Children With Autism Spectrum Disorder: A Case Series

Background: Repetitive transcranial magnetic stimulation (rTMS) is a safe and efficacious technique to stimulate specific areas of cortical dysfunction in several neuropsychiatric diseases; however, it is not known whether high-frequency rTMS (HF-rTMS) over the left inferior parietal lobule, in low functioning children with autism spectrum disorder (ASD), improves core symptoms. Method: Eleven low-functioning children with ASD completed two separate HF-rTMS treatment courses, 6 weeks apart. Each treatment course involved five 5-s trains at 20 Hz, with 10-min inter-train intervals, on left inferior parietal lobule each consecutive weekday for a 3-week period (15 treatments per course). Subjects were assessed at five time points: immediately before and after the first HF-rTMS course, immediately before and after the second HF-rTMS course, and 6 weeks after the second rTMS treatment course. Treatment effectiveness was evaluated using the Verbal Behavior Assessment Scale (VerBAS) and Autism Treatment Evaluation Checklist (ATEC). The latter test consists of four subtest scales: Language, Sociability, Sensory, and Behavior. In addition, daily treatment logbooks completed by parents were considered as one of the outcome measures. Results: Participants showed a significant reduction in language- and social-related symptoms measured by ATEC from pretreatment to the 6-week follow-up after the second treatment course. Moreover, some possible improvements in imitation and cognition were reported by caregivers. Conclusions: Our findings suggest that HF-rTMS over the left parietal cortex might improve core deficits in low-functioning children with ASD.