Lateral ventricular cerebrospinal fluid, CSF, pressure was measured in 58 calves ranging in age from 18 through 160 days. Average live weight was estimated to be 46kg at 18 days of age, 158kg at 160 days, with 7-day increases amounting to 6.2%. CSF pressure increased each 7 days by 2.5mm of synthetic CSF and was represented by the following linear regression equation: Y2 = −1 + .364X, r = .44, in which Y2 = CSF pressure in millimeters of synthetic CSF and X = days of age. At 18 days of age, the pressure was estimated to be 6mm and at 160 days, 5mm. Because of the unequal distribution of calves across all ages, no data between 76 and 138 days and beyond 160 days, the relationships between CSF pressure and age were considered tentative. This is especially so in light of previous observations that with advancing age cisternal CSF pressure of anesthetized calves in lateral recumbency plateaued at ages greater than 101 days. Possible cause(s) of the increasing CSF pressure with increasing age was discussed.