Ventricular Fibrillation Cardiac Arrest Model Research Articles

Study on brain protection of mild hypothermia in cardiopulmonary resuscitation

Cardiac arrest (CA) is often followed by postischemic-anoxic encephalopathy. A ventricular fibrillation CA model in dogs was used in this study to understand the effect of oxygen free radical (OFR) and lactate (LA) in the postischemic-anoxic encephalopathy, and to explore the effect and mechanism of mild hypothermia (32-36°C) induced immediately with reperfusion after cardiac arrest (resuscitation).