Four regimens now are recommended by the Center for Disease Control (CDC), Atlanta, for treating uncomplicated gonorrhea. The new schedules represent the first major revisions in treatment recommendations since 1974. Paul J. Wiesner, MD, director of the CDC's Venereal Disease Control Division, says the principal changes involve the elevation of oral regimens to equal status with other therapeutic approaches. The CDC officials conferred with 12 physician therapy consultants before offering these drug regimens of choice for uncomplicated gonococcal infections in men and women: Aqueous penicillin G procaine—4.8 million units injected intramuscularly at two sites, with 1.0 g of probenecid by mouth; Tetracycline hydrochloride—0.5 g by mouth one hour before or two hours after meals (because food and some dairy products interfere with absorption), four times a day for five days to a total dose of 10.0 g; Ampicillin sodium—3.5 g, with 1 g probenecid by