Distributed drive electric vehicles (DDEVs) eliminate the complex drivetrain. The independently driven in-wheel motors also endow the vehicle with more ability for improving maneuverability. To this end, this paper proposes an integrated control framework of torque vectoring (TV) and active front-wheel steering system (AFS) to ensure the vehicle lateral motion stability performance. First, the polytope method with finite vertices is employed to deal with the system uncertainties and simplify the modeling structure, based on which a distributed model predictive control is adopted to construct a dynamic interactive model between agents. Then, through introducing the game theory, a distributed parallel control scheme is developed to obtain the cooperative strategy of agents. Such a design can also satisfy the modular and scalable requirement for integrated chassis control. To ensure the system asymptotic stability, the terminal input combined with the terminal cost function are treated as the constraints in the game paradigm and then transformed as the linear matrix inequalities. Furthermore, a robust H <inline-formula xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink"> <tex-math notation="LaTeX">$\infty $</tex-math> </inline-formula> compensation method is used to suppress the system disturbance. Finally, the hardware-in-the-loop (HIL) tests are conducted to assess the control performance. The results verify the proposed integrated control scheme is effective to enhance the vehicle handling stability.