Accurate localization is crucial for safe operation of intelligent vehicle (IV). In practice, global positioning system (GPS) signals sometimes may be contaminated or lost, resulting in inaccurate positions of IV. In this article, the distance of IV’s position between previous frame and current frame is derived from Lidar point cloud registration. A novel slide window variational Bayesian (VB) based localization method is proposed for IV with multiple dynamics by fusing GPS and Lidar. In the proposed method, the state of IV, the motion model identity of IV, the measurement loss identity, and the loss probability of measurement are jointly estimated by the VB technique. The effectiveness of the proposed localization method is validated by simulations and field experiments.