Summary Quantitative characterization of deep, tight, and heterogeneous reservoirs plays an important role in identifying hydrocarbon pathways for effective and optimal reservoir field development. In this case study, we used an azimuthal prestack seismic anisotropic inversion approach to estimate attributes of horizontal transverse isotropy (HTI) caused by a set of vertical fractures, oriented cracks, and stress. Anisotropic inversion facilitated the conversion of interface properties to the corresponding layer-based properties, which led to the quantitative interpretation of reservoir properties related to azimuthal variation in seismic amplitudes. To estimate the anisotropy magnitude and the direction of the isotropy axis in HTI media, elastic properties (P-impedance and Vp/Vs) obtained from prestack seismic inversion (using six azimuth × four angle stack) served as inputs. The isotropic low-frequency model (LFM) is used as the foundation of the inversion for all azimuths, and the anisotropy effects are later added by updating the model along the azimuths. The direction of the isotropy plane resulting from the anisotropic inversion is determined by using the maximum horizontal stress as a prior constraint, which eliminates any inherent uncertainty. The workflow used effectively characterized the orientation and density of fractures from the recently discovered oilfield reservoirs of the Paleocene (Lockhart) formation located in Pakistan’s north Potwar Basin. It also helped improve the prediction accuracy for fractures in the study area. According to the observations (fractures) from the exploratory drilled well (D1) in the tight carbonate (Lockhart) reservoir, a significant amount of anisotropy magnitude is observed. This provides the basis for hydrocarbon exploration, field development, and reliable drilling decisions.