AbstractThe current study numerically treats the magnetic field impacts on the natural convection flow and entropy generation in a square cavity filled with hybrid nanofluid and induced by two isothermally heated semicircles at the bottom and left walls of the cavity. The cavity is filled by hybrid nanofluid (titanium oxide/silver‐water) and oriented under different inclination angles with the applied magnetic field. The simulations in this study were executed via a home‐made code written in the FORTRAN programing language. The numerical methodology considered to solve the coupled equations of continuity, momentum, energy, and entropy generation equations with the associated boundary conditions is the finite volume method and the full multigrid acceleration. Various wake parameters are considered in this research study, namely, the inclination angle of the cavity (α), the magnetic field inclination (γ), the Hartmann number (Ha), the Rayleigh number (Ra), the volume fraction of the hybrid nanofluid (ϕ) and the internal semicircles radii ratio (β). The major findings issued from the impact of these parameters on the fluid flow and heat transfer characteristics reveal that heat transfer and entropy generation are a decreasing function of the Hartmann parameter. Moreover, the total entropy generation is intensified by 85.23% from Ra = 103 to Ra = 106 for Ha = 10, by 85.818% for Ha = 50 and 83.813% for Ha = 100. Besides, the flow magnitude is found decreasing with increasing the radii ratio β of the semicircles. It is also found that optimal heat transfer rates deducted from the variation of average Nusselt number versus Ra for different volume fractions of the hybrid nanoparticles are obtained for the extreme values of the pertinent parameters (β = 1, ϕ = 8%, Ra = 106). Hence, the present work offers a useful tool and a parametric study for the research community and engineers on the design and optimization of thermal management systems used in a variety of industrial applications, such as heat exchangers, nuclear reactors, and energy systems.