Variation In Position Research Articles

A Novel Computationally Efficient Approach to Identify Visually Interpretable Medical Conditions from 2D Skeletal Data

Timely identification and treatment of medical conditions could facilitate faster recovery and better health. Existing systems address this issue using custom-built sensors, which are invasive and difficult to generalize. A low-complexity scalable process is proposed to detect and identify medical conditions from 2D skeletal movements on video feed data. Minimal set of features relevant to distinguish medical conditions: AMF, PVF and GDF are derived from skeletal data on sampled frames across the entire action. The AMF (angular motion features) are derived to capture the angular motion of limbs during a specific action. The relative position of joints is represented by PVF (positional variation features). GDF (global displacement features) identifies the direction of overall skeletal movement. The discriminative capability of these features is illustrated by their variance across time for different actions. The classification of medical conditions is approached in two stages. In the first stage, a low-complexity binary LSTM classifier is trained to distinguish visual medical conditions from general human actions. As part of stage 2, a multi-class LSTM classifier is trained to identify the exact medical condition from a given set of visually interpretable medical conditions. The proposed features are extracted from the 2D skeletal data of NTU RGB + D and then used to train the binary and multi-class LSTM classifiers. The binary and multi-class classifiers observed average F1 scores of 77% and 73%, respectively, while the overall system produced an average F1 score of 69% and a weighted average F1 score of 80%. The multi-class classifier is found to utilize 10 to 100 times fewer parameters than existing 2D CNN-based models while producing similar levels of accuracy.

Subaperture Keystone Transform Matched Filtering Algorithm and Its Application for Air Moving Target Detection in an SBEWR System

Long-time coherent integration is an effective approach to improve detection performance for weak air moving targets (AMTs). The range position variation and azimuth Doppler variation will easily exceed range gate and Doppler resolution in a long observation time, resulting in severe performance degradation, especially for high maneuverability target. Besides, the high detection performance and low computational complexity ability are, most of times, the contradiction requirements by using the existing long-time coherent integration algorithms. To overcome above constraints, a novel subaperture Keystone transform matched filtering (SAKTMF) method is developed in this paper based on the conventional hybrid integration algorithm, which can realize coherent integration both within the subaperture and among subapertures, effectively improving the detection performance of a weak moving target. Furthermore, the proposed SAKTMF is applied for weak AMT detection in space-borne early warning radar (SBEWR), which considers serious extended clutter, range migration, and Doppler migration problems simultaneously. Simulation experiments processing results show that the proposed method can provide improved detection performance compared with the conventional hybrid integration methods.

Assessment of Dimensional Changes in Arch Width and Palatal Rugae Pattern in Pre and Post Orthodontic Treatment

Introduction The three-dimensional alterations in the dentition and the entire dento-facial complex must be taken into account during orthodontic diagnosis and treatment planning. Palatal rugae gives us the reference plane we need for a longitudinal cast analysis and the structural stability of an orthodontic treatment is correlated with how much the palate surface has been deformed.Objective To evaluate the changes in arch width and quantify the dimensions positional variations and area of the rugae in extraction and non-extraction orthodontic cases.Methodology The study included a sample of 52 sets of pre and post models of orthodontically treated patients. Using digital calipers inter canine and inter premolar distances were measured in pre and post orthodontic treatment models and palatal rugae were carefully highlighted using 0.3 mm lead pencil. The highlighted palatal rugae were traced using matte acetate tracing sheet and graph sheet overlapped and measurements were done.Results A significant difference was found in the inter canine p lt0.026 and inter premolar p lt0.021 measurements in extraction group.Conclusion Inter canine width increased in extraction group. The antero posterior dimension of palatal rugae showed significant increase in dimension and increase in the surface area of palatal rugae pattern in non-extraction group.nbsp

Acoustic radiation force of elastic spherical shell with eccentric droplet in plane wave acoustic field

Based on the application of acoustic waves in cell manipulation, a model consisting of an elastic spherical shell and eccentric droplet is established to simulate a eukaryotic cell and analyze the acoustic radiation force (ARF) on the cell. In this work, we derive an exact expression for the ARF on the liquid-filled spherical shell. The influence of eccentric distance, radius of the eccentric droplet and impedance of the medium inside the liquid-filled spherical shell on the ARF are analyzed numerically. The results show that the ARF is very sensitive to the position and size of the eccentric droplet. As the eccentricity of the eccentric droplet increases, the ARF becomes greater. In a low frequency region (<i>ka</i><3) the resonance peak point increases, and the position of the curve ventral point shifts to the high frequency region (<i>ka</i>>3) with the increase of the radius of the eccentric droplet. The effect of the position variation on the ARF is more significant than that of the radius change, and both of their effects will be superimposed on each other. The ARF, as a function of <i>ka,</i> is mainly affected by the variation of the nucleus characteristic impedance. The ARF amplitude around <i>ka</i> = 5 increases and the position of the ventral point tends to shift rightwards with the enlargement of the nucleus impedance. Therefore, the radiation response at a certain frequency or in a cell size range can be enhanced when the nucleus impedance increases. The results of this study provide theoretical basis for the cell sorting and targeted therapy.

Variation in canine Position’s in unilateral cleft lip and palate patients - A case Series

Cleft lip/palate is a common congenital anomaly that occurs during birth. Incomplete fusion of the maxillary prominence and median nasal processes results in a small niche or indentation on the lip and palate that extends all the way up to the nose. The orofacial cleft can appear as isolated cleft lip, cleft lip with cleft palate, be associated with syndromes, or present unilaterally or bilaterally. Various management modalities are recommended depending on the extent and severity of the anomalies. Cleft lip and palate are frequently associated with developmental problems in the primary and permanent dentitions. To restore all of the aesthetic, functional, periodontal, and restorative components, it is critical to address the associated dental anomalies

Dosimetric Evaluation of Synthetic Computed Tomography Technique on Position Variation of Air Cavity in Magnetic Resonance-Guided Radiotherapy

Dosimetric Evaluation of Synthetic Computed Tomography Technique on Position Variation of Air Cavity in Magnetic Resonance-Guided Radiotherapy

Repeatability of Inertial Measurement Units for Measuring Pelvic Mobility in Patients Undergoing Total Hip Arthroplasty.

Consideration of pelvic mobility when positioning implants for total hip arthroplasty (THA) has been shown to reduce the risk of complications such as dislocation, squeaking and excessive wear. We aim to test the repeatability of pelvic tilt measurements taken between three positions (standing, flexed-seated and step-up) by an inertial measurement unit (IMU) and hence, evaluate their reliability in screening for high pelvic mobility in patients undergoing THA. The repeated IMU measurements of pelvic tilt were analysed for consistency and compared with measures taken by x-ray analysis. Our study showed greater variation in measures taken by the IMU particularly in the flexed-seated position. The patient's pelvic tilt in this position negatively correlated with their mid-back angle, suggesting the posture of the patient is a source of variation in the flexed-seated position if not kept consistent during assessments. IMUs were overall able to produce accurate and reliable measurements of pelvic tilt; however, protocols will need to be adjusted to factor in a patient's mid-back angle when taking future readings.

Fluxes of dissolved organic matter and nitrate and their contribution to soil acidification across changing permafrost landscapes in northwestern Canada

Climate warming is predicted to change the fluxes of dissolved organic matter and nitrate by increasing active layer thickness, plant productivity, and organic matter decomposition. These changes are hypothesized to increase mineral weathering and soil acidification rates. We investigated whether acidification rates and solute leaching fluxes are variable between permafrost-affected soils with different active layer thicknesses. We compared the fluxes of dissolved organic carbon (DOC) and total dissolved N and the ion fluxes associated with solute leaching and plant uptake to calculate proton budgets in the soils that differed in slope positions (upper slope and lower slope) and soil texture (clayey and sandy soils) in NW Canada. We found the wide variation in DOC and nitrate-N fluxes, depending on slope positions and soil texture. The nitrate-N fluxes were higher at the lower slope position of the sandy soil, compared to the upper slope position. Compared to sandy soils, the DOC fluxes from the organic horizons were higher in the clayey soils on shallower permafrost table. Organic acids were major proton sources in the organic horizons at all sites, but acidity was also contributed by nitrate (sandy and clayey soils at lower slope position) and carbonic acid (clayey soil at upper slope position). The weathering by carbonic acid lead to accumulation of short-range-order minerals in the clayey soils, while incipient podzolization of the sandy soils included the weathering of illite to vermiculite and the dissolution of short-range-order minerals. The shallower active layer thickness at the lower slope position resulted in lower plant productivity and acidification rates. In the permafrost-affected soils, the active layer thickness, the DOC and nitrate-N fluxes, and their contribution to acidification are dependent on the local variation in slope position and soil texture, as well as climate change.

Positional and dimensional relation of tendons around the first metatarsal bone with hallux valgus

It was aimed to reveal whether the positions and dimensions of the extrinsic and intrinsic muscle tendons related to the hallux around the first metatarsal bone are affected by the severity of hallux valgus (HV) and whether tendon positional changes and tendon sizes affect each other. In formalin-fixed 46 feet, three HV angle subgroups (normal, mild, and moderate/severe) were defined. Width, thickness, and cross-sectional area (CSA) of tendons of the extensor hallucis longus (EHL) and brevis (EHB), abductor hallucis (AH), and flexor hallucis longus (FHL) were measured. On the clock model created in coronal plane, positional variations of each tendon were determined. In the moderate/severe HV group, thickness and CSA of the EHB, width and CSA of the AH were smaller, compared to mild HV. Width and CSA of the FHL were smaller in moderate/severe HV than in the normal. Regardless of HV, the width and CSA of the FHL were greater in cases where the FHL was located more lateral, and the width of both FHL and AT were greater in cases where AH located was more plantar. The smaller tendon size of two intrinsic (one plantar and one dorsal) and one extrinsic muscle in the moderate/severe HV group indicates that changes in the tendons are evident in cases of high severity of HV but not in cases of mild HV. Accordingly, the changes do not appear to be due to a factor limited to only one aspect of the foot. It is recommended to consider the possible biomechanical effects of AH, FHL, and EHB tendon dimensional weakness in surgical planning in moderate/severe HV cases.

Effect of an Adjustable Hinged Carbon Fiber Operating Table on Sagittal Alignment of the Lumbar Spine

This is a prospective study that has been done to assess the lumbar sagittal alignment of patients positioned prone over an adjustable hinged carbon fiber operating table. The following three variations of table position have been considered: neutral, 20° convex, and 20° concave bending. A total of 33 patients who underwent lumbar disc herniation and lumbar canal stenosis surgery were enrolled. Patients who presented with spinal deformity akin to lumbar scoliosis or spondylolisthesis were excluded. For the surgical procedure, following the induction of endotracheal general anesthesia, patients were positioned prone on the adjustable hinged carbon fiber operating table. Radiographs of the lateral view of the lumbar spine were acquired for the three table positions, i.e., neutral, 20° convex, and 20° concave. The lumbar lordosis was measured on radiographs. The lumbar lordosis presented divergently in all three variations of the table (p < 0.01): 45.2 ± 11.0° in neutral; 52.0 ± 10.7° in 20° lumbar extension bending; and 35.9 ± 10.8° in 20° lumbar flexion bending. The efficacy of table bending was 46.5% in convex and 34.0% in concave bending. In conclusion, the lumbar lordosis in three different table positions were 35.9° in 20° convex bending, 45.2° in neutral, and 52.0° in concave bending. The efficacy of table bending was 46.5% in convex and 34.0% in concave bending.

Patterns of dietary niche breadth and overlap are maintained for two closely related carnivores across broad geographic scales

Ecological studies investigating niche breadth and overlap often have limited spatial and temporal scale, preventing generalizations across varying environments and communities. For example, it is not clear whether species having restricted diets maintain such patterns relative to closely related species and across their geographic range of co-occurrence. We used stable isotope analysis of hair and fur samples collected from four regions of sympatry for Canada lynx (Lynx canadensis) and bobcat (Lynx rufus) spanning southern Canada and the northern United States, to test the prediction that the more generalist species (bobcat) exhibits a wider dietary niche than the more specialist species (Canada lynx) and that this pattern is consistent across different regions. We further predicted that Canada lynx diet would consistently exhibit greater overlap with that of bobcat compared to overlap of bobcat diet with Canada lynx. We found that Canada lynx had a narrower dietary niche than bobcat, with a high probability of overlap (85–95%) with bobcat, whereas the bobcat dietary niche had up to a 50% probability of overlap with Canada lynx. These patterns of dietary niche breadth and overlap were consistent across geographic regions despite some regional variation in diet breadth and position, for both species. Such consistent patterns could reflect a lack of plasticity in species dietary niches. Given the increasingly recognized importance of understanding dietary niche breadth and overlap across large spatial scales, further research is needed to investigate the mechanisms by which broad-scale patterns are maintained across species and systems.

Effects of reconstruction methods on dose distribution for lung stereotactic body radiotherapy treatment plans.

The aim of the present study was to investigate the effect of tumour motion on various imaging strategies as well as on treatment plan accuracy for lung stereotactic body radiotherapy treatment (SBRT) cases. The ExacTrac gating phantom and paraffin were used to investigate respiratory motion and represent a lung tumour, respectively. Four-dimensional computed tomography (4DCT) imaging was performed, while the phantom was moving sinusoidally with 4s cycling time with three different amplitudes of 8, 16, and 24mm. Reconstructions were done with maximum (MIP) and average intensity projection (AIP) methods. Comparisons of target density and volume were performed using two reconstruction techniques and references values. Volumetric modulated arc therapy (VMAT) and intensity modulated radiation therapy (IMRT) were planned based on reconstructed computed tomography (CT) sets, and it was examined how density variations affect the dose-volume histogram (DVH) parameters. 4D cone beam computed tomography (CBCT) was performed with the Elekta Versa HD linac imaging system before irradiation and compared with 3D CBCT. Thus, various combinations of 4DCT reconstruction methods and treatment alignment methods have been investigated. Point measurements as well as 2 and 3D dose measurements were done by optically stimulated luminescence (OSL), gafchromic films, and electronic portal imaging devices (EPIDs), respectively. The mean volume reduction was 7.8% for the AIP and 2.6% for the MIP method. The obtained Hounsfield Unit (HU) values were lower for AIP and higher for MIP when compared with the reference volume density. In DVH analysis, there were no statistical differences for D95%, D98%, and Dmean (p > 0.05). However, D2% was significantly affected by HU changes (p < 0.01). A positional variation was obtained up to 2mm in moving direction when 4D CBCT was applied after 3D CBCT. Dosimetric measurements showed that the main part of the observed dose deviation was due to movement. In lung SBRT treatment plans, D2% doses differ significantly according to the reconstruction method. Additionally, it has been observed that setups based on 3D imaging can cause a positional error of up to 2mm compared to setups based on 4D imaging. It is concluded that MIP has advantages over AIP in defining internal target volume (ITV) in lung SBRT applications. In addition, 4D CBCT and 3D EPID dosimetry are recommended for lung SBRT treatments.

REFINED PHYSICAL PROPERTIES OF THE HD327083 BINARY SYSTEM

HD327083 is a member of a small group of supergiants exhibiting the B[e] phenomenon. It was found to be a binary system with an early-B and an early-F supergiant components. However the fundamental and orbital parameters of the system were not accurately known. We determined a new set of the system parameters that include the orbital period and the components’ masses using a combination of photometric and spectroscopic data. A new orbital period of 107.7 days was found from both the spectral line positional variations and the visual light curve. Absorption lines of the cool component show a radial velocity semi-amplitude of 48.3 kms −1 , similar to that of emission lines that originate around the hot component. The system shows partial eclipses. We estimated the components’ masses to be nearly equal and close to 6-8 M ? . The masses turned out to be smaller then the evolutionary masses that may be a consequence of a recent mass-transfer.

Quantifying the Sensitivity and Unclonability of Optical Physical Unclonable Functions

Due to their unmatched entropy, complexity, and security level, optical physical unclonable functions (PUFs) currently receive a lot of interest in the literature. Despite the large body of existing works, herein, one of their core features in detail is studied, namely, their physical unclonability. This article tackles this fundamental and yet largely unaddressed issue. In simulations and/or experiments, the sensitivity of diffraction‐based optical responses is investigated with respect to various small alterations such as variation in position, size, and number of the scatterers, as well as perturbations in the spatial alignment between the PUF and the measurement apparatus. The analysis focuses on 2D optical PUFs because of their relevance in integrated applications and the need to reply to security concerns that can be raised when the physical structure of the geometry is accessible. Among the results of this study, the sensitivity analysis shows that a positional perturbation of scatterers on the order of 30 nm, that is, far below the wavelength of the probing laser light of 632 nm wavelength, is sufficient to invalidate the PUF response and thus detect forgery attempt. These results support and quantify the high adversarial efforts required to clone optical PUFs, even for 2D layouts.

The Effect of Femur Positioning on Measurement of Tibial Plateau Angle: An In Vitro Study

Five canine cadaveric pelvic limbs with intact cranial cruciate ligaments were used to quantify the effect of variation in limb positioning on the radiographic measurement of the tibial plateau angle (TPA) with reference to the degree of femoral condyle superimposition. Intra-osseous pin placement and a custom jig design allowed the controlled three-dimensional manipulation of limbs. Medio-lateral digital radiographic projections were taken with perfect femoral hemicondylar superimposition to establish a "reference" TPA (difference in position = 0 mm), and subsequently in varying degrees of supination/pronation and abduction/adduction. The lack of femoral hemicondylar superimposition for each radiograph was quantified using a tangential line technique with reference to the long tibial axis. A total of 176 radiographs were each assessed by three observers. "True" TPA was measured and it ranged within 17-25° across all limbs assessed. Variation in femoral condylar positioning ranged from -13 mm to +13 mm proximo-distally, and -11 mm to +11 mm cranio-caudally. Moreover, 3 mm non-superimposition of the femoral condyles produced 90.6% of measurements with 1° difference between measured and "true" TPA, and a sensitivity of 97.9% for a 2° difference. Further reduction in femoral condylar superimposition to 4 mm reduced the frequency of 1° difference between measured and "true" TPA to 84.9%, and to 94.8% for a 2° difference. In conclusion, measurement of TPA in large breed dogs from radiographs with greater than 3 mm variation in femoral condylar superimposition should be interpreted with caution.

Transitioning from the Posterior Approach to the Direct Anterior Approach for Total Hip Arthroplasty.

Total hip arthroplasty (THA) using the direct anterior approach (DAA) is known to have a learning curve. The purpose of this study was to review cases where surgery was performed by an arthroplasty surgeon transitioning from the posterior approach (PA) to the DAA. We hypothesized similar complication rates and improvements in surgical duration over time. A review of 2,452 consecutive primary THAs was conducted. Surgical duration, length of stay (LOS), surgical complications, decrease in postoperative day (POD) 1 hemoglobin, transfusion rates, POD 0 and POD 1 pain scores, incision length, leg length discrepancy (LLD), and radiographic cup position were recorded. No differences in surgical duration were observed after the first 50 DAA cases. A shorter LOS was observed for the DAA, and statistical difference was appreciated after the first 100 DAA cases. There were no differences in periprosthetic fractures. A higher rate of infections and hip dislocations were observed with the PA. The PA showed an association with higher transfusion rates without significant difference in POD 1 decrease in hemoglobin over the first 100 DAA cases. Similar POD 0 and POD 1 pain scores with a smaller incision were observed for the first 100 DAA cases. The DAA cohort showed less variation in cup inclination, version, and LLD. DAA is safe and non-inferior in terms of reduced LOS, smaller incision, and less variation in cup position. Fifty DAA cases was noted to be the learning curve required before no differences in duration between approaches were observed.

Spatial variation in carbon source use and trophic position of ringed seals across a latitudinal gradient of sea ice

Anthropogenic climate change is causing changes to the Arctic sea-ice system with implications for the magnitude and timing of Arctic pelagic and ice-associated (sympagic) primary production that influences food web interactions. Ringed seals (Pusa hispida) are generalist predators that, as a species experience vastly different icescapes from low to high-Arctic latitudes. Quantifying spatial variation in their diet can help us understand how changes in sea-ice dynamics affect trophic interactions in Arctic marine food webs. However, multiple complementary analytical tools to examine variation in carbon source use and trophic dynamics in the diet of ringed seals have not yet been applied across their latitudinal range in the Arctic. We conducted stable isotope analysis (δ13C and δ15N) and measured highly branched isoprenoid diatom lipid biomarkers of ringed seals from the low, intermediate, and high Arctic (from 61.1°N to 77.5°N) to investigate spatial variation in their carbon source use and trophic position in relation to sea-ice dynamics. Both δ13C and highly branched isoprenoids indicated that ringed seals from higher latitudes had more sympagic carbon in their diet (liver δ13C: −18.3 ± 0.2 ‰, HBI: 89.9 ± 2.08 %) than ringed seals at lower latitudes (liver δ13C: −21.1 ± 0.1 ‰, HBI: 22.0 ± 2.73 %). Ringed seal trophic position increased from the low (3.78 ± 0.02) to high (4.76 ± 0.03) Arctic, suggesting increased fish consumption or a different trophic structure coinciding with the latitudinal change in carbon source. Ringed seals demonstrated a clear shift from low to high Arctic in the relative contribution of phytoplanktonic vs sympagic primary production. These patterns are likely linked to the vastly different icescapes in these environments and demonstrate that shifts in primary producer composition and Arctic food webs can be identified in ringed seal diets. Information on these prey and energy shifts over large spatial scales also provides insights into potential future changes to Arctic ecosystem function with continued sea-ice decline.

Timing of pegmatite emplacement and skarn formation in the Malyovitsa Unit, NW Rila: evidence from zonal grossular crystals

Contact Ca-skarns are formed in the marbles of the Malyovitsa Lithotectonic Unit as a result of emplacement of crosscutting pegmatite injections in the area of the Dzhendemski Ezera, NW Rila Mt. Large (up to 4 cm), well-shaped garnet crystals dominate the mineral association with additional vesuvianite, diopside, scapolite and zoisite. Garnets were selected for mineralogical, geochemical and U-Pb geochronological study. Their crystals show clear zonal pattern due to variation in the octahedral position (Fe3+/Al3+), although the overall composition defines grossular predominance (72–95 mol.% grossular; 4–24% andradite). Trace-element signatures reveal constant isomorphic incorporation of P, V, Zn, Ga, Ge and Y, REE, HFSE, U. Results from the in-situ U-Pb dating of the studied skarn materials suggest the timing of pegmatite intrusion onto the metamorphic rocks and marble-hosted skarn formation at 58.37±0.70 Ma.

First Light Preparations of the 4m ILMT

The 4[Formula: see text]m International Liquid Mirror Telescope (ILMT) is a zenith-pointing optical observing facility at ARIES Devasthal observatory (Uttarakhand, India). The first light preparatory activities of the ILMT were accomplished in April 2022 followed by on-sky tests that were carried out at the beginning of May 2022. This telescope will perform a multi-band optical (SDSS [Formula: see text], [Formula: see text] and [Formula: see text]) imaging of a narrow strip ([Formula: see text]) of sky utilizing the time-delayed integration technique. Single-scan ILMT images have an integration time of 102[Formula: see text]s and consecutive-night images can be co-added to further improve the signal-to-noise ratio. An image subtraction technique will also be applied to the nightly recorded observations in order to detect transients, objects exhibiting variations in flux or position. Presently, the facility is in the commissioning phase and regular operation will commence in March 2023. This paper presents a discussion of the main preparation activities before first light, along with preliminary results obtained.

Trial of Training to Reduce Driver Inattention in Teens with ADHD

BackgroundTeens with attention deficit–hyperactivity disorder (ADHD) are at increased risk for motor vehicle collisions. A computerized skills-training program to reduce long glances away from the roadway, a contributor to collision risk, may ameliorate driving risks among teens with ADHD.MethodsWe evaluated a computerized skills-training program designed to reduce long glances (lasting ≥2 seconds) away from the roadway in drivers 16 to 19 years of age with ADHD. Participants were randomly assigned in a 1:1 ratio to undergo either enhanced Focused Concentration and Attention Learning, a program that targets reduction in the number of long glances (intervention) or enhanced conventional driver’s education (control). The primary outcomes were the number of long glances away from the roadway and the standard deviation of lane position, a measure of lateral movements away from the center of the lane, during two 15-minute simulated drives at baseline and at 1 month and 6 months after training. Secondary outcomes were the rates of long glances and collisions or near-collisions involving abrupt changes in vehicle momentum (g-force event), as assessed with in-vehicle recordings over the 1-year period after training.ResultsDuring simulated driving after training, participants in the intervention group had a mean of 16.5 long glances per drive at 1 month and 15.7 long glances per drive at 6 months, as compared with 28.0 and 27.0 long glances, respectively, in the control group (incidence rate ratio at 1 month, 0.64; 95% confidence interval [CI], 0.52 to 0.76; P<0.001; incidence rate ratio at 6 months, 0.64; 95% CI, 0.52 to 0.76; P<0.001). The standard deviation of lane position (in feet) was 0.98 SD at 1 month and 0.98 SD at 6 months in the intervention group, as compared with 1.20 SD and 1.20 SD, respectively, in the control group (difference at 1 month, −0.21 SD; 95% CI, −0.29 to −0.13; difference at 6 months, −0.22 SD; 95% CI, −0.31 to −0.13; P<0.001 for interaction for both comparisons). During real-world driving over the year after training, the rate of long glances per g-force event was 18.3% in the intervention group and 23.9% in the control group (relative risk, 0.76; 95% CI, 0.61 to 0.92); the rate of collision or near-collision per g-force event was 3.4% and 5.6%, respectively (relative risk, 0.60, 95% CI, 0.41 to 0.89).ConclusionsIn teens with ADHD, a specially designed computerized simulated-driving program with feedback to reduce long glances away from the roadway reduced the frequency of long glances and lessened variation in lane position as compared with a control program. During real-world driving in the year after training, the rate of collisions and near-collisions was lower in the intervention group. (Funded by the National Institutes of Health; ClinicalTrials.gov number, NCT02848092.)