Variation Of Index Research Articles

Computational Modeling of Light Scattering in Polymer Nanoparticles for Optical Characterization

The scattering of light by polymeric nanoparticles is a crucial phenomenon in various applications, ranging from nanomedicine to nanophononics. This study introduces a theoretical framework for differentiating between absorption and scattering spectra in light interactions with these nanoparticles. Characteristic spectral data of nanoparticles synthesized via the reprecipitationmethod and suspended in an aqueous medium analyzed under electromagnetic radiation. These nanoparticles exhibit two primary optical phenomena: absorption and scattering. To fully understand their optical response, it is essential to separate these phenomena. This study established a relationship between wavelength variation, nanoparticle size, and radiation loss due to scatteringin an aqueous medium. Additionally, we calculated extinction efficiency and extinction factors as functions of wavelength, taking into account variations in nanoparticle radii and refractive indices.

Variations in Water Quality Index and Physicochemical Properties of Surface Water and Bottom Sediments of Selected Coastal Beaches of Niger Delta, Southern Nigeria

Variations in Water Quality Index and Physicochemical Properties of Surface Water and Bottom Sediments of Selected Coastal Beaches of Niger Delta, Southern Nigeria

A genome-wide association study identifies genetic determinants of hemoglobin glycation index with implications across sex and ethnicity.

We investigated the genetic determinants of variation in the hemoglobin glycation index (HGI), an emerging biomarker for the risk of diabetes complications. We conducted a genome-wide association study (GWAS) for HGI in the Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial (N = 7,913) using linear regression and additive genotype encoding on variants with minor allele frequency greater than 3%. We conducted replication analyses of top findings in the Atherosclerosis Risk in Communities (ARIC) study with inverse variance-weighted meta-analysis. We followed up with stratified GWAS analyses by sex and self-reported race. In ACCORD, we identified single nucleotide polymorphisms (SNPs) associated with HGI, including a peak with the strongest association at the intergenic SNP rs73407935 (7q11.22) (P = 5.8e-10) with a local replication in ARIC. In black individuals, the variant rs10739419 on chromosome 9 in the Whirlin (WHRN) gene formally replicated (meta-P = 2.2e-9). The SNP-based heritability of HGI was 0.39 (P< 1e-10). HGI had significant sex-specific associations with SNPs in or near GALNT11 in women and HECW2 in men. Finally, in Hispanic participants, we observed genome-wide significant associations with variants near USF1 and NXNL2/SPIN1. Many HGI-associated SNPs were distinct from those associated with fasting plasma glucose or HbA1c, lending further support for HGI as a distinct biomarker of diabetes complications. The results of this first evaluation of the genetic etiology of HGI indicate that it is highly heritable and point to heterogeneity by sex and race.

Spiral shaped highly sensitive rectangular PCF-based cancer cells detector in terahertz regime

Abstract The increasing fatality rate of cancer in the modern world has become a global concern. To address this issue, early detection of cancer cells in human blood is essential. In this article, a rectangular spiral shaped photonic crystal fiber has been proposed for sensing cancer cells in terahertz regime. The proposed PCF based sensor features a square shaped core surrounded by rectangular air holes of different sizes in a spiral manner. Finite element method based COMSOL Multiphysics software has been used for the design and analysis of the model. The model is sensitive to refractive index variation for the identification of cancer cells. The values of effective refractive index, effective mode area, relative sensitivity, non-linearity, and confinement loss are obtained for MCF-7, MDA-MB-231, Jurkat, HeLa, Basal and PC-12. The PCF based sensor resulted in excellent results of relative sensitivity and Confinement loss as good as 99.377% and 8.59 × 10−12 dBm−1 respectively. Furthermore, the present PCF based sensor model is fabrication feasible, and we hope that it can be utilized at industrial level for biosensing applications in terahertz waveguide regime.

A 3D DEM modeling of soil-rock mixture considering spatial distribution orientation of blocks

Spatial distribution orientations of blocks can cause significant errors in the discrete element model (DEM) calculation of soil-rock mixture (SRM). To avoid this error, spherical harmonic (SH) series whose harmonization degrees fixed at 15 were proposed for block reconstruction. This research refers to the case-history of a deep excavation rift valley spanning from the Mabian to Zhaojue section of the Leshan-Xichang Expressway, mainly containing moderately-weathered silty mudstone, in the Leshan City, Sichuan Province, China. The appropriate degree of finite-term SH series is selected by the volume, surface area. 100 blocks were scanned on site, and sphericity and angularity of the blocks were calculated. The sphericity and angularity of 50 reconstructed blocks were considered for the error analysis of SH method. Moreover, stochastic polyhedron method was considered for comparing different block reconstructions. The maximum block placement angle was defined to control the spatial distribution orientations of the blocks. Large scale direct tests were carried. Numerical simulations of large-scale direct shear tests were conducted to study the influence of the spatial distribution orientations of the blocks on the mechanical properties of the SRMs. The results revealed that the finite-term SH series fixed at 15 accurately reflected the shape characteristics and mechanical behaviors of actual blocks. The spatial distribution orientations of the blocks had a minimal impact on the friction angle and cohesion of SRM constructed through the SH method. The SRMs developed via the SH method exhibited marginal variations in contact force and anisotropy index of contact across diverse block placement strategies. The evolution of coordination number was closer when employing the SH method under varied block placement methods. Blocks reconstructed by the SH method, could mitigate errors in DEM calculation caused by the spatial distribution orientations of the blocks.

Diffusion-model-based inverse problem processing for optically-measured sound field

This paper proposes a diffusion-model-based method for addressing inverse problems in optical sound-field imaging. Optical sound-field imaging, known for its high spatial resolution, measures sound by detecting small variations in the refractive index of air caused by sound but often suffers from unavoidable noise contamination. Therefore, we present a diffusion model-based approach for sound-field inverse problems, including denoising, noisy sound-field reconstruction and extrapolation. During inference, sound-field degradation is introduced into the inverse denoising process, with range-null space decomposition used as a solver to handle degradation, iteratively generating degraded sound-field information. Numerical experiments show that our method outperforms other deep-learning-based methods in denoising and reconstruction tasks, and obtains effective results in extrapolation task. The experimental results demonstrate the applicability of our model to the real world.

Accommodating version of a schematic eye for emmetropia and myopia.

To develop an accommodating, wide-angle, schematic eye for emmetropia and myopia in which spectacle refraction and accommodation level are input parameters. The schematic eye is based on an earlier unaccommodated refraction-dependent eye for myopia developed by Atchison in 2006. This has a parabolic gradient index lens and parameters derived from biometric and optical measurements on young adults. Several parameters are linearly dependent upon spectacle refraction (anterior radius of curvature of the cornea, axial length and vertex radii of curvature and conic asphericities of a biconic retina). The new accommodated schematic eye incorporates accommodation-dependent changes in several lens-related parameters. These changes are based on literature values for anterior chamber depth, lens thickness, vitreous chamber depth, lens surface radii of curvature and lens front surface asphericity. A parabolic variation of refractive index with relative distance from the lens centre is retained, with the same edge and centre refractive indices as the earlier model, but the distribution has been manipulated to maintain focus near the retina for the emmetropic case at 0 and 4 D accommodation. The asphericity of the lens back surface is changed so that spherical aberration and peripheral refraction approximately match typical literature trends. The model is used to compare spherical aberration and peripheral refraction in eyes with up to 4 D of myopia and 4 D of accommodation. The levels of spherical aberration in the unaccommodated schematic eyes are similar to literature values for young adults, but the changes in spherical aberration with accommodation are approximately two-thirds of that found in an experimental study. As intended, peripheral refractions in the accommodated schematic eyes are similar to those of their unaccommodated counterparts. The wide-angle model extends the range of schematic eyes to include both refraction and accommodation as variable input parameters. It may be useful in predicting aspects of retinal image quality.

Design of an all-optical tunable 2D photonic crystal in As2S3 film

Amorphous arsenic trisulphide (As2S3) chalcogenide glass is widely used in photonics and optoelectronics due to its wide transparency in the infrared spectral range, its high linear refractive index (nAs2S3 = 2.42), which can be significantly modified by light with a suitable wavelength, and its important optical nonlinearity. In this work, we report the design of an all-optical tunable two-dimensional photonic crystal in a geometry which consists in a hexagonal lattice of holes patterned in As2S3 film with the aim to exhibit photonic band gap in the near infrared domain. We numerically investigated the possibility to all-optically tune the photonic band gap of an already patterned photonic crystal in As2S3 modifying only its refractive index by illumination with light of wavelength λ at the band gap energy (λ = 514.5 nm) or shorter, without affecting the lattice geometry. The influence of the variation of As2S3 refractive index (Δn) on the spectral position of the band gap and on its width has been determined for the light-induced modification of Δn up to the value of 0.09. For this value of Δn, a shift of almost 50 nm of the central wavelength of the photonic band gap has been obtained. These results are of great interest in the field of photonics offering a versatile solution to fabricate all-optical tunable photonic crystals in any optical material whose refractive index can be modified by light.

Metal-free ultrathin terahertz absorber with independently tunable dual narrow bands

Abstract A technique is introduced to precisely control the resonance behaviour of a metal-free graphene-based terahertz absorber by independently tuning dual resonant peaks. The proposed ultrathin absorber features a multilayer configuration, with two isolated resonator layers of patterned graphene on dielectric (SiO2) substrates, and a thin graphite sheet at the bottom serving as a reflector. The stacked arrangement enables independent tunability of the high-absorptivity resonant peaks at 7.33THz and 9.34THz. The structure, with a thickness of just λ/15 of the free-space wavelength, offers a compact design suitable for space-constrained applications. Its symmetrical geometry ensures polarization insensitivity and stable performance for incident angles up to 60°. Simulated results, analysed via CST Studio and validated with an Equivalent Circuit Model (ECM), demonstrate excellent thermal stability. Furthermore, the narrowband response of the proposed absorber improves its sensitivity for refractive index variations induced by biomolecular interactions validating its suitability in biosensing applications. The absorber demonstrates peak absorption across both the resonant frequencies with an analyte optimised at 1.5μm thickness. Sensitivity levels of 1.1THz/RIU and 1.05THz/RIU along with figure-of-merit (FOM) values of 2.11 and 2.23. are recorded for the lower and upper bands, respectively. The absorber offers enhanced selectivity owing to low values of full-width at half maximum (FWHM). High Q-factors of 12.85 and 19.3, confirm its strong potential for refractive index sensing. &amp;#xD;

Effects of Helicobacter pylori and Helicobacter pylori eradication on the microbiota of tongue coating

Eradicating Helicobacter pylori (H. pylori) can cause an imbalance in the microbiota. Dysbiosis of the gut microbiome may produce multiple diseases and bacterial infections. The objective of this study was to investigate the influence of Helicobacter pylori (H. pylori) infection and its eradication on the composition of the oral tongue coating microbiota. A cohort of 35 participants was recruited and categorized into two groups: the H. pylori negative group (N group) consisting of 12 individuals and the H. pylori positive group (23 individuals). Within the H. pylori positive group, subjects were further stratified into the H. pylori pre-eradicated group (HPQ group) and the H. pylori eradicated group (HPH group). H. pylori positive individuals were treated with a quadruple regimen containing bismuth, and tongue coating samples were collected both prior to and following treatment. Concurrently, tongue coating samples were collected from H. pylori negative individuals. High-throughput 16S rRNA sequencing technology was employed to assess the microbial composition of the tongue coating in the N group, HPQ group, and HPH group. Pertinent clinical data were documented.Microbial diversity was found to significantly differ among the N group, HPQ group, and HPH group, as evidenced by variations in Chao1 index, Shannon index, and Partial Least Squares Discriminant Analysis (PLS-DA). The dominant bacterial phyla identified across all groups included Bacteroidetes, Proteobacteria, Firmicutes, Fusobacteria, Actinobacteria, and Saccharibacteria. At the phylum level, Firmicutes exhibited higher relative abundance in the HPQ group in comparison to both the N group and HPH group. Conversely, Bacteroidetes displayed greater prevalence in the N group and HPH group. Linear Discriminant Analysis Effect Size (LEfSe) analysis indicated a higher abundance of Romboutsia, Rothia, and Turiciactor in the HPQ group. Our study revealed significant disparities in microbial diversity and richness among the three groups. Furthermore, our findings suggest a potential association between the presence of Streptococcus, Rothia and H. pylori positive individuals.

Greenland summer blocking characteristics: an evaluation of a high-resolution multi-model ensemble

AbstractAtmospheric blocking is a phenomenon that can lead to extreme weather events over a large region, yet its causes are not fully understood. Global climate models show limitations in representing Northern Hemisphere blocking, especially its frequency, and decadal variability in Greenland blocking in summer in the recent decades. In this study we evaluate the ability of high-resolution (HighResMIP) Earth System Models (ESMs) to simulate summer blocking over the Greenland area, using different but complementary methods to describe the characteristics of blocking. We find that the HighResMIP ensemble can reproduce the spatial pattern of Greenland blocking events, albeit with systematic biases, and capture the relative frequencies of the main blocking patterns: namely the wave breaking structure, North Atlantic ridge, and omega-type blocking. However, the HighResMIP ensemble fails to simulate the observed temporal variations of Greenland blocking index (GB2) and the extremely high values of daily GB2 observed in recent decades. In addition, we do not find clearly superior representation of blocking features from higher-resolution in HighResMIP models compared with lower-resolution models. We also find large sea surface temperature (SST) biases over the North Atlantic and seas surrounding Greenland, and biases in moisture transport over the North Atlantic toward Greenland, especially over the western flank of blocking areas, which might together contribute to model biases in the representation of blocking magnitude.

Numerical Analysis of Optical Fiber Refractive Index in the Miniaturized Graded‐Index Fiber Probe

ABSTRACTWe analyze the impact of the refractive index of optical fibers on the focusing properties of a miniaturized graded‐index (GRIN) fiber probe. The ABCD ray transfer matrix and characteristic parameters are employed to characterize the working distance, focusing spot size, and the depth of field effectively. The three‐dimensional (3‐D) function diagrams and two‐dimensional (2‐D) graphs are used to illustrate the impact of the no‐core fiber (NCF) refractive index and the center refractive index of GRIN fiber on the focusing properties. Numerical analysis results show that when the length of the NCF is 0.36 mm and the GRIN fiber is 0.1 mm, the variation of the refractive index of the NCF between 1.44 and 1.52 leads to the variation of the working distance in the range of 0.02 mm, while the focusing spot size varies in the range of 5 μm. A comparison of 12 probe samples reveals that a 0.02 difference in the center refractive index of GRIN fiber could result in a 0.16 mm variation in working distance and a variation in focusing spot size of over 3 μm. The experimental results indicate that alterations in the length of the fibers have a considerable effect on the focusing properties of the probe. In contrast, the range of variation in focusing properties with fiber refractive index is relatively limited.

Tectonic Activity Analysis of the Laji-Jishi Shan Fault Zone: Insights from Geomorphic Indices and Crustal Deformation Data

Fault segmentation plays a critical role in assessing seismic hazards, particularly in tectonically complex regions. The Laji-Jishi Shan Fault Zone (LJSFZ), located on the northeastern margin of the Tibetan Plateau, is a key structure that accommodates regional tectonic stress. This study integrates geomorphic indices, cross-fault deformation rate profiles, and 3D crustal electrical structure data to analyze the varying levels of tectonic activity across different segments of the LJSFZ. We extracted 160 drainage basins along the strike of the LJSFZ from a 30 m resolution digital elevation model and calculated geomorphic indices, including the hypsometric integral (HI), stream length-gradient index (SL), and channel steepness index (ksn), to assess the variations in tectonic activity intensity along the strike of the LJSFZ. The basins were categorized based on river flow directions to capture potential differences across the fault zone. Our results show that the eastern basins of the LJSFZ exhibit the strongest tectonic activity, demonstrated by significantly higher SL and ksn values compared to other regions. A detailed segmentation analysis along the northern Laji Shan Fault and eastern Jishi Shan Fault identified distinct fault segments characterized by variations in SL and ksn indices. Segments with high SL values (&gt;500) correspond to higher crustal uplift rates (~3 mm/year), while segments with lower SL values exhibit lower uplift rates (~2 mm/year), as confirmed by cross-fault deformation profiles derived from GNSS and InSAR data. This correlation demonstrates that geomorphic indices effectively reflect fault activity intensity. Additionally, 3D crustal electrical structure data further indicate that highly conductive mid- to lower-crustal materials originating from the interior of the Tibetan Plateau are obstructed at segment L3 of the LJSFZ. This obstruction leads to localized intense uplift and enhanced fault activity. These findings suggest that while the regional stress–strain pattern of the northeastern Tibetan Plateau is the primary driver of the segmented activity along the Laji-Jishi Shan belt, the direction of localized crustal flow is a critical factor influencing fault activity segmentation.

Determination of adipogenesis stages of human umbilical cord-derived mesenchymal stem cells using three-dimensional label-free holotomography

Adipogenesis involves complex changes in gene expression, morphology, and cytoskeletal organization. However, the quantitative analysis of live cell images to identify their stages through morphological markers is limited. Distinct adipogenesis markers on human umbilical cord-derived mesenchymal stem cells (UC-MSCs) were identified through holotomography, a label-free live cell imaging technique. In the MSC-to-preadipocyte transition, the nucleus-to-cytoplasm ratio (0.080 vs. 0.052) and lipid droplet (LD) refractive index variation decreased (0.149 % vs. 0.061 %), whereas the LD number (20 vs. 65) increased. This event was also accompanied by the downregulation and upregulation of THY1 and Preadipocyte Factor-1 (PREF-1), respectively. In the preadipocyte to immature adipocyte shift, cell sphericity (0.20 vs. 0.43) and LD number (65 vs. 200) surged, large LDs (>10 μm3) appeared, and the major axis of the cell was reduced (143.7 μm vs. 83.12 μm). These findings indicate features of preadipocyte and immature adipocyte stages, alongside the downregulation of PREF-1 and upregulation of Peroxisome Proliferator-Activated Receptor gamma (PPARγ). In adipocyte maturation, along with PPARγ and Fatty Acid-Binding Protein 4 upregulation, cell compactness (0.15 vs. 0.29) and sphericity (0.43 vs. 0.59) increased, and larger LDs (>30 μm3) formed, marking immature and mature adipocyte stages. The study highlights the distinct adipogenic morphological biomarkers of adipogenesis stages in UC-MSCs, providing potential applications in biomedical and clinical settings, such as fostering innovative medical strategies for treating metabolic disease.

Design and optimization of a polarization-insensitive terahertz metamaterial absorber for sensing applications

This study presents dual-band Terahertz (THz) metamaterial absorbers (MA) designed with square resonators for sensing applications. The absorber is made up of a plasmonic ring resonator, a middle polyimide layer, and a lower metal plate, which enhances its absorption capabilities. The position of annular strips and patch units is strategically adjusted to tune and optimize the absorber’s performance precisely. The proposed metamaterial (MA) consistently absorbs over 99 % within the frequency range from 1.4 to 2.8 THz at 1.6 THz for peak-1 and 2.3 THz for peak-2. The peaks labeled as ‘f1’ and ‘f2’ have a spectral width of 0.02 THz and high-quality factors (Q-factors) of 23 for peak-1 and 29 for peak-2, respectively. This makes them remarkably sensitive to variations in the environmental refractive index (RI). It is important to observe that the refractive index of most samples falls within the range of 1.0–2.0, highlighting the potential applications of this sensor.

The collapse of the Ming Dynasty actually began with the Wanli megadrought: Insights from a hydroclimate reconstruction based on tree-ring δ18O over the past 460 years

Climate change has played a pivotal role in shaping Chinese history, especially during the Ming Dynasty. Previous studies have focused primarily on the Chongzhen megadrought, which is widely considered as the primary climatic perturbation behind the demise of the Ming Dynasty. However, relatively little is known about other severe drought events and their potential impact on the dynasty collapse. Additionally, the characteristics of an exceptional climatic anomaly termed the “Late Ming Weak Monsoon Period” are unclear. In this study, we reconstructed the historical variations of Palmer Drought Severity Index for July–September based on tree-ring stable oxygen isotopes (δ18O) from 1556 CE to 2015 CE in southwest Chinese Loess Plateau. Our study reveals a significant weakening of the Asian summer monsoon between 1561 CE and 1661 CE, consistent with the Late Ming Weak Monsoon Period, and unravels its structural characteristics in detail. Our reconstruction also captures a distinct humidification trend over northwest China since the early 2000s. Notably, in addition to the well-known Chongzhen megadrought, our study records the severe Wanli megdrought (1585–1590 CE) during the late Ming Dynasty, an event that rarely featured in earlier studies, exhibiting comparable duration and severity to the Chongzhen megadrought. Further analysis indicates that Wanli megadrought may have served as an early trigger for the collapse of the Ming Dynasty. Furthermore, our analysis implicates the El Niño–Southern Oscillation as a contributing factor in both the Wanli and Chongzhen megadroughts, and thus to the ultimate collapse of the Ming Dynasty by affecting the Asian summer monsoon intensity.

Unraveling the complex dynamics of temporal moments for multispecies contaminant transport in saturated porous media: A global sensitivity analysis approach

In this study, we focus on the application of global sensitivity analysis (GSA) to gain insight into the influence of model parameters on the outputs of multispecies contaminant transport model. In this context, employing GSA methods (Morris and FAST) allows us to comprehend the relative significance of each input parameter in the model. We specifically analyzed the effects of model parameters on the concentration breakthrough curves and associated temporal moments of concentration of contaminant species. The spatial variability of sensitivity indexes from Morris and FAST methods for parent and daughter contaminant species is also investigated. We represent uncertainties of longitudinal dispersivity, porosity, first-order degradation constants of parent and daughter contaminant species, and sorption distribution coefficient of parent species into the coupled multispecies contaminant transport model and GSA framework. Our results show a complex interplay between different model parameters and their varying influences on different output metrics. The ranking of parameters based on GSA shows that (i) the contaminant mass recovery of final daughter species of three species chain reaction is governed by the first-order degradation coefficient of parent and first daughter species; (ii) dispersivity and porosity are critical parameters that govern the mean residence time and variance of breakthrough curve of final daughter species; (iii) the coefficient of skewness is more sensitive to dispersivity, sorption distribution coefficient, and first-order degradation coefficient of parent species as compared to other model parameters. The variation in the sensitivity indices among contaminant species and with travel distance is observed. This study highlights the significance of global sensitivity analysis when simulating the multiple species contaminants in saturated porous media.

Soil available phosphorus and pH are key factors affecting the site index of Larix kaempferi plantations in China

Assessing the quality of forest sites is crucial for evaluating the potential productivity of forests and formulating effective management strategies. Therefore, it is essential to understand how environmental variables affect the site quality. This study focuses on quantifying the effects of 44 different environmental variables including climate, topography, and soil properties on the site index of Larix kaempferi plantations in three different climate regions in China, utilizing the random forest algorithm. L. kaempferi site index was determined from stem analysis data by felling dominant trees from 51 even-aged stands. The results indicated that the proposed random forest model explained ~59.47% of site index variations. Among many environmental variables, available phosphorus, pH, degree-days above 5°C (DD5), and spring mean maximum temperature (Tmax_MAM) had significant effects on the site index (P &amp;lt; 0.05), and the importance of soil chemical properties generally exhibits relatively larger effects on the site index than climate variables and topography variables. The partial dependence analysis revealed that the L. kaempferi plantations had maximum values at ~30 mg/kg of available phosphorus in the first soil layers, 30 mg/kg of available phosphorus in the second soil layers, 20 mg/kg of available phosphorus in the third soil layers, the DD5 between 2,600and 3,000°C, and Tmax_MAM ~15°C. Our findings attempt to provide a better understanding of the site–growth relationship.

Impact of starch profile on glycemic index of coloured and non-pigmented genotypes of rice (Oryza sativa L.)

Abstract Rice serves as a crucial staple food, supplying energy and nutrients to roughly half the global population. Consumers prefer to take mostly the white rice, but pigmented rice is enriched with anthocyanin and has potential health benefits. The study of 27 rice genotypes consisting of eight non-pigmented and 19 pigmented genotypes were estimated for protein content, antioxidant activity and starch profile including total starch(TS), Resistant Starch(RS), Slowly Digestible Starch(SDS), Rapidly Digestible Starch(RDS), Amylose content(AC), and Glycemic Index (GI). This study shows that RS and SDS levels have a negative correlation with GI, whereas RDS has a positive association with the glycemic index. The starch content and amylose content were not showing any direct relation with the GI. There was minimal variation in the glycemic index between pigmented and non-pigmented rice varieties. Keywords: Antioxidant activity, glycemic index, pigmented rice, resistant starch, slowly digestible starch, starch profile

Fluorine fluid experimental determination of the refractive index, spectral and thermal variation, and transparency quantification of the MezzoCielo telescope

The MezzoCielo (or "half of the sky") is a telescope that aims to revolutionize the way astronomical observations are carried out: once operational, it will be able to continuously patrol the whole sky due to its extremely large field of view estimated to be around 104 square degrees, showing, at the same time, the spatial resolution required for scientific purposes. It is a monocentric optical device designed on the concept of an optical sphere; the latter requires the filling of its inner volume with special fluid in order to be actually convergent with a reasonable focal ratio (for spherical aberration reduction). This fluid must exhibit two main properties, namely, a low refractive index and an extremely high transparency in the visible range. In addition, many other characteristics are also required: thermal and chemical stability over time, no toxicity or flammability, and compatibility with glass and metals are some examples. On the basis of these considerations, two fluorine liquids have been selected: the fluids commercially known as FC-72, perfluorohexane with n d = 1.251 at T = 25°C, and Novec7200, ethoxy-nonafluorobutane with n d = 1.282 at T = 25°C. In this work, the experimental evaluation of their optical properties (refractive index and transparency) in the visible range and in the thermal interval [-10,+25]°C has been carried out in order to verify the data supplied by the manufacturer and to fully characterize their optical behaviour both spectrally and thermally. All the employed techniques have been firstly applied to commercial pure water, for which extensive literature could be used as reference for the procedures validation.