Soils with small variations in relief and under the same management system present differentiated spatial variabilities of their attributes. This variability is a function of soil position in the landscape, even if the relief has little expression. The aim of this work was to investigate the effects of relief shape and depth on spatial variability of soil chemical attributes in a Typic Hapludox cultivated with sugar cane at two landscape compartments. Soil samples were collected in the intercrossing points of a grid, in the traffic line, at 0-0.2 m and 0.6-0.8 m depths, comprising a set of 100 georeferenced points. The spatial variabilities of pH, P, K, Ca, Mg, cation exchange capacity and base saturation were quantified. Small relief shape variations lead to differentiated variability in soil chemical attributes as indicated by the dependence on pedoform found for chemical attributes at both 0-0.2 m and 0.6-0.8 m depths. Because of the higher variability, it is advisable to collect large number of samples in areas with concave and convex shapes. Combining relief shapes and geostatistics allows the determination of areas with different spatial variability for soil chemical attributes.