The temperature behavior of the spectral composition of luminescence of 3He-Zn plasma created by products of the nuclear reaction 3He(n, p)3T is studied. Metallic zinc was evaporated onto the side surface of a cell, which was irradiated in the core of an IRT nuclear reactor. The thermal-neutron flux density was 8 × 1011 neutrons/cm2 s. The cell was filled with helium 3 to a pressure of up to 650 Torr. Spectral studies were performed in the temperature range 70–650°C. At low temperatures (<300°C), luminescence was excited predominantly as a result of sputtering of the metallic film during its bombardment by protons with energies of 0.57 MeV, tritium nuclei with energies of 0.19 MeV, and components of helium plasma. At higher temperatures (above 420°C), luminescence was excited by fast particles in the bulk of a 3He-Zn vapor-gas mixture. It was found that, at temperatures of ∼260°C, in the presence of the film on the cell wall, Beutler lines of Zn II ion (λ = 589.4, 747.8, and 621.5 nm) and atomic lines at 307.59, 250.2 and 255.7 nm were anomalously highly excited. A model of plasmochemical processes for the vapor-gas mixture is considered, and results of numerical simulation of the luminescence are presented and compared with the measurement results.