Analytical methods for calculations of the transport machinery are often insufficient especially when untypical granular materials are considered. Discrete Element Method (DEM) is a very useful numerical tool supporting designing and optimization of the transport equipment. However, to obtain reliable DEM simulation results an accurate set of input parameters values is needed. The most common calibration approach is to make use of a procedure where laboratory tests are performed and then the same experiments are numerically replicated in DEM. The article presents calibration of the DEM input parameters on the example of perlite D18-DN Based on the performed calibration, the model of perlite transport in a screw conveyor has been shown.