Value Of Different Forms Research Articles

Longitudinal Relations Between Global Self-Esteem and Organizational Self-Esteem and Their Prospective Effects on Job Satisfaction and Work Engagement

Self-esteem represents one of the most important personal resources for workers. However, the value of different forms of self-esteem (i.e., global vs. organization-specific) for work outcomes and their reciprocal associations over time have yet to be examined. This preregistered study examined (1) longitudinal reciprocal relations between global and organizational self-esteem, (2) prospective effects of global and organizational self-esteem on job satisfaction and work engagement, and (3) the role of organizational self-esteem as a mediator of the effects of global self-esteem on job satisfaction and work engagement. Using data on 1014 workers who were assessed annually during the first three years of their careers, we implemented three cross-lagged panel (CLPM) models: the traditional CLPM, the Random Intercept-CLPM, and the Latent State Trait Model. The results from the best fitting model (the Latent State Trait Model), as well as the other two, failed to support our preregistered hypotheses; instead, the findings suggest that global and organizational self-esteem are largely independent, at both the between- and within-person level, and that neither form of self-esteem has important effects on job satisfaction or work engagement.

Prognostic value of different forms of serum MMP-2 and MMP-9 in dogs with mammary tumors; a longitudinal study

Gelatinases (MMP-2 and MMP-9) are related to tumor invasion and metastasis. In humans, the diagnostic value of serum levels of gelatinases has been confirmed in breast cancer, but their diagnostic value in canine mammary tumors is still unknown. This study aimed to determine the serum level of gelatinases in dogs with mammary tumors in order to determine their value in the diagnosis of malignancy or benign tumors and also in predicting the possibility of metastasis and recurrence. Frequent measurement of MMP-2 and MMP-9 by gelatin zymography in serum before and after surgical treatment has not previously been studied for monitoring mammary tumors in dogs. Thus, the serum levels of MMP-2 and MMP-9 in 26 dogs with mammary tumors before surgical treatment and then 1, 4 and 12 months after surgery were evaluated by gelatin zymography. Serum samples of 26 healthy dogs with normal conditions were used as control.Dogs with benign and malignant mammary tumors showed bands of pro-MMP-2, pro-MMP-9 and active MMP-9. However, only pro-MMP-2 and pro-MMP-9 bands appeared in the serum of control group. Our results showed that the presence of active MMP-9, regardless of its level, was prognostically important for metastasis and or recurrence (M/R). However, the presence of active MMP-2 band was more important for M/R than active MMP-9, as its presence coincides with definitive M/R. It seems that serum gelatin zymography could possibly be used at regular intervals before and after surgery to evaluate the probability of M/R in dogs with mammary tumors. More research is needed in this regard.

Vacant or viable?

Beginning with Boeren’s (2018) or Rubenson & Elfert’s (2019) claims of under-recognition of quantitative methodology in adult education, authors use the ecological niche from biology as a metaphorical and heuristic model in order to consider the mechanisms determining the viability of research methodologies in education for adults. The authors discuss ecosystem factors affecting research methodologies and consider the situations of Germany and Canada to illustrate application of the niche metaphor. The conclusion stresses the complementary relevance and integrative value of different forms of research. Addressing diverse questions requires diverse methodologies and a rich ecosystem of resources and research capabilities.

Kin, friends, philanthronationalists: “Relations” as a modality of colonial and post-colonial charity in Sri Lanka

Through an historical ethnographic analysis of Sri Lanka’s oldest charity, the Colombo Friend-in-Need Society, this article explores changing modalities of humanitarian “relations” in colonial and post-colonial contexts. For two hundred years, “the Society” would provide a model of liberal humanitarianism premised on “friendship,” a civil and secular relation that the organisation distinguished from “kinship” on the one side and “religion” on the other. Sorting and ranking kinds of charitable practice according to their relations became a project through which the elite could establish the relative values of different forms of mutuality and autonomy and their contribution to colonial and post-colonial development. Paying attention to the Society’s role in this process also helps to reveal the historical contingencies of “relation” as a foundational anthropological concept and analytical objective.

From the What to the How of Keeping 1.5°C Alive: Methodological Innovations

Much attention is rightly being devoted to what cities need to do and the targets they need to meet in order to fulfill the 1.5°C agenda. The field of technical innovation is also vibrant, with bold marketing of new solutions a daily occurrence. Adopting them uncritically or in inappropriate contexts can often incur great expense and create technological lock-ins and path dependencies without sufficient positive impacts. By contrast, comparatively little innovation is occurring in methods to understand how changes and innovations might be received by different groups of urban residents or, indeed, what their often conflicting perceptions and priorities are in relation to individual and collective behavioural changes in adapting to climate change and promoting urban sustainability and resilience. This intervention explains some of the innovative methods available that have recently been tried and tested in diverse urban contexts. These involve bringing different stakeholders together to build shared understandings of local problems and to explore and co-produce appropriate strategies and solutions. These constitute deep and extended forms of participation that recognize the value of different forms of knowledge and seek to address unequal power relations rather than assuming that experts know best. On the basis of extensive comparative research, guidelines of good practice and how to adapt methods to local contexts have been developed. This article summarizes these guidelines and signposts to the full manual available on open access.

Scoping Review of Curricula and Pedagogical Approaches for Physiotherapist Performed Point of Care Ultrasonography.

This study collates and maps physiotherapy pre- and post-licensure curricula and pedagogical approaches for point of care ultrasonography (POCUS). We used a standardized scoping review methodology and reporting framework. A total of 18,217 titles and abstracts, and 1,372 full text citations were screened, with 209 studies classified as physiotherapist performed POCUS. Of the 209 studies, 15 evaluated pre- and post-licensure curricula and pedagogical approaches. Seventy-two to 98% of pre-licensure programs reported including theoretical knowledge of POCUS and 44-45% reported practical teaching or competency assessment. In post-licensure studies of POCUS, 0-61% of physiotherapists reported training for POCUS. All studies of post-licensure pedagogical approaches included an assessment of theoretical knowledge of POCUS, but only one study included a practical assessment of competency. There was considerable variability in POCUS methods and duration of pedagogical approaches. Except for one study, all pedagogical approaches reported improvement in theoretical knowledge. Progress in physiotherapy-specific, standardized, competency-based curricula and pedagogical approaches in POCUS has been limited, with minimal research available, and considerable variability both pre- and post-licensure. These findings could be used to advocate for the inclusion of POCUS in pre- and post-licensure physiotherapy curriculum, and suggest a need for clear guidelines from regulatory colleges and licensing bodies, and a common terminology for physiotherapist performed POCUS. Future directions for research include a systematic review of the psychometric properties of physiotherapist performed POCUS within and across anatomical areas, an assessment of value of different forms of training, and an evaluation of the impact of physiotherapist performed POCUS on patient outcomes.

Nuclear expression of pSTAT3Tyr705 and pSTAT3Ser727 in the stromal compartment of localized hormone-naïve prostate cancer

BackgroundThe signal transducer and activator of transcription 3 (STAT3) is involved in the progression of different tumors including prostate cancer (PCa). The expression of STAT3 in benign and malignant epithelium has been described previously but it has not been described in the stromal compartment. The aim of the present study was to evaluate the nuclear expression and prognostic value of different forms of phosphorylated STAT3 in the stromal compartment of non-cancer and cancer areas of prostatic tissue. Material and methodsTissue microarray cores from radical prostatectomy of 225 patients with hormone-naïve localized PCa were immunostained for two phosphorylated forms of STAT3, pSTAT3Tyr705 and pSTAT3Ser727. The prognostic value of the expression levels was studied by Cox regression analysis and biochemical recurrence (BCR)-free survival illustrated by Kaplan-Meier curves. ResultsExpression of pSTAT3Tyr705 and pSTAT3Ser727 in the stromal compartment of cancer tissue was lower compared with non-cancer areas. In univariable and multivariable Cox regression analysis, expression levels of pSTAT3Tyr705 and STAT3Ser727 showed similar prognostic value as pathological T-stage, Gleason score and surgical margin status. Kaplan–Meier survival analysis showed that low nuclear expression levels of pSTAT3Tyr705 and pSTAT3Ser727 in stromal cells in cancer compartment and in non-cancer areas were related to BCR-free survival. ConclusionsNuclear expression of pSTAT3Tyr705 and pSTAT3Ser727 in the stromal cells mirrors previous findings in the epithelial component in that it displays prognostic value in men undergoing radical prostatectomy for localized hormone-naïve PCa.

Vrednosti različitih tipova kiselosti pseudogleja u Kraljevačkoj kotlini pod šumom, livadom i oranicama

This paper presents the results of active (pH in H2O), exchangeable (pH in KCl), hydrolytic (Y1) and total acidity (T-S) in humus-accumulative (Ah, Ahp) and subsurface (Eg, Btg) horizons of Pseudogley Soils in Kraljevo Basin for 14 soil profiles excavated in forests, 16 in meadows and 24 on arable land. The results showed that acidification was weaker or more pronounced in all three most important tested horizons of Pseudogley Soils, and that the differences in the value of different forms of acidity existed among forest, meadow and arable land uses, as well as between the horizons of the same profile. The chemical reaction of soil solution ranged from very weak to extremely acid. The highest active acidity was found in forest profiles, especially in deeper horizons. Exchangeable acidity ranged from 3.7 to 4.9 pH units, with the forest profiles as the most acid, while the differences between meadow and arable land were less pronounced. The highest hydrolytic acidity was obtained in the forest profiles, while acidity in meadow and arable profiles was significantly lower and the lowest, respectively. Total acidity of the Kraljevo pseudogleys ranged from 6.2 to 24.8 meq/100 g soil and similarly to hydrolytic acidity, the value of total acidity was affected by the land use.

How is high quality research evidence used in everyday decisions about induction of labour between pregnant women and maternity care professionals? An exploratory study

ObjectiveTo explore the use of high quality research evidence in women's and maternity care professionals’ decisions about induction of labour (IOL). MethodsA qualitative study underpinned by a social constructionist framework, using semi-structured interviews and generative thematic analysis. SettingA large tertiary referral maternity unit in northern England in 2013/14. Participants22 randomly selected health care professionals involved in maternity care (midwives, obstetricians, maternity service managers), and 16 postnatal women, 3-8 weeks post-delivery, who were offered IOL in their most recent pregnancy. FindingsThree themes were identified in the data; (1) the value of different forms of knowledge, (2) accessing and sharing knowledge, and (3) constrained pathways and default choices. Findings echo other evidence in suggesting that women do not feel informed about IOL or that they have choices about the procedure. This study illuminates potential explanatory factors by considering the complex context within which IOL is discussed and offered (e.g. presentation of IOL as routine rather than a choice, care pathways that make declining IOL appear undesirable, blanket use of clinical guidelines without consideration of individual circumstances and preferences). Key conclusionsThis study suggests that organisational, social, and professional factors conspire towards a culture where (a) IOL has become understood as a routine part of maternity care rather than an intervention to make an informed choice about, (b) several factors contribute to demotivate women and health care practitioners from seeking to understand the evidence base regarding induction, and (c) health care professionals can find themselves ill-equipped to discuss the relative risks and benefits of IOL and its alternatives. Implications for practiceIt is important that IOL is recognised as an optional intervention and is not presented to women as a routine part of maternity care. When IOL is offered it should be accompanied by an evidence informed discussion about the options available to support informed decision making. Health care professionals should be supported to understand the evidence base and our findings suggest that any attempt to facilitate this needs to acknowledge and tackle complex organisational, social and professional influences that contribute to current care practices.

Classical Nature: Natural History, Classical Humanism, and the Value of Knowledge in Sweden, 1800–1850

This article investigates a series of attempts to imbue natural history with humanistic values and align its epistemological goals with those of classical studies in Sweden during the first half of the nineteenth century. By tracing the claims made by a group of twenty-one natural scientists, physicians, and state officials as well as others who took up the cause in response to a government proposal for a new school ordinance, this paper demonstrates how natural history became linked to self-cultivation and edification (Bildung, or bildning in Swedish) while the material and practical utility it was once so strongly associated with was downplayed in favor of moral development. It argues that a knowledge regime favoring the humanities in general and classical studies in particular strongly influenced secondary education, leading the group to claim that the study of nature should be treated as part of classical education. Although their argumentation subordinated the natural sciences to the humanities, they and later advocates accepted the new knowledge regime as they were themselves part of an academic culture of classical humanism. The key role that natural history played in this struggle over the educational and social value of different forms of knowledge during this period demonstrates that the history of science can be enriched by including the historical impact of the humanities on the natural sciences.

SCIENCE AND TECHNOLOGY IN ENGLAND AND WALES: THE LOST OPPORTUNITY OF THE COLLEGES OF ADVANCED TECHNOLOGY

ABSTRACT This paper focuses on the Colleges of Advanced Technology (CATs), specialist providers of advance science and technology which existed in England and Wales for ten years after the 1956 White Paper Technical Education. Its central argument is that recasting the CATs as broader-based universities following the 1963 Robbins Report was a significant error which attenuated the progress of science and technology, and prevented the Colleges’ development as viable providers of higher education (HE) outside the university sector. This decision, it is argued, was shaped by typically English views about the relative value of different forms of learning, the nature and purpose of HE, and particular beliefs about the primacy of the university. It also conflated the general desire to increase participation in higher education with the wish to promote science and technology in particular. A bolder option, it is proposed, would have been to build the CATs up as prestigious institutes of technology, along the lines of those found in the USA and continental Europe – although this, it is recognised, would have entailed a substantial shift in the role of the state and reduced the individual and collective autonomy of HE institutions in England and Wales.

The central role of Inuit Qaujimaningit in Nunavut’s impact assessment process

ABSTRACT In impact assessment (IA) the value of different forms of knowledge is increasingly acknowledged, but implementation and practice challenges continue. In Nunavut, a territory in the Canadian Arctic, Indigenous knowledge plays a key role in understanding and defining environmental baselines and guiding the assessment process; however, even here there are needs and opportunities for improved treatment and use of Indigenous knowledge in assessment and decision-making. This paper outlines the central role of Inuit Qaujimaningit/Qaujimajatuqangit (IQ) (Inuit knowledge) in shaping and defining Nunavut’s impact assessment process. The work highlights the potential of the Nunavut process to provide a model for the use of Indigenous knowledge in IA, and of co-management or Indigenous-led impact assessment. Focus groups were held with board members and staff of the Nunavut Impact Review Board – the co-management board responsible for impact assessment in the territory. The results highlight the unique qualities of the impact assessment process in Nunavut and demonstrate how IQ is a crucial component of project review, notably its role in decision-making and for ensuring that the process is meaningful to communities. The results and recommendations have value to a range of other jurisdictions that are also working towards using Indigenous knowledge in environmental decision-making or even seeking to advance Indigenous-led impact assessment.

Vocational education and training for African development: a literature review

ABSTRACT The SDGs mark the clearest global acceptance yet that the previous approach to development was unsustainable. In VET, UNESCO has responded by developing a clear account of how a transformed VET must be part of a transformative approach to development. It argues that credible, comprehensive skills systems can be built that can support individuals, communities, and organisations to generate and maintain enhanced and just livelihood opportunities. However, the major current theoretical approaches to VET are not up to this challenge. In the context of Africa, we seek to address this problem through a presentation of literatures that contribute to the theorisation of this new vision. They agree that the world is not made up of atomised individuals guided by a “hidden hand”. Rather, reality is heavily structured within political economies that have emerged out of contestations and compromises in specific historical and geographical spaces. Thus, labour markets and education and training systems have arisen, characterised by inequalities and exclusions. These specific forms profoundly influence individuals’ and communities’ views about the value of different forms of learning and working. However, they do not fully define what individuals dream, think and do. Rather, a transformed and transformative VET for Africa is possible.

Almond Form and Processing Impacts Metabolizable Energy Value in Humans

We have previously demonstrated that the metabolizable energy (ME) of whole roasted almonds is less than that predicted by the Atwater factors, and thus lower than the value currently listed on the Nutrition Facts panel. Studies have shown that incomplete disruption of the cell wall during mastication of whole almonds leads to decreased lipid absorption, suggesting that the food matrix plays a role in determining the ME value of a food. However, data are lacking on how food structure and processing (roasting, slicing or grinding) impact the ME value of almonds. The objective of this research was to determine the ME value of different forms of almonds.We conducted a randomized, crossover design study in healthy individuals (n = 18) to measure the ME of the following forms of almonds, within the context of a completely controlled diet (18 days each): whole, natural almonds (42 g/day); whole, roasted almonds (42 g/day); diced almonds (42 g/day); almond butter (42 g/day); and control (0 g/day). After 9 days of adaptation to each diet, participants collected all urine and fecal samples for approximately 9 days. The gross energies of the diets, almonds, urine, and feces were measured by adiabatic bomb calorimetry. The ME value of the nuts was determined using the paired‐diet approach.Based on the measured chemical composition of the almonds fed, the estimated ME (kcal/g) by use of Atwater specific factors for whole natural almonds, whole roasted almonds, diced almonds, and almond butter was 5.91, 6.01, 6.04, and 6.18, respectively. The empirically measured ME value (kcal/g) for whole natural almonds, whole roasted almonds, and diced almonds was 4.42, 4.86, and 5.04, significantly lower than predicted (P < 0.001 for all); while the ME for almond butter was similar to predicted (6.53 kcal/g; P = 0.08). Available calories from almonds is dependent on the form in which they are consumed. Furthermore, the measured ME of whole natural almonds, whole roasted almonds, and diced almonds is significantly lower than that estimated by the Atwater factors (30.4%, 24.5%, and 22.1%, respectively).Atwater factors (general or specific) provide inaccurate estimates of ME for almonds whether they are consumed whole, whole roasted, or chopped, whereas they are accurate for butter. It is likely that estimates of macronutrient digestibility used to develop the Atwater factors are incorrect for nuts.Support or Funding InformationUSDA and Almond Board of California

Diplomacy and audit: Technologies of knowledge in Europe

This article investigates diplomatic knowledge production in Europe—mostly in European Union institutions but also in the member states—to probe the role of audit culture in that professional field. Diplomatic knowledge refers to the knowledge about places that is produced by career diplomats; audit culture refers to a form of regulatory power that shapes thought and action through the continuous application of measurable standards. Empirically, the analysis draws from nearly one hundred interviews with policy professionals, mostly but not exclusively in Brussels, to examine the play of qualitative and intangible skills in diplomatic work. Conceptually, it foregrounds the growing impact of audit in that sphere. I observe the narratives of efficiency, economy, and flexibility in European diplomacy, and I highlight tensions around the value of different forms of knowledge in the profession. By foregrounding the intellectual and creative facets of diplomatic work and by examining the impact of audit culture on the profession, the article helps us understand how diplomats produce knowledge about the world. It thereby enriches geographical scholarship on geopolitical knowledge and policy processes.

Poly-victimization among girls in the justice system: trajectories of risk and associations to juvenile offending.

Life History Calendars and the Juvenile Victimization Questionnaire were used to collect data from 100 delinquent girls to (a) examine range and co-occurrence of different types of violence over the life span, (b) examine independent and cumulative trajectories of risk for varied types of victimization, and (c) examine the relationship of victimization to girls' offending. Risk trajectories demonstrate critical risk periods for different forms of violence exposure. Cox regression was used to examine the predictive value of different forms of violence exposure for the onset of delinquent and criminal behavior. Findings illuminate the need for programs addressing substance use and alternative coping mechanisms.

The need to disentangle key concepts from ecosystem-approach jargon.

The ecosystem approach—as endorsed by the Convention on Biological Diversity (CDB) in 2000—is a strategy for holistic, sustainable, and equitable natural resource management, to be implemented via the 12 Malawi Principles. These principles describe the need to manage nature in terms of dynamic ecosystems, while fully engaging with local peoples. It is an ambitious concept. Today, the term is common throughout the research and policy literature on environmental management. However, multiple meanings have been attached to the term, resulting in confusion. We reviewed references to the ecosystem approach from 1957 to 2012 and identified 3 primary uses: as an alternative to ecosystem management or ecosystem-based management; in reference to an integrated and equitable approach to resource management as per the CBD; and as a term signifying a focus on understanding and valuing ecosystem services. Although uses of this term and its variants may overlap in meaning, typically, they do not entirely reflect the ethos of the ecosystem approach as defined by the CBD. For example, there is presently an increasing emphasis on ecosystem services, but focusing on these alone does not promote decentralization of management or use of all forms of knowledge, both of which are integral to the CBD’s concept. We highlight that the Malawi Principles are at risk of being forgotten. To better understand these principles, more effort to implement them is required. Such efforts should be evaluated, ideally with comparative approaches, before allowing the CBD’s concept of holistic and socially engaged management to be abandoned or superseded. It is possible that attempts to implement all 12 principles together will face many challenges, but they may also offer a unique way to promote holistic and equitable governance of natural resources. Therefore, we believe that the CBD’s concept of the ecosystem approach demands more attention.La Necesidad de Desenredar Conceptos Clave del Argot Ambiente-EstrategiaResumenLa estrategia ambiental – como es promocionada por la Convención Biológica sobre Diversidad en 2000 – es una estrategia para un manejo holístico, sustentable y equitativo de recursos naturales, que habrá de implementarse por vía de los 12 Principios de Malawi. Estos principios describen la necesidad de manejar la naturaleza en términos de ecosistemas dinámicos, mientras se compromete totalmente con las personas locales. Es un concepto ambicioso. Hoy en día, el término es común en la investigación y la literatura de políticas sobre el manejo ambiente. Sin embargo, se han relacionado múltiples significados con el término, lo que resulta en confusión. Revisamos referencias a la estrategia ambiental de 1957 a 2012 e identificamos tres usos principales: como una alternativa para manejo ambiental o basado en ecosistemas; en referencia a una estrategia integrada y equitativa para el manejo de recursos según la CBD; y como un término que indica un enfoque en el entendimiento y la valuación de los servicios ambientales. Aunque los usos de este término y sus variantes pueden traslaparse en su significado, típicamente no reflejan en su totalidad los valores de la estrategia ambiental como fue definida por la CBD. Por ejemplo, actualmente hay un énfasis creciente en los servicios ambientales, pero enfocarse solamente en estos no promueve la descentralización del manejo o el uso de todas las formas de conocimiento, siendo ambas integrales para el concepto de la CBD. Resaltamos que los Principios de Malawi están en riesgo de ser olvidados. Para entender mejor estos principios, se requiere de más esfuerzo para implementarlos. Dichos esfuerzos deben ser evaluados, idóneamente con estrategias comparativas, antes de permitir que el concepto de la CBD de manejo holístico y comprometido socialmente sea abandonado o reemplazado. Es posible que los intentos por implementar los 12 principios juntos enfrentarán muchos obstáculos, pero también pueden ofrecer una forma única de promover el gobierno holístico y equitativo de los recursos naturales. Así, creemos que el concepto de estrategia ambiental de la CBD exige mayor atención.

Leadership and branding in business schools: a Bourdieusian analysis

This paper explores the growth of corporate branding in higher education (HE) and its use by academic and professional managers as a mechanism for not only enhancing institutional reputation but also for facilitating internal culture change. It uses Bourdieu's framework of field, capital and habitus to analyse case studies of branding in two English business schools from the perspectives of academics, management and professional staff and students. The findings reveal a number of tensions and inconsistencies between the experiences of these groups that highlight the contested nature of branding in HE. In an era of rankings, metrics and student fees, it is suggested that branding has become an important means through which HE leaders and managers (re)negotiate the perceived value of different forms of capital and their relative positions within the field. Whilst branding operates at a largely ideological level it has a material effect on the allocation of power and resources within institutions. This is an important development in a sector that has typically privileged scientific capital and contributes towards an understanding of the ways in which leadership is ‘distributed’ within universities.

Teacher Training Qualifications For The Lifelong Learning Sector – A Comparison Of Higher Education Institution And Awarding Body Qualifications

This paper focuses on Initial Teacher Training (ITT) for the Lifelong Learning Sector (LLS) in England. Based on research with teachers and Teacher Educators at four different Lifelong Learning sites, it explores the relative value of different forms of ITT, offered by Higher Education Institutions (HEIs) and alternative awarding bodies. It shows that, whilst the majority of respondents regard awarding body courses as adequate, most perceive HEI programmes to be superior to other forms of teacher training – both in terms of labour market currency and the quality of learning provided.

Prognostic value of reported chest pain for cardiovascular risk stratification in primary care

The prognostic significance of chest pain is well established in patients with coronary artery disease, but still ill defined in primary prevention. Therefore, the aim of our analysis was to assess the prognostic value of different forms of chest pain in a large cohort of primary care subjects under the conditions of contemporary modalities of care in primary prevention, including measurement of serum levels of the biomarker NT-pro-BNP. We carried out a post-hoc analysis of the prospective DETECT cohort study. In a total of 5570 unselected subjects, free of coronary artery disease, within the 55,518 participants of the cross-sectional DETECT study, we assessed chest pain history by a comprehensive questionnaire and measured serum NT-pro-BNP levels. Three types of chest pain, which were any chest pain, exertional chest pain and classical angina, were defined. Major adverse cardiovascular events (MACEs = cardiovascular death, myocardial infarction, coronary revascularization procedures) were assessed during a 5-year follow-up period. During follow-up, 109 subjects experienced a MACE. All types of reported chest pain were associated with an approximately three-fold increased risk for the occurrence of incident MACEs, even after adjusting for cardiovascular risk factors. Any form of reported chest pain had a similar predictive value for MACEs as a one-time measurement of NT-pro-BNP. However, adding a single measurement of NT-pro-BNP and the information on chest pain resulted in reclassification of approximately 40% of subjects, when compared with risk prediction based on established cardiovascular risk factors. In primary prevention, self-reported chest pain and a single measurement of NT-pro-BNP substantially improve cardiovascular risk prediction and allow for risk reclassification of approximately 40% of the subjects compared with assessing classical cardiovascular risk factors alone.