Distance Values Research Articles

Significance of tibial-tubercle trochlear groove distance and adjunctive radiological parameters in patients with recurrent patellar instability.

Magnetic resonance imaging (MRI) is often used to evaluate patients with patellar dislocations to facilitate diagnosis and management strategies. Many radiological parameters have been described in the literature. The aim of this study was to assess the significance of tibial-tubercle trochlear groove distance (TT-TG) distance and other MRI measurements in patients with and without patellar instability. This case-control study included 41 patients with recurrent patellar instability and 50 patients with stable knees, all of whom underwent MRI scans. A total of 19 radiological parameters were measured in both groups. All measured MRI parameters had statistically significant differences between both groups (p < 0.05) apart from trochlear cartilage length. TT-TG distance. 20mm had the strongest association with patellar instability (OR 53.3, p = 0.006, 95%CI [3.1- 927.4]) and the highest specificity (100%) but had the lowest sensitivity (34%) out of all the measured parameters. TT-TG. 13mm had a higher sensitivity (68%) but lower specificity (72%) and weaker association with patellar instability (OR 5.5, p < 0.001, 95%CI [2.2. 13.7]). TT-TG/trochlear articular cartilage width ratio also had a strong association with patellar instability (OR 14.7, p < 0.001, 95%CI [4.5. 48.5]) with high specificity (92%) but lower sensitivity (56%). The cut-off values for TT-TG distance at 13mm and 20mm both had advantages and disadvantages which supports the concept of using patient-individualised ratios. Patellar instability is associated with many radiological abnormalities demonstrated on MRI scans. Selection of the most appropriate measurement is dependent on the philosophy and preference of the treating clinician.

Age-optimized cut-off values for pubofemoral distances in screening for hip dysplasia.

To establish cut-off values for lateral pubofemoral distance (PFD) measurements for detecting hip dysplasia in early (four days) and standard care (six weeks) screening for developmental dysplasia of the hip (DDH). All newborns, during a one-year period (October 2021 to October 2022), were offered a PFD ultrasound (US) examination in addition to the existing screening programme for DDH. Newborns who were referred for standard care hip US, suspected for DDH, received a secondary PFD US examination in conjunction with the standard care Graf/Harcke hip US examination. Receiver operating characteristic curves and empirically optimal cut-off values were calculated with a true positive defined as a Graf type ≥ IIc hip. We included 2,735 newborns, of whom 758 received both early PFD hip US and standard care Graf/Harcke hip US. For early (four days) PFD screening, the optimal cut-off point was calculated to be 6.2 mm (95% CI 4.7 to 7.7) producing a sensitivity of 80% (95% CI 55% to 100%) and a specificity of 87% (86% to 89%). For PFD screening performed at standard care (six weeks) hip US, the optimal cut-off point was calculated to be 5.6 mm (95% CI 4.9 to 6.3) producing a sensitivity of 100% (95% CI 100% to 100%) and a specificity of 96% (95% CI 95% to 97%). PFD US screening produces a high degree of both sensitivity and specificity for detecting DDH. Age-specific cut-off values should be used to heighten the accuracy of PFD US screening.

Hybrid deep learning based stroke detection using CT images with routing in an IoT environment

ABSTRACT Stroke remains a leading global health concern and early diagnosis and accurate identification of stroke lesions are essential for improving treatment outcomes and reducing long-term disabilities. Computed Tomography (CT) imaging is widely used in clinical settings for diagnosing stroke, assessing lesion size, and determining the severity. However, the accurate segmentation and early detection of stroke lesions in CT images remain challenging. Thus, a Jaccard_Residual SqueezeNet is proposed for predicting stroke from CT images with the integration of the Internet of Things (IoT). The Jaccard_Residual SqueezeNet is the integration of the Jaccard index in Residual SqueezeNet. Firstly, the brain CT image is routed to the Base Station (BS) using the Fractional Jellyfish Search Pelican Optimization Algorithm (FJSPOA) and preprocessing is accomplished by median filter. Then, the skull segmentation is accomplished by ENet and then feature extraction is done. Lastly, Stroke is detected using the Jaccard_Residual SqueezeNet. The values of throughput, energy, distance, trust, and delay determined in terms of routing are 72.172 Mbps, 0.580J, 22.243 m, 0.915, and 0.083S. Also, the accuracy, sensitivity, precision, and F1-score for stroke detection are 0.902, 0.896, 0.916, and 0.906. These findings suggest that Jaccard_Residual SqueezeNet offers a robust and efficient platform for stroke detection.

Dynamic in vivo monitoring of granum structural changes of Ctenanthe setosa (Roscoe) Eichler during drought stress and subsequent recovery.

Investigating the effects of drought stress and subsequent recovery on the structure and function of chloroplasts is essential to understanding how plants adapt to environmental stressors. We investigated Ctenanthe setosa (Roscoe) Eichler, an ornamental plant that can tolerate prolonged drought periods (40 and 49 days of water withdrawal). Conventional biochemical, biophysical, physiological and (ultra)structural methods combined for the first time in a higher plant with in vivo small-angle neutron scattering (SANS) were used to characterize the alterations induced by drought stress and subsequent recovery. Upon drought stress, no significant changes occurred in the chloroplast ultrastructure, chlorophyll content, 77K fluorescence emission spectra and maximal quantum efficiency of PSII (Qy dark), but the actual quantum efficiency of PSII (Qy light) decreased, the amounts of PSI-LHCII complexes and PSII monomers declined, and that of PSII supercomplexes increased. Thickness of the leaf and of the adaxial hypodermis, chloroplast length and granum repeat distance (RD) values decreased upon drought stress, as shown by light microscopy and SANS, respectively. Because of the very slight (nm-range) changes in RD values, the large biological variability (significant differences in RD values among the leaves and studied leaf regions) and the invasive sampling required for this method, transmission electron microscopy (TEM) hardly showed significant differences. On the other side, in situ SANS analyses provided a unique insight in vivo into the fast structural recovery of the granum structure of drought-stressed leaves, which happened already 18 h after re-watering, while functional and biochemical recovery took place on a longer time scale.

Full-Arch Digital Implant Impression Trueness: An in Vivo Study.

To evaluate the trueness of maxillary and mandibular full-arch implant digital impressions with and without additional reference objects. Seventeen maxillary and 6 mandibular arches with four implants were randomly divided into a group with additional reference objects (wRO group, n = 12) and without them (woRO group, n = 11) and scanned with an intraoral scanner (IOS). For each jaw, the control model (CM) data was obtained to evaluate the deviations in the scan body positions in the wRO and woRO groups. CM and IOS data sets were imported into metrology software for distance and angle measurements between scan body pairs 1-2, 1-3, and 1-4. Unsigned values of distance and angle data differences between CM and IOS groups were used for further analysis. The highest statistically significant (p < 0.05) differences between distance and angulation measurements of the maxilla and mandible were observed in the 1-4 scan body pair group (136 ± 95 μm, 0.95° ± 0.79°; 362 ± 233 μm, 2.22° ± 2.11°, respectively). Distance deviations of the mandible were higher in all scan body pair groups. The woRO group had higher distance and angulation unsigned trueness values than in the wRO group, especially in the 1-4 scan body pair (224 ± 183 μm, 1.77° ± 1.76°;169 ± 162 μm, and 0.83° ± 0.57°, respectively). IOS for the full-arch cases had statistically and clinically significant distance and angle deviations. Higher deviations were observed in the single mandibular scan body pair. The tendency of diminished distance and angular deviations with the utilization of the additional reference objects was observed, though these differences were not statistically significant.

The influence of the pre-test instruction content on the result of the six-minute walk test in schoolchildren with congenital heart defects

Background. The 6-minute walk test (6MWT) is a widely used instrument for assessing the patient’s functional status and selecting parameters of physical training. The distance covered in 6 minutes is the main result of 6MWT, however, this indicator is influenced by many factors: age, gender, weight, height of the patient, the methodology of the test. Objective. To assess the influence of various pre-test instructions on the distance value covered during the 6MWT by schoolchildren with congenital heart defects. Material and methods. 67 patients with corrected congenital heart defects and congestive heart failure aged 12.8 (7–16) years were included, 59.5 % were boys. Everyone underwent two 6MWT with different instructions for implementation. Test 1: the patient was given the goal to walk the maximum possible distance in 6 minutes (the “Further” test — FT). Test 2: The patient was instructed to walk as fast as possible in order to cover the maximum possible distance in 6 minutes (the “Faster and Further” test — FFT). The sequence of tests was random. Results. The distance covered in FFT was greater than in FT in 79.2 % of the surveyed, amounting to 505 [439; 570] meters and 580 [507; 648] meters (p &lt; 0.0001) or 69 [57; 79] % and 79 [70; 87] % of the required values (p &lt; 0.0001) respectively for FT and FFT tests. The heart rate measured in the first 10 seconds after physical activity in 89.6 % of patients was higher in FFT — 126 [110–139] BPM, in FT — 104 [92–120] BPM (p &lt; 0.0001) or 60.2 [53.2; 67.5] % and 50.3 [44.5; 56.7] % of the maximum calculated heart rate (220-age). The increase in heart rate was 40 [25; 48] BPM and 15 [10; 28] BPM or 31.1 [20.1; 41.7] % and 12.9 % [8.8; 22.8] of the heart rate reserve, respectively, in the FT and FFT groups, p &lt; 0.0001. Conclusion. The instruction to walk “as fast as possible in order to cover as much distance as possible” increases the distance of the 6MWT by increasing the intensity of physical effort without reducing the safety of the study. This increases the informativeness of the test in assessment the patient’s functional status and the formation of a physical rehabilitation program.

Correlation between internal limiting membrane preservation and sub-epiretinal membrane space during epiretinal membrane surgery.

Internal limiting membrane (ILM) is usually peeled simultaneously with epiretinal membrane (ERM), however, in eyes with glaucoma and ERM, ILM is preserved in order to prevent nerve fiber damage. The aim of this study was to evaluate if a new approach for ERM is effective to keep ILM during surgery. Retrospective consecutive case series. ERM was directly grasped with forceps at the site where the scale of submembrane space imaged in OCT was maximum. After the removal of ERM, ILM was stained with brilliant blue G and the area of remaining ILM was graded with 5 patterns. The relationship between ILM preservation and submembrane space was analyzed with ROC curve. Thirty-three eyes of 33 patients undergoing ERM surgery (14 women, mean age: 69.2 years) were enrolled. There were 3 eyes with stage 1, 11 eyes with stage 2, 18 eyes with stage 3, and 1 eye with stage 4. The mean maximum distance between ERM and ILM was 80.5 ± 36.0μm before surgery. ILM was preserved after initial membrane peeling in 21 of 33 eyes (63.6%). ERM-ILM distance correlated with ILM grading (Spearman rank coefficient: P = 0.03). ROC curve analysis identified cutoff value of ERM-ILM distance for ILM preservation was 66μm[AUC (95% CI):0.7143 (0.5192-0.9093)]. Eyes with larger ERM-ILM distance are likely to show preserved ILM during ERM surgery. ERM-ILM distance appears to be a biomarker of ILM preservation during ERM surgery, which would be useful to minimize neuroretinal damage in eyes with glaucoma and related diseases.

Unveiling the flux tube structure in full QCD

We present lattice Monte Carlo results on the chromoelectric field created by a static quark–antiquark pair in the vacuum of QCD with 2+1 dynamical staggered fermions at physical masses. After isolating the nonperturbative, confining part of the field, we characterize its spatial profile for several values of the physical distances between the sources, ranging from about 0.5 fm up to the onset of string breaking. Moreover, we compare our results with a model of QCD vacuum as disordered chromomagnetic condensate.

Three-Dimensional Digital Documentation for the Conservation of the Prambanan Temple Cluster Using Guided Multi-Sensor Techniques

The Prambanan Temple cluster is a world heritage site that has significant value for humanity, a multiple zone cluster arrangement of highly ornamented towering temples, and a Hindu architectural pattern design. It lies near the Opak Fault, at the foothills of Mount Merapi, on an unstable ground layer, and is surrounded by human activities in Yogyakarta, Indonesia. The site’s vulnerability implies the necessity of 3D digital documentation for its conservation, but its complexity poses difficulties. This work aimed to address this challenge by introducing the utilization of architectural pattern design (APD) to guide multi-sensor line-ups for documentation. First, APDs were established from the literature to derive the associated multiple detail levels; then, multiple sensors and modes of light detection and ranging (Lidar) scanners and photogrammetry were utilized according to their detail requirements and, finally, point cloud data were processed, integrated, assessed, and validated by the proof of the existence of an APD. The internal and external qualities of each sensor result showed the millimeter- to centimeter-range root mean squared error, with the terrestrial laser scanner (TLS) having the best accuracy, followed by aerial close-range and terrestrial-mode photogrammetry and nadiral Lidar and photogrammetry. Two relative cloud distance analyses of every point cloud model to the reference model (TLS) returned the millimeter and centimeter ranges of the mean distance values. Furthermore, visually, every point cloud model from each sensor successfully complemented each other. Therefore, we can conclude that our approach is promising for complex heritage documentation. These results provide a solid foundation for future analyses, particularly in assessing structural vulnerabilities and informing conservation strategies.

Short-term effectiveness of Gamma 3 U-Blade system for osteoporotic intertrochanteric fractures in the elderly

To compare the short-term effectiveness between Gamma 3 intramedullary nails and Gamma 3 U-Blade system in the treatment of osteoporotic intertrochanteric fractures in the elderly. A retrospective analysis was conducted on the clinical data of 124 elderly patients with osteoporotic intertrochanteric fractures, who were admitted between February 2020 and February 2023 and met the selection criteria. The fractures were fixed with Gamma 3 intramedullary nails in 65 patients (control group) and Gamma 3 U-Blade systems in 59 patients (UB group). The differences between the two groups were not significant in age, gender, body mass index, American Society of Anesthesiologists (ASA) classification, bone mineral density, time from injury to operation, fracture classification, and affected side ( P>0.05). The operation time, intraoperative blood loss, hospital stay, and fracture healing time were recorded; the tip-apex distance, fracture reduction quality, and lag screw position were evaluated on X-ray films at immediate after operation; the lag screw sliding distance and change value of neck-shaft angle were measured on X-ray films at last follow-up. Harris hip score at 1 year after operation and the occurrence of internal fixation-related complications were compared between the two groups. The operation time, intraoperative blood loss, and hospital stay in the UB group increased compared to the control group, but the differences were not significant ( P>0.05). All patients in both groups were followed up 12-24 months (mean, 17.1 months). At 12 months after operation, there was no significant difference in the Harris hip score between the two groups ( P<0.05). Radiological examination showed that there was no significant difference between the two groups ( P>0.05) in terms of tip-apex distance, fracture reduction quality, and lag screw position. Fractures healed in both groups, and there was no significant difference in healing time ( P>0.05). At last follow-up, the change value of neck-shaft angle and lag screw sliding distance in the UB group were significantly lower than those in the control group ( P<0.05). During follow-up, no related complications occurred in the UB group, while 6 cases (9.2%) in the control group experienced complications, and the difference in the incidence was significant ( P<0.05). For the osteoporotic intertrochanteric fractures in the elderly, the Gamma 3 U-Blade system fixation can achieve good short-term effectiveness, with better imaging results compared to Gamma 3 intramedullary nails fixation.

Exploring the Gating Mechanism of the Human Copper Transporter, hCtr1, Using EPR Spectroscopy.

Ctr1 is a membrane-spanning homotrimer that facilitates copper uptake in eukaryotic cells with high affinity. While structural details of the transmembrane domain of human Ctr1 have been elucidated using X-ray crystallography and cryo-EM, the transfer mechanisms of copper and the conformational changes that control the gating mechanism remain poorly understood. The role of the extracellular N-terminal domains is particularly unclear due to the absence of a high-resolution structure of the full-length hCtr1 protein and limited biochemical and biophysical characterization of the transporter in solution and in cell. In this study, we employed distance electron paramagnetic resonance to investigate the conformational changes of the extracellular N-terminal domain of full-length hCtr1, both in vitro and in cells, as a function of Cu(I) binding. Our results demonstrate that at specific Cu(I) concentrations, the extracellular chains move closer to the lumen to facilitate copper transfer. Additionally, while at these concentrations the intracellular part is penetrating the lumen, suggesting a ball-and-chain gating mechanism. Moreover, this phenomenon was observed for both reconstituted protein in micelles and in native cell membranes. However, the measured distance values were slightly different, suggesting that the membrane's characteristics and therefore its lipid composition also impact and even regulate the gating mechanism of hCtr1.

Molecular Taxonomy Suggests Presence of Two Distinct Lineages of Blue Sheep (Pseudois nayaur) in Indian Himalayan Region.

Indian Himalayan Region (IHR) supports a plethora of biodiversity with a unique assemblage of many charismatic and endemic species. We assessed the genetic diversity, demographic history, and habitat suitability of blue sheep (Pseudois nayaur) in the IHR through the analysis of the mitochondrial DNA (mtDNA) control region (CR) and Cytochrome b gene, and 14 ecological predictor variables. We observed high genetic divergence and designated them into two genetic lineage groups, i.e., the Himalayan blue sheep (P. n. nayaur) in the western part, and the Chinese blue sheep (P. n. szechuanensis) in the eastern part. They exhibited poor connectivity due to landscape resistance. The genetic distance value suggested substantial genetic differentiation between them. The habitat selection by blue sheep indicated the disparity between the residence preferences in the western and eastern Himalayas. In both the regions, the habitat suitability was mostly influenced by the minimumtemperature of the coldest month. However, in the eastern Himalayas,precipitation seasonalityemerged as a significant variable influencing habitat suitability. These findings provided strong support for the presumption that the habitats preferred by blue sheep in the western Himalayas are dryer, compared with the preferred habitats in the eastern region, which were moister. The identification of two separate lineages of P. nayaur in the IHR has significant conservation implications as it underlines the necessity for a unique management approach for each lineage. In order to preserve genetic integrity, conservation efforts must make sure that each population is maintained and monitored separately, as genetic divergence across the lineages that might indicate reproductive isolation. This study has potential conservation implications as it provides insights on the crucial ecological information of a relatively lesser-known ungulates species of Himalaya essential for effective conservation planning.

Response of Understory Plant Diversity to Edge Effects in Plantation Forests on the Loess Plateau

The majority of the world’s forests are located at landscape edges and are highly fragmented; the plantations on the Loess Plateau are no exception, experiencing pronounced edge effects. However, edge effects are often overlooked in assessments of carbon storage and biodiversity, and the extent and impact of these effects on Loess Plateau plantations remain inadequately understood. The objective of this study is to reveal how edge effects influence biodiversity and species composition and to examine their long-term impacts on ecosystem structure and function. Furthermore, it aims to explore the mechanisms underlying edge effects in plantation systems. Examining these effects is essential for guiding forest management practices and formulating effective biodiversity conservation strategies, thereby providing scientific insights to support the ecological restoration and sustainable management of plantations. In this study, we classified 44 sample plots into four groups according to their distances from the plantation edges to compare and analyze species composition. Additionally, we evaluated the intensity and range of edge effects on stand structure, species diversity, and carbon storage. The Shannon index of understory vegetation was used as the dependent variable, with canopy cover, edge distance, and stand density as independent variables. We used multiple linear regression to examine the effects of these factors on the Shannon index of understory vegetation (shrubs, herbs, and trees). The key findings were as follows: (1) Tree height did not exhibit edge effects across any distance range, while the Shannon index, species richness, and carbon storage showed edge effects within 54 m from the edge. Diameter at breast height (DBH), stand density, and canopy cover exhibited edge effects within 0–83 m from the edge. (2) The significance values for edge distance and canopy cover in the linear regression with the Shannon index were 0.99 and 0.51, respectively, showing no significant correlation. In contrast, stand density had a significant positive effect on the Shannon index (p = 0.03). (3) Notable differences in understory species composition were observed between the outermost and innermost groups of the plantation. Climatic conditions on the Loess Plateau exert a dominant influence on understory plants, altering species composition and abundance. High stand density appeared to moderate the microclimate, contributing to a higher understory Shannon index, but reducing carbon storage. Our findings suggest that the edge effects of plantation forests on the Loess Plateau exert varying degrees of influence on different indicators. Management decisions should be guided by the specific silvicultural objectives, whether the manager’s goals are to optimize biomass accumulation, enhance species recovery, or achieve a balance between these two goals.

Crown Gall Induced by a Natural Isolate of Brucella (Ochrobactrum) pseudogrignonense Containing a Tumor-Inducing Plasmid.

Crown gall disease in plants is caused by "Agrobacteria", bacteria belonging to the Rhizobiaceae family, which carry a tumor-inducing (Ti) plasmid. Unexpectedly, we found evidence that a natural isolate from a rose crown gall, called NBC51/LBA8980, was a bacterium that did not belong to the Rhizobiaceae family. Whole-genome sequencing revealed that this bacterium contained three large DNA circles with rRNA and tRNA genes, representing one chromosome and two chromids, respectively, and two megaplasmids, including a Ti plasmid. Average nucleotide identity (ANIb, ANIm) and genome-to-genome distance (GGDC) values above the thresholds of 96% and 70%, respectively, showed that NBC51/LBA8980 belonged to the species Brucella (Ochrobactrum) pseudogrignonense. Its Ti plasmid was almost identical to certain succinamopine Ti plasmids previously identified in Agrobacterium strains, suggesting that this Ti plasmid may have been recently acquired by NBC51/LBA8980 in the tumor environment.

Biomechanical Analysis and Solution Suggestions of Screw Replacement Scenarios in Femoral Neck Fracture Surgeries: Finite Element Method.

Despite several surgical options, there has yet to be a consensus on the best treatment for femoral neck fracture (FNF) due to higher complication rates compared to other bone fractures. This study aims to examine the possible consequences and solution suggestions of changing screws during surgery for various reasons in FNF surgical treatment from a biomechanical perspective. FNF and treatment materials were analyzed biomechanically using a package program based on the finite element method (FEM). This study created a solid model with images of femur bone tomography. Dynamic hip screws (DHS), cannulated screws (CCS), and medial buttress plates (MBP) were obtained by making three-dimensional designs. The required elements for the models were assigned, and the material properties of the elements were defined. The solutions were obtained as crack distance and deformation results after defining the boundary conditions and applying the necessary loading. The strain and crack distance values created by six models on the fracture line under different parameters were obtained, and the numerical results were evaluated. The DHS and CCS models produced the highest crack distance and deformation values when all screws were loose. The lowest values were obtained in the intact-85 model when all CCS were tight. When the results are evaluated, it is seen that the MBP has a decreasing effect on the results. Mechanical evaluation of six different options used in femoral neck fractures was performed. 85 mm CCS applied to our standard model gave the best results, while the use of 80 mm CCS in the same model showed promising results compared to other models. It is understood that CCS have the best stability even in loosening models with the medial support plate. Different models are from intact-85 mm DHS+1CS+MBP to DHS+1CS, which was worked with LSR+USR-2, according to decreasing stability. This study offers various biomechanical solutions to possible intraoperative problems in FNF treatment. The following results were obtained from the study data. When the CCS needs to be lengthened or replaced, it is appropriate to use the CCS with the MBP. A single anti-rotation screw is sufficient for lag screw extensions of the DHS plate, and the MBP may be a savior procedure in surgery.

Significance of the Lesion-Pleura Relationship in Differentiating Peripheral Inflammatory Lesions and Lung Cancers.

To determine the significance of lesion-pleura relationship in differentiating peripheral inflammatory lesions (PILs) and peripheral lung cancers (PLCs). From January 2017 to April 2022, a total of 743 patients with 501 PLCs and 292 PILs (≥1.5 cm) were retrospectively enrolled. The patients' clinical characteristics and CT features of lesions in these two groups were analyzed and compared, and the impact of the lesion-pleura relationship (broad or narrow basement and distance between lesion and pleura) on differentiation was specifically assessed. Lesions attached to pleura were more frequent in PILs (188, 64.4%) than in PLCs (244, 48.7%) (P < 0.001), and those with broad basement-to-pleura were also more common in PILs (133, 70.7%) than in PLCs (47, 19.3%) (P < 0.001). Among the 296 lesions with a lesion-pleura distance ≤16 mm, the optimal cutoff value of distance was ≤8.9 mm (area under curve [AUC], 0.733; sensitivity: 0.770; specificity: 0.623; P < 0.001) for predicting PLCs. Regarding the 728 lesions attached to pleura or with a lesion-pleura distance ≤16 mm, the AUC of the model based on the clinical and CT features for predicting PLCs significantly increased from 0.812 to 0.879 after including lesion-pleura relationship (narrow basement or lesion-pleura distance ≤ 8.9 mm) (P < 0.001). Additionally, the lesion-pleura relationship was one of independent indicators for differentiation (odds ratio, 9.433; P < 0.001). When differentiating peripheral lesions (≥1.5 cm), it is crucial to consider the basement-to-pleura and lesion-pleura distance besides patients' clinical characteristics, laboratory parameters and morphological features.

Genetic diversity and population structure of Oncomelania hupensis in Sichuan Province, China: implications for schistosomiasis control.

Schistosomiasis, caused by the infection with Schistosoma japonicum, remains a significant public health concern in China. As the sole intermediate host of S. japonicum, the breeding and spread of Oncomelania hupensis contribute significantly to the potential risk of disease occurrence and transmission. Exploring the population genetics of the snail vector is conducive to better understanding its distribution and dispersal patterns, and provides more data for future snail surveillance and control from a molecular perspective. The genetic diversity and population structure of O. hupensis in Sichuan Province were evaluated based on sequencing of mitochondrial cytochrome c oxidase subunit 1. A total of 215 snail isolates were collected from 30 counties, identifying 80 haplotypes with high nucleotide diversity (0.05871±0.00160) and haplotype diversity (0.979±0.003). Phylogenetic analysis and haplotype network construction identified five distinct clades. Notably, clade 1 was confined within the Panxi region, while clade 5 exhibited a widespread distribution across the studied areas, distinct from the other four clades, but showing a close genetic relationship to individuals from Yunnan. Spatial differentiation was revealed by significant pairwise genetic distance values detected in 313 out of 435 population pairs, ranging from 0.07632 to 1.00000. Analysis of molecular variance (AMOVA) showed that the majority of variance occurred among populations, but significant differences were also observed among landscape groups. AMOVA also provided support for clade separation by exhibiting significant genetic differences among the clades, which explained 78.23% of the overall variation. Geographical distance and precipitation were found to display a significant correlation with the genetic differentiation pattern of O. hupensis in both Mantel and partial Mantel tests. Temporal stability was observed over sampling intervals of 7years, particularly among snail populations inhabiting the Panxi area, despite prolonged molluscicide treatment. This study provides updated insights into the genetic diversity and population structure of O. hupensis in Sichuan Province, which contribute to a better understanding of the challenges faced in snail control. In light of the findings, the integration of molecular insights into snail monitoring and control, and the reinforcement of collaborative efforts in neighboring regions, in addition to long-distance monitoring, are suggested.

Reconstruction of Random Structures Based on Generative Adversarial Networks: Statistical Variability of Mechanical and Morphological Properties

Generative adversarial neural networks with a variational autoencoder (VAE-GANs) are actively used in the field of materials design. The synthesis of random structures with nonrepeated geometry and predetermined mechanical properties is important for solving various practical problems. Geometric parameters of such artificially generated random structures can vary within certain limits compared to the training dataset, causing unpredicted fluctuations in their resulting mechanical response. This study investigates the statistical variability of mechanical and morphological characteristics of random 3D models reconstructed from 2D images using a VAE-GAN neural network. A combined multitool method employing different mathematical and statistical instruments for comparison of the reconstructed models with their corresponding originals is proposed. It includes the analysis of statistical distributions of elastic properties, morphometric parameters, and stress values. The neural network was trained on two datasets, containing models created based on Gaussian random fields. Statistical fluctuations of the mechanical and morphological parameters of the reconstructed models are analyzed. The deviation of the effective elastic modulus of the reconstructed models from that of the original ones was less than 5.7% on average. The difference between the median values of ligament thickness and distance between ligaments ranged from 3.6 to 6.5% and 2.6 to 5.2%, respectively. The median value of the surface area of the reconstructed geometries was 4.6–8.1% higher compared to the original models. It is thus shown that mechanical properties of the NN-generated structures retain the statistical variability of the corresponding originals, while the variability of the morphology is highly affected by the training set and does not depend on the configuration of the input 2D image.

AqUavplant Dataset: A High-Resolution Aquatic Plant Classification and Segmentation Image Dataset Using UAV

Aquatic vegetation species are declining gradually, posing a threat to the stability of aquatic ecosystems. The decline can be controlled with proper monitoring and mapping of the species for effective conservation and management. The Unmanned Ariel Vehicle (UAV) aka Drone can be deployed to comprehensively capture large area of water bodies for effective mapping and monitoring. This study developed the AqUavplant dataset consisting of 197 high resolution (3840px × 2160px, 4K) images of 31 aquatic plant species collected from nine different sites in Bangladesh. The DJI Mavic 3 Pro triple-camera professional drone is used with a ground sampling distance (GSD) value of 0.04-0.05 cm/px for optimal image collection without losing detail. The dataset is complemented with binary and multiclass semantic segmentation mask to facilitate ML based model development for automatic plant mapping. The dataset can be used to detect the diversity of indigenous and invasive species, monitor plant growth and diseases, measure the growth ratio to preserve biodiversity, and prevent extinction.

Early player transition in elite youth and first team soccer: The predictive role of sprint distance and high-intensity acceleration and deceleration attributes

Physical performance is an important determinant of elite youth soccer player development and can influence successful transition through the professional phase of the talent development pathway. In response to previous research highlighting key stakeholders’ perceptions that successful transitions within the club pathway are influenced by sprinting capacity and explosive power; this study objectively quantified the predictive value of sprint distance and high intensity acceleration and deceleration efforts on the early transition of elite, professional youth soccer players from U18 to U21, and U21 to first team squads of a Scottish Premier League club. Early transition was defined as a player progressing to the next age group (i.e., U18 to U21) prior to reaching the chronological age limits of his current squad. Retrospective physical performance data of thirty-seven players from training and competitive matches across two seasons were analysed. Results suggest that early transition is less likely for players progressing from the U21 to the first team relative to players progressing from U18 to U21. Relative sprint distance resulted in a 52% probability of early transition (OR = 0.52) with relative aggregated high intensity acceleration and deceleration efforts reflecting an increased probability of early transition (OR = 1.70) for elite youth soccer players within the club. This novel study provides a unique insight to the complexities and context-specific nature of youth soccer player development and transition. This paper challenges the subjective perceptions of key stakeholders using objective physical data of youth players who have transitioned to advanced squads.