Vaccine Attitudes Research Articles

Psychometric properties of the motors of COVID-19 vaccination acceptance scale in New Zealand: Insights from confirmatory factor analysis

High vaccination coverage plays an essential role in curbing epidemics and pandemics, making it important to have a country-specific valid and standardised instruments for assessing vaccination attitudes. This study aimed to assess the psychometric properties of the Motors of COVID-19 Vaccination Acceptance Scale (MoVac-COVID19S) in New Zealand. A total of 413 participants completed an online survey in June and July 2022, which included the MoVac-COVID19S questions, demographic factors, and a single-item measure of COVID-19 vaccination willingness. Confirmatory Factor Analysis (CFA) was used to examine the factor structures of the scale. Results indicated that the one-factor structure of the 9-item version best fitted the data compared to the one and four factor structures of the 12-item version, which showed acceptable fit indices after model modifications. All estimated fit indices were acceptable: CFI, GFI, and TLI > 0.95, RMSEA and SRMR < 0.08. The full scales of the MoVac-COVID19S demonstrated excellent reliability for both the 12-item (α = 0.91; ω = 0.91) and the 9-item (α = 0.94; ω = 0.95) versions. The bifactor model indicated a strong general factor, explaining 60–90% of the Explained Common Variance (ECV) for most items, surpassing specific factors. The MoVac-COVID19S is a reliable and valid scale to measure COVID-19 vaccination attitudes. The 9-item version appeared as the best choice for a unidimensional assessment. Future vaccination programmes can benefit from an adapted version of the MoVac-COVID19S to assess public attitudes towards new vaccines. Further psychometric assessment, including Rasch analysis, is recommended to strengthen the reliability and validity of the MoVac-COVID19S.

Exploring Hepatitis B Vaccination Compliance, Knowledge, and Attitudes among Preclinical Medical Students: A Study at Kampala International University Western Campus

This study delves into the hepatitis B vaccination landscape among preclinical medical students at Kampala International University Western Campus, aiming to illuminate compliance, knowledge, and attitudes toward vaccination. Employing a robust cross-sectional study design and quantitative data collection methods, 296 participants were randomly selected and surveyed. Results unveiled a concerning low compliance rate of 46.28%, indicative of potential gaps in vaccination coverage within this high-risk cohort. Nonetheless, a notable 69.81% expressed willingness to receive the vaccine, hinting at a latent potential for heightened compliance. While 66.22% of students demonstrated adequate knowledge, a significant 33.78% exhibited knowledge gaps, underscoring the need for targeted educational initiatives. Despite apprehensions regarding side effects and cost, attitudes toward vaccination remained largely positive, with 90.54% affirming its safety and effectiveness. These findings spotlight the imperative for tailored interventions to bolster vaccination rates, rectify knowledge deficits, and mitigate barriers to compliance among preclinical medical students. Keywords: Hepatitis B virus infection; Vaccination compliance; vaccinated students; Hepatitis B vaccine; and medical students.

Motivation for COVID-19 Vaccination: Applying a Self-Determination Theory Perspective to a Global Health Crisis

Examining the spectrum of vaccine attitudes within the general public, spanning from hesitancy to confidence, is pivotal in addressing the challenges posed by the COVID-19 pandemic. Despite widespread campaigns advocating for vaccine uptake, a proportion of the population harbour reservations about the safety and efficacy of vaccines. This study seeks to explore the determinants of vaccine attitudes in Canada, leveraging key concepts from the well-established Self-Determination Theory (SDT), including basic psychological needs and the quality of an individual’s motivation. During a crucial juncture in the COVID-19 pandemic (December 2021), 292 participants were recruited and completed an online survey assessing levels of satisfaction/frustration of basic psychological needs (sense of autonomy, relatedness, and competence), vaccine attitudes (confidence and hesitancy), and motivation towards vaccination (controlled and autonomous). Two mediation models were employed to examine whether autonomous-controlled motivation mediated the relationship between need satisfaction-frustration and vaccine attitudes. Model 1 revealed a full mediating effect, indicating that need satisfaction influenced vaccine confidence only through autonomous motivation (ab1 = 0.09, SE = 0.04, z = 2.19, 95 % CI [0.01, 0.18]). Meanwhile, Model 2 demonstrated that need frustration was associated with vaccine hesitancy partially through controlled motivation (ab2 = 0.05, SE = 0.02, z = 2.54, 95 % CI [0.02, 0.10]). These findings underscore the applicability of SDT in investigating the motivational mechanisms that shape vaccine attitudes. Recognizing psychosocial factors, including the balance of basic needs and quality of motivations, may be integral to informing effective public health strategies.

Attitudes Toward COVID-19 Vaccines Among Pregnant and Recently Pregnant Individuals

Pregnant people and infants are at high risk of severe COVID-19 outcomes. Understanding changes in attitudes toward COVID-19 vaccines among pregnant and recently pregnant people is important for public health messaging. To assess attitudinal trends regarding COVID-19 vaccines by (1) vaccination status and (2) race, ethnicity, and language among samples of pregnant and recently pregnant Vaccine Safety Datalink (VSD) members from 2021 to 2023. This cross-sectional surveye study included pregnant or recently pregnant members of the VSD, a collaboration of 13 health care systems and the US Centers for Disease Control and Prevention. Unvaccinated, non-Hispanic Black, and Spanish-speaking members were oversampled. Wave 1 took place from October 2021 to February 2022, and wave 2 took place from November 2022 to February 2023. Data were analyzed from May 2022 to September 2023. Self-reported or electronic health record (EHR)-derived race, ethnicity, and preferred language. Self-reported vaccination status and attitudes toward monovalent (wave 1) or bivalent Omicron booster (wave 2) COVID-19 vaccines. Sample- and response-weighted analyses assessed attitudes by vaccination status and 3 race, ethnicity, and language groupings of interest. There were 1227 respondents; all identified as female, the mean (SD) age was 31.7 (5.6) years, 356 (29.0%) identified as Black race, 555 (45.2%) identified as Hispanic ethnicity, and 445 (36.3%) preferred the Spanish language. Response rates were 43.5% for wave 1 (652 of 1500 individuals sampled) and 39.5% for wave 2 (575 of 1456 individuals sampled). Respondents were more likely than nonrespondents to be White, non-Hispanic, and vaccinated per EHR. Overall, 76.8% (95% CI, 71.5%-82.2%) reported 1 or more COVID-19 vaccinations; Spanish-speaking Hispanic respondents had the highest weighted proportion of respondents with 1 or more vaccination. Weighted estimates of somewhat or strongly agreeing that COVID-19 vaccines are safe decreased from wave 1 to 2 for respondents who reported 1 or more vaccinations (76% vs 50%; χ21 = 7.8; P < .001), non-Hispanic White respondents (72% vs 43%; χ21 = 5.4; P = .02), and Spanish-speaking Hispanic respondents (76% vs 53%; χ21 = 22.8; P = .002). Decreasing confidence in COVID-19 vaccine safety in a large, diverse pregnant and recently pregnant insured population is a public health concern.

COVID-19 Phobia in Pregnant Women and its Effect on Vaccination Attitude

COVID-19 Phobia in Pregnant Women and its Effect on Vaccination Attitude

COVID-19 Vaccine Knowledge, Attitude, and Acceptance in Students of Tertiary Institutions in Central Nigeria

INTRODUCTION/BACKGROUND: On March 11, 2020, the World Health Organization declared the COVID-19 outbreak a global pandemic. Nigeria, among African nations, has borne the highest burden of COVID-19 reporting 163,498 cases and 2,058 fatalities. Institutions of higher learning possess certain characteristics that can increase the risk of COVID-19 transmission within their campuses. These features include a sizable student population, high population density, and frequent student interactions. As a result, it is imperative to implement protective measures to mitigate the virus&amp;rsquo;s spread on campus. &#x0D; &#x0D; AIM/OBJECTIVE: This research aimed to explore the connection between the knowledge, attitudes, and acceptance of COVID-19 vaccines among students in tertiary institutions located in Central Nigeria. &#x0D; &#x0D; METHODOLOGY: An anonymous online survey was conducted among Nigerian students, gathering information related to their demographics, as well as assessing their knowledge, attitudes, and willingness to accept vaccines in the post-COVID-19 era. The collected data were subjected to analysis through descriptive and inferential statistics.&#x0D; &#x0D; RESULTS: Out of the 400 participants included in the survey, 140 (35.0%) reported having already received a COVID-19 vaccine, while 144 (36.0%) expressed an intention to be vaccinated. The analysis indicated that there is a positive yet very weak correlation between attitudes towards COVID-19 vaccination and the intention to get vaccinated (r = &amp;minus;0.023, N = 365, p &amp;lt; 0.01). Conversely, knowledge regarding COVID-19 vaccines demonstrated a significant positive correlation with the intent to be vaccinated (r = 0.222, N = 367, p &amp;lt; 0.01). &#x0D; &#x0D; CONCLUSION: In conclusion, this study underscores the importance of students&amp;rsquo; knowledge and attitudes regarding vaccines in shaping their acceptance of COVID-19 vaccines. The results emphasize the critical necessity of providing comprehensive information on COVID-19 vaccines to address concerns related to unforeseen side effects, mitigate general mistrust in vaccine benefits, and alleviate apprehensions about the profitability of pharmaceutical companies.

The Uptake of Pneumococcal and Seasonal Influenza Vaccinations Based on Perceptions and Attitudes Toward the COVID-19 Vaccine Among Patients With Diabetes.

Objective In this study, we aimed to assess the rates of pneumococcal and seasonal influenza vaccinations among elderly and nonelderly diabetes patients andexamine their perceptions and attitudes toward the coronavirus disease 2019 (COVID-19) vaccine. Methods A single-center study was conducted among patients with diabetes, employing a structured survey encompassing sociodemographic data, vaccination records, and the COVID-19 vaccine perception and attitude scale. Results Among the 280 diabetes patients in our study, the vaccination rates for COVID-19, seasonal influenza, and pneumococcal vaccines were 96.1%, 16.8%, and 17.5%, respectively. A higher cumulative dosage of the COVID-19 vaccine was associated with older age (r = 0.463; p<0.001), increased safety score (r = 0.479; p<0.001), and lower conspiracy theory score (r = -0.336; p<0.001). Participants who had received COVID-19 and influenza vaccines were observed to have significantly higher safety scores related to COVID-19 vaccines (p<0.001; d = 2.381and p = 0.008; d = 0.525, respectively).Notably, vaccination rates for influenza and pneumococcus were significantly different between nonelderly and elderly patients (8.7% vs. 29.6%; p<0.001 and 13.4% vs. 24.1%; p = 0.022). Elderly patients with diabetes were 3.3 times more likely to receive the influenza vaccine than nonelderly participants [odds ratio (OR) = 3.319; 95% confidence interval (CI) = 1.592 - 6.920; p = 0.001] and had a higher safety score related to COVID-19 vaccines (OR= 1.076; 95% CI = 1.011 - 1.146; p = 0.021). Conclusions Both influenza and pneumococcal vaccination rates were below the desired targets in this study. The vaccination rates among the nonelderly diabetes population suggest that this group may be more likely to neglect to receive vaccination compared to the elderly diabetes population. The association between vaccination rates and post-pandemic safety perceptions highlights the critical need to implement public health strategies specifically designed to address and improve safety-related information dissemination.

Why Do People Believe in Vaccine Misinformation? The Roles of Perceived Familiarity and Evidence Type

ABSTRACT The proliferation of health misinformation poses a significant threat to public health, making it increasingly important to understand why misinformation is accepted. The illusory truth effect, which refers to the increased believability of a message due to repeated exposure, has been widely studied. However, there is limited research on this effect in the context of COVID-19 vaccine misinformation. This paper aims to examine the role of perceived familiarity with COVID-19 vaccine misinformation on various message perceptions, including perceived accuracy, agreement, perceived message effectiveness, and determinants of vaccination, including vaccine attitude and vaccination intention. Furthermore, it explores the impact of misinformation evidence (statistical vs. narrative) on the magnitude of the effects of perceived familiarity. To investigate these factors, a between-subjects experimental study was conducted, employing a 2 (Familiarity: strong vs. weak) × 3 (Evidence type: statistical, narrative, and both evidence) + 1 (Control: a message about drinking water) design. The results revealed that perceived familiarity with COVID-19 vaccine misinformation significantly predicted perceived accuracy, which was found to be negatively correlated with vaccine attitudes and vaccination intentions. Moreover, statistical evidence presented in misinformation was perceived as more persuasive in perceived message effectiveness, compared to narrative and mixed evidence. Interestingly, the effects of perceived familiarity were not contingent on the type of evidence used in COVID-19 vaccine misinformation. These findings emphasize the importance of avoiding the repetition of misinformation, reducing the processing fluency associated with misinformation correction, and educating individuals on how to critically evaluate statistical evidence when encountering (mis)information.

Differences in social media use by COVID-19 vaccination status

The near-ubiquitous use of social media in the United States (U.S.) highlights the utility of social media for encouraging vaccination. Vaccination campaigns have used social media to reach audiences, yet research linking the use of specific social media platforms and vaccination uptake is nascent. This descriptive study assesses differences in social media use by COVID-19 vaccination status among adults overall and those who reported baseline vaccine hesitancy. We used data from a nationally representative longitudinal survey of U.S. adults administered between January 2021–August 2022 (n = 2,908). Results indicated a positive association between frequent Instagram and/or Twitter use and vaccination status (p <.05). Among baseline vaccine hesitant adults, results indicated a positive association between frequent TikTok, Instagram, and/or Twitter use and vaccination status (p <.05). Findings have implications for research that examines the content of social media platforms and their environment on vaccine attitudes and uptake.

Heritage and hesitancy: how preference for traditional Chinese medicine influences vaccine attitudes.

Vaccine hesitancy, amplified by the COVID-19 pandemic, is a pressing public health challenge. This study investigates the association between Traditional Chinese Medicine (TCM) preference and COVID-19 vaccine hesitancy within China. The study uses data from the 2021 Chinese General Social Survey (CGSS) (N = 2,690). Logistic regressions and Karlson-Holm-Breen (KHB) method are employed to analyzed the relationship between TCM preference and vaccine hesitancy. The study reaffirms prior findings by revealing a robust and stable association between TCM preference and vaccine hesitancy, which remains unaffected by socioeconomic and demographic confounders, as well as institutional trust dynamics of healthcare system. Contrary to expectations, TCM enthusiasts do not exhibit vaccine hesitancy based on divergent epistemological views concerning vaccine risks and immunity acquisition compared to biomedicine. This research enriches understandings of the intricate relations between healthcare paradigms and vaccine attitudes, inviting further inquiry into the role of CAM in shaping vaccination behaviors across different cultures and contexts. The insights bear significant public health implications for enhancing vaccine acceptance and coverage, particularly among populations where CAM practices wield substantial influence.

COVID-19 vaccination and potential predictors for vaccination among students in Bulgarian medical universities

University students, especially those in healthcare sciences, are of particular importance in COVID-19 vaccine views since their future careers will allow them to educate citizens regarding vaccination. The study examined COVID-19 immunisation coverage, behaviours, and attitudes towards COVID-19 vaccines among students in Bulgarian medical universities. A prospective cross-sectional study was undertaken in September 2021- January 2022. Demographics, university programme, year of study, general vaccine attitudes and behaviour, and personal experience with COVID-19 and vaccines were collected. The chi-square test was used to test for associations and binominal logistic regression to identify possible predictors for vaccination. A total of 3050 students with a median age of 22 years, predominantly female participated. Three-quarters of the students (73.5%) have been vaccinated against COVID-19. An association was found between COVID-19 vaccination and influenza vaccination in the previous season (χ2 = 67.15, p < 0.001) as well as the intention to receive the flu vaccine in the current season (χ2 = 142.83, p < 0.001). Vaccine hesitation mainly stemmed from fear of side effects and safety concerns, but non-vaccinated students voiced them more often. Respondents who were less likely to be vaccinated considered themselves to have: (a) limited access to sufficient information to allow them to make an informed decision to vaccinate against COVID-19; (b) lack of public awareness and education campaigns about COVID-19 vaccines; (c) insufficient information about COVID-19 vaccines during university education that would allow them to make an informed decision to vaccinate; and (d) had a positive COVID-19 diagnosis. Informational initiatives that emphasise vaccine safety will boost COVID-19 immunisation coverage.

Estimating COVID-19 vaccine acceptance in pregnant and lactating women: a cross-sectional study in Lebanon.

The COVID-19 pandemic highlights vaccination's critical role in reducing morbidity and mortality, depending on public attitude. This study aims to identify the estimates of COVID-19 vaccine acceptance in pregnant and lactating women, as well as associated potential factors. A cross-sectional study was conducted between August and September 2021, through an online survey and with a paper survey distributed in gynecology and pediatric clinics. Pregnant and breastfeeding women aged 18 years and above were recruited. The attitude scale was created specifically for evaluating attitudes towards the COVID-19 vaccine. In total, 207 women participated, with 132 breastfeeding, 74 pregnant and 1 experiencing both conditions. Of these, one hundred and twenty women (58%) considered themselves at risk for COVID-19 infection. In addition, 51.7% (n = 107) of women expressed the intent to receive the vaccine once available. A multivariable linear regression was conducted taking the COVID-19 vaccination attitude scale as a dependent variable. The results revealed an R-squared value of 0.558, indicating that approximately 55.8% of the variance in the attitude scale was accounted for by the included predictors. The results showed that preventive measures (ß=2.25, 95% Confidence Interval (CI) [1.02; 3.48], p < 0.001), preference for vaccines made in Europe and America (ß=1.23; 95% CI [0.69-1.77], p < 0.001), protect yourself for getting sick (ß=4.22, 95% Confidence Interval (CI) [2.83; 5.61], p < 0.001) and belief in the importance of vaccination for themselves and their baby (ß=3.49; 95% CI [2.01; 4.98], p < 0.001) were associated with a positive attitude towards vaccination. Conversely, experiencing a previous bad reaction to a vaccine (ß= -1.35; 95% CI [0.85-1.85], p < 0.001) and concerns regarding COVID-19 vaccine safety (ß= -4.09; 95% CI [-5.98; -2.21], p < 0.001) were associated with a negative attitude towards vaccination. Our findings reveal that COVID-19 vaccine acceptability among pregnant and breastfeeding women, amidst the pandemic was insufficient to meet community immunity. The identified reasons for vaccine reluctance, notably concerns about safety for both personal health and the health of their pregnancy or newborns, along with insufficient information about the vaccine, underscore the pressing need to address these factors to improve immunization rates.

Cross-sectional study on intention to be vaccinated against Coronavirus Disease 2019 (COVID-19) in Benin and Senegal: A structural equation modeling (SEM).

Vaccination is considered one of the solutions to the Coronavirus Disease 2019 (COVID-19) pandemic. However, a small proportion of the population were fully vaccinated in Benin (20.9%) and Senegal (7.6%) by December 2022. This study explores the determinants of intent to vaccinate. This was a cross-sectional, descriptive, and analytical study of 865 Beninese and 813 Senegalese aged 18 years and older. Marginal quota sampling by age, gender and region was adopted. Data collection, using a survey instrument based on the Random Digit Dialing method, was conducted from December 24, 2020, to January 16, 2021, in Senegal and from March 29 to May 14, 2021, in Benin. The questionnaire used the Theory of Planned Behavior and the Health Belief Model. The influence of factors was assessed using a structural equation model based on a diagonally weighted least squares estimator to account for ordered categorical data (Likert scales). In Benin and Senegal, the intention to vaccinate against COVID-19 is influenced by distinct factors. In Benin, social influence (β = 0.42, p = 0.003) and perception of vaccine safety (β = -0.53, p<0.001) play pivotal roles, suggesting those socially influenced have a higher vaccination intention. In Senegal, vaccination intentions are primarily driven by positive attitudes towards the vaccine (β = 0.65, p = 0.013) and social influence (β = 0.25, p = 0.048). This underscores the importance of individual beliefs, personal perceptions, and supportive social contexts in decision-making. Notably, positive vaccination attitudes and perceptions in both countries are strongly tied to increased social influence. While nuances exist between Benin and Senegal regarding factors influencing COVID-19 vaccination intentions, both nations underscore the pivotal roles of social influence and individual vaccination perceptions. Emphasizing trust in vaccine safety and promoting positive attitudes through effective communication are crucial for enhancing vaccination uptake in these West African countries.

Disparities in COVID-19 vaccine uptake, attitudes, and experiences between food system and non-food system essential workers.

The COVID-19 pandemic has disproportionately affected the health of food system (FS) essential workers compared with other essential and non-essential workers. Even greater disparity exists for workers in certain FS work settings and for certain FS worker subpopulations. We analyzed essential worker respondents (n = 151,789) in May-November 2021 data from the National Immunization Survey Adult COVID Module (NIS-ACM) to assess and characterize COVID-19 vaccination uptake (≥1 dose) and intent (reachable, reluctant), attitudes about COVID-19 and the vaccine, and experiences and difficulties getting the vaccine. We compared rates, overall and by certain characteristics, between workers of the same group, and between FS (n = 17,414) and non-food system (NFS) worker groups (n = 134,375), to determine if differences exist. FS worker groups were classified as "agriculture, forestry, fishing, or hunting" (AFFH; n = 2,730); "food manufacturing facility" (FMF; n = 3,495); and "food and beverage store" (FBS; n = 11,189). Compared with NFS workers, significantly lower percentages of FS workers reported ≥1 dose of COVID-19 vaccine or vaccine requirements at work or school, but overall vaccine experiences and difficulties among vaccinated FS workers were statistically similar to NFS workers. When we examined intent regarding COVID-19 vaccination among unvaccinated FS workers compared with NFS counterparts, we found a higher percentage of FMF and FBS workers were reachable whereas a higher percentage of AFFH workers were reluctant about vaccination, with differences by sociodemographic characteristics. Overall, results showed differences in uptake, intent, and attitudes between worker groups and by some sociodemographic characteristics. The findings reflect the diversity of FS workers and underscore the importance of collecting occupational data to assess health inequalities and of tailoring efforts to worker groups to improve confidence and uptake of vaccinations for infectious diseases such as COVID-19. The findings can inform future research, adult infectious disease interventions, and emergency management planning.

Exploring the Impact of Socio-Demographic, Health, and Political Factors on COVID-19 Vaccination Attitudes

This study examines the influence of socio-demographic, health, and political factors on attitudes towards COVID-19 vaccination during 2021-2022. Utilizing data from the General Social Survey (GSS), the research explores the relationships between COVID-19 vaccination status and variables such as confidence in medicine, political views, general health condition, income, education level, and marital status. The analysis employs logistic regression models and Chi-Square tests to assess these relationships. Key findings indicate that higher income and education levels, as well as more liberal political views, are positively associated with vaccination uptake. In contrast, marital status presents a more complex picture, suggesting further exploration is needed. The study highlights the multifaceted nature of vaccination decisions and underscores the importance of tailored public health strategies that address the specific needs and concerns of different demographic groups. The research also acknowledges challenges and limitations, including issues related to causality, confounding factors, data quality, generalizability, response bias, and multicollinearity. Overall, the study contributes valuable insights for policymakers and public health practitioners aiming to enhance vaccination campaigns and policies.

Pandemic antecedents – Exploring predictivity and relationships between COVID-19 vaccine uptake and influenza, shingles, and HPV vaccination

BackgroundA wealth of extant research focuses on identifying barriers to, and predictors of, COVID-19 vaccination. In addition to treating COVID-19 vaccination and related experiences as antecedents, this study analyzes the relationships between COVID-19 vaccination experiences and intent to receive the flu, shingles, and HPV vaccines. MethodAnalyses were performed on the responses from U.S. survey panel of 1,024 participants (n = 1,024), 530 (51.8 %) who received at least a dose of the COVID-19 vaccine and 494 (48.2 %) who had not. Descriptive and inferential statistics identify participant demographic characteristics, prior vaccination behavior, vaccination intentions, risk behavior assessment, vaccination attitudes and beliefs, and the predictivity of COVID-19 vaccination, when treated as an antecedent. ResultsReceiving a first dose of the COVID-19 vaccine interacted with receiving a past influenza vaccine, predicting the future intention to receive a COVID-19 vaccine or booster. Vaccine hesitancy in parents is significantly related to vaccination behaviors for themselves and their children. Analyses also showed differences between the vaccinated group (VG) and the unvaccinated group (UVG) on hesitancy, beliefs, and attitudes toward the COVID-19 vaccine. ConclusionExperience with COVID-19 vaccination and the relationship of those experiences with other vaccinations provide useful insight on leveraging vaccine uptake. Healthcare professionals should improve the COVID-19 vaccination experience and use vaccination appointments to promote other vaccinations. Research should continue to compare vaccination experiences and how they may persuade or dissuade vaccination intent for other vaccinations.

Pneumococcal vaccine uptake among high-risk adults and children in Italy: results from the OBVIOUS project survey

BackgroundStreptococcus pneumoniae infections, including Invasive Pneumococcal Diseases (IPDs), pose a substantial public health challenge, causing significant morbidity and mortality, especially among children and older adults. Vaccination campaigns have played a vital role in reducing pneumococcal-related deaths. However, obstacles related to accessibility and awareness might impede optimal vaccine adoption. This study aims to provide comprehensive data on pneumococcal vaccine coverage and attitudes within at-risk groups in Italy, with the goal of informing public health strategies and addressing vaccination barriers.MethodsBetween April 11 and May 29, 2022, a questionnaire investigating vaccine uptake and attitudes toward several vaccinations was administered to 10,000 Italian adults, chosen through population-based sampling. Respondents who were targets of the campaign according to the 2017–2019 National Vaccination Plan, accessed questions regarding pneumococcal vaccination. Data on uptake, awareness of having the right to free vaccination, opinion on vaccine safety, concern with pneumococcal disease, and ease of access to vaccination services were summarized and presented based on statistical regions. Multinomial logistic regression analysis was used to explore factors influencing vaccine uptake.ResultsOut of 2357 eligible adult respondents (42.6% women; mean age: 58.1 ± 15.7), 39.5% received pneumococcal vaccination. Uptake differed among at-risk groups: respondents aged ≥65 (33.7%), with lung disease (48.4%), cardiovascular disease (46.6%), and diabetes (53.7%). Predictors of not being vaccinated and unwilling to included female gender, residing in rural areas, lower education, low concern about pneumococcal disease, vaccine safety concerns, and associations with vaccine-opposed acquaintances. Health access issues predicted willingness to be vaccinated despite non-vaccination. Pneumopathy, heart disease, diabetes, and living in Northeastern or Central Italy were linked to higher uptake. Among the 1064 parents of eligible children, uptake was 79.1%. Parental unawareness of children’s free vaccination eligibility was a predictor of non-vaccination. Vaccine safety concerns correlated with reluctance to vaccinate children, while perceived healthcare access challenges were associated with wanting but not having received vaccination.ConclusionsPneumococcal vaccination uptake within prioritized groups and children in Italy remains inadequate. Scarce awareness of vaccine availability and obstacles in accessing vaccinations emerge as principal barriers influencing this scenario.

Will you get vaccinated? Trade‐offs between purity, liberty and care predict attitudes towards Covid‐19 vaccination

AbstractHow do tensions between moral values predict how likely we are to receive Covid‐19 vaccination? Previous work suggests that moral foundations, particularly purity and liberty, relate to decisions to vaccinate. In addition, research on the moral trade‐off hypothesis suggests value in exploring trade‐offs between foundations. We conducted three studies across the pandemic: at the start of the vaccine rollout (Study 1, N = 170); during delivery (Study 2, N = 328) and 2 years later (Study 3, N = 388). We find that trade‐offs between purity and care and between liberty and care are predictive of higher levels of vaccine reluctance—individuals who endorse purity or liberty more, relative to care, were more reluctant towards Covid‐19 vaccination, less likely to have received a vaccine and have lower intention to get future Covid‐19 vaccines. This research highlights the relevance of moral values, and trade‐offs between them, in vaccine attitudes and decisions.

Predictors of seasonal influenza and COVID-19 vaccination coverage among adults in Tennessee during the COVID-19 pandemic.

The COVID-19 pandemic has convoluted hesitancy toward vaccines, including the seasonal influenza (flu) vaccine. Because of COVID-19, the flu season has become more complicated; therefore, it is important to understand all the factors influencing the uptake of these vaccines to inform intervention targets. This article assesses factors related to the uptake of influenza and COVID-19 vaccines among adults in Tennessee. A cross-sectional, secondary data analysis of 1,400 adults was conducted in Tennessee. The adult sample came from two data sources: Data source 1 completed a baseline survey from January to March 2022, and data source 2 was completed from May to August 2022. Data on vaccine attitudes, facilitators and barriers, and communication needs were collected via random digit dial by Scientific Telephone Samples (STS). Two multivariable logistic regression models were used to estimate adjusted odds ratios (aORs) and 95% confidence intervals (CIs) to predict sociodemographic and overall vaccine-related factors associated with receipt or non-receipt (referent) of COVID-19 and influenza vaccines. Approximately 78% of the adult sample had received the COVID-19 vaccination. A significant positive association for COVID-19 vaccine uptake was seen among those who were older (aged 50-65) (aOR = 1.9; 95% CI: 1.2-3.2), Black (aOR = 2.0; 95% CI:1.3-2.8), and had a college education and higher (aOR = 2.3; 95% CI: 1.5-3.6). However, there was a significant negative association for persons reporting they were extremely religious (aOR = 0.5; 95% CI:0.3-0.9). Over 56% of the adult sample had received the influenza vaccination this season. Those who had a higher annual household income ($80,000+) (aOR = 1.9; 95% CI: 1.3-2.6) and had health insurance (aOR = 2.6; 95% CI: 1.4-4.8) had a significant positive association with influenza vaccine receipt. However, those who were employed part-time or were unemployed had a significant negative association for influenza vaccine receipt (aOR = 0.7; 95% CI: 0.5-0.9). Both COVID-19 and influenza vaccine receipt had strongly significant positive trends with increasing belief in effectiveness and trust (p < 0.0001) and strongly significant negative trends with higher levels of overall vaccine hesitancy (p < 0.0001). Strategies to increase COVID-19 and influenza vaccination should be age-specific, focus on increasing geographical and financial access, and offer tailored messages to address concerns about these vaccines.

Vaccine Hesitancy, Knowledge, and COVID-19 Vaccination in a Sample of Italian and Albanian Healthcare Students Attending an University in Albania.

Vaccine hesitancy (VH) has increased over the past decade with large geographical variations between countries, posing a threat to global public health. This phenomenon is growing in the general population as well as among healthcare workers (HCWs), who are the most reliable source of vaccine-related information for patients. Special attention must therefore be paid to medical students, who are the future HCWs. We conducted a cross-sectional study (November 2022-January 2023) on all the Albanian and Italian students attending medical science courses at the Catholic University "Our Lady of Good Counsel" (Tirane, Albania) to investigate VH and the factors contributing to it (using the Vaccination Attitude Examination Scale-VAX), including COVID-19 vaccination. Vaccine knowledge was assessed using the Zingg and Siegrist Scale. Students were asked to voluntarily answer an anonymous questionnaire. 689 questionnaires were collected (58.8% Albanians, 72.3% female; 70.4% aged 20-25 years; 70.4% attending the Medicine and Surgery course). Generally, students showed low VH, especially Italians (p < 0.001); however, some hesitancy was observed regarding the potential long-term effects of vaccines, especially among Albanians (p < 0.05). The results also showed a significant difference in vaccine knowledge scores between different course years (χ2 = 90.058; df = 40; p = < 0.001) and different degree courses (χ2 = 89.932; df = 40; p = < 0.001). With regard to COVID-19 vaccination, being of Albanian origin significantly increases the risk of not being vaccinated (OR = 7.215; 95%CI 3.816-13.640, p < 0.001), highlighting possible differences in vaccine coverage and policy between the two countries. Vaccine hesitancy should be addressed at early stages during medical sciences courses, in order to protect future healthcare workers, to preserve essential health services, and reduce the risk of further pandemics.