Heerfordt's Syndrome Research Articles

OCULAR IMPORTANCE OF SARCOID

Uveoparotid fever has received so much attention in ophthalmologic literature that the syndrome originally described by Heerfordt is diagnosed promptly. However, from time to time patients are encountered who lack one of the two signs considered essential to the diagnosis, namely, uveitis or parotitis, and in such cases the condition may remain undiagnosed. Another group of patients with a diagnosis of sarcoid may present, in addition to other signs underlying the diagnosis, either or both cardinal signs of uveoparotid fever. The relation between these two diseases has been considered in the recent literature by Longcope and Pierson 1 in their description of sarcoid ; by Hamburger, 2 who was one of the first to recognize uveoparotid fever in this country; by Pautrier, 3 who expressed the belief that the two diseases are different manifestations of the same disease and are not due to tuberculosis, and by Bruins Slot, Goedbloed and Goslings,

UVEO-PAROTID FEVER; WITH CASE REPORT

Case Reports1 December 1936UVEO-PAROTID FEVER; WITH CASE REPORTHERMAN R. PARKER, M.D.HERMAN R. PARKER, M.D.Search for more papers by this authorAuthor, Article, and Disclosure Informationhttps://doi.org/10.7326/0003-4819-10-6-921 SectionsAboutPDF ToolsAdd to favoritesDownload CitationsTrack CitationsPermissions ShareFacebookTwitterLinkedInRedditEmail ExcerptUveo-parotid fever, or Heerfordt's disease, is a comparatively rare affection characterized by (1) an iridocyclitis, (2) a bilateral almost painless swelling of the parotid glands, (3) a low grade chronic fever running a course of from several weeks to two or three years and subject to considerable variations, and (4) by the occurrence of irregular constitutional symptoms. The syndrome may occur at any age, but is most common in the second and third decades, and is slightly more prevalent in females.Of frequent, though not constant, occurrence are: (1) a prodromal stage, lasting for several weeks or months, of general...Bibliography1. HEERFORDT CF: Über eine "Febris Uveoparotidea subchronica," an der Glandula Parotis und der Uvea des Auges lokaliziert und haufig mit Paresen cerebrospinaler Nerver kompliziert, Arch. f. Ophth., 1909, lxx, 254-273. Google Scholar2. MERRILLOAKS HGLW: Uveoparotitis, Am. Jr. Ophth., 1931, xiv, 15-22. CrossrefGoogle Scholar3. GARLANDTHOMPSON HGJG: Uveoparotid tuberculosis, Quart. Jr. Med., 1933, ii, 157-177. Google Scholar4. SAVIN LH: An analysis of the signs and symptoms of 66 published cases of the uveo-parotid syndrome, with details of an additional case, Trans. Ophth. Soc. U. Kingdom, 1934, liv, 549-566. Google Scholar5. GARLANDTHOMPSON HGJG: Uveo-parotid tuberculosis, Lancet, 1934, ii, 743-746. DAVIES, T. A. L.: Uveoparotitis, Lancet, 1934, ii, 746-748. TAIT, C. B. V.: Uveoparotitis, Lancet, 1934, ii, 748-749. LEVIN, P. M.: Neurological aspects of uveoparotitis, Jr. Nerv. and Ment. Dis., 1935, lxxxi, 176-191. COGAN, D. G.: Uveoparotid fever, Am. Jr. Ophth., 1935, xviii, 637-640. COHEN, S. J., and RABINOWITZ, M. A.: Uveoparotitis, Jr. Am. Med. Assoc., 1935, cv, 496-499. TANNER, S. E., and MCCURRY, A. L.: Uveoparotid tuberculosis, Brit. Med. Jr., 1934, ii, 1041-1042. CrossrefGoogle Scholar6. FUCHS E, quoted by MERRILL, H. G., and OAKS, L. W.2 Google Scholar7. HAMBURGERSCHAFFER LPAJ: Uveoparotid fever as a manifestation of Mikulicz's syndrome, Am. Jr. Dis. Child., 1928, xxxvi, 434-444. Google Scholar8. MOHR T, quoted by MERRILL, H. G., and OAKS, L. W.2 Google Scholar9. VINER , quoted by MERRILL, H. G., and OAKS, L. W.2 Google Scholar10. ADAMS , quoted by SAVIN, L. H.4 Google Scholar11. MACKAY G: A case of uveoparotitis with iridocycloplegia, Trans. Ophth. Soc. U. Kingdom, 1917, xxxvii, 208-220. Google Scholar12. RAMSAY AM: Diseases of the uveal tract, Trans. Ophth. Soc. U. Kingdom, 1921, xli, 194-213. Google Scholar13. PARKER G: Uveoparotitic paralysis, Bristol Med. Chir. Jr., 1926, xliii, 73-83. Google Scholar14. SCHALL E: Beitrag zur Aetiologie der Uveoparotitis subchronica, Klin. Monatsbl. f. Augenheilk., 1927, lxxviii, 83. Google Scholar15. UHTHOFF W: Ein Fall von geheilter tuberkuloser Meningitis mit doppelseitiger Iridochoroiditis tuberculosa, Klin. Monatsbl. f. Augenheilk., 1912, l, 474. Google Scholar16. ROENNE J: Über Febris Uveoparotidea, Klin. Monatsbl. f. Augenheilk., 1928, lxxxi, 524. Google Scholar17. GJESSING H: Über Tuberkulose als Aetiologie bei der sog. Febris uveoparotidea (Heerfordt), Klin. Monatsbl. f. Augenheilk., 1918, lx, 249. Google Scholar18. CAVARA C, quoted by GARLAND, H. G., and THOMPSON, J. G.5 Google Scholar19. MCCURRY AL, quoted by SAVIN, L. H.4 Google Scholar This content is PDF only. To continue reading please click on the PDF icon. Author, Article, and Disclosure InformationAffiliations: Greensboro, North Carolina*Received for publication January 20, 1936. PreviousarticleNextarticle Advertisement FiguresReferencesRelatedDetails Metrics 1 December 1936Volume 10, Issue 6Page: 921-926KeywordsFeversInflammationParotid glandsRunning ePublished: 1 December 2008 Issue Published: 1 December 1936 PDF downloadLoading ...

Uveoparotid Tuberculosis: Report of Two Cases

This is a syndrome of rare occurrence, commonly known as uveoparotid fever. Bilateral enlargement of the parotid gland together with chronic uveitis is the essential feature. The ocular inflammation presents the typical picture of chronic tuberculous iridocyclitis. In one of the two cases here reported there was persistent uveitis and mediastinal adenitis. Biopsy of an enlarged supraclavicular lymph node revealed a tuberculous lesion, the histologic features of which conformed exactly to those described in biopsies of the parotid gland and iris in previously reported cases. From the Department of Ophthalmology, Jewish Hospital of Brooklyn.

Uveoparotid Fever: Case Report

A case of uveoparotid fever with the triad of bilateral uveitis, swelling of the parotid glands, and prolonged fever, is reported in a 29-year-old woman. Evidence is advanced pointing to a tuberculous etiology. The case and the disease are discussed in the light of the outstanding literature on the subject. From the Massachusetts Eye and Ear Infirmary. Read before the New England Ophthalmological Society in December, 1934. A case of uveoparotid fever with the triad of bilateral uveitis, swelling of the parotid glands, and prolonged fever, is reported in a 29-year-old woman. Evidence is advanced pointing to a tuberculous etiology. The case and the disease are discussed in the light of the outstanding literature on the subject. From the Massachusetts Eye and Ear Infirmary. Read before the New England Ophthalmological Society in December, 1934.