Uteroplacental Apoplexy Research Articles

Fetal salvage in abruptio placentae

1.1. Premature separation of the normally implanted placenta occurred 254 times in 26,358 deliveries, an incidence of 1:104, with one maternal death.2.2. The uncorrected perinatal mortality rate was 29.84 per cent and there were 2 infants with major congenital abnormalities incompatible with life.3.3. The degree of severity of placental separation was classified according to the criteria of Page, as modified, with 81 cases of Grade 0 severity, 96 cases of Grade 1, 57 cases of Grade 2, and 20 of Grade 3.4.4. There were 42 cases of toxemia of pregnancy, an incidence of 16.5 per cent, with an increased frequency of toxemia in the severe grades.5.5. Some type of active intervention was carried out 153 times with a fetal salvage of 83.5 per cent when fetal heart tones were present on admission to the hospital, while passive management when the fetus was alive resulted in a fetal survival of only 72.8 per cent.6.6. Forty-six cesarean sections were done for fetal or combined fetal and maternal indications with an 82.6 per cent fetal survival.7.7. There were 3 instances of uteroplacental apoplexy and one of coagulation defect.

The experimental production of toxemia of pregnancy

The present experiments represent an attempt to demonstrate under conditions of laboratory control, the production in rabbits of the anatomic lesions which characterize uteroplacental apoplexy in women. Uteroplacental apoplexy, in the words of Couvelaire (1911) who named it, is characterized by “a colossal infiltration of blood in the uterine wall, occurring in the region of attachment, cleaving the muscle bundles and dissociating certain bundles fiber from fiber. The ovaries are riddled with points of hemorrhagic effusion. The broad ligaments are infiltrated with blood. It amounts indeed to a veritable ‘apoplexie utero-placentaire.’” The present experiments therefore involve the production of hemorrhage into the wall of the uterus and placenta which results frequently in premature separation of the placenta.Since injury of this type occurs in women under conditions of obscure etiology, the present problem is: first, to determine whether or not identical anatomic lesions occur in a laboratory animal, and second, to evaluate the various factors introduced under controlled experimental conditions which cause normal pregnancy to terminate in uteroplacental apoplexy.

The principal methods of treating cases of uteroplacental apoplexy: Rauramo, N., and Kahanpaa, V.: Acta obst. & gynec. Scandinav. 20: 243, 1940

The principal methods of treating cases of uteroplacental apoplexy: Rauramo, N., and Kahanpaa, V.: Acta obst. & gynec. Scandinav. 20: 243, 1940

Pathology and surgical treatment of utero-placental apoplexy and ablatio placentae: Batizfalvy, J.: Arch. f. Gynäk. 163: 552, 1937

Pathology and surgical treatment of utero-placental apoplexy and ablatio placentae: Batizfalvy, J.: Arch. f. Gynäk. 163: 552, 1937

Uteroplacental apoplexy: (“Couvelaire” uterus) treated by cervical cesarean section

Uteroplacental apoplexy: (“Couvelaire” uterus) treated by cervical cesarean section

Pregnancy and Labor Subsequent to Abruptio Placentae and Uteroplacental Apoplexy

Pregnancy and Labor Subsequent to Abruptio Placentae and Uteroplacental Apoplexy

Report of a case of uteroplacental apoplexy in accidental hemorrhage

Report of a case of uteroplacental apoplexy in accidental hemorrhage

The Relationship of Uteroplacental Apoplexy to Ablatio Placentae : A Clinical Study

The Relationship of Uteroplacental Apoplexy to Ablatio Placentae : A Clinical Study