Use Of Titanium Implants Research Articles

Trichostatin A enhances the titanium rods osseointegration in osteoporotic rats by the inhibition of oxidative stress through activating the AKT/Nrf2 pathway

The use of titanium implants as fixed supports following fractures in patients with OP can often result in sterile loosening and poor osseointegration. Oxidative stress has been shown to play a particularly important role in this process. While TSA has been reported to facilitate in vivo osteogenesis, the underlying mechanisms remain to be clarified. It also remains unclear whether TSA can improve the osseointegration of titanium implants. This study investigated whether TSA could enhance the osseointegration of titanium rods by activating AKT/Nrf2 pathway signaling, thereby suppressing oxidative stress. MC3T3-E1 cells treated with CCCP to induce oxidative stress served as an in vitro model, while an OVX-induced OP rat model was employed for in vivo analysis of titanium rod implantation. In vitro, TSA treatment of CCCP-treated MC3T3-E1 cells resulted in the upregulation of osteogenic proteins together with increased AKT, total Nrf2, nuclear Nrf2, HO-1, and NQO1 expression, enhanced mitochondrial functionality, and decreased oxidative damage. Notably, the PI3K/AKT inhibitor LY294002 reversed these effects. In vivo, TSA effectively enhanced the microstructural characteristics of distal femur trabecular bone, increased BMSCs mineralization capacity, promoted bone formation, and improved the binding of titanium implants to the surrounding tissue. Finally, our results showed that TSA could reverse oxidative stress-induced cell damage while promoting bone healing and improving titanium rods' osseointegration through AKT/Nrf2 pathway activation.

Failed Dental Implant: When Titanium Fractures.

Despite the widespread use of titanium implants in orthopedic and dental surgeries, concerns have recently emerged regarding potential deformations and fractures after osseointegration. In a recent clinical case, a titanium implant fractured after successful osseointegration. This fracture occurred despite the absence of any significant trauma or excessive external force applied to the area. The fracture was attributed to a combination of factors, including abutment design flaws, material fatigue, and biomechanical stress imposed on the implant during functional loading. This raises concerns about the long-term durability and reliability of titanium implants, particularly in high-stress areas such as the posterior region or weight-bearing bones. An image was made with scanning electron microscopy showing the fracture region near the prosthetic platform and highlighting the knowledge that despite their ductility, titanium implants can fracture.

Difficulties of nasocutaneous fistula repair, following lacrimal outflow system malignancy resection

ABSTRACT Purpose To evaluate the incidence of nasocutaneous fistula (NCF) development, following en bloc resection of lacrimal outflow system malignancies (LOSM), and describe the methods of surgical repair. Methods Retrospective review of all patients who underwent resection of LOSM with reconstruction and post-treatment protocol at the University of Miami between 1997 and 2021. Results Of the 23 included patients, 10 (43%) developed postoperative NCF. All NCFs developed within one year of surgical resection or completion of radiation therapy. NCF was seen more frequently in patients who underwent adjuvant radiation therapy and those who had reconstruction of the orbital wall with titanium implants. All patients underwent at least one revisional surgery to close the NCF, including local flap transposition (9/10), paramedian forehead flap (5/10), pericranial flap (1/10), nasoseptal flap (2/10), and microvascular free flap (1/10). Local tissue transfer, pericranial, paramedian, and nasoseptal forehead flaps failed in most cases. Two patients had long-term closure; one patient who underwent a paramedian flap and a second who underwent a radial forearm free flap, suggesting that well-vascularized flaps may be the most viable option for repair. Conclusions NCF is a known complication, following en bloc resection of lacrimal outflow system malignancies. Risk factors for formation may include adjuvant radiation therapy and use of titanium implants for reconstruction. Surgeons should consider utilizing robust vascular-pedicled flaps or microvascular free flaps for repair of NCF in this clinical scenario.

Survival of Single Immediate Implants and Reasons for Loss: A Systematic Review

Background: Immediate implant placement (IIP) or Type I implants have become more attractive than conventional implant placements as it reduces the number of surgical procedures and allows faster delivery of the final restoration compared to conventional implant placements. However, the survival of Type I implants varies depending on multiple factors. Purpose: To evaluate the survival rate of Type I implants, and to describe the factors influencing their failure. Materials and methods: A developed search strategy was applied to identify randomised controlled trials on single-unit immediate implants including at least six human participants with a minimum follow-up time of 12 months and published between 1 January 1999 and 1 January 2020 in several databases. The data were extracted independently using validated data extraction forms. Information on survival rates, number of implants placed, loading protocols, setting of the study, location of implants in the jaw, antibiotic protocol, grafting methods, and implant geometry were obtained and assessed. Results: Twenty-six randomised controlled trials with an average follow-up time of 24 months (range = 12–120 months) were included and analysed to give a survival rate ranging between 83.7 and 100%. Fifteen studies reported implant failures, of which twelve reported early losses (loss before definitive restoration). Nine early losses were due to lack of osseointegration, two did not report the reason for implant failure, and one was reported as iatrogenic. Of the eleven studies with 100% survival rates, the common trend observed was the use of titanium implants and an antibiotic regimen using amoxicillin. Conclusions: The survival rate for immediate single implant placement ranged from 83.7 to 100%. Implant failure was not consistently reported and when reported, failure due to lack of osseointegration prior to placement of the definitive restoration was the most common descriptor. Other attributed reasons included infection abscess, mobility after immediate loading, and iatrogenic complications.

Toxicity of titanium in dental implants- Implications on patient health and clinical practice

The use of titanium implants in dentistry has become increasingly popular due to their biocompatibility and excellent mechanical properties. However, the release of titanium ions from the implants has the potential to lead to local and systemic toxicity, which may cause implant failure or have negative consequences on the body. In this article, the causes of titanium toxicity are discussed, including implant design, surgical methods, and patient specific elements. It also looks at the possible health hazards of titanium poisoning, such as inflammation, allergic reaction and neurological issues.

Osteogenic and long-term antibacterial properties of Sr/Ag-containing TiO2 microporous coating in vitro and in vivo.

Bacterial infection and poor osseointegration are two critical issues that need to be solved for long-term use of titanium implants. As such, Sr/Ag-containing TiO2 microporous coatings were prepared on a Ti alloy surface in the current study via a single-step microarc oxidation technique. The coatings showed both good cytocompatibility in vitro and biosafety in vivo. Sr/Ag incorporation brought no significant change in the surface micromorphology and physicochemical properties, but endowed the coating with strong osteogenic activity and long-term antibacterial capability in vitro. Furthermore, the osteogenic and antibacterial capability of the coating was also confirmed in vivo. In a rat osseointegration model, new bone formation, implant-bone contact, removal torque and bone mineralization were all significantly increased in the M-Sr/Ag group when compared with those in group M, although they were slightly lower than those in group M-Sr. In a periimplantitis model, no rats suffered infection in the M-Sr/Ag group after 3 months of osseointegration and 5 weeks of bacterial inoculation period, when compared to 100% and 75% infection rates in M and M-Sr groups, respectively. In addition, active bone remodeling and many mesenchymal cells were observed in the M-Sr group, suggesting good bone regeneration potential in Sr-containing coatings in the case of controlled periimplantitis. Overall, the Sr/Ag-containing TiO2 microporous coating is valuable for preventing periimplantitis and improving implant reosseointegration, and is therefore promising for long-term and high quality use of titanium implants.

Management of failed stainless steel implants in the oromaxillofacial region of dogs.

Management of complications of fracture fixation in the oromaxillofacial (OMF) region may present a diagnostic and therapeutic challenge. While titanium and stainless steel implants have been utilized in successful fracture fixation in the OMF region, the use of titanium implants is preferred due to the superior intrinsic properties of titanium. Nonetheless, stainless steel materials are still used due to their availability and familiarity. In the present methods report, we describe our approach to the management of failed stainless steel plates and screws used to treat traumatic injuries in the OMF region. Furthermore, we exemplify our approach with five dogs that exhibited complications of stainless steel implants in the OMF region and their subsequent management. In those cases, all failed implants were removed. Reconstruction with a combination of recombinant human bone morphogenetic protein-2 (rhBMP-2) and titanium implants was utilized in two cases while a mandibulectomy was performed in one case. Three cases required removal of the stainless-steel implant with no additional surgical therapy. We conclude that the success of treatment of failed stainless steel implants depends on the use of advanced imaging findings, appropriate antimicrobial therapy, as well as potentially regenerative reconstructive surgery.

Titanium Implants in the Nose: State of the Art.

Titanium implants in the head have been used widely for decades. Dental implants as well as titanium plates, screws, and mesh have been an integral part of dental and maxillofacial surgery. In the nose, titanium implants were started in 2003. Their purpose is to increase structure and stiffness to nasal cartilages widening the airway. This overview describes the use of titanium implants in the various locations in the nose. We concentrate on three locations: Breathe Implants on the upper lateral cartilage to widen the internal nasal valve, modified breathe implants in the lower lateral nasal wall fixed to the piriform aperture as batten grafts to widen the external nasal valve, and flattened breathe implants as titanium septum plates to straighten and strengthen the nasal septum.

A systematic review of the use of titanium versus stainless steel implants for fracture fixation.

Background:Controversy exists regarding the use of titanium and stainless steel implants in fracture surgery. To our knowledge, no recent, comprehensive review on this topic has been reported.Purpose:To perform a systematic review of the evidence in the current literature comparing differences between titanium and stainless steel implants for fracture fixation.Methods:A systematic review of original research articles was performed through the PubMed database using PRISMA guidelines. Inclusion criteria were English-language studies comparing titanium and stainless steel implants in orthopaedic surgery, and outcome data were extracted.Results:The search returned 938 studies, with 37 studies meeting our criteria. There were 12 clinical research articles performed using human subjects, 11 animal studies, and 14 biomechanical studies. Clinical studies of the distal femur showed the stainless steel cohorts had significantly decreased callus formation and an increased odds radio (OR 6.3, 2.7-15.1; P < .001) of nonunion when compared with the titanium plate cohorts. In the distal radius, 3 clinical trials showed no implant failures in either group, and no difference in incidence of plate removal, or functional outcome. Three clinical studies showed a slightly increased odds ratio of locking screw breakage with stainless steel intramedullary nails compared with titanium intramedullary nails (OR 1.52, CI 1.1-2.13).Conclusion:Stainless steel implants have equal or superior biomechanical properties when compared with titanium implants. However, there is clinical evidence that titanium plates have a lower rate of failure and fewer complications than similar stainless steel implants in some situations. Although our review supports the use of titanium implants in these clinical scenarios, we emphasize that further prospective, comparative clinical studies are required before the conclusions can be made.

Features of Bone Regeneration of the Jaws Alveolar Ridge Using Hydroxyapatite-Based Material

Background. Currently, using of osteointegrated titanium implants has become a key component for restoring lost function in various areas of clinical medicine. The actual issue remains preservation or reconstruction of bone tissue for optimal use of titanium implants in traumatology and orthopedics, as well as in maxillofacial surgery. One of the most common grafts are hydroxyapatite-based material with various inclusions, for example, an antibiotic.The aim of the study is to characterize the regeneration of bone tissue of the jaws alveolar ridge using the hydroxyapatite-based material “Collapan-L” in clinical practice.Material and Methods. The study of the material “Collapan-L” (Intermedapatit, Russia) using involved 30 patients with a diagnosis “chronic periodontitis of the tooth”. Patients underwent complex surgical and orthopedic treatment to restore masticatory function. At the first stage, teeth were removed with the “Collapan-L” material used to preserve the alveolus. 4 months after extraction, dental implantation was performed with simultaneous trephine biopsy from the augmentation zone for histomorphometric analysis. At the stage of implant placement and before prosthetics the stability dynamics was measured.Results. The study involved 42 tissue samples obtained at periods from 9 to 32 weeks after removal. The morphological assessment of bone tissue from the implantation zone determined that after 4 months trabeculae from the newly formed bone, including small fragments of biomaterial, were revealed; at the same time, there were signs of biodegradation of the implanted material fragments, there was no inflammatory infiltrate. After 6 months in a significant part of cases the granules of bone material were not found, which indicates a pronounced osseointegration of the material. In its structure, the formed bone tissue differences barely noticeable from the native one, which allows us to conclude that by the time of 24 weeks, the processes of reparative osteogenesis in the alveolus are completed.Conclusion. Histological examination and assessment of changes in the stability showed that using of bone replacement material after tooth extraction can increase the regenerative potential of bone tissue, avoid additional surgical interventions to increase the volume of bone tissue in the area of future implantation, and the formed bone tissue is close in its structure to the native one.

Срединная TiMESH-кольпоррафия с лигатурной трансобтураторной фиксацией культи влагалища как способ хирургического лечения постгистерэктомической тазовой грыжи

The analysis of clinical observation of 4 patients aged 68–78 years with post-hysterectomy pelvic hernia who were operated with the use of titanium implants and transobturator ligature fixation of the vaginal cuff according to the original technique is presented. Dynamic follow-up for 3–12 months after surgery showed the absence of pelvic organ prolapse during gynecological examination, Valsalva maneuver, and transperineal ultrasound. The questionnaire survey of patients showed their satisfaction with the results of surgery and improvement of their quality of life. Conclusion. Median TiMESH colporrhaphy with transobturator ligature fixation of the vaginal cuff in patients of elderly and senile age with post-hysterectomy pelvic hernia when slightly prolonging the operation duration contributes to strengthening and firm consolidation of the vaginal walls, elevation of the vaginal cuff and adjacent organs, improving the condition of the surgical scar and, therefore, improving patients’ quality of life and preventing disease recurrence. Key words: post-hysterectomy pelvic hernia, median TiMESH colporrhaphy, transobturator ligature fixation of the vaginal cluff

Use of Impedance Spectroscopy for the Characterization of In-Vitro Osteoblast Cell Response in Porous Titanium Bone Implants

The use of titanium implants with adequate porosity (content, size and morphology) could solve the stress shielding limitations that occur in conventional titanium implants. Experiments to assess the cellular response (adhesion, proliferation and differentiation of osteoblasts) on implants are expensive, time-consuming and delicate. In this work, we propose the use of impedance spectroscopy to evaluate the growth of osteoblasts on porous titanium implants. Osteoblasts cells were cultured on fully-dense and 40 vol.% porous discs with two ranges of pore size (100–200 μm and 355–500 μm) to study cell viability, proliferation, differentiation (Alkaline phosphatase activity) and cell morphology. The porous substrates 40 vol.% (100–200 µm) showed improved osseointegration response as achieved more than 80% of cell viability and higher levels of Cell Differentiation by Alkaline Phosphatase (ALP) at 21 days. This cell behavior was further evaluated observing an increase in the impedance modulus for all study conditions when cells were attached. However, impedance levels were higher on fully-dense due to its surface properties (flat surface) than porous substrates (flat and pore walls). Surface parameters play an important role on the global measured impedance. Impedance is useful for characterizing cell cultures in different sample types.

Surgical correction of prolapse of anterior wall of the vagina and cervix using titanium mesh implants

Background: Regardless of a variety of surgical techniques and hi-tech materials for pelvic prolapse treatment, there is no decrease in the disease recurrences.&#x0D; Aims: Evaluation of the efficacy of the developed method of surgical correction of IIIV degree colpoptosis anterior combined with IIIII degree C-prolapse with the use of titanium mesh implants in reproductive, pre- and postmenopausal female patients.&#x0D; Methods: Female patients (group I, n = 25) with colpoptosis anterior and cervical prolapse were examined and operated on according to the developed know-how technique with the use of titanium mesh implants. Evaluation of the efficacy of surgical correction of the disease was performed using questioning, pelvic exam with Valsalva manoeuvre, transvaginal and transperineal ultrasound, pelvis MRI. The findings were compared with the result of surgical treatment of 46 (group II) and 32 (group III) female patients operated on without the use of titanium implants. After surgical treatment according to the three-stage surgical program that provides for multifocal fixation of anatomical formations with the use of titanium implants, the case follow-up was performed in 321 months.&#x0D; Results: Questioning the patients in group I demonstrated their satisfaction with the surgical treatment results that positively affected the quality of life, mood, and contributed to an increase in sexual activity and community commitment. Check-up showed that the surgical correction of prolapse was completely preserved in the patients of group I during 1821 months. Pelvic exam at rest and with Valsalva manoeuvre, transvaginal and transperineal ultrasound, pelvis MRI did not reveal any significant extrusion of the pelvic organs or titanium implants. No mesh-associated complications were observed during the follow-up. Recurrence of genital prolapse was diagnosed in 12 (26%) patients of group II, mesh-associated complications were detected in 6 (18.8%) women of group III.&#x0D; Conclusions: The preserving three-stage surgical program, developed by us, contributed to optimize the results of surgical treatment, decrease the rate of the disease recurrence, and reduce the risk of the development of mesh-associated complications.

Flame-sprayed strontium- and magnesium-doped hydroxyapatite on titanium implants for osseointegration enhancement

Strontium (Sr) and magnesium (Mg) have been reported to promote osteoblastic cell proliferation and to accelerate bone formation. However, the biofunctional effect on osseointegration caused by coating dental implants with hydroxyapatite (HA) incorporating both of these elements has not been investigated to date. The aim of this study was to examine bone formation and osseointegration in Sr- and Mg-doped HA-coated titanium implants. In this study, the flame-spraying technique was used to deposit Sr- and Mg-doped HA onto titanium discs and implants. The biocompatibility and alkaline phosphatase (ALP) activity of human embryonic palatal mesenchymal pre-osteoblasts on titanium discs was evaluated. In addition, the expression of the osteogenesis gene and the protein expression of Runt-related transcription factor 2 (RUNX2), osteopontin (OPN), and osteocalcin (OCN) on titanium discs were determined by using real-time polymerase chain reaction assays, Western blot analysis, and enzyme-linked immunosorbent assays. Ultimately, the effects of Sr- and Mg-doped HA on the osseointegration of implants were examined in beagle dogs. The results showed that of the groups tested, the 5Sr5Mg-HA group exhibited the highest biocompatibility, ALP activity, and mRNA and protein expression of RUNX2, OPN, and OCN. Prominent new bone ingrowth with osteoblasts and osteoid tissue was found in the 5Sr5Mg-HA group at 4 weeks and 8 weeks. In addition, the highest bone-to-implant contact ratio was found in the 5Sr5Mg-HA group compared to other groups at 8 weeks in beagle dogs. The results show the potential of using 5Sr5Mg-HA coating on dental implants for enhanced osseointegration. Statement of SignificanceOsseointegration is assessed according to the extent of bone-to-implant contact and is an indication of implant success. This study is the first to report that flame-sprayed Sr- and Mg-doped HA coatings on titanium surfaces enhance osseointegration and new bone apposition in a beagle dog model. Therefore, the use of titanium implants incorporating Sr and Mg might be advantageous for patients with a low bone density.

Biomimetic Enhancement of Bone Graft Reconstruction.

With aging populations and increasing oral rehabilitation, use of dental implants for oral reconstruction is increasing. Adequate hard/soft tissue are required to support use of titanium implants. Bone augmentation is sometimes a necessary procedure to supplement existing alveolar bone. With a wide variety of biomaterials available for clinical use, we focus on the enhancement of bone graft materials, targeting new technologies with potential clinical use. Clinical indications supported by research studies are provided for platelet-rich fibrin, various growth factors, and newly emerging scaffolds. Interestingly, modified biomaterials are being developed and have potential clinical use as more data become available.

Are titanium implants actually safe for magnetic resonance imaging examinations?

Magnetic resonance imaging (MRI) is widely used for the diagnosis, staging, and follow-up of diseases. MRI is a very useful diagnostic tool for musculoskeletal and cerebrovascular imaging, because it has excellent soft tissue contrast and is considered to be safer than other modalities, as it does not expose the body to radiation [1]. However, MRI is not without risks. The presence of a metal implant in the patient’s body during an MRI scan can be dangerous due to excessive magnetic field interactions. Developments in medicine have led to the use of various implants, such as dental and orthopedic implants, in our bodies [2]. In the field of craniofacial surgery, the use of titanium plates and screws in open reduction and internal fixation procedures has exploded since the late 20th century, and titanium is now considered to be the material of choice for implants. Titanium plates are frequently used for cranioplasty, reconstruction of the facial bones, and reconstruction of the orbital bone, because they yield excellent results without posing any major problems in terms of biosafety [3]. Some physicians, however, have questioned whether titanium implants are actually safe for MRI examinations. The greater the number of elderly patients, the higher the probability of conducting brain MRI due to cerebrovascular disease. This has led to the question of whether widespread use of titanium implants in the craniofacial region is acceptable given the likelihood that patients will undergo brain MRI in the future. In this paper, we present the mechanism of MRI and its relationship to metals, especially titanium, and review the concerns that have been raised about titanium materials in MRI.

Assessment of Immediate Loading with Mini-Implant Anchorage in Critical Anchorage Cases Between Stainless Steel Versus Titanium Miniscrew Implants: A Controlled Clinical Trial

Anchorage in orthodontics is a decisive factor in progress and outcome of a case. With the advent of mini-implants, great advances have been achieved in terms of absolute anchorage. The following article compares the use of stainless steel and titanium implants in a split mouth, controlled clinical study, having direct in vivo comparison. 10 patients were selected for the same and carefully evaluated. The mini-implants were placed in the buccal mucosa, under local anaesthesia, after radiographic safe zone selection. The loading protocol was standardised with low immediate load, followed by incremental load up to 150g. For the study, the cases planned with en-masse retraction of the anteriors into the premolar space were selected for the uniformity in mechanics. The results are discussed with comparative analysis between the two materials and their success rate individually and in relation to upper and lower jaw respectively. In results, a significant success rate has been found with use of titanium implants, with higher implant failure in upper jaw compared to lower jaw.

The Redox Balance in Erythrocytes, Plasma, and Periosteum of Patients with Titanium Fixation of the Jaw.

Titanium miniplates and screws are commonly used for fixation of jaw fractured or osteotomies. Despite the opinion of their biocompatibility, in clinical practice symptoms of chronic inflammation around the fixation develop in some patients, even many years after the application of miniplates and screws. The cause of these complications is still an unanswered question. Taking into account that oxidative stress is one of the toxic action of titanium, we have evaluated the antioxidant barrier as well as oxidative stress in the erythrocytes, plasma and periosteum covering the titanium fixation of the jaw. The study group was composed of 32 patients aged 20–30 with inserted miniplates and screws. The antioxidant defense: catalase (CAT), glutathione peroxidase (GPx), superoxide dismutase-1 (SOD1), uric acid (UA), total antioxidant capacity (TAC), as well as oxidative damage products: advanced oxidation protein products (AOPP), advanced glycation end products (AGE), dityrosine, kynurenine, N-formylkynurenine, tryptophan, malondialdehyde (MDA), 4-hydroxynonenal (4-HNE), total oxidant status (TOS), and oxidative status index (OSI) were evaluated. SOD1 activity (↓37%), and tryptophan levels (↓34%) showed a significant decrease while AOPP (↑25%), TOS (↑80%) and OSI (↑101%) were significantly elevated in maxillary periosteum of patients who underwent bimaxillary osteotomies as compared to the control group. SOD-1 (↓55%), TAC (↓58.6%), AGE (↓60%) and N-formylkynurenine (↓34%) was statistically reduced while AOPP (↑38%), MDA (↑29%), 4-HNE (↑114%), TOS (↑99%), and OSI (↑381%) were significantly higher in the mandibular periosteum covering miniplates/screw compared with the control tissues. There were no correlations between antioxidants and oxidative stress markers in the periosteum of all patients and the blood. As exposure to the Ti6Al4V titanium alloy leads to disturbances of redox balance in the periosteum surrounding titanium implants of the maxilla and the mandible so antioxidant supplementation should be recommended to the patients undergoing treatment of dentofacial deformities with the use of titanium implants. The results we obtained may also indicate a need to improve the quality of titanium jaw fixations through increase of TiO2 passivation layer thickness or to develop new, the most highly biodegradable materials for their production.

Exposure of titanium implants after cranioplasty: A matter of long-term consequences

Abstract Although the use of titanium implants in cranioplasty has recently become common, long-term results of this strategy are sometimes difficult to manage. The aim of this study was to clarify the characteristics of patients developing exposure of titanium implants. Records of eight patients with exposure of titanium implants were reviewed. Patient ages ranged from 41 to 77 (mean, 56.8) years. Two patients were male, and six were female. The periods from implantation to exposure of titanium implants ranged from 5 to 87 (mean, 30.5) months. In seven cases, titanium mesh cranioplasty was performed after postcraniotomy infections. The titanium implants were removed in all cases. Scalp tissue was closed by applying a primary closure technique in five cases, though scalp reconstruction was performed with a rotation flap in the other three cases involving large scalp ulceration. Although the use of titanium implants is convenient, the indications should be carefully considered, especially in cases with postoperative surgical site infections and in patients with thin scalp skin. For these patients, long-term follow up is necessary.

Возможности улучшения функции и косметики культей пальцев кисти методом оссеоинтеграции

Relevance The work deals with the challenging problems of improving the function and aesthetic appearance of the finger stumps using a surgical technology of osseointegration. Purpose To present preliminary results of osseointegration with the use of titanium implants and exoprostheses for finger stumps. Material and methods Osseointegration was performed in order to improve the function and aesthetic appearance of 17 phalangeal finger stumps in 8 patients at the age of 15 to 57 years who underwent treatment at the FSBI RISC for RTO of the RF ministry of health in 2014. Results Osseointegration that was assessed with clinical and radiographic methods, bench tests, and DASH scale resulted in positive short-term outcomes. Conclusion Osseointegrated finger prostheses for defects at the phalangeal level improve hand functions and appearance within a short period of time. The method of osseointegration is strategically important for management of large limb segment amputations and high levels of truncation. It is relevant to develop domestic implants that will optimize treatment terms, its results, and further prosthetic application.