Use Of Stable Isotope Techniques Research Articles

Evaluation of zinc metabolism with use of stable-isotope techniques: implications for the assessment of zinc status

Zinc stable isotopes can be applied to the identification of populations at risk for zinc deficiency and to moni-toring the effects of zinc intervention studies designed to improve zinc nutriture. Techniques using these isotopes can provide information on how effectively the intestine is absorbing exogenous dietary zinc and conserving endogenous zinc. They can also yield estimates of the quantity of readily exchangeable zinc in the body. Data derived from stable-isotope studies can provide extensive information on zinc status and the bioavailability of dietary zinc, allowing researchers to relate zinc intake to physiologic and pathologic conditions. Application of these techniques in longitudinal studies can provide quantitative data on the effectiveness of prevention programs such as simple community measures aimed at reducing dietary phytate and zinc fortification and supplementation programs. Further, judicious application of zinc stable-isotope techniques could make an important contribution to progress toward the eradication of zinc deficiency in infants and young children in the developing world. Am J Clin Nutr 1998(suppl);68:410S–3S.

The role of zinc and vitamin A in persistent diarrhea among infants and young children.

The role of zinc and vitamin A in persistent diarrhea among infants and young children.

Mineral Absorption in 6-Month-Old Breast-Fed Infants. 3

Background: There are minimal data regarding mineral absorption in older infants who are fed solid foods (beikost) in addition to milk. Use of stable isotope techniques allows for the measurement of mineral absorption in this population.

CONTRIBUTION OF AMINOACID CATABOLISM TO PROPIONATE PRODUCTION IN METHYLMALONIC ACIDAEMIA

The rates of propionate production and aminoacid catabolism in 5 children with methylmalonic acidaemia were measured by use of stable isotope techniques. Total propionate production was 55-186 μmol/kg per h, to which the maximum contribution of protein catabolism was 10-35 μmol/kg per h (5-40%). These findings indicate important sources of propionate other than protein catabolism, which may account for the limited efficacy of dietary protein restriction in treatment of methylmalonic acidaemia.

Biosynthesis of antibiotics of the virginiamycin family. 1. Biosynthesis of virginiamycin M1: determination of the labeling pattern by the use of stable isotope techniques

ADVERTISEMENT RETURN TO ISSUEPREVArticleNEXTBiosynthesis of antibiotics of the virginiamycin family. 1. Biosynthesis of virginiamycin M1: determination of the labeling pattern by the use of stable isotope techniquesDavid G. I. Kingston and Michael X. KolpakCite this: J. Am. Chem. Soc. 1980, 102, 18, 5964–5966Publication Date (Print):August 1, 1980Publication History Published online1 May 2002Published inissue 1 August 1980https://doi.org/10.1021/ja00538a070RIGHTS & PERMISSIONSArticle Views129Altmetric-Citations20LEARN ABOUT THESE METRICSArticle Views are the COUNTER-compliant sum of full text article downloads since November 2008 (both PDF and HTML) across all institutions and individuals. These metrics are regularly updated to reflect usage leading up to the last few days.Citations are the number of other articles citing this article, calculated by Crossref and updated daily. Find more information about Crossref citation counts.The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. Clicking on the donut icon will load a page at altmetric.com with additional details about the score and the social media presence for the given article. Find more information on the Altmetric Attention Score and how the score is calculated. Share Add toView InAdd Full Text with ReferenceAdd Description ExportRISCitationCitation and abstractCitation and referencesMore Options Share onFacebookTwitterWechatLinked InReddit PDF (404 KB) Get e-Alerts Get e-Alerts